Entry: PS00071

Forthcoming changes to the profile format
General information about the entry

Entry name [info] GAPDH
Accession [info] PS00071
Entry type [info] PATTERN
Date [info] APR-1990 (CREATED); DEC-2004 (DATA UPDATE); JUL-2014 (INFO UPDATE).
PROSITE Doc. [info] PDOC00069
Associated ProRule [info] PRU10009

Name and characterization of the entry

Description [info] Glyceraldehyde 3-phosphate dehydrogenase active site.
Pattern [info]
[ASV]-S-C-[NT]-T-{S}-x-[LIM].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2014_09 which contains 546'439 sequence entries.


Total number of hits 400 in 400 different sequences
Number of true positive hits 390 in 390 different sequences
Number of 'unknown' hits
Number of false positive hits 10 in 10 different sequences
Number of false negative sequences 25
Number of 'partial' sequences 8
Precision (true positives / (true positives + false positives)) 97.50 %
Recall (true positives / (true positives + false negatives)) 93.98 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] active_site at position 3
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
390 sequences

E4PD_CITK8  (A8APE1), E4PD_CROS8  (A7MJQ2), E4PD_ECO24  (A7ZR35), 
E4PD_ECO27  (B7UHW9), E4PD_ECO45  (B7MMA9), E4PD_ECO55  (B7LFI3), 
E4PD_ECO57  (P0A9B8), E4PD_ECO5E  (B5YQB9), E4PD_ECO7I  (B7NHY6), 
E4PD_ECO81  (B7MZM0), E4PD_ECO8A  (B7LYU4), E4PD_ECOBW  (C5A0J7), 
E4PD_ECODH  (B1XEL0), E4PD_ECOHS  (A8A467), E4PD_ECOK1  (A1AFB1), 
E4PD_ECOL5  (Q0TDS9), E4PD_ECOL6  (P0A9B7), E4PD_ECOLC  (B1IT76), 
E4PD_ECOLI  (P0A9B6), E4PD_ECOLU  (B7N7H3), E4PD_ECOSE  (B6I761), 
E4PD_ECOSM  (B1LDD2), E4PD_ECOUT  (Q1R7A6), E4PD_EDWI9  (C5BAU7), 
E4PD_ENT38  (A4WE72), E4PD_ERWT9  (B2VF24), E4PD_ESCF3  (B7LPD5), 
E4PD_KLEP3  (B5XUB7), E4PD_KLEP7  (A6TDT2), E4PD_PECAS  (Q6D086), 
E4PD_PECCP  (C6DFH8), E4PD_PHOLL  (Q7N7Z6), E4PD_PROMH  (B4EUH7), 
E4PD_PSYIN  (A1SVN9), E4PD_SALA4  (B5F5J5), E4PD_SALAR  (A9MRF0), 
E4PD_SALCH  (Q57K44), E4PD_SALDC  (B5FUI3), E4PD_SALEP  (B5QXJ7), 
E4PD_SALG2  (B5RE31), E4PD_SALHS  (B4THF4), E4PD_SALNS  (B4T5H2), 
E4PD_SALPA  (Q5PJI5), E4PD_SALPB  (A9N3Q6), E4PD_SALPC  (C0PY46), 
E4PD_SALPK  (B5BFN5), E4PD_SALSV  (B4TV39), E4PD_SALTI  (Q8XGA4), 
E4PD_SALTY  (Q7CPU5), E4PD_SHEAM  (A1S9A4), E4PD_SHEB2  (B8E5U5), 
E4PD_SHEDO  (Q12QA4), E4PD_SHEFN  (Q087Q7), E4PD_SHEHH  (B0TUC0), 
E4PD_SHELP  (A3QAX7), E4PD_SHEON  (Q8EIB2), E4PD_SHEPA  (A8H0M9), 
E4PD_SHEPC  (A4Y3R9), E4PD_SHEPW  (B8CU41), E4PD_SHESA  (A0L0K7), 
