ProRule PRU10138

General rule information [?]

Accession PRU10138
Dates 21-AUG-2009 (Created)
22-NOV-2019 (Last updated, Version 3)
Data class Domain;
Predictors PROSITE; PS00014; ER_TARGET
Name Endoplasmic reticulum targeting sequence
Function Proteins that permanently reside in the lumen of the endoplasmic reticulum (ER) seem to be distinguished from newly synthesized secretory proteins by the presence of the C-terminal sequence Lys-Asp-Glu-Leu (KDEL).
Scope(s) Eukaryota
Example(s) Q9Y2B0 (CNPY2_HUMAN);

Propagated annotation [?]

Comments [?]

SUBCELLULAR LOCATIONEndoplasmic reticulum.

Keywords [?]

Gene Ontology [?]

GO:0005783; Cellular component:endoplasmic reticulum

Features [?]

From: PS00014
Key From To Description Tag Condition FTGroup
MOTIF from to /note="Prevents secretion from ER"

Additional information [?]

Size range 4 amino acids
Related rules None
Fusion None
Repeats 1
Topology Not cytoplasmic


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UniProtKB rule member sequences [?]