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annotation rule: PRU01343

General rule information [?]

Accession PRU01343
Dates 18-MAY-2022 (Created)
19-NOV-2022 (Last updated, Version 2)
Data class Domain
Predictors PROSITE; PS51999; ZF_GRF
Name Zinc finger GRF-type
Function GRF-ZFs are nucleic acid interaction modules and in several cases these motifs have been shown to enhance enzymatic activity.

Propagated annotation [?]


Gene Ontology [?]

case <FTGroup:1>
GO:0008270; Molecular function: zinc ion binding.

Keywords [?]

Metal-binding
Zinc
end case

Zinc-finger

Features [?]

case <Feature:PS51999:1=[C]> and <Feature:PS51999:3=[HC]> and <Feature:PS51999:26=[C]> and <Feature:PS51999:38=[C]>
From: PS51999
Key     From     To       Description   Tag   Condition   FTGroup
ZN_FING     from     to       GRF-type #        
else case <Feature:PS51999:1=[CH]> and <Feature:PS51999:3=[CH]> and <Feature:PS51999:26=[CH]> and <Feature:PS51999:38=[CH]>
ZN_FING     from     to       GRF-type #; atypical        
else
ZN_FING     from     to       GRF-type #; degenerate        
end case

BINDING     1     1       /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1     [CH]   1
BINDING     3     3       /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1     [CH]   1
BINDING     26     26       /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1     [CH]   1
BINDING     38     38       /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1     [CH]   1

Additional information [?]

Size range 35-65 amino acids
Related rules None
Repeats 1
Topology Undefined
Example Q6DCD7 (ZCHC4_XENLA)
Scope
Eukaryota
Comments None

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.


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UniProtKB rule member sequences [?]