ProRule PRU01051

Accession	PRU01051
Dates	20-MAY-2020 (Created) -- (Last updated, Version 1)
Data class	Domain;
Predictors	PROSITE; PS51714; G_BMS1
Name	Bms1-type guanine nucleotide-binding (G) domain
Function	Bms1p and Tsr1p represent a new family of factors required for ribosome biogenesis. They are each independently required for 40S ribosomal subunit biogenesis. Bms1p, a protein required for pre-rRNA processing, contains an evolutionarily conserved G domain with five conserved polypeptide loops designated G1 through G5, which form contact sites with the guanine nucleotide or coordinate the Mg(2+) ion. Tsr1p lacks a P-loop and is not predicted to bind GTP.
Scope(s)	Eukaryota
Example(s)	Q07381 (TSR1_YEAST);

From: PS51714
Key	From	To	Description	Tag	Condition	FTGroup
DOMAIN	from	to	/note="Bms1-type G #"
REGION	10	17	/note="G1 #"		G-x(4)-G-K-[ST]	1
REGION	42	46	/note="G2 #"		x(2)-T-x(2)	1
REGION	57	60	/note="G3 #"		E-x(3)	1
REGION	110	113	/note="G4 #"		T-H-x-D	1
REGION	144	146	/note="G5 #"			1