ProRule PRU10131

General rule information [?]

Accession PRU10131
Dates 16-OCT-2006 (Created)
28-SEP-2023 (Last updated, Version 8)
Data class Domain;
Predictors PROSITE; PS00396; TOPO_IA_1
Name Topoisomerase (Topo) IA-type active site
Function Undefined
Scope(s) Eukaryota
Example(s) Q9KA23 (TOP1_HALH5);

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name + AltName: Full=DNA topoisomerase;

Comments [?]

CATALYTIC ACTIVITY Reaction=ATP-independent breakage of single-stranded DNA, followed by passage and rejoining.; EC=;

Features [?]

From: PS00396
Key From To Description Tag Condition FTGroup
ACT_SITE 7 7 /note="O-(5'-phospho-DNA)-tyrosine intermediate"

Additional information [?]

Size range unlimited amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined


PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

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UniProtKB rule member sequences [?]