Entry: PS00071

General information about the entry

Entry name [info] GAPDH
Accession [info] PS00071
Entry type [info] PATTERN
Date [info] APR-1990 (CREATED); DEC-2004 (DATA UPDATE); MAY-2016 (INFO UPDATE).
PROSITE Doc. [info] PDOC00069
Associated ProRule [info] PRU10009

Name and characterization of the entry

Description [info] Glyceraldehyde 3-phosphate dehydrogenase active site.
Pattern [info]
[ASV]-S-C-[NT]-T-{S}-x-[LIM].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2016_05 which contains 551'193 sequence entries.


Total number of hits 402 in 402 different sequences
Number of true positive hits 392 in 392 different sequences
Number of 'unknown' hits 0
Number of false positive hits 10 in 10 different sequences
Number of false negative sequences 25
Number of 'partial' sequences 8
Precision (true positives / (true positives + false positives)) 97.51 %
Recall (true positives / (true positives + false negatives)) 94.00 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] active_site at position 3
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
392 sequences

E4PD_CITK8  (A8APE1    ), E4PD_CROS8  (A7MJQ2    ), E4PD_ECO24  (A7ZR35    ), 
E4PD_ECO27  (B7UHW9    ), E4PD_ECO45  (B7MMA9    ), E4PD_ECO55  (B7LFI3    ), 
E4PD_ECO57  (P0A9B8    ), E4PD_ECO5E  (B5YQB9    ), E4PD_ECO7I  (B7NHY6    ), 
E4PD_ECO81  (B7MZM0    ), E4PD_ECO8A  (B7LYU4    ), E4PD_ECOBW  (C5A0J7    ), 
E4PD_ECODH  (B1XEL0    ), E4PD_ECOHS  (A8A467    ), E4PD_ECOK1  (A1AFB1    ), 
E4PD_ECOL5  (Q0TDS9    ), E4PD_ECOL6  (P0A9B7    ), E4PD_ECOLC  (B1IT76    ), 
E4PD_ECOLI  (P0A9B6    ), E4PD_ECOLU  (B7N7H3    ), E4PD_ECOSE  (B6I761    ), 
E4PD_ECOSM  (B1LDD2    ), E4PD_ECOUT  (Q1R7A6    ), E4PD_EDWI9  (C5BAU7    ), 
E4PD_ENT38  (A4WE72    ), E4PD_ERWT9  (B2VF24    ), E4PD_ESCF3  (B7LPD5    ), 
E4PD_KLEP3  (B5XUB7    ), E4PD_KLEP7  (A6TDT2    ), E4PD_PECAS  (Q6D086    ), 
E4PD_PECCP  (C6DFH8    ), E4PD_PHOLL  (Q7N7Z6    ), E4PD_PROMH  (B4EUH7    ), 
E4PD_PSYIN  (A1SVN9    ), E4PD_SALA4  (B5F5J5    ), E4PD_SALAR  (A9MRF0    ), 
E4PD_SALCH  (Q57K44    ), E4PD_SALDC  (B5FUI3    ), E4PD_SALEP  (B5QXJ7    ), 
E4PD_SALG2  (B5RE31    ), E4PD_SALHS  (B4THF4    ), E4PD_SALNS  (B4T5H2    ), 
E4PD_SALPA  (Q5PJI5    ), E4PD_SALPB  (A9N3Q6    ), E4PD_SALPC  (C0PY46    ), 
E4PD_SALPK  (B5BFN5    ), E4PD_SALSV  (B4TV39    ), E4PD_SALTI  (Q8XGA4    ), 
E4PD_SALTY  (Q7CPU5    ), E4PD_SHEAM  (A1S9A4    ), E4PD_SHEB2  (B8E5U5    ), 
E4PD_SHEDO  (Q12QA4    ), E4PD_SHEFN  (Q087Q7    ), E4PD_SHEHH  (B0TUC0    ), 
E4PD_SHELP  (A3QAX7    ), E4PD_SHEON  (Q8EIB2    ), E4PD_SHEPA  (A8H0M9    ), 
E4PD_SHEPC  (A4Y3R9    ), E4PD_SHEPW  (B8CU41    ), E4PD_SHESA  (A0L0K7    ), 
E4PD_SHESM  (Q0HM63    ), E4PD_SHESR  (Q0HRM3    ), E4PD_SHESW  (A1RN69    ), 
E4PD_SHIB3  (B2U0U3    ), E4PD_SHIBS  (Q31WI6    ), E4PD_SHIDS  (Q32BY7    ), 
E4PD_SHIF8  (Q0T0X3    ), E4PD_SHIFL  (P0A9B9    ), E4PD_SHISS  (Q3YXU5    ), 
E4PD_YERE8  (A1JPR1    ), E4PD_YERPA  (Q1CB62    ), E4PD_YERPE  (Q7CGS4    ), 
E4PD_YERPN  (Q1CEY2    ), E4PD_YERPS  (Q666Q0    ), G3P1_AGABI  (P32635    ), 
G3P1_ANAVT  (P34916    ), G3P1_BACCE  (Q4MQ58    ), G3P1_BACSU  (P09124    ), 
G3P1_CAEEL  (P04970    ), G3P1_CANGA  (Q6FPW3    ), G3P1_DROME  (P07486    ), 
G3P1_ECO57  (P0A9B4    ), G3P1_ECOLI  (P0A9B2    ), G3P1_GIAIN  (P53429    ), 
G3P1_GLORO  (O16027    ), G3P1_KLULA  (P17819    ), G3P1_KLUMA  (P84998    ), 
G3P1_METAC  (P58837    ), G3P1_METBF  (Q46AH5    ), G3P1_MUCCL  (Q9C136    ), 
G3P1_NOSS1  (P80506    ), G3P1_SCHPO  (P78958    ), G3P1_STAAC  (Q5HHP5    ), 
G3P1_STAAM  (P0A036    ), G3P1_STