ProRule PRU01372

General rule information [?]

Accession PRU01372
Dates 29-JUN-2023 (Created)
-- (Last updated, Version 1)
Data class Domain;
Predictors PROSITE; PS52028; SMCR
Name Streptococcal M proteins C repeat
Function M proteins belong to a family of fibrous streptococcal surface proteins which represent major virulence factors due to their antiphagocytic activities. The C repeats are present in all M proteins, although the number of repeat sequences varies from two (M6) to four (M12). The conserved repetitive C units are responsible for several biological activities of M and M-like proteins.
Scope(s) Bacteria
Example(s) P16947 (M49_STRP9);

Propagated annotation [?]

Comments [?]

SUBCELLULAR LOCATIONSecreted, cell wall; Peptidoglycan-anchor.
SIMILARITYBelongs to the M protein family.

Keywords [?]

Gene Ontology [?]

GO:0005576; Cellular component:extracellular region

Features [?]

From: PS52028
Key From To Description Tag Condition FTGroup
REPEAT from to /note="C #"

Additional information [?]

Size range 35-36 amino acids
Related rules None
Fusion None
Repeats 2-4
Topology Undefined


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UniProtKB rule member sequences [?]