PRU01359

General rule information [?]

Accession	PRU01359
Dates	27-JAN-2023 (Created) 27-JAN-2023 (Last updated, Version 1)

Data class

Domain

Predictors

PROSITE; PS52015; TONB_CTD

Name	TonB C-terminal domain

Function

The TonB protein plays an essential role in the energy transduction system to drive active transport across the outer membrane (OM) using the proton-motive force of the cytoplasmic membrane of Gram-negative bacteria. The C-terminal domain (CTD) of TonB protein is known to interact with the conserved TonB box motif of TonB-dependent OM transporters, which likely induces structural changes in the OM transporters.

Propagated annotation [?]

Comments [?]

Subcellular location	Cell inner membrane; Single-pass membrane protein; Periplasmic side.
Similarity	Belongs to the TonB family.

Gene Ontology [?]

GO:0055085; Biological process: transmembrane transport.
GO:0015031; Biological process: protein transport.
GO:0031992; Molecular function: energy transducer activity.
GO:0030288; Cellular component: outer membrane-bounded periplasmic space.

Keywords [?]

Cell inner membrane
Cell membrane
Membrane
Protein transport
Transmembrane
Transmembrane helix
Transport

Features [?]

From: PS52015

Key From To Description Tag Condition FTGroup

DOMAIN from to TonB C-terminal #

Additional information [?]

Size range	85-95 amino acids
Related rules	None
Repeats	1
Topology	Undefined
Example	O52042 (TONB_VIBCH)
Scope	Bacteria; Pseudomonadota
Comments	None

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

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UniProtKB rule member sequences [?]

UniProtKB/Swiss-Prot sets

Bacteria [22]
Retrieve set of proteins with 3D structure for this domain