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General rule information [?]

Accession PRU01359
Dates 27-JAN-2023 (Created)
27-JAN-2023 (Last updated, Version 1)
Data class Domain
Predictors PROSITE; PS52015; TONB_CTD
Name TonB C-terminal domain
Function The TonB protein plays an essential role in the energy transduction system to drive active transport across the outer membrane (OM) using the proton-motive force of the cytoplasmic membrane of Gram-negative bacteria. The C-terminal domain (CTD) of TonB protein is known to interact with the conserved TonB box motif of TonB-dependent OM transporters, which likely induces structural changes in the OM transporters.

Propagated annotation [?]

Comments [?]

Subcellular location Cell inner membrane; Single-pass membrane protein; Periplasmic side.
Similarity Belongs to the TonB family.

Gene Ontology [?]

GO:0055085; Biological process: transmembrane transport.
GO:0015031; Biological process: protein transport.
GO:0031992; Molecular function: energy transducer activity.
GO:0030288; Cellular component: outer membrane-bounded periplasmic space.

Keywords [?]

Features [?]

From: PS52015
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       TonB C-terminal #        

Additional information [?]

Size range 85-95 amino acids
Related rules None
Repeats 1
Topology Undefined
Example O52042 (TONB_VIBCH)
Bacteria; Pseudomonadota
Comments None


PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]