E4PD_SHESM  (Q0HM63), E4PD_SHESR  (Q0HRM3), E4PD_SHESW  (A1RN69), 
E4PD_SHIB3  (B2U0U3), E4PD_SHIBS  (Q31WI6), E4PD_SHIDS  (Q32BY7), 
E4PD_SHIF8  (Q0T0X3), E4PD_SHIFL  (P0A9B9), E4PD_SHISS  (Q3YXU5), 
E4PD_YERE8  (A1JPR1), E4PD_YERPA  (Q1CB62), E4PD_YERPE  (Q7CGS4), 
E4PD_YERPN  (Q1CEY2), E4PD_YERPS  (Q666Q0), G3P1_AGABI  (P32635), 
G3P1_ANAVT  (P34916), G3P1_BACCE  (Q4MQ58), G3P1_BACSU  (P09124), 
G3P1_CAEEL  (P04970), G3P1_CANGA  (Q6FPW3), G3P1_DROME  (P07486), 
G3P1_ECO57  (P0A9B4), G3P1_ECOL6  (P0A9B3), G3P1_ECOLI  (P0A9B2), 
G3P1_ESCF3  (B7LQ20), G3P1_ESCFE  (P0C8Z1), G3P1_ESCVU  (P24751), 
G3P1_GIAIN  (P53429), G3P1_GLORO  (O16027), G3P1_KLULA  (P17819), 
G3P1_KLUMA  (P84998), G3P1_METAC  (P58837), G3P1_METBF  (Q46AH5), 
G3P1_MUCCL  (Q9C136), G3P1_NOSS1  (P80506), G3P1_SALTI  (P0A1P1), 
G3P1_SALTY  (P0A1P0), G3P1_SCHPO  (P78958), G3P1_SHIFL  (P0A9B5), 
G3P1_STAAC  (Q5HHP5), G3P1_STAAM  (P0A036), G3P1_STAAN  (P99136), 
G3P1_STAAR  (Q6GIL8), G3P1_STAAS  (Q6GB58), G3P1_STAAU  (P0A038), 
G3P1_STAAW  (P0A037), G3P1_STAEQ  (Q5HQV4), G3P1_STAES  (Q8CPY5), 
G3P1_STRAW  (Q82IZ2), G3P1_SYNY3  (P49433), G3P1_TRIKO  (P17729), 
G3P1_YEAST  (P00360), G3P2_AGABI  (P32636), G3P2_ANAVT  (P34917), 
G3P2_BACSU  (O34425), G3P2_CAEBR  (P32809), G3P2_CAEEL  (P17329), 
G3P2_CANGA  (Q6FSM4), G3P2_DANRE  (Q5MJ86), G3P2_DROME  (P07487), 
G3P2_DROPS  (O44104), G3P2_DROSU  (O44105), G3P2_KLULA  (Q6CX23), 
G3P2_KLUMA  (Q01077), G3P2_METAC  (P58838), G3P2_METBF  (Q465K9), 
G3P2_MUCCL  (Q96UF2), G3P2_NOSS1  (P58554), G3P2_RHOSH  (P29272), 
G3P2_SCHPO  (O43026), G3P2_STAAC  (Q5HF86), G3P2_STAAM  (P64180), 
G3P2_STAAN  (P99067), G3P2_STAAR  (Q6GG19), G3P2_STAAS  (Q6G8N9), 
G3P2_STAAW  (P64181), G3P2_STAEQ  (Q5HNL7), G3P2_STAES  (Q8CNY0), 
G3P2_SYNY3  (P80505), G3P2_TRIKO  (P17730), G3P2_YEAST  (P00358), 
G3P3_ANAVT  (P34918), G3P3_CAEBR  (P32810), G3P3_CAEEL  (P17330), 
G3P3_ECO57  (P58072), G3P3_ECOLI  (P33898), G3P3_KLUMA  (P84999), 
G3P3_MUCCL  (Q96UF1), G3P3_NOSS1  (P58559), G3P3_YEAST  (P00359), 
G3P4_CAEEL  (P17331), G3PA1_ARATH (P25856), G3PA2_ARATH (Q9LPW0), 
G3PA_CHLRE  (P50362), G3PA_CHOCR  (P34919), G3PA_GRAGA  (P30724), 
G3PA_GUITH  (O09452), G3PA_MAIZE  (P09315), G3PA_PEA    (P12858), 
G3PA_SCEVA  (Q8VXQ9), G3PA_SINAL  (P09672), G3PA_SPIOL  (P19866), 
G3PA_TOBAC  (P09043), G3PB_ARATH  (P25857), G3PB_PEA    (P12859), 
G3PB_SPIOL  (P12860), G3PB_TOBAC  (P09044), G3PC1_ARATH (P25858), 
G3PC1_HORVU (P26517), G3PC1_MAIZE (P08735), G3PC1_ORYSJ (Q0J8A4), 
