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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU01312


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU01312
General rule information [?]

Accession PRU01312
Dates 10-MAR-2021 (Created)
10-MAR-2021 (Last updated, Version 3)
Data class Domain;
Predictors PROSITE; PS51967; COV_VIROPORIN_3A_CD
Name Coronavirus (CoV) 3a-like viroporin transmembrane (CD) domain
Function 3a-like accessory proteins are transmembrane proteins of the viroporin family that form ion channels in the host membrane and have been implicated in inducing apoptosis, pathogenicity, and virus release. 3a-like viroporins contain a transmembrane domain (TM) and a cytosolic domain (CD).
Scope(s) Viruses
Orthocoronavirinae
Example(s) P0DTC3;

Propagated annotation [?]

Features [?]

From: PS51967
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="CoV 3a-like viroporin CD #"

Additional information [?]

Size range 50-100 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]