We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
ProRule PRU01395
View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU01395
General rule information
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| Accession | PRU01395 |
| Dates | 13-SEP-2024 (Created)
13-SEP-2024 (Last updated, Version 2) |
| Data class | Domain; |
| Predictors |
PROSITE; PS52050; WYL |
Name | WYL domain |
| Function | The WYL (named for three conserved amino acids found in a subset of domains of this superfamily) domain is a nucleotide-sensing module that controls the activity of TFs involved in the regulation of DNA damage response and phage defense mechanisms in bacteria. |
| Scope(s) |
Bacteria |
| Example(s) | O34920; |
Propagated annotation
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Features
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| From: PS52050 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="WYL #" | |||||||||
Additional information
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| Size range | 74-81 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Bacteria [14] All [ 14 ]
- Retrieve set of proteins with 3D structure for this domain