Home ScanProsite ProRule Documents Downloads Links Funding
PROSITE documentation PDOC00313

Ribosomal protein S15 signature

Description:

Ribosomal protein S15 is one of the proteins from the small ribosomal subunit. In Escherichia coli, this protein binds to 16S ribosomal RNA and functions at early steps in ribosome assembly. It belongs to a family of ribosomal proteins which, on the basis of sequence similarities [1,2], groups:

  • Eubacterial S15.
  • Archaebacterial Halobacterium marismortui HmaS15 (HS11).
  • Plant chloroplast S15.
  • Yeast mitochondrial S28.
  • Mammalian S13.
  • Brugia pahangi and Wuchereria bancrofti S13 (S15).
  • Yeast S13 (YS15).

S15 is a protein of 80 to 250 amino-acid residues. As a signature pattern, we selected a conserved region located in the C-terminal part of these proteins.

Expert(s) to contact by email:

Ellis S.R.

Last update:

December 2004 / Pattern and text revised.

Technical section:

PROSITE method (with tools and information) covered by this documentation:

RIBOSOMAL_S15, PS00362; Ribosomal protein S15 signature  (PATTERN)
Consensus pattern: [LIVM]-x(2)-H-[LIVMFY]-x(3)-{S}-x-D-x(2)-[STAGN]-x(3)-[LF]-x(2)-{A}-x(6)-[LIVM]-x(2)-[FY]
Sequences known to belong to this class detected by the pattern: ALL
Other sequence(s) detected in Swiss-Prot: 2.
• Retrieve an alignment of Swiss-Prot true positive hits:
  Clustal format, color, condensed view  / Clustal format, color  / Clustal format, plain text  / Fasta format
• Retrieve the sequence logo from the alignment
• Taxonomic tree view of all Swiss-Prot/TrEMBL entries matching PS00362
• Retrieve a list of all Swiss-Prot/TrEMBL entries matching PS00362
• Scan Swiss-Prot/TrEMBL entries against PS00362
• view ligand binding statistics
Matching PDB structures: 1A32 1AB3 1DK1 1EG0 ... [ALL]

References:

1 AuthorsDang H., Ellis S.R.
TitleStructural and functional analyses of a yeast mitochondrial ribosomal protein homologous to ribosomal protein S15 of Escherichia coli.
SourceNucleic Acids Res. 18:6895-6901(1990).
PubMed ID2263452
2 AuthorsOtaka E., Hashimoto T., Mizuta K.
SourceProtein Seq. Data Anal. 5:285-300(1993).

Copyright:

PROSITE is copyright. It is produced by the Swiss Institute of Bioinformatics (SIB). There are no restrictions on its use by non-profit institutions as long as its content is in no way modified. Usage by and for commercial entities requires a license agreement. For information about the licensing scheme send an email to license@isb-sib.ch or see: http://www.expasy.org/prosite/prosite_license.htm.

Miscellaneous:

View entry in original PROSITE document format
View entry in raw text format (no links)