Entry: PS00066

General information about the entry

Entry name [info] HMG_COA_REDUCTASE_1
Accession [info] PS00066
Entry type [info] PATTERN
Date [info] APR-1990 (CREATED); APR-2006 (DATA UPDATE); JUN-2015 (INFO UPDATE).
PROSITE Doc. [info] PDOC00064

Name and characterization of the entry

Description [info] Hydroxymethylglutaryl-coenzyme A reductases signature 1.
Pattern [info]
[RKH]-x-{Y}-{I}-x-{I}-{L}-D-x-M-G-x-N-x-[LIVMA].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2015_08 which contains 320'201 sequence entries.


Total number of hits 62 in 62 different sequences
Number of true positive hits 53 in 53 different sequences
Number of 'unknown' hits 0
Number of false positive hits 9 in 9 different sequences
Number of false negative sequences 2
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 85.48 %
Recall (true positives / (true positives + false negatives)) 96.36 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
53 sequences

HMDH1_ARATH (P14891), HMDH1_DICDI (P34135), HMDH1_GOSHI (O64966), 
HMDH1_HEVBR (P29057), HMDH1_ORYSI (A2X8W3), HMDH1_ORYSJ (Q0DY59), 
HMDH1_YEAST (P12683), HMDH2_ARATH (P43256), HMDH2_CAPAN (Q9XEL8), 
HMDH2_DICDI (P34136), HMDH2_GOSHI (O64967), HMDH2_SOLLC (P48022), 
HMDH2_SOLTU (Q41437), HMDH2_YEAST (P12684), HMDH3_HEVBR (Q00583), 
HMDH3_ORYSJ (Q9XHL5), HMDH3_SOLTU (Q41438), HMDH_AERPE  (Q9YAS4), 
HMDH_AGRIP  (O76819), HMDH_ARCFU  (O28538), HMDH_ASPTE  (Q9Y7D2), 
HMDH_ASPTN  (Q0C8L9), HMDH_BLAGE  (P54960), HMDH_BOVIN  (A7Z064), 
HMDH_CAMAC  (P48021), HMDH_CATRO  (Q03163), HMDH_CRIGR  (P00347), 
HMDH_CYBJA  (O74164), HMDH_DROME  (P14773), HMDH_GIBF5  (S0DQM8), 
HMDH_GIBFU  (P0CT44), HMDH_HALS3  (B0R6J9), HMDH_HALVD  (Q59468), 
HMDH_HUMAN  (P04035), HMDH_MAIZE  (O24594), HMDH_MESAU  (P09610), 
HMDH_METJA  (Q58116), HMDH_METTH  (O26662), HMDH_MOUSE  (Q01237), 
HMDH_NICSY  (Q01559), HMDH_PHYB8  (Q12649), HMDH_PIG    (Q1W675), 
HMDH_PONAB  (Q5R6N3), HMDH_PYRAB  (Q9V1R3), HMDH_PYRHO  (O59469), 
HMDH_RABIT  (Q29512), HMDH_RAT    (P51639), HMDH_SCHMA  (P16237), 
HMDH_SCHPO  (Q10283), HMDH_STRPU  (P16393), HMDH_SULSO  (O08424), 
HMDH_XENLA  (P20715), MVAA_PSEMV  (P13702)
» More

UniProtKB/Swiss-Prot
False negative sequences
2 sequences

HMDH1_SOLTU (P48020), HMDH_BORBU  (O51628)

		
UniProtKB/Swiss-Prot
'Partial' sequences
1 sequence

HMDH2_HEVBR (P29058)

		
UniProtKB/Swiss-Prot
False positive sequences
9 sequences

BP27_BPT4   (P17172), GLT2_CROSA  (Q6X1C0), LIPR3_HUMAN (Q17RR3), 
MSP_TRELE   (Q8RMC0), RH48_ARATH  (Q9C8S9), RN5A_MOUSE  (Q05921), 
SYP_STRA1   (Q3JZ37), SYP_STRA3   (Q8E362), SYP_STRA5   (Q8DXD8)
» More

PDB
[Detailed view]
33 PDB

1DQ8; 1DQ9; 1DQA; 1HW8; 1HW9; 1HWI; 1HWJ; 1HWK; 1HWL; 1QAX; 1QAY; 1R31; 1R7I; 1T02; 2Q1L; 2Q6B; 2Q6C; 2R4F; 3BGL; 3CCT; 3CCW; 3CCZ; 3CD0; 3CD5; 3CD7; 3CDA; 3CDB; 4I4B; 4I56; 4I64; 4I6A; 4I6W; 4I6Y
» More

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