G3PC2_ARATH (Q9FX54), G3PC2_MAIZE (Q09054), G3PC2_ORYSJ (Q7FAH2), 
G3PC3_MAIZE (Q43247), G3PC3_ORYSJ (Q6K5G8), G3PC_ANTMA  (P25861), 
G3PC_CHLRE  (P49644), G3PC_CHOCR  (P34920), G3PC_CRAPL  (Q42671), 
G3PC_CUPNH  (P50321), G3PC_DIACA  (P34921), G3PC_GINBI  (Q39769), 
G3PC_GRAGA  (P54270), G3PC_LEIME  (Q01558), G3PC_MAGLI  (P26518), 
G3PC_MESCR  (P17878), G3PC_ORYSI  (A2YQT7), G3PC_PEA    (P34922), 
G3PC_PETCR  (P26519), G3PC_PETHY  (P26520), G3PC_PHYPA  (P34923), 
G3PC_PINSY  (P34924), G3PC_RANAC  (P26521), G3PC_SCEVA  (Q8VXQ8), 
G3PC_SINAL  (P04796), G3PC_TAXBA  (Q41595), G3PC_TOBAC  (P09094), 
G3PC_TRYBB  (P10097), G3PG_CRIFA  (O96423), G3PG_LEIME  (Q27890), 
G3PG_TRYBB  (P22512), G3PG_TRYCR  (P22513), G3PP1_ARATH (Q9SAJ6), 
G3PP2_ARATH (Q5E924), G3PP_CUPNH  (P50322), G3PT_BOVIN  (Q2KJE5), 
G3PT_HUMAN  (O14556), G3PT_MACFA  (Q4R3T1), G3PT_MOUSE  (Q64467), 
G3PT_RAT    (Q9ESV6), G3P_AERPE   (Q9YFS9), G3P_AJECA   (Q9HFX1), 
G3P_AMAMU   (P55071), G3P_AQUAE   (O67161), G3P_ARCFU   (O28542), 
G3P_ASHGO   (Q757I2), G3P_ASPNG   (Q12552), G3P_ASPOR   (Q9HGY7), 
G3P_ATRNU   (P34783), G3P_BACCO   (P15115), G3P_BACFR   (Q59199), 
G3P_BACMD   (P23722), G3P_BLUGH   (Q00640), G3P_BOLED   (Q00301), 
G3P_BORBU   (P46795), G3P_BORHE   (P46796), G3P_BOVIN   (P10096), 
G3P_BRUMA   (P48812), G3P_BUCAI   (P57384), G3P_BUCAP   (Q07234), 
G3P_BUCBP   (Q89AK1), G3P_CANAW   (Q92211), G3P_CANFA   (Q28259), 
G3P_CHICK   (P00356), G3P_CHLMU   (Q9PJN6), G3P_CHLPN   (Q9Z7T0), 
G3P_CHLT2   (B0B879), G3P_CHLTR   (P0CE13), G3P_CITFR   (P24748), 
G3P_CLAP2   (Q00584), G3P_CLOAB   (O52631), G3P_CLOPA   (Q59309), 
G3P_COCHE   (P29497), G3P_COCIM   (Q1DTF9), G3P_COCLU   (P28844), 
G3P_COCP7   (Q8J1H3), G3P_COLGL   (P35143), G3P_COLLI   (O57479), 
G3P_COLLN   (P54117), G3P_CORGL   (Q01651), G3P_COTJA   (Q05025), 
G3P_CRIGR   (P17244), G3P_CRYCU   (Q9Y796), G3P_CRYNB   (P0CN75), 
G3P_CRYNJ   (P0CN74), G3P_CRYPA   (P19089), G3P_DANRE   (Q5XJ10), 
G3P_DEBHA   (Q6BMK0), G3P_DICDI   (Q94469), G3P_DROHY   (Q01597), 
G3P_ECHMU   (Q27652), G3P_EMENI   (P20445), G3P_ESCHE   (P24750), 
G3P_FELCA   (Q9N2D5), G3P_GEOSE   (P00362), G3P_GLOMM   (Q4U3L0), 
G3P_HAEIN   (P44304), G3P_HALMA   (Q5V061), G3P_HALS3   (B0R2M2), 
G3P_HALSA   (Q9HSS7), G3P_HALVA   (Q48335), G3P_HELPJ   (Q9ZKT0), 
G3P_HELPY   (P55971), G3P_HOMAM   (P00357), G3P_HUMAN   (P04406), 
G3P_HYPAT   (P87197), G3P_HYPBU   (A2BLC6), G3P_JACOR   (P80534), 
