ProRule PRU01343

General rule information [?]

Accession PRU01343
Dates 18-MAY-2022 (Created)
19-NOV-2022 (Last updated, Version 2)
Data class Domain;
Predictors PROSITE; PS51999; ZF_GRF
Name Zinc finger GRF-type
Function GRF-ZFs are nucleic acid interaction modules and in several cases these motifs have been shown to enhance enzymatic activity.
Scope(s) Eukaryota
Example(s) Q6DCD7 (ZCHC4_XENLA);

Propagated annotation [?]

Keywords [?]

Gene Ontology [?]

case <FTGroup:1>
GO:0008270; Molecular function:zinc ion binding

Features [?]

From: PS51999
Key From To Description Tag Condition FTGroup
case <Feature:PS51999:1=[C]> and <Feature:PS51999:3=[HC]> and <Feature:PS51999:26=[C]> and <Feature:PS51999:38=[C]>
ZN_FING from to /note="GRF-type #"
else case <Feature:PS51999:1=[CH]> and <Feature:PS51999:3=[CH]> and <Feature:PS51999:26=[CH]> and <Feature:PS51999:38=[CH]>
ZN_FING from to /note="GRF-type #; atypical"
ZN_FING from to /note="GRF-type #; degenerate"
end case
BINDING 1 1 /ligand="Zn(2+)"
[CH] 1
BINDING 3 3 /ligand="Zn(2+)"
[CH] 1
BINDING 26 26 /ligand="Zn(2+)"
[CH] 1
BINDING 38 38 /ligand="Zn(2+)"
[CH] 1

Additional information [?]

Size range 35-65 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined


PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

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UniProtKB rule member sequences [?]