PROSITE entry PS52027
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General information about the entry
| PURL [info] | https://purl.expasy.org/prosite/signature/PS52027 |
| Entry name [info] | ZF_C2HC_C3H |
| Accession [info] | PS52027 |
| Entry type [info] | MATRIX |
| Date [info] |
13-SEP-2023 CREATED;
13-SEP-2023 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC52027 |
| Associated ProRule [info] | PRU01371 |
Name and characterization of the entry
| Description [info] | Zinc finger C2HC/C3H-type profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=30; /DISJOINT: DEFINITION=PROTECT; N1=4; N2=27; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.3153749; R2=0.0096202; TEXT='-LogE'; /CUT_OFF: LEVEL=0; SCORE=1267; N_SCORE=14.5; MODE=1; TEXT='R'; /CUT_OFF: LEVEL=-1; SCORE=435; N_SCORE=6.5; MODE=1; TEXT='R?'; /DEFAULT: M0=-41; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255; ... A C D E F G H I K L M N P Q R S T V W Y /I: B1=0; BI=-255; BD=-255; /M: SY='Q'; M= -38,-124, 42, 22,-126, 10, -19, -55, -8, -48,-113, 22, 51, 51, -7, 13, -4, -49,-129,-116; /M: SY='L'; M= -37, -27,-119, -79, 11,-123, -55, -93, -44, 62, 33, -45, -15, -19, 19, -23, 37, -50, -23, 24; /M: SY='V'; M= -13,-119, -60, 11, 14, -31, -31, 35, -27, 5, -18, -74, -7, -12, -33, -33, -48, 59,-120, 1; /M: SY='P'; M= -22, -41,-106, 25,-123, -65, -48, -10, -15, -39,-108, -42, 82, 65, 19, -14, -4, -20,-125,-116; /M: SY='C'; M=-109, 157,-127,-127, -46,-124,-127,-125,-121,-116,-116,-114, -64,-129, -28, -48,-108,-114,-145,-127; /M: SY='P'; M= -15,-125, 4, 24,-113, -45, -1, -34, 15, -93,-111, 13, 66, 8, 3, 19, -4,-116,-117, 50; /M: SY='H'; M=-109,-120, -52,-113, -10, -78, 68, 49, -13, 5, -95, 38,-121, -16, -74, -8, 9, 19,-118, 45; /I: I=-30; MI=0; MD=-77; IM=0; DM=-77; /M: SY='C'; M=-109, 157,-126, -49,-118,-124,-126,-126,-121,-116,-116,-114,-138,-128, -28,-111,-109,-114,-144, -31; /M: SY='G'; M= -46,-123, -18, -24,-128, 84, 14, -83, 1,-128, -48, 14, -25, 19, -35, 20,-107,-125,-125,-118; /M: SY='R'; M= -41,-129,-110, -65,-123,-123, 8, -66, 5, -76,-110,-103,-121, 17, 115,-107,-112,-121,-123,-109; /M: SY='T'; M= -81, 14, -44, -4, -71, -53, 25, -82, 52, -62, -26, 30, -47, 8, 40, -6, 58, -71, -24, -33; /M: SY='F'; M=-121,-119,-131, -32, 123,-130,-113, -51,-124, -38, -37,-123,-132,-131,-122, -82,-114, -45, -90, 17; /M: SY='N'; M= 47,-116, -49,-111, 21, 12, -29, 0, -2, 3,-102, 50,-119, -35, -31, -29, 2, -4, -18,-107; /M: SY='P'; M= 15, -64, -17, 33,-124, -72, -63, -56, -12, -44, -51, -47, 84, 19, -5, 17, -12, -9,-127,-118; /M: SY='D'; M= 1,-122, 79, 32, -65, -83, -1, -73, 12, -77, -26, -2,-113, 15, 4, 9, 10, -59, -14,-113; /M: SY='R'; M= 34, -52, -18,-104,-119,-110, -44, -42, -51,-114,-109,-102,-118, -98, 