PROSITE entry PS52028
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General information about the entry
| PURL [info] | https://purl.expasy.org/prosite/signature/PS52028 |
| Entry name [info] | SMCR |
| Accession [info] | PS52028 |
| Entry type [info] | MATRIX |
| Date [info] |
08-NOV-2023 CREATED;
08-NOV-2023 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC52028 |
| Associated ProRule [info] | PRU01372 |
Name and characterization of the entry
| Description [info] | Streptococcal M proteins C repeat profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=35; /DISJOINT: DEFINITION=PROTECT; N1=4; N2=32; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.3615907; R2=0.0137048; TEXT='-LogE'; /CUT_OFF: LEVEL=0; SCORE=594; N_SCORE=9.5; MODE=1; TEXT='R'; /CUT_OFF: LEVEL=-1; SCORE=375; N_SCORE=6.5; MODE=1; TEXT='R?'; /DEFAULT: M0=-7; D=-20; I=-20; B1=-100; E1=-100; MI=-105; MD=-105; IM=-105; DM=-105; ... A B C D E F G H I K L M N P Q R S T V W Y Z /I: B1=0; BI=-105; BD=-105; /M: SY='D'; M= 7, 14,-23, 17, 13,-32,-10, -4,-24, 0,-20,-15, 3, -9, 13, -8, 3, -7,-20,-27,-18, 13; /M: SY='K'; M= -6, 3,-28, 4, 9,-30,-18,-10,-29, 41,-28,-12, 1,-10, 8, 23, -8, -9,-19,-22,-12, 8; /M: SY='L'; M= -6,-26,-16,-27,-21, 2,-29,-23, 19,-20, 26, 12,-26,-28,-21,-16,-18, -3, 23,-24, -5,-21; /M: SY='E'; M= -9, 6,-26, 10, 17,-25,-21,-10,-19, 14,-19,-12, -1,-10, 4, 4, -3, -2,-13,-28,-13, 10; /I: I=-6; MI=0; MD=-32; IM=0; DM=-32; /M: SY='E'; M=-12, 15,-29, 23, 44,-30,-18, 0,-31, 12,-23,-20, 6, -5, 15, 6, -1, -9,-29,-31,-19, 29; /M: SY='E'; M=-12, 8,-29, 15, 31,-30,-13, 0,-27, 6,-18,-14, 1, -8, 20, 4, -3,-11,-27,-27,-17, 25; /M: SY='N'; M= -9, 9,-25, 1, -1,-21,-14, 0,-14, 9,-22,-10, 19,-10, 0, 3, 0, -5,-17,-30,-12, -2; /M: SY='Q'; M= -5, -4,-29, -3, 12,-30,-19, -4,-21, 19,-19, -6, -4, -3, 24, 10, -5, -9,-22,-21,-12, 18; /M: SY='I'; M= -6,-28,-22,-34,-28, 3,-33,-28, 36,-26, 13, 13,-20,-23,-22,-25,-12, -5, 31,-23, -3,-28; /M: SY='S'; M= 1, -9,-16, -9, -3,-14,-12,-10, -8,-13, -4, -5, -4,-16, 2,-10, 13, 7, -7,-31,-13, 0; /M: SY='D'; M=-13, 22,-28, 30, 30,-30,-15, -2,-31, 9,-24,-21, 11, -7, 9, 3, 1, -4,-26,-32,-18, 19; /M: SY='A'; M= 30,-10,-15,-16, -3,-20, -7,-16,-10, -9, -8, -8,-10, -5, -3,-16, 5, 0, -5,-22,-18, -4; /M: SY='S'; M= 7, 1,-14, -1, -1,-20, -3, -8,-21, -4,-27,-18, 11,-12, 1, 1, 28, 13,-12,-36,-19, -1; /M: SY='R'; M=-18,-11,-28,-11, -2,-18,-21, 5,-25, 23,-18, -8, -2,-21, 7, 57,-10,-10,-15,-22, -8, -2; /M: SY='Q'; M= -9, -2,-28, -3, 10,-30,-21, -4,-21, 24,-19, -4, -2,-11, 26, 16, -5, -5,-20,-21, -9, 18; /M: SY='G'; M= -1,-11,-27,-11,-18,-26, 49,-18,-32,-15,-26,-17, -2,-20,-17,-12, 2,-14,-21,-22,-26,-18; /M: SY='L'; M= -9,-26,-18,-28,-20, 12,-29,-21, 15,-26, 35, 13,-25,-27,-21,-19,-20, 0, 11,-20, 0,-20; /M: SY='R'; M= 5, -2,-18, -6, -2,-20, -8, -7,-22, 