Entry: PS00019

General information about the entry
Entry name ACTININ_1
Accession number PS00019
Entry type PATTERN
Date APR-1990 (CREATED); APR-2006 (DATA UPDATE); MAR-2013 (INFO UPDATE).
PROSITE Documentation PDOC00019
Name and characterization of the entry
DescriptionActinin-type actin-binding domain signature 1.
Pattern [EQ]-{LNYH}-x-[ATV]-[FY]-{LDAM}-{T}-W-{PG}-N.
Numerical results
  • UniProtKB/Swiss-Prot release number: 2013_05, total number of sequence entries in that release: 540052.
  • Total number of hits in UniProtKB/Swiss-Prot: 112 hits in 99 different sequences
  • Number of hits on proteins that are known to belong to the set under consideration: 93 hits in 80 different sequences
  • Number of hits on proteins that could potentially belong to the set under consideration: 0 hits in 0 different sequences
  • Number of false hits (on unrelated proteins): 19 hits in 19 different sequences
  • Number of known missed hits: 5
  • Number of partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences: 2
  • Precision (true hits / (true hits + false positives)): 83.04 %
  • Recall (true hits / (true hits + false negatives)): 94.90 %
Comments
  • Taxonomic range: Eukaryotes
  • Maximum known number of repetitions of the pattern in a single protein: 2
  • VERSION: 2
Cross-references
UniProtKB/Swiss-Prot True positive hits:
ACTN1_BOVIN (Q3B7N2), ACTN1_CHICK (P05094), ACTN1_HUMAN (P12814), 
ACTN1_MACFA (Q2PFV7), ACTN1_MOUSE (Q7TPR4), ACTN1_RAT   (Q9Z1P2), 
ACTN2_BOVIN (Q3ZC55), ACTN2_CHICK (P20111), ACTN2_HUMAN (P35609), 
ACTN2_MOUSE (Q9JI91), ACTN3_BOVIN (Q0III9), ACTN3_HUMAN (Q08043), 
ACTN3_MOUSE (O88990), ACTN4_BOVIN (A5D7D1), ACTN4_CHICK (Q90734), 
ACTN4_HUMAN (O43707), ACTN4_MOUSE (P57780), ACTN4_PONAB (Q5RCS6), 
ACTN4_RAT   (Q9QXQ0), ACTNA_DICDI (P05095), ACTNB_DICDI (O76329), 
ACTN_ANOGA  (Q7PKQ5), ACTN_DROME  (P18091), ANC1_CAEEL  (Q9N4M4), 
CLMN_HUMAN  (Q96JQ2), CLMN_MOUSE  (Q8C5W0), CTXA_DICDI  (Q54HG2), 
CTXA_POLPA  (Q9Y0T4), CTXB_DICDI  (Q550R2), DMDA_DROME  (Q9VDW6), 
DMD_CAEEL   (Q9TW65), DMD_CANFA   (O97592), DMD_CHICK   (P11533), 
DMD_HUMAN   (P11532), DMD_MOUSE   (P11531), DMD_PIG     (Q5GN48), 
DYST_HUMAN  (Q03001), DYST_MOUSE  (Q91ZU6), FIMB_DICDI  (P54680), 
FIMB_SCHPO  (O59945), FIMB_YEAST  (P32599), FLNA_DROME  (Q9VEN1), 
FLNA_HUMAN  (P21333), FLNA_MOUSE  (Q8BTM8), FLNB_HUMAN  (O75369), 
FLNB_MOUSE  (Q80X90), FLNC_HUMAN  (Q14315), FLNC_MOUSE  (Q8VHX6), 
GELA_DICDI  (P13466), MACF1_HUMAN (Q9UPN3), MACF1_MOUSE (Q9QXZ0), 
MACF1_RAT   (D3ZHV2), PLEC_HUMAN  (Q15149), PLEC_MOUSE  (Q9QXS1), 
PLSI_BOVIN  (A6H742), PLSI_CHICK  (P19179), PLSI_HUMAN  (Q14651), 
PLSI_MOUSE  (Q3V0K9), PLSL_DANRE  (Q6P698), PLSL_HUMAN  (P13796), 
PLSL_MOUSE  (Q61233), PLST_BOVIN  (A7E3Q8), PLST_CRIGR  (O88818), 
PLST_HUMAN  (P13797), PLST_MOUSE  (Q99K51), PLST_RAT    (Q63598), 
SPTB1_HUMAN (P11277), SPTB1_MOUSE (P15508), SPTB2_HUMAN (Q01082), 
SPTB2_MOUSE (Q62261), SPTCB_DROME (Q00963), SPTN2_HUMAN (O15020), 
SPTN2_RAT   (Q9QWN8), SPTN4_HUMAN (Q9H254), SPTN5_HUMAN (Q9NRC6), 
SYNE1_HUMAN (Q8NF91), SYNE1_MOUSE (Q6ZWR6), SYNE2_HUMAN (Q8WXH0), 
SYNE2_MOUSE (Q6ZWQ0), UTRO_HUMAN  (P46939)
False negative hits (sequences which belong to the set under consideration, but which have not been picked up by the pattern or profile):
AIN1_SCHPO  (O13728), FIMB1_ARATH (Q7G188), FIMB2_ARATH (Q9FKI0), 
FIMB3_ARATH (Q9FJ70), PLEC_RAT    (P30427)
`Potential' hits (partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences):
DMD_RAT     (P11530), PLEC_CRIGR  (Q9JI55)
False positive hits (sequences which do not belong to the set under consideration):
CARDB_CYNCA (Q9XFX4), CATA_MICLU  (P29422), CELA1_HUMAN (Q9UNI1), 
CRF2_ASPFU  (Q4WI46), CSLG1_ARATH (Q570S7), CSLG2_ARATH (Q8VYR4), 
CSLG3_ARATH (Q0WVN5), CYPR1_CYNCA (P40782), INT1_HUMAN  (Q8N201), 
INT1_MOUSE  (Q6P4S8), MTMR7_MOUSE (Q9Z2C9), OPSB_ASPOR  (Q8NKB6), 
RDRP_OCSVU  (Q83927), RNA14_SCHPO (O14233), SEPF_CLOD6  (Q182V6), 
STAB2_MOUSE (Q8R4U0), UL07_VZVD   (P09301), YE9G_SCHPO  (O13776), 
ZDHC7_DICDI (Q552M6)
Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:

[Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format]

Retrieve the sequence logo from the alignment

PDB
[Detailed view]
1AOA; 1DXX; 1MB8; 1QAG; 1RT8; 1SH5; 1SH6; 1SJJ; 1TJT; 1WKU; 2EYI; 2EYN; 2R0O; 2WA5; 2WA6; 2WA7; 2WFN; 3F7P; 3FER; 3HOC; 3HOP; 3HOR; 3LUE; 4B7L;

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