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PROSITE entry PS52027


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General information about the entry

Entry name [info] ZF_C2HC_C3H
Accession [info] PS52027
Entry type [info] MATRIX
Date [info] 13-SEP-2023 CREATED;
13-SEP-2023 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC52027
Associated ProRule [info] PRU01371

Name and characterization of the entry

Description [info] Zinc finger C2HC/C3H-type profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=30;
/DISJOINT: DEFINITION=PROTECT; N1=4; N2=27;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.3153749; R2=0.0096202; TEXT='-LogE';
/CUT_OFF: LEVEL=0; SCORE=1267; N_SCORE=14.5; MODE=1; TEXT='R';
/CUT_OFF: LEVEL=-1; SCORE=435; N_SCORE=6.5; MODE=1; TEXT='R?';
/DEFAULT: M0=-41; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255;
...
                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-255; BD=-255;
/M: SY='Q';  M= -38,-124,  42,  22,-126,  10, -19, -55,  -8, -48,-113,  22,  51,  51,  -7,  13,  -4, -49,-129,-116;
/M: SY='L';  M= -37, -27,-119, -79,  11,-123, -55, -93, -44,  62,  33, -45, -15, -19,  19, -23,  37, -50, -23,  24;
/M: SY='V';  M= -13,-119, -60,  11,  14, -31, -31,  35, -27,   5, -18, -74,  -7, -12, -33, -33, -48,  59,-120,   1;
/M: SY='P';  M= -22, -41,-106,  25,-123, -65, -48, -10, -15, -39,-108, -42,  82,  65,  19, -14,  -4, -20,-125,-116;
/M: SY='C';  M=-109, 157,-127,-127, -46,-124,-127,-125,-121,-116,-116,-114, -64,-129, -28, -48,-108,-114,-145,-127;
/M: SY='P';  M= -15,-125,   4,  24,-113, -45,  -1, -34,  15, -93,-111,  13,  66,   8,   3,  19,  -4,-116,-117,  50;
/M: SY='H';  M=-109,-120, -52,-113, -10, -78,  68,  49, -13,   5, -95,  38,-121, -16, -74,  -8,   9,  19,-118,  45;
/I:         I=-30; MI=0; MD=-77; IM=0; DM=-77;
/M: SY='C';  M=-109, 157,-126, -49,-118,-124,-126,-126,-121,-116,-116,-114,-138,-128, -28,-111,-109,-114,-144, -31;
/M: SY='G';  M= -46,-123, -18, -24,-128,  84,  14, -83,   1,-128, -48,  14, -25,  19, -35,  20,-107,-125,-125,-118;
/M: SY='R';  M= -41,-129,-110, -65,-123,-123,   8, -66,   5, -76,-110,-103,-121,  17, 115,-107,-112,-121,-123,-109;
/M: SY='T';  M= -81,  14, -44,  -4, -71, -53,  25, -82,  52, -62, -26,  30, -47,   8,  40,  -6,  58, -71, -24, -33;
/M: SY='F';  M=-121,-119,-131, -32, 123,-130,-113, -51,-124, -38, -37,-123,-132,-131,-122, -82,-114, -45, -90,  17;
/M: SY='N';  M=  47,-116, -49,-111,  21,  12, -29,   0,  -2,   3,-102,  50,-119, -35, -31, -29,   2,  -4, -18,-107;
/M: SY='P';  M=  15, -64, -17,  33,-124, -72, -63, -56, -12, -44, -51, -47,  84,  19,  -5,  17, -12,  -9,-127,-118;
/M: SY='D';  M=   1,-122,  79,  32, -65, -83,  -1, -73,  12, -77, -26,  -2,-113,  15,   4,   9,  10, -59, -14,-113;
/M: SY='R';  M=  34, -52, -18,-104,-119,-110, -44, -42, -51,-114,-109,-102,-118, -98,  79,  59, -34,  22,-127,-112;
/M: SY='L';  M=  18,-117,-129,-123,  21, -89,-118,  46,-122,  72, -34,-125,-127,-118, -75,-117,-108, -10,-115, -15;
/M: SY='E';  M=   7,-123,  28,  62, -64, -32, -40, -86,  10,  -9, -31,   4,  21,  44, -75, -22, -27, -23,-126, -56;
/M: SY='R';  M= -10,-123,-112, -20,  -1,-122, -53,  28,  61, -50, -46,-107,-118,  -3,  65,-107, -18,  24,-121,-107;
/M: SY='H';  M= -65,-128,-101,-101,-116,-118, 154,-132, -71,-116,-102, -48, -53, -29,-100,-105, -58,-132,-149, -86;
/M: SY='E';  M= -12,-123,-101,  66,-116, -57, -44,  34, -26, -44,  19, -40,-113,  64, -36, -23,   0,  15,-125,-112;
/M: SY='P';  M= -10,-126, -18,  10,-126, -51, -54,-121,  53, -82,-113,  -6,  68,  -4,  56, -10, -25, -38,-126,-116;
/M: SY='I';  M=  -1, -32,-115, -28,   8, -69,  -3,  61,  20, -51, -97, -30, -67,  34, -39,  20, -33,  26,  11, -60;
/M: SY='C';  M= -69, 155, -80,-126,-119,-124,-126, -66,-120, -78,-115,-114, -44,-128, -16, -75,-108,-113,-146,-128;
/M: SY='K';  M=  -3,-122,-105,  16, -70, -34,   2, -10,  59,  -7,  -1, -28, -51,  37,  38, -11,   2, -65,-122, -31;
/M: SY='K';  M=  14,-122, -18,  27,-124, -17, -27,-119,  73,-120, -28,  -2, -10,   7,  10, -25,   7, -22,  -9,-114;
/M: SY='Q';  M= -13,-121, -39, -44, -31, -49, -52,   6,  34, -22,  33, -17, -33,  49,  35,  -6,   7,  23,   2, -63;
/M: SY='W';  M=   5,-123, -49, -75,  22, -38,  43, -52,  35, -68, -14,   1,  22,  33,   6,   9, -17, -21,  87, -36;
/M: SY='Q';  M=  22,-120,  -8, -32, -69, -23,   6, -51,  33, -23, -54,  32,  11,  46, -12,  30,   2, -54,-125, -24;
/M: SY='K';  M=  -9, -65, -41, -11, -15,   7,   2, -55,  64, -58, -44,  -5, -27,   4,  48,  -1,  -5, -24,-123,-110;
/I:         E1=0; IE=-255; DE=-255;
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_03 which contains 571'609 sequence entries.