79, 59, -34, 22,-127,-112; /M: SY='L'; M= 18,-117,-129,-123, 21, -89,-118, 46,-122, 72, -34,-125,-127,-118, -75,-117,-108, -10,-115, -15; /M: SY='E'; M= 7,-123, 28, 62, -64, -32, -40, -86, 10, -9, -31, 4, 21, 44, -75, -22, -27, -23,-126, -56; /M: SY='R'; M= -10,-123,-112, -20, -1,-122, -53, 28, 61, -50, -46,-107,-118, -3, 65,-107, -18, 24,-121,-107; /M: SY='H'; M= -65,-128,-101,-101,-116,-118, 154,-132, -71,-116,-102, -48, -53, -29,-100,-105, -58,-132,-149, -86; /M: SY='E'; M= -12,-123,-101, 66,-116, -57, -44, 34, -26, -44, 19, -40,-113, 64, -36, -23, 0, 15,-125,-112; /M: SY='P'; M= -10,-126, -18, 10,-126, -51, -54,-121, 53, -82,-113, -6, 68, -4, 56, -10, -25, -38,-126,-116; /M: SY='I'; M= -1, -32,-115, -28, 8, -69, -3, 61, 20, -51, -97, -30, -67, 34, -39, 20, -33, 26, 11, -60; /M: SY='C'; M= -69, 155, -80,-126,-119,-124,-126, -66,-120, -78,-115,-114, -44,-128, -16, -75,-108,-113,-146,-128; /M: SY='K'; M= -3,-122,-105, 16, -70, -34, 2, -10, 59, -7, -1, -28, -51, 37, 38, -11, 2, -65,-122, -31; /M: SY='K'; M= 14,-122, -18, 27,-124, -17, -27,-119, 73,-120, -28, -2, -10, 7, 10, -25, 7, -22, -9,-114; /M: SY='Q'; M= -13,-121, -39, -44, -31, -49, -52, 6, 34, -22, 33, -17, -33, 49, 35, -6, 7, 23, 2, -63; /M: SY='W'; M= 5,-123, -49, -75, 22, -38, 43, -52, 35, -68, -14, 1, 22, 33, 6, 9, -17, -21, 87, -36; /M: SY='Q'; M= 22,-120, -8, -32, -69, -23, 6, -51, 33, -23, -54, 32, 11, 46, -12, 30, 2, -54,-125, -24; /M: SY='K'; M= -9, -65, -41, -11, -15, 7, 2, -55, 64, -58, -44, -5, -27, 4, 48, -1, -5, -24,-123,-110; /I: E1=0; IE=-255; DE=-255;» more |
Numerical results [info]
| Total number of hits | 52 in 23 different sequences |
| Number of true positive hits | 52 in 23 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 0 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 100.00 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 6 |
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | CJA_Sigrist |
| Feature key [info] | ZN_FING |
| Feature description [info] | C2HC/C3H-type |
| Version [info] | 1 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
23 sequences
SOK1_PHYPA (A0A2K1JJ00), SOK3_PHYPA (A0A2K1J5A5), SOK_MARPO (A0A2R6X6S3), ZC21A_BOVIN (A4FUE7), ZC21A_CAEBR (Q618K0), ZC21A_CAEEL (Q22122), ZC21A_DANRE (Q7SXT7), ZC21A_HUMAN (Q96GY0), ZC21A_MOUSE (Q8BJH1), ZC21A_PONAB (Q5REC0), ZC21A_XENLA (Q5PPV5), ZC21B_BOVIN (Q32KN7), ZC21B_HUMAN (Q5TFG8), ZC21B_MOUSE (Q9D534), ZC21C_HUMAN (Q53FD0), ZC21C_MACFA (Q9BGW4), ZC21C_MOUSE (Q8CCG1), ZC21C_RAT (Q6AYP4), ZN474_BOVIN (A6QQM4), ZN474_HUMAN (Q6S9Z5), ZN474_MACFA (Q4R8T4), ZN474_MOUSE (Q6V5K9), ZN475_HUMAN (A0A1B0GTH9)» more
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