6,-22,-14, 6,-15, 2, 19, 12, 3,-13,-28,-16, -2; /M: SY='R'; M=-17,-11,-28,-11, -2,-19,-19, -3,-26, 24,-19, -9, -1,-20, 7, 59, -7, -8,-15,-22,-11, -2; /M: SY='D'; M= -5, 32,-25, 43, 10,-34, -3, -6,-33, -4,-25,-25, 12,-11, -4,-12, 3, -5,-23,-34,-20, 3; /M: SY='L'; M=-12,-32,-25,-32,-22, 16,-28,-22, 12,-28, 35, 12,-31,-30,-22,-20,-31,-13, 2, 11, 7,-21; /M: SY='E'; M=-11, 19,-27, 28, 33,-29,-17, -4,-29, 6,-22,-21, 6, -5, 9, -3, 3, 0,-24,-32,-18, 21; /I: I=-6; MD=-32; /M: SY='A'; M= 36, -8,-11,-15, -8,-17, -2, -5,-11, -9,-10, -8, -7,-10, -7,-15, 7, -2, -3,-18,-13, -8; D=-6; /I: I=-6; MI=-32; IM=-32; DM=-32; /M: SY='S'; M= 9, -6,-14, -9, -6,-16, -9, -3,-13, -9,-15,-10, 0,-14, -4, -7, 17, 10, -5,-32,-13, -6; /M: SY='R'; M=-17,-12,-27,-12, -3,-18,-22, -3,-20, 20,-12, -5, -5,-21, 8, 50,-11, -9,-12,-21, -9, -1; /M: SY='E'; M= -3, 10,-28, 16, 28,-30,-10, -6,-30, 14,-23,-18, 2, -6, 8, 2, -1, -9,-24,-27,-18, 18; /M: SY='A'; M= 19, -8,-16,-11, -7,-16,-10,-17, -8, -9, -5, -7,-10, -9,-10,-15, 3, -1, -2,-25,-16, -9; /M: SY='K'; M= -9, 3,-25, -1, 2,-21,-16, -6,-21, 23,-19, -9, 8,-16, 3, 19, -5, -6,-17,-25,-11, 2; /M: SY='K'; M=-10, 5,-28, 4, 15,-28,-18, -5,-27, 31,-26,-12, 6,-10, 13, 21, -4, -5,-22,-24,-12, 14; /M: SY='K'; M= -2, -1,-25, -3, 7,-25,-16, 8,-21, 15,-18, -6, 2,-13, 12, 8, -5, -9,-19,-23, -8, 9; /M: SY='V'; M= 0,-19,-16,-20,-12, -7,-25,-19, 11,-15, 10, 6,-20,-22, -9,-14, -9, 0, 17,-26, -9,-11; /M: SY='E'; M= -7, -1,-26, 3, 22,-23,-10,-10,-22, 6,-15,-12, -4, -9, 4, -1, -2, -4,-17,-26,-16, 13; /M: SY='A'; M= 22, -1,-15, -6, 2,-21, 0,-13,-18, -7,-18,-15, 1,-10, -4,-13, 15, 5,-10,-28,-20, -1; /M: SY='E'; M= -5, 11,-26, 17, 25,-28,-16, -5,-24, 6,-15,-14, 0, -8, 9, -2, -3, -9,-21,-28,-16, 17; /M: SY='L'; M= -7,-17,-22,-18, -7, -5,-25, -2, 3,-15, 18, 7,-15,-21, -9,-12,-16, -7, -1,-23, -2, -9; /I: E1=0; IE=-105; DE=-105;» more |
Numerical results [info]
| Total number of hits | 37 in 12 different sequences |
| Number of true positive hits | 37 in 12 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 0 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 100.00 % |
Comments [info]
| Taxonomic range [info] | Prokaryotes (Bacteria) |
| Maximum number of repetitions [info] | 4 |
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | CJA_Sigrist |
| Feature key [info] | REPEAT |
| Feature description [info] | C |
| Version [info] | 1 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
12 sequences
ARP4_STRPY (P13050), M12_STRPY (P19401), M21_STRPY (P50468), M22_STRPY (P50469), M24_STRPY (P12379), M49_STRP9 (P16947), M5_STRP5(P02977), M6A_STRP6 (Q5X9Q9), M6B_STRPY (P08089), MX_STRP9(P16946), PAM_STRPY (P49054), SPH_STRP1 (P50470)» more
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| PDB [Detailed view] |
3 PDB
2KK9; 8SKV; 8TVL |