ProRule PRU00957

Accession	PRU00957
Dates	14-DEC-2011 (Created) 13-OCT-2023 (Last updated, Version 12)
Data class	Domain;
Predictors	PROSITE; PS51625; SAM_MT_TRMB
Name	tRNA (guanine-N(7)-)-methyltransferase
Function	tRNA (guanine-N(7)-)-methyltransferase (EC 2.1.1.33) is an enzyme that transfers a methyl group from S-adenosyl-L-methionine (SAM) to tRNA to form tRNA containing N(7)-methylguanine and S-adenosyl-L-homocysteine.
Scope(s)	Bacteria Eukaryota
Example(s)	Q6NU94 (TRMB_XENLA);

From: PS51625
Key	From	To	Description	Tag	Condition	FTGroup
case <OC:Eukaryota> and <Feature:PS51625:74-75=E-[IL]>
BINDING	74	75	/ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789"
end case
case <OC:Eukaryota> and <Feature:PS51625:101-102=N-[AST]>
BINDING	101	102	/ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789"
end case
case <OC:Eukaryota> and <Feature:PS51625:197=T>
BINDING	197	199	/ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789"
end case
case <OC:Bacteria> and <Feature:PS51625:197-200=T-[AEKNRSY]-[FY]-E>
BINDING	197	200	/ligand="substrate"
end case
ACT_SITE	124	124			D
case <OC:Bacteria>
BINDING	49	49	/ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789"		[DE]
end case
case <OC:Eukaryota>
BINDING	51	51	/ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789"		G
end case
case <OC:Bacteria>
BINDING	74	74	/ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789"		[DE]
BINDING	101	101	/ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789"		[DEN]
end case
case <OC:Eukaryota>
BINDING	121	121	/ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789"		[CL]
end case
case <OC:Bacteria>
BINDING	124	124	/ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789"		D
BINDING	128	128	/ligand="substrate"		K
BINDING	160	160	/ligand="substrate"		D
end case