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PRU01325


General rule information [?]

Accession PRU01325
Dates 22-JUL-2021 (Created)
19-NOV-2022 (Last updated, Version 3)
Data class Domain
Predictors PROSITE; PS51981; ZF_RZ
Name Zinc finger RZ-type
Function The ubiquitylation of LPS on Salmonella that invade the cytosol relies on the RZ-type zinc finger in the E3 module of RNF213.

Propagated annotation [?]


Keywords [?]

Zinc-finger
case <Feature:PS51981:24=[CH]> and <Feature:PS51981:28=[CH]> and <Feature:PS51981:44=[CH]> and <Feature:PS51981:47=[CH]>
Ubl conjugation pathway
Metal-binding
Zinc
end case


Features [?]

case <Feature:PS51981:24=C> and <Feature:PS51981:28=H> and <Feature:PS51981:44=C> and <Feature:PS51981:47=C>
From: PS51981
Key     From     To       Description   Tag   Condition   FTGroup
ZN_FING     from     to       RZ-type #        
else case <Feature:PS51981:24=[CH]> and <Feature:PS51981:28=[CH]> and <Feature:PS51981:44=[CH]> and <Feature:PS51981:47=[CH]>
ZN_FING     from     to       RZ-type #; atypical        
else
ZN_FING     from     to       RZ-type #; degenerate        
end case

ACT_SITE     35     35       Nucleophile     C  
BINDING     24     24       /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1     [CH]   1
BINDING     28     28       /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1     [CH]   1
BINDING     44     44       /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1     [CH]   1
BINDING     47     47       /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1     [CH]   1

Additional information [?]

Size range 70-75 amino acids
Related rules None
Repeats 1
Topology Undefined
Example Q9P2E3 (ZNFX1_HUMAN)
Scope
Eukaryota; Euteleostomi
Comments None

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.


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UniProtKB rule member sequences [?]