ProRule PRU10004
General rule information
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| Accession | PRU10004 |
| Dates | 16-OCT-2006 (Created)
14-MAY-2022 (Last updated, Version 6) |
| Data class | Domain; |
| Predictors |
PROSITE; PS00068; MDH |
Name | Malate dehydrogenase active site |
| Function | Undefined |
| Scope(s) |
Eukaryota Bacteria |
| Example(s) | Q5U907 (MDH_ACTSZ); |
Propagated annotation
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Identifier, protein and gene names
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| Protein name | + AltName: Full=Malate dehydrogenase; EC=1.1.1.37; |
Comments
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| CATALYTIC ACTIVITY | Reaction=(S)-malate + NAD(+) = H(+) + NADH + oxaloacetate; Xref=Rhea:RHEA:21432, ChEBI:CHEBI:15378, ChEBI:CHEBI:15589, ChEBI:CHEBI:16452, ChEBI:CHEBI:57540, ChEBI:CHEBI:57945; EC=1.1.1.37; |
Features
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| From: PS00068 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| ACT_SITE | 5 | 5 | /note="Proton relay" | |||||||||
| BINDING | 6 | 6 | /ligand="substrate" | |||||||||
Additional information
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| Size range | unlimited amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Bacteria [300] Eukaryota [66] All [ 366 ]
- Retrieve set of proteins with 3D structure for this domain