PRU10130
General rule information
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| Accession | PRU10130 |
| Dates | 16-OCT-2006 (Created) 22-NOV-2019 (Last updated, Version 7) |
| Data class | Domain |
| Predictors | PROSITE; PS00176; TOPOISOMERASE_I_EUK |
| Name | Eukaryotic DNA topoisomerase I active site |
| Function | Undefined. |
Propagated annotation
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Description
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| + AltName: Full=DNA topoisomerase; EC 5.6.2.1; |
Comments
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| Catalytic activity | Reaction=ATP-independent breakage of single-stranded DNA, followed by passage and rejoining.; EC=5.6.2.1; |
Features
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| From: PS00176 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| ACT_SITE | 6 | 6 | O-(3'-phospho-DNA)-tyrosine intermediate | |||||||||
Additional information
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| Size range | unlimited amino acids |
| Related rules | None |
| Repeats | 1 |
| Topology | Undefined |
| Example | Q76ZS7 (TOP1_VACCA) |
| Scope | Eukaryota
Viruses |
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UniProtKB rule member sequences
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UniProtKB/Swiss-Prot sets
Eukaryota [21] Viruses [7] All [ 28 ]
- Retrieve set of proteins with 3D structure for this domain