ProRule PRU01377
General rule information
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| Accession | PRU01377 |
| Dates | 28-JUL-2023 (Created)
-- (Last updated, Version 1) |
| Data class | Domain; |
| Predictors |
PROSITE; PS52033; CYSTATIN_LXN |
Name | Latexin (LXN)-type cystatin domain |
| Function | The LXN-type cystatin domains are packed against each other through the helices and linked by a connecting segment encompassing a third alpha- helix. The two domains are arranged so that there is a cleft in this part of the structure that can accommodate a peptide chain. |
| Scope(s) |
Eukaryota Euteleostomi |
| Example(s) | Q64361 (LXN_RAT); |
Propagated annotation
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Comments
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| SIMILARITY | Belongs to the protease inhibitor I47 (latexin) family. |
Keywords
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Gene Ontology
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| GO:0008191; Molecular function:metalloendopeptidase inhibitor activity |
Features
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| From: PS52033 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="Cystatin LXN-type #" | |||||||||
Additional information
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| Size range | 97-116 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 2 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [5] All [ 5 ]
- Retrieve set of proteins with 3D structure for this domain