General rule information
[?]
Accession |
PRU01341 |
Dates |
13-APR-2022 (Created) 13-APR-2022 (Last updated, Version 1) |
Predictors |
PROSITE; PS51997; UPF1_CH_RICH
|
Name |
UPF1 cysteine-histidine-rich (CH-rich) domain |
Function |
In its N-terminal region, Upf1 has a conserved cysteine-histidine- rich (CH-rich) domain, while centrally it possesses the seven conserved motifs characteristic of eukaryotic group I RNA helicases. The Upf1 CH-rich domain has a cis-inhibitory effect on the ATPase activity and is also the region that binds Upf2. |
Propagated annotation
[?]
case <FTGroup:1> or <FTGroup:2> or <FTGroup:3>
GO:0046872; Molecular function: metal ion binding.
GO:0008270; Molecular function: zinc ion binding.
end case
From: PS51997 |
Key
|
|
From
|
|
To
|
|
Description
|
|
Tag
|
|
Condition
|
|
FTGroup
|
DOMAIN
|
|
from
|
|
to
|
|
Upf1 CH-rich #
|
|
|
|
|
|
|
REGION
|
|
9
|
|
41
|
|
C3H
|
|
|
|
|
|
1
|
METAL
|
|
9
|
|
9
|
|
Zinc #1
|
|
|
|
C
|
|
1
|
METAL
|
|
12
|
|
12
|
|
Zinc #1
|
|
|
|
C
|
|
1
|
METAL
|
|
31
|
|
31
|
|
Zinc #1
|
|
|
|
C
|
|
1
|
METAL
|
|
41
|
|
41
|
|
Zinc #1
|
|
|
|
H
|
|
1
|
REGION
|
|
23
|
|
51
|
|
CC/SHH/C
|
|
|
|
|
|
2
|
METAL
|
|
23
|
|
23
|
|
Zinc #2
|
|
|
|
C
|
|
2
|
METAL
|
|
26
|
|
26
|
|
Zinc #2
|
|
|
|
[CS]
|
|
2
|
METAL
|
|
45
|
|
45
|
|
Zinc #2
|
|
|
|
H
|
|
2
|
METAL
|
|
51
|
|
51
|
|
Zinc #2
|
|
|
|
[HC]
|
|
2
|
REGION
|
|
69
|
|
99
|
|
C4
|
|
|
|
|
|
3
|
METAL
|
|
69
|
|
69
|
|
Zinc #3
|
|
|
|
C
|
|
3
|
METAL
|
|
72
|
|
72
|
|
Zinc #3
|
|
|
|
C
|
|
3
|
METAL
|
|
95
|
|
95
|
|
Zinc #3
|
|
|
|
C
|
|
3
|
METAL
|
|
99
|
|
99
|
|
Zinc #3
|
|
|
|
C
|
|
3
|
Additional information
[?]
Size range |
150-340 amino acids |
Related rules |
None |
Repeats |
1 |
Topology |
Undefined |
Example |
Q09820 (RENT1_SCHPO) |
Scope |
Eukaryota |
Comments |
None |
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