Entry: PS00066

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General information about the entry

Entry name [info] HMG_COA_REDUCTASE_1
Accession [info] PS00066
Entry type [info] PATTERN
Date [info] APR-1990 (CREATED); APR-2006 (DATA UPDATE); JUL-2014 (INFO UPDATE).
PROSITE Doc. [info] PDOC00064

Name and characterization of the entry

Description [info] Hydroxymethylglutaryl-coenzyme A reductases signature 1.
Pattern [info]
[RKH]-x-{Y}-{I}-x-{I}-{L}-D-x-M-G-x-N-x-[LIVMA].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2014_09 which contains 546'439 sequence entries.


Total number of hits 62 in 62 different sequences
Number of true positive hits 53 in 53 different sequences
Number of 'unknown' hits
Number of false positive hits 9 in 9 different sequences
Number of false negative sequences 2
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 85.48 %
Recall (true positives / (true positives + false negatives)) 96.36 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
53 sequences

HMDH1_ARATH (P14891), HMDH1_DICDI (P34135), HMDH1_GOSHI (O64966), 
HMDH1_HEVBR (P29057), HMDH1_ORYSI (A2X8W3), HMDH1_ORYSJ (Q0DY59), 
HMDH1_YEAST (P12683), HMDH2_ARATH (P43256), HMDH2_CAPAN (Q9XEL8), 
HMDH2_DICDI (P34136), HMDH2_GOSHI (O64967), HMDH2_SOLLC (P48022), 
HMDH2_SOLTU (Q41437), HMDH2_YEAST (P12684), HMDH3_HEVBR (Q00583), 
HMDH3_ORYSJ (Q9XHL5), HMDH3_SOLTU (Q41438), HMDH_AERPE  (Q9YAS4), 
HMDH_AGRIP  (O76819), HMDH_ARCFU  (O28538), HMDH_ASPTE  (Q9Y7D2), 
HMDH_ASPTN  (Q0C8L9), HMDH_BLAGE  (P54960), HMDH_BOVIN  (A7Z064), 
HMDH_CAMAC  (P48021), HMDH_CATRO  (Q03163), HMDH_CRIGR  (P00347), 
HMDH_CYBJA  (O74164), HMDH_DROME  (P14773), HMDH_GIBF5  (S0DQM8), 
HMDH_GIBFU  (P0CT44), HMDH_HALS3  (B0R6J9), HMDH_HALVD  (Q59468), 
HMDH_HUMAN  (P04035), HMDH_MAIZE  (O24594), HMDH_MESAU  (P09610), 
HMDH_METJA  (Q58116), HMDH_METTH  (O26662), HMDH_MOUSE  (Q01237), 
HMDH_NICSY  (Q01559), HMDH_PHYB8  (Q12649), HMDH_PIG    (Q1W675), 
HMDH_PONAB  (Q5R6N3), HMDH_PYRAB  (Q9V1R3), HMDH_PYRHO  (O59469), 
HMDH_RABIT  (Q29512), HMDH_RAT    (P51639), HMDH_SCHMA  (P16237), 
HMDH_SCHPO  (Q10283), HMDH_STRPU  (P16393), HMDH_SULSO  (O08424), 
HMDH_XENLA  (P20715), MVAA_PSEMV  (P13702)
» More

UniProtKB/Swiss-Prot
False negative sequences
2 sequences

HMDH1_SOLTU (P48020), HMDH_BORBU  (O51628)

		
UniProtKB/Swiss-Prot
'Partial' sequences
1 sequence

HMDH2_HEVBR (P29058)

		
UniProtKB/Swiss-Prot
False positive sequences
9 sequences

BP27_BPT4   (P17172), GLT2_CROSA  (Q6X1C0), LIPR3_HUMAN (Q17RR3), 
MSP_TRELE   (Q8RMC0), RH48_ARATH  (Q9C8S9), RN5A_MOUSE  (Q05921), 
SYP_STRA1   (Q3JZ37), SYP_STRA3   (Q8E362), SYP_STRA5   (Q8DXD8)
» More

PDB
[Detailed view]
33 PDB

1DQ8; 1DQ9; 1DQA; 1HW8; 1HW9; 1HWI; 1HWJ; 1HWK; 1HWL; 1QAX; 1QAY; 1R31; 1R7I; 1T02; 2Q1L; 2Q6B; 2Q6C; 2R4F; 3BGL; 3CCT; 3CCW; 3CCZ; 3CD0; 3CD5; 3CD7; 3CDA; 3CDB; 4I4B; 4I56; 4I64; 4I6A; 4I6W; 4I6Y
» More

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