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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU01323


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PURL: https://purl.expasy.org/prosite/rule/PRU01323
General rule information [?]

Accession PRU01323
Dates 15-JUL-2021 (Created)
15-JUL-2021 (Last updated, Version 2)
Data class Domain;
Predictors PROSITE; PS51979; YEBF_CMI
Name YebF/Cmi domain
Function ColM-producing strains are protected from the toxin that they produce by coexpression of a specific immunity protein, named Cmi. Cmi is anchored in the cytoplasmic membrane with an alpha-helix and contains a periplasmic domain that shows sequence similarity to YebF-like proteins which are known to be secreted into the external medium by some Gram-negative bacteria. The YebF/Cmi domain is typified by two cysteine residues, required for Cmi folding and structure stabilization.
Scope(s) Bacteria
Enterobacterales
Example(s) Q57NB9;

Propagated annotation [?]

Keywords [?]

case <FTTag:disulf>
Disulfide bond
end case

Features [?]

From: PS51979
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="YebF/Cmi #"
DISULFID 5 78 disulf C-x*-C

Additional information [?]

Size range 85-95 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]