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ProRule PRU10145


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PURL: https://purl.expasy.org/prosite/rule/PRU10145
General rule information [?]

Accession PRU10145
Dates 09-FEB-2024 (Created)
20-MAR-2025 (Last updated, Version 5)
Data class Domain;
Predictors PROSITE; PS01030; RNA_POL_M_15KD
Name RNA polymerases M / 15 Kd subunits
Function These proteins contain a probable zinc finger in their N-terminal region.
Scope(s) Eukaryota
Archaea
Example(s) Q07271 (TFS_SULAC);

Propagated annotation [?]

Comments [?]

SIMILARITYBelongs to the archaeal RpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.

Keywords [?]

Metal-binding
Zinc
end case
Transcription
DNA-directed RNA polymerase
case <OC:Eukaryota>
Nucleus
end case

Gene Ontology [?]

GO:0003899; Molecular function:DNA-directed RNA polymerase activity
GO:0003676; Molecular function:nucleic acid binding
case <FTGroup:1>
GO:0008270; Molecular function:zinc ion binding

Features [?]

From: PS01030
Key From To Description Tag Condition FTGroup
BINDING 2 2 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 C 1
BINDING 5 5 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 C 1
BINDING 10 10 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 C 1
BINDING 11 11 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 C 1

Additional information [?]

Size range 20-27 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

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UniProtKB rule member sequences [?]