ProRule PRU10131
General rule information
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Accession | PRU10131 |
Dates | 16-OCT-2006 (Created)
28-SEP-2023 (Last updated, Version 8) |
Data class | Domain; |
Predictors |
PROSITE; PS00396; TOPO_IA_1 |
Name | Topoisomerase (Topo) IA-type active site |
Function | Undefined |
Scope(s) |
Eukaryota Bacteria Archaea Viruses |
Example(s) | Q9KA23 (TOP1_HALH5); |
Propagated annotation
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Identifier, protein and gene names
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Protein name | + AltName: Full=DNA topoisomerase; EC=5.6.2.1; |
Comments
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CATALYTIC ACTIVITY | Reaction=ATP-independent breakage of single-stranded DNA, followed by passage and rejoining.; EC=5.6.2.1; |
Features
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From: PS00396 | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
ACT_SITE | 7 | 7 | /note="O-(5'-phospho-DNA)-tyrosine intermediate" |
Additional information
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Size range | unlimited amino acids |
Related rules |
None |
Fusion | None |
Repeats | 1 |
Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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