ProRule PRU01359

General rule information [?]

Accession PRU01359
Dates 27-JAN-2023 (Created)
-- (Last updated, Version 1)
Data class Domain;
Predictors PROSITE; PS52015; TONB_CTD
Name TonB C-terminal domain
Function The TonB protein plays an essential role in the energy transduction system to drive active transport across the outer membrane (OM) using the proton-motive force of the cytoplasmic membrane of Gram-negative bacteria. The C-terminal domain (CTD) of TonB protein is known to interact with the conserved TonB box motif of TonB-dependent OM transporters, which likely induces structural changes in the OM transporters.
Scope(s) Bacteria
Example(s) O52042 (TONB_VIBCH);

Propagated annotation [?]

Comments [?]

SUBCELLULAR LOCATIONCell inner membrane; Single-pass membrane protein; Periplasmic side.
SIMILARITYBelongs to the TonB family.

Keywords [?]

Gene Ontology [?]

GO:0055085; Biological process:transmembrane transport
GO:0015031; Biological process:protein transport
GO:0031992; Molecular function:energy transducer activity
GO:0030288; Cellular component:outer membrane-bounded periplasmic space

Features [?]

From: PS52015
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="TonB C-terminal #"

Additional information [?]

Size range 85-95 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined


PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

View rule in raw text format (no links)

UniProtKB rule member sequences [?]