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PROSITE entry PS52028


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General information about the entry

Entry name [info] SMCR
Accession [info] PS52028
Entry type [info] MATRIX
Date [info] 08-NOV-2023 CREATED;
08-NOV-2023 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC52028
Associated ProRule [info] PRU01372

Name and characterization of the entry

Description [info] Streptococcal M proteins C repeat profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=35;
/DISJOINT: DEFINITION=PROTECT; N1=4; N2=32;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.3615907; R2=0.0137048; TEXT='-LogE';
/CUT_OFF: LEVEL=0; SCORE=594; N_SCORE=9.5; MODE=1; TEXT='R';
/CUT_OFF: LEVEL=-1; SCORE=375; N_SCORE=6.5; MODE=1; TEXT='R?';
/DEFAULT: M0=-7; D=-20; I=-20; B1=-100; E1=-100; MI=-105; MD=-105; IM=-105; DM=-105;
...
                A   B   C   D   E   F   G   H   I   K   L   M   N   P   Q   R   S   T   V   W   Y   Z
/I:         B1=0; BI=-105; BD=-105;
/M: SY='D';  M=  7, 14,-23, 17, 13,-32,-10, -4,-24,  0,-20,-15,  3, -9, 13, -8,  3, -7,-20,-27,-18, 13;
/M: SY='K';  M= -6,  3,-28,  4,  9,-30,-18,-10,-29, 41,-28,-12,  1,-10,  8, 23, -8, -9,-19,-22,-12,  8;
/M: SY='L';  M= -6,-26,-16,-27,-21,  2,-29,-23, 19,-20, 26, 12,-26,-28,-21,-16,-18, -3, 23,-24, -5,-21;
/M: SY='E';  M= -9,  6,-26, 10, 17,-25,-21,-10,-19, 14,-19,-12, -1,-10,  4,  4, -3, -2,-13,-28,-13, 10;
/I:         I=-6; MI=0; MD=-32; IM=0; DM=-32;
/M: SY='E';  M=-12, 15,-29, 23, 44,-30,-18,  0,-31, 12,-23,-20,  6, -5, 15,  6, -1, -9,-29,-31,-19, 29;
/M: SY='E';  M=-12,  8,-29, 15, 31,-30,-13,  0,-27,  6,-18,-14,  1, -8, 20,  4, -3,-11,-27,-27,-17, 25;
/M: SY='N';  M= -9,  9,-25,  1, -1,-21,-14,  0,-14,  9,-22,-10, 19,-10,  0,  3,  0, -5,-17,-30,-12, -2;
/M: SY='Q';  M= -5, -4,-29, -3, 12,-30,-19, -4,-21, 19,-19, -6, -4, -3, 24, 10, -5, -9,-22,-21,-12, 18;
/M: SY='I';  M= -6,-28,-22,-34,-28,  3,-33,-28, 36,-26, 13, 13,-20,-23,-22,-25,-12, -5, 31,-23, -3,-28;
/M: SY='S';  M=  1, -9,-16, -9, -3,-14,-12,-10, -8,-13, -4, -5, -4,-16,  2,-10, 13,  7, -7,-31,-13,  0;
/M: SY='D';  M=-13, 22,-28, 30, 30,-30,-15, -2,-31,  9,-24,-21, 11, -7,  9,  3,  1, -4,-26,-32,-18, 19;
/M: SY='A';  M= 30,-10,-15,-16, -3,-20, -7,-16,-10, -9, -8, -8,-10, -5, -3,-16,  5,  0, -5,-22,-18, -4;
/M: SY='S';  M=  7,  1,-14, -1, -1,-20, -3, -8,-21, -4,-27,-18, 11,-12,  1,  1, 28, 13,-12,-36,-19, -1;
/M: SY='R';  M=-18,-11,-28,-11, -2,-18,-21,  5,-25, 23,-18, -8, -2,-21,  7, 57,-10,-10,-15,-22, -8, -2;
/M: SY='Q';  M= -9, -2,-28, -3, 10,-30,-21, -4,-21, 24,-19, -4, -2,-11, 26, 16, -5, -5,-20,-21, -9, 18;
/M: SY='G';  M= -1,-11,-27,-11,-18,-26, 49,-18,-32,-15,-26,-17, -2,-20,-17,-12,  2,-14,-21,-22,-26,-18;
/M: SY='L';  M= -9,-26,-18,-28,-20, 12,-29,-21, 15,-26, 35, 13,-25,-27,-21,-19,-20,  0, 11,-20,  0,-20;
