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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU01373


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU01373
General rule information [?]

Accession PRU01373
Dates 23-JUN-2023 (Created)
23-JUN-2023 (Last updated, Version 2)
Data class Domain;
Predictors PROSITE; PS52029; LD_TPASE
Name L,D-transpeptidase (L,D-TPase) catalytic domain
Function Members of the L,D-transpeptidase family can also display L,D- carboxypeptidase and L,D-endopeptidase activities.
Scope(s) Bacteria
Example(s) C0SP99;

Propagated annotation [?]

Comments [?]

PATHWAYCell wall biogenesis; peptidoglycan biosynthesis.

Keywords [?]

Cell shape
Cell wall biogenesis/degradation
Peptidoglycan synthesis

Gene Ontology [?]

GO:0071555; Biological process:cell wall organization
GO:0008360; Biological process:regulation of cell shape

Features [?]

From: PS52029
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="L,D-TPase catalytic #"
ACT_SITE 83 83 /note="Proton donor/acceptor" H 1
ACT_SITE 99 99 /note="Nucleophile" C 1

Additional information [?]

Size range 108-181 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]