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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU01347


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU01347
General rule information [?]

Accession PRU01347
Dates 08-JUL-2022 (Created)
11-JUL-2022 (Last updated, Version 3)
Data class Domain;
Predictors PROSITE; PS52003; OCA
Name OCA domain
Function The 23 amino acid OCA domain binds to class II POU domain-containing transcription factors and a DNA octamer motif in a bivalent manner.
Scope(s) Eukaryota
Euteleostomi
Example(s) Q64693;

Propagated annotation [?]

Comments [?]

SUBCELLULAR LOCATIONNucleus.

Keywords [?]

Nucleus
Transcription
Transcription regulation
Activator

Gene Ontology [?]

GO:0005634; Cellular component:nucleus
GO:0006355; Biological process:regulation of DNA-templated transcription
GO:0006351; Biological process:DNA-templated transcription

Features [?]

From: PS52003
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="OCA #"

Additional information [?]

Size range 20-25 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]