ProRule PRU01348

General rule information [?]

Accession PRU01348
Dates 11-AUG-2022 (Created)
28-FEB-2023 (Last updated, Version 2)
Data class Domain;
Predictors PROSITE; PS52004; KS3_2
Name Ketosynthase family 3 (KS3) domain
Function Ketoacyl synthases (KSs) (more officially 3-oxoacyl synthases and also known as beta-ketoacyl synthases) are the condensing enzymes that catalyze the reaction of acyl-coenzyme A (acyl-CoA) or acyl-acyl carrier protein (acyl-ACP) with malonyl-CoA, malonyl-ACP, or occasionally other substrates.
Scope(s) Eukaryota
Example(s) P9WQE4 (PPSB_MYCTO);

Propagated annotation [?]

Keywords [?]

end case

Cross-references [?]

PROSITE PS00606; KS3_1; 1;

Features [?]

From: PS52004
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="Ketosynthase family 3 (KS3) #"
ACT_SITE 171 171 /note="For beta-ketoacyl synthase #1 activity" C 1
ACT_SITE 307 307 /note="For beta-ketoacyl synthase #1 activity" H 1
ACT_SITE 347 347 /note="For beta-ketoacyl synthase #1 activity" [HN] 1

Additional information [?]

Size range 240-550 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined


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UniProtKB rule member sequences [?]