ProRule PRU10131
General rule information
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| PURL | https://purl.expasy.org/prosite/rule/PRU10131 |
| Accession | PRU10131 |
| Dates | 16-OCT-2006 (Created)
28-SEP-2023 (Last updated, Version 8) |
| Data class | Domain; |
| Predictors |
PROSITE; PS00396; TOPO_IA_1 |
Name | Topoisomerase (Topo) IA-type active site |
| Function | Undefined |
| Scope(s) |
Eukaryota Bacteria Archaea Viruses |
| Example(s) | Q9KA23 (TOP1_HALH5); |
Propagated annotation
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Identifier, protein and gene names
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| Protein name | + AltName: Full=DNA topoisomerase; EC=5.6.2.1; |
Comments
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| CATALYTIC ACTIVITY | Reaction=ATP-independent breakage of single-stranded DNA, followed by passage and rejoining.; EC=5.6.2.1; |
Features
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| From: PS00396 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| ACT_SITE | 7 | 7 | /note="O-(5'-phospho-DNA)-tyrosine intermediate" | |||||||||
Additional information
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| Size range | unlimited amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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