/M: SY='R';  M=  5, -2,-18, -6, -2,-20, -8, -7,-22,  6,-22,-14,  6,-15,  2, 19, 12,  3,-13,-28,-16, -2;
/M: SY='R';  M=-17,-11,-28,-11, -2,-19,-19, -3,-26, 24,-19, -9, -1,-20,  7, 59, -7, -8,-15,-22,-11, -2;
/M: SY='D';  M= -5, 32,-25, 43, 10,-34, -3, -6,-33, -4,-25,-25, 12,-11, -4,-12,  3, -5,-23,-34,-20,  3;
/M: SY='L';  M=-12,-32,-25,-32,-22, 16,-28,-22, 12,-28, 35, 12,-31,-30,-22,-20,-31,-13,  2, 11,  7,-21;
/M: SY='E';  M=-11, 19,-27, 28, 33,-29,-17, -4,-29,  6,-22,-21,  6, -5,  9, -3,  3,  0,-24,-32,-18, 21;
/I:         I=-6; MD=-32;
/M: SY='A';  M= 36, -8,-11,-15, -8,-17, -2, -5,-11, -9,-10, -8, -7,-10, -7,-15,  7, -2, -3,-18,-13, -8; D=-6;
/I:         I=-6; MI=-32; IM=-32; DM=-32;
/M: SY='S';  M=  9, -6,-14, -9, -6,-16, -9, -3,-13, -9,-15,-10,  0,-14, -4, -7, 17, 10, -5,-32,-13, -6;
/M: SY='R';  M=-17,-12,-27,-12, -3,-18,-22, -3,-20, 20,-12, -5, -5,-21,  8, 50,-11, -9,-12,-21, -9, -1;
/M: SY='E';  M= -3, 10,-28, 16, 28,-30,-10, -6,-30, 14,-23,-18,  2, -6,  8,  2, -1, -9,-24,-27,-18, 18;
/M: SY='A';  M= 19, -8,-16,-11, -7,-16,-10,-17, -8, -9, -5, -7,-10, -9,-10,-15,  3, -1, -2,-25,-16, -9;
/M: SY='K';  M= -9,  3,-25, -1,  2,-21,-16, -6,-21, 23,-19, -9,  8,-16,  3, 19, -5, -6,-17,-25,-11,  2;
/M: SY='K';  M=-10,  5,-28,  4, 15,-28,-18, -5,-27, 31,-26,-12,  6,-10, 13, 21, -4, -5,-22,-24,-12, 14;
/M: SY='K';  M= -2, -1,-25, -3,  7,-25,-16,  8,-21, 15,-18, -6,  2,-13, 12,  8, -5, -9,-19,-23, -8,  9;
/M: SY='V';  M=  0,-19,-16,-20,-12, -7,-25,-19, 11,-15, 10,  6,-20,-22, -9,-14, -9,  0, 17,-26, -9,-11;
/M: SY='E';  M= -7, -1,-26,  3, 22,-23,-10,-10,-22,  6,-15,-12, -4, -9,  4, -1, -2, -4,-17,-26,-16, 13;
/M: SY='A';  M= 22, -1,-15, -6,  2,-21,  0,-13,-18, -7,-18,-15,  1,-10, -4,-13, 15,  5,-10,-28,-20, -1;
/M: SY='E';  M= -5, 11,-26, 17, 25,-28,-16, -5,-24,  6,-15,-14,  0, -8,  9, -2, -3, -9,-21,-28,-16, 17;
/M: SY='L';  M= -7,-17,-22,-18, -7, -5,-25, -2,  3,-15, 18,  7,-15,-21, -9,-12,-16, -7, -1,-23, -2, -9;
/I:         E1=0; IE=-105; DE=-105;
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_03 which contains 571'609 sequence entries.


Total number of hits 37 in 12 different sequences
Number of true positive hits 37 in 12 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Prokaryotes (Bacteria)
Maximum number of repetitions [info] 4
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] REPEAT
Feature description [info] C
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
12 sequences

ARP4_STRPY  (P13050), M12_STRPY   (P19401), M21_STRPY   (P50468), 
M22_STRPY   (P50469), M24_STRPY   (P12379), M49_STRP9   (P16947), 
M5_STRP5(P02977), M6A_STRP6   (Q5X9Q9), M6B_STRPY   (P08089), 
MX_STRP9(P16946), PAM_STRPY   (P49054), SPH_STRP1   (P50470)
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PDB
[Detailed view]
2 PDB

2KK9; 8SKV