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annotation rule: PRU10004

General rule information [?]

Accession PRU10004
Dates 16-OCT-2006 (Created)
27-OCT-2018 (Last updated, Version 4)
Data class Domain
Predictors PROSITE; PS00068; MDH
Name Malate dehydrogenase active site
Function Undefined.

Propagated annotation [?]


Description [?]

+ AltName: Full=Malate dehydrogenase; EC=1.1.1.37;

Comments [?]

Catalytic activity Reaction=(S)-malate + NAD(+) = H(+) + NADH + oxaloacetate; Xref=Rhea:RHEA:21432, ChEBI:CHEBI:15378, ChEBI:CHEBI:15589, ChEBI:CHEBI:16452, ChEBI:CHEBI:57540, ChEBI:CHEBI:57945; EC=1.1.1.37;.

Features [?]

From: PS00068
Key     From     To       Description   Tag   Condition   FTGroup
ACT_SITE     5     5       Proton relay        
BINDING     6     6       Substrate        

Additional information [?]

Size range unlimited amino acids
Related rules None
Repeats 1
Topology Undefined
Example Q5U907 (MDH_ACTSZ)
Scope
Eukaryota
Bacteria

Copyright

PROSITE is copyright. It is produced by the SIB Swiss Institute Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified. Usage by and for commercial entities requires a license agreement. For information about the licensing scheme send an email to license@isb-sib.ch or see: prosite_license.html.



UniProtKB rule member sequences [?]