G3P_KLEPN   (P24164), G3P_LACDT   (P55070), G3P_LENED   (Q9UR38), 
G3P_LYOSH   (Q92243), G3P_MASBA   (Q9N655), G3P_MESAU   (P51640), 
G3P_META3   (A6UUN9), G3P_METB6   (A7IB57), G3P_METBR   (P19314), 
G3P_METBU   (Q12XM4), G3P_METFE   (P10618), G3P_METFO   (P19315), 
G3P_METHJ   (Q2FNA2), G3P_METJA   (Q58546), G3P_METKA   (P58839), 
G3P_METM5   (A4FZL2), G3P_METM6   (A9A6M9), G3P_METM7   (A6VIW4), 
G3P_METMA   (Q8PTD3), G3P_METMP   (Q6M0E6), G3P_METS3   (A5ULT9), 
G3P_METS5   (A4YHA5), G3P_METST   (Q2NEN0), G3P_METTH   (O27090), 
G3P_METVS   (A6URW1), G3P_MONPU   (P53430), G3P_MOUSE   (P16858), 
G3P_MUSPF   (A3FKF7), G3P_MYCAV   (P94915), G3P_MYCBO   (P64179), 
G3P_MYCGE   (P47543), G3P_MYCLE   (P46713), G3P_MYCPN   (P75358), 
G3P_MYCS2   (A0QWW2), G3P_MYCTO   (P9WN82), G3P_MYCTU   (P9WN83), 
G3P_NATPD   (Q3IUT3), G3P_NEUCR   (P54118), G3P_OGAPD   (O59841), 
G3P_OMPOL   (Q8TFJ2), G3P_ONCMY   (O42259), G3P_ONCVO   (O01360), 
G3P_PANVR   (P56649), G3P_PARBA   (Q8X1X3), G3P_PELSI   (Q5R2J2), 
G3P_PHACH   (Q01982), G3P_PHANO   (Q9P8C0), G3P_PHARH   (O13507), 
G3P_PHYIN   (P26988), G3P_PICPA   (Q92263), G3P_PICTO   (Q6L125), 
G3P_PIG     (P00355), G3P_PODAS   (P32637), G3P_PONAB   (Q5RAB4), 
G3P_PSEAE   (P27726), G3P_PYRAB   (Q9V1P1), G3P_PYRAE   (Q8ZWK7), 
G3P_PYRAR   (A4WIW2), G3P_PYRCJ   (A3MTU1), G3P_PYRFU   (P61879), 
G3P_PYRHO   (O59494), G3P_PYRIL   (A1RV79), G3P_PYRNV   (B1YD06), 
G3P_PYRWO   (P61880), G3P_RABIT   (P46406), G3P_RALSO   (P52694), 
G3P_RAT     (P04797), G3P_RHIMI   (Q8NK47), G3P_SCHCO   (P32638), 
G3P_SCHMA   (P20287), G3P_SCLSC   (Q96US8), G3P_SERMA   (P24166), 
G3P_SEROD   (P24753), G3P_SHEEP   (Q28554), G3P_SHIBC   (I2BA89), 
G3P_SHIBL   (P0DJO7), G3P_SORMA   (Q8WZN0), G3P_SPECI   (Q4KYY3), 
G3P_STRAE   (P54226), G3P_STRAU   (Q59800), G3P_STREQ   (Q59906), 
G3P_STRP1   (P0C0G7), G3P_STRP3   (P0DB18), G3P_STRP6   (Q5XDW3), 
G3P_STRP8   (P68777), G3P_STRPQ   (P0DB19), G3P_STRPY   (P0C0G6), 
G3P_SULAC   (Q4J940), G3P_SULIA   (C3N6F0), G3P_SULIK   (C4KHW5), 
G3P_SULIL   (C3MQN0), G3P_SULIM   (C3MWN0), G3P_SULIN   (C3NGT6), 
G3P_SULIY   (C3NEV8), G3P_SULSO   (P39460), G3P_SULTO   (Q971K2), 
G3P_THEAC   (Q9HJ69), G3P_THEAQ   (P00361), G3P_THEKO   (Q5JHB5), 
G3P_THEMA   (P17721), G3P_THEON   (B6YUU0), G3P_THESM   (C6A312), 
G3P_THEVO   (Q97BJ8), G3P_TREPA   (O83816), G3P_USTMA   (P09317), 
G3P_WICCF   (Q9UVC0), G3P_XANFL   (P51009), G3P_XENLA   (P51469), 
G3P_YARLI   (Q6CCU7), G3P_ZYGRO   (P08439), G3P_ZYMMO   (P09316)
» More

