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annotation rule: PRU01348

General rule information [?]

Accession PRU01348
Dates 11-AUG-2022 (Created)
11-AUG-2022 (Last updated, Version 1)
Data class Domain
Predictors PROSITE; PS52004; KS3_2
Name Ketosynthase family 3 (KS3) domain
Function Ketoacyl synthases (KSs) (more officially 3-oxoacyl synthases and also known as beta-ketoacyl synthases) are the condensing enzymes that catalyze the reaction of acyl-coenzyme A (acyl-CoA) or acyl-acyl carrier protein (acyl-ACP) with malonyl-CoA, malonyl-ACP, or occasionally other substrates.

Propagated annotation [?]


Cross-references [?]

case <FTGroup:1>
PROSITE PS00606; KS3_1; 1;

Gene Ontology [?]

GO:0006633; Biological process: fatty acid biosynthetic process.
GO:0004315; Molecular function: 3-oxoacyl-[acyl-carrier-protein] synthase activity.

Keywords [?]

Transferase
end case


Features [?]

From: PS52004
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       Ketosynthase family 3 (KS3) #        
ACT_SITE     171     171       For beta-ketoacyl synthase #1 activity     C   1
ACT_SITE     307     307       For beta-ketoacyl synthase #1 activity     H   1
ACT_SITE     347     347       For beta-ketoacyl synthase #1 activity     [HN]   1

Additional information [?]

Size range 240-550 amino acids
Related rules None
Repeats 1
Topology Undefined
Example P9WQE4 (PPSB_MYCTO)
Scope
Eukaryota
Bacteria
Comments None

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.


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UniProtKB rule member sequences [?]