ProRule PRU01340
General rule information
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| PURL | https://purl.expasy.org/prosite/rule/PRU01340 |
| Accession | PRU01340 |
| Dates | 4-APR-2022 (Created)
2-MAY-2022 (Last updated, Version 2) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51996; TR_MART |
Name | Toxin-related mono-ADP-ribosyltransferase (TR mART) core domain |
| Function | Most known mARTs transfer ADP-ribose onto arginine residues. Some enzymatically inactive mART domains, for example, the N-terminal domains of C2 and VIP2 toxins, have acquired a new, protein-binding function. |
| Scope(s) |
Eukaryota Euteleostomi Bacteria Viruses |
| Example(s) | P21454 (SPVB_SALTM); |
Propagated annotation
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Keywords
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| Transferase | |
| NAD | |
| end case | |
Gene Ontology
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| case <FTGroup:1> | |
| GO:0106274; Molecular function:NAD+-protein-arginine ADP-ribosyltransferase activity | |
Cross-references
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| PROSITE | PS01291; ART; 0-1; |
Features
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| From: PS51996 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="TR mART core #" | |||||||||
| ACT_SITE | 89 | 89 | R | 1 | ||||||||
| ACT_SITE | 116 | 116 | S | 1 | ||||||||
| ACT_SITE | 157 | 157 | E | 1 | ||||||||
Additional information
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| Size range | 170-260 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Bacteria [17] Eukaryota [19] Viruses [8] All [ 44 ]
- Retrieve set of proteins with 3D structure for this domain