UniProtKB/Swiss-Prot
False negative sequences
25 sequences

E4PD_AERHH  (A0KGD2), E4PD_AERS4  (A4SRF2), E4PD_ALISL  (B6EMW1), 
E4PD_ALTMD  (B4RWC5), E4PD_COLP3  (Q47XD5), E4PD_IDILO  (Q5QVL6), 
E4PD_PHOPR  (Q6LMN0), E4PD_PSEA6  (Q15QK3), E4PD_PSEHT  (Q3ILL8), 
E4PD_TOLAT  (C4L9J3), E4PD_VIBC3  (A5F9G1), E4PD_VIBCB  (A7MTQ2), 
E4PD_VIBCH  (P0C6C2), E4PD_VIBF1  (Q5E7R0), E4PD_VIBFM  (B5F9T4), 
E4PD_VIBPA  (Q87LL0), E4PD_VIBVU  (Q8DCA1), E4PD_VIBVY  (Q7MHL0), 
G3P_ENTAE   (P24163), G3P_LACDE   (O32755), G3P_LACLA   (P52987), 
G3P_MELGA   (O57672), G3P_METMJ   (A3CYG8), G3P_PLESA   (Q9UW96), 
G3P_STRCO   (Q9Z518)
» More

UniProtKB/Swiss-Prot
'Partial' sequences
8 sequences

G3P2_BACCE  (P83077), G3PB_POPEU  (P84544), G3PC2_HORVU (P08477), 
G3PC_PSEMZ  (P85954), G3PT_MESAU  (P86211), G3P_CAVPO   (P70685), 
G3P_NAEFO   (P83601), PS5_PINST   (P84721)
» More

UniProtKB/Swiss-Prot
False positive sequences
10 sequences

BLAA_STRCI  (P33651), DDB1_DROME  (Q9XYZ5), ERYA1_SACER (Q03131), 
LR16A_MOUSE (Q6EDY6), MATK_VACFA  (Q6E4Q3), PGLR1_COLLN (Q00446), 
SIBD_DICDI  (Q54JA4), SIK3_DANRE  (Q6NSM8), TGFB3_CHICK (P16047), 
XYLT_DROME  (Q7KVA1)
» More

PDB
[Detailed view]
71 PDB

1A7K; 1B7G; 1CER; 1CF2; 1CRW; 1DBV; 1DC3; 1DC4; 1DC5; 1DC6; 1GAD; 1GAE; 1GD1; 1GPD; 1GYP; 1GYQ; 1HDG; 1I32; 1I33; 1IHX; 1IHY; 1JN0; 1K3T; 1ML3; 1NBO; 1QXS; 1RM3; 1RM4; 1RM5; 1S7C; 1SZJ; 1U8F; 1ZNQ; 2CZC; 2DBV; 2EP7; 2GD1; 2HKI; 2I5P; 2PKQ; 2PKR; 2X0N; 2X5J; 2XF8; 2YYY; 3CMC; 3DBV; 3DMT; 3E5R; 3E6A; 3GPD; 3H9E; 3HJA; 3IDS; 3K2B; 3K73; 3L6O; 3LC1; 3LC2; 3LC7; 3LVF; 3PFW; 3PYM; 3QV1; 3RVD; 3V1Y; 3VAZ; 4DBV; 4GPD; 4IQ8; 4K9D
» More

View entry in original PROSITE format
View entry in raw text format (no links)
Direct ScanProsite submission