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ProRule PRU01325


General rule information [?]

Accession PRU01325
Dates 22-JUL-2021 (Created)
19-NOV-2022 (Last updated, Version 3)
Data class Domain;
Predictors PROSITE; PS51981; ZF_RZ
Name Zinc finger RZ-type
Function The ubiquitylation of LPS on Salmonella that invade the cytosol relies on the RZ-type zinc finger in the E3 module of RNF213.
Scope(s) Eukaryota
Euteleostomi
Example(s) Q9P2E3 (ZNFX1_HUMAN);

Propagated annotation [?]

Keywords [?]

Zinc-finger
case <Feature:PS51981:24=[CH]> and <Feature:PS51981:28=[CH]> and <Feature:PS51981:44=[CH]> and <Feature:PS51981:47=[CH]>
Ubl conjugation pathway
Metal-binding
Zinc
end case

Features [?]

From: PS51981
Key From To Description Tag Condition FTGroup
case <Feature:PS51981:24=C> and <Feature:PS51981:28=H> and <Feature:PS51981:44=C> and <Feature:PS51981:47=C>
ZN_FING from to /note="RZ-type #"
else case <Feature:PS51981:24=[CH]> and <Feature:PS51981:28=[CH]> and <Feature:PS51981:44=[CH]> and <Feature:PS51981:47=[CH]>
ZN_FING from to /note="RZ-type #; atypical"
else
ZN_FING from to /note="RZ-type #; degenerate"
end case
ACT_SITE 35 35 /note="Nucleophile" C
BINDING 24 24 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 [CH] 1
BINDING 28 28 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 [CH] 1
BINDING 44 44 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 [CH] 1
BINDING 47 47 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 [CH] 1

Additional information [?]

Size range 70-75 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.



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UniProtKB rule member sequences [?]