Total number of hits 52 in 23 different sequences
Number of true positive hits 52 in 23 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 6
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] ZN_FING
Feature description [info] C2HC/C3H-type
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
23 sequences

SOK1_PHYPA  (A0A2K1JJ00), SOK3_PHYPA  (A0A2K1J5A5), SOK_MARPO   (A0A2R6X6S3), 
ZC21A_BOVIN (A4FUE7), ZC21A_CAEBR (Q618K0), ZC21A_CAEEL (Q22122), 
ZC21A_DANRE (Q7SXT7), ZC21A_HUMAN (Q96GY0), ZC21A_MOUSE (Q8BJH1), 
ZC21A_PONAB (Q5REC0), ZC21A_XENLA (Q5PPV5), ZC21B_BOVIN (Q32KN7), 
ZC21B_HUMAN (Q5TFG8), ZC21B_MOUSE (Q9D534), ZC21C_HUMAN (Q53FD0), 
ZC21C_MACFA (Q9BGW4), ZC21C_MOUSE (Q8CCG1), ZC21C_RAT   (Q6AYP4), 
ZN474_BOVIN (A6QQM4), ZN474_HUMAN (Q6S9Z5), ZN474_MACFA (Q4R8T4), 
ZN474_MOUSE (Q6V5K9), ZN475_HUMAN (A0A1B0GTH9)
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