PROSITE documentation PDOC00590

Ribosomal protein S17e signature

Description:

A number of eukaryotic and archaebacterial ribosomal proteins can be grouped on the basis of sequence similarities. One of these families consists of:

  • Vertebrates S17 [1].
  • Drosophila S17 [2].
  • Neurospora crassa S17 (crp-3).
  • Yeast S17a (RP51A) and S17b (RP51B) [3].
  • Archaebacterial S17e.

These proteins have from 63 (in archebacteria) to 130 to 146 amino acids and are highly conserved. As a signature, we selected a region in the central part of these proteins.

Last update:

April 2006 / Pattern revised.

Technical section:

PROSITE method (with tools and information) covered by this documentation:

RIBOSOMAL_S17E, PS00712Ribosomal protein S17e signature  (PATTERN)
Consensus pattern: [IVDYPKS]-x-[ST]-K-x-[LIVMTF]-[RIKM]-N-x-[IV]-[SA]-G-[FY]-x-[TV]-[HKRA]
Sequences known to belong to this class detected by the pattern: ALL
Other sequence(s) detected in Swiss-Prot: NONE
• Retrieve an alignment of Swiss-Prot true positive hits:
  Clustal format, color, condensed view  / Clustal format, color  / Clustal format, plain text  / Fasta format
Retrieve the sequence logo from the alignment
Taxonomic tree view of all Swiss-Prot/TrEMBL entries matching PS00712
Retrieve a list of all Swiss-Prot/TrEMBL entries matching PS00712
Scan Swiss-Prot/TrEMBL entries against PS00712
view ligand binding statistics
Matching PDB structures: 1RQ6 3IZB 3O2Z 3O30 [ALL]

References:

1 AuthorsChen I.-T., Roufa D.J.
TitleThe transcriptionally active human ribosomal protein S17 gene.
SourceGene 70:107-116(1988).
PubMed ID3240863
2 AuthorsMaki C., Rhoads D.D., Stewart M.J., Van Slyke B., Roufa D.J.
TitleThe Drosophila melanogaster RPS17 gene encoding ribosomal protein S17.
SourceGene 79:289-298(1989).
PubMed ID2507396
3 AuthorsAbovich N., Rosbash M.
TitleTwo genes for ribosomal protein 51 of Saccharomyces cerevisiae complement and contribute to the ribosomes.
SourceMol. Cell. Biol. 4:1871-1879(1984).
PubMed ID6092944

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