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PROSITE documentation PDOC00898

Ribosomal protein S27e signature

Description:

A number of eukaryotic and archaebacterial ribosomal proteins can be grouped on the basis of sequence similarities. One of these families consists of [1]:

  • Mammalian S27 (human S27 was originally known as metallopan-stimulin 1).
  • Chlamydomonas reinhardtii S27.
  • Entamoeba histolytica S27.
  • Yeast S27.
  • Archaebacterial S27e.

These proteins have from 57 to 99 amino acids. They contain, in their central section, a putative zinc-finger region of the type C-x(2)-C-x(14)-C-x(2)-C. We have selected that region as a signature pattern.

Last update:

December 2004 / Pattern and text revised.

Technical section:

PROSITE method (with tools and information) covered by this documentation:

RIBOSOMAL_S27E, PS01168; Ribosomal protein S27e signature  (PATTERN)
Consensus pattern: [QKRTE]-C-x(2)-C-x(6)-F-[GSDA]-x-[PSA]-x(5)-C-x(2)-C-[GSAQ]-x(2)-[LIV]-x(2)-[PS]-x-G
The 4 C's may be zinc ligands
Sequences known to belong to this class detected by the pattern: ALL
Other sequence(s) detected in Swiss-Prot: NONE
• Retrieve an alignment of Swiss-Prot true positive hits:
  Clustal format, color, condensed view  / Clustal format, color  / Clustal format, plain text  / Fasta format
• Retrieve the sequence logo from the alignment
• Taxonomic tree view of all Swiss-Prot/TrEMBL entries matching PS01168
• Retrieve a list of all Swiss-Prot/TrEMBL entries matching PS01168
• Scan Swiss-Prot/TrEMBL entries against PS01168
• view ligand binding statistics
Matching PDB structures: 1QXF 3IZB [ALL]

Reference:

1 AuthorsChan Y.-L., Suzuki K., Olvera J., Wool I.G.
TitleZinc finger-like motifs in rat ribosomal proteins S27 and S29.
SourceNucleic Acids Res. 21:649-655(1993).
PubMed ID8441676

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