Due to maintenance work, this service will be unavailable from
Mon Nov 11 17:30 until
Tue Nov 12 09:00
CET.
Apologies for the inconvenience.
ProRule PRU01325
General rule information
[?]
| Accession | PRU01325 |
| Dates | 22-JUL-2021 (Created)
19-NOV-2022 (Last updated, Version 3) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51981; ZF_RZ |
Name | Zinc finger RZ-type |
| Function | The ubiquitylation of LPS on Salmonella that invade the cytosol relies on the RZ-type zinc finger in the E3 module of RNF213. |
| Scope(s) |
Eukaryota Euteleostomi |
| Example(s) | Q9P2E3 (ZNFX1_HUMAN); |
Propagated annotation
[?]
Keywords
[?]
| Zinc-finger | |
| case <Feature:PS51981:24=[CH]> and <Feature:PS51981:28=[CH]> and <Feature:PS51981:44=[CH]> and <Feature:PS51981:47=[CH]> | |
| Ubl conjugation pathway | |
| Metal-binding | |
| Zinc | |
| end case | |
Features
[?]
| From: PS51981 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| case <Feature:PS51981:24=C> and <Feature:PS51981:28=H> and <Feature:PS51981:44=C> and <Feature:PS51981:47=C> | ||||||||||||
| ZN_FING | from | to | /note="RZ-type #" | |||||||||
| else case <Feature:PS51981:24=[CH]> and <Feature:PS51981:28=[CH]> and <Feature:PS51981:44=[CH]> and <Feature:PS51981:47=[CH]> | ||||||||||||
| ZN_FING | from | to | /note="RZ-type #; atypical" | |||||||||
| else | ||||||||||||
| ZN_FING | from | to | /note="RZ-type #; degenerate" | |||||||||
| end case | ||||||||||||
| ACT_SITE | 35 | 35 | /note="Nucleophile" | C | ||||||||
| BINDING | 24 | 24 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1" |
[CH] | 1 | |||||||
| BINDING | 28 | 28 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1" |
[CH] | 1 | |||||||
| BINDING | 44 | 44 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1" |
[CH] | 1 | |||||||
| BINDING | 47 | 47 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1" |
[CH] | 1 | |||||||
Additional information
[?]
| Size range | 70-75 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
[?]
- UniProtKB/Swiss-Prot sets
Eukaryota [6] All [ 6 ]
- Retrieve set of proteins with 3D structure for this domain