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annotation rule: PRU10130

General rule information [?]

Accession PRU10130
Dates 16-OCT-2006 (Created)
22-NOV-2019 (Last updated, Version 7)
Data class Domain
Predictors PROSITE; PS00176; TOPOISOMERASE_I_EUK
Name Eukaryotic DNA topoisomerase I active site
Function Undefined.

Propagated annotation [?]


Description [?]

+ AltName: Full=DNA topoisomerase; EC 5.6.2.1;

Comments [?]

Catalytic activity Reaction=ATP-independent breakage of single-stranded DNA, followed by passage and rejoining.; EC=5.6.2.1;

Features [?]

From: PS00176
Key     From     To       Description   Tag   Condition   FTGroup
ACT_SITE     6     6       O-(3'-phospho-DNA)-tyrosine intermediate        

Additional information [?]

Size range unlimited amino acids
Related rules None
Repeats 1
Topology Undefined
Example Q76ZS7 (TOP1_VACCA)
Scope
Eukaryota
Viruses

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.



UniProtKB rule member sequences [?]