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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU10014


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU10014
General rule information [?]

Accession PRU10014
Dates 16-OCT-2006 (Created)
03-SEP-2024 (Last updated, Version 10)
Data class Domain;
Predictors PROSITE; PS00368; RIBORED_SMALL
Name Ribonucleotide reductase small subunit
Function Undefined
Scope(s) Eukaryota
Bacteria
Viruses
Example(s) P26713;

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name + AltName: Full=Ribonucleoside-diphosphate reductase;
                 EC=1.17.4.1;

Comments [?]

CATALYTIC ACTIVITY Reaction=a 2'-deoxyribonucleoside 5'-diphosphate + [thioredoxin]- disulfide + H2O = a ribonucleoside 5'-diphosphate + [thioredoxin]- dithiol; Xref=Rhea:RHEA:23252, Rhea:RHEA-COMP:10698, Rhea:RHEA- COMP:10700, ChEBI:CHEBI:15377, ChEBI:CHEBI:29950, ChEBI:CHEBI:50058, ChEBI:CHEBI:57930, ChEBI:CHEBI:73316; EC=1.17.4.1;

Features [?]

From: PS00368
Key From To Description Tag Condition FTGroup
BINDING 2 2 /ligand="Fe cation"
/ligand_id="ChEBI:CHEBI:24875"
/ligand_label="1"
BINDING 4 4 /ligand="Fe cation"
/ligand_id="ChEBI:CHEBI:24875"
/ligand_label="1"
ACT_SITE 7 7

Additional information [?]

Size range unlimited amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]