ProRule PRU01371

General rule information [?]

Accession PRU01371
Dates 2-JUN-2023 (Created)
-- (Last updated, Version 1)
Data class Domain;
Predictors PROSITE; PS52027; ZF_C2HC_C3H
Name Zinc finger C2HC/C3H-type
Function The C2HC/C3H-type zinc finger has first been identified in four copies in Zfp474, a protein exclusively found in testis and ovary and thought to function as a germ cell specific transcription factor that plays important roles in spermatid differentiation and oocyte development.
Scope(s) Eukaryota
Example(s) Q6V5K9 (ZN474_MOUSE);

Propagated annotation [?]

Comments [?]

case (<Feature:PS52027:5=[CH]> and <Feature:PS52027:8=[CH]> and <Feature:PS52027:20=[HC]> and <Feature:PS52027:24=[CH]>)
COFACTORName=Zn(2+); Xref=ChEBI:CHEBI:29105;

Keywords [?]

Gene Ontology [?]

GO:0008270; Molecular function:zinc ion binding
GO:0046872; Molecular function:metal ion binding

Features [?]

From: PS52027
Key From To Description Tag Condition FTGroup
case (<Feature:PS52027:5=C> and <Feature:PS52027:8=C> and <Feature:PS52027:20=H> and <Feature:PS52027:24=C>)
ZN_FING from to /note="C2HC/C3H-type #"
else case (<Feature:PS52027:5=[CH]> and <Feature:PS52027:8=[CH]> and <Feature:PS52027:20=[HC]> and <Feature:PS52027:24=[CH]>)
ZN_FING from to /note="C2HC/C3H-type #; atypical"
ZN_FING from to /note="C2HC/C3H-type #; degenerate"
end case
BINDING 5 5 /ligand="Zn(2+)"
[CH] 1
BINDING 8 8 /ligand="Zn(2+)"
[CH] 1
BINDING 20 20 /ligand="Zn(2+)"
[CH] 1
BINDING 24 24 /ligand="Zn(2+)"
[CH] 1

Additional information [?]

Size range 25-35 amino acids
Related rules None
Fusion None
Repeats 1-6
Topology Undefined


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UniProtKB rule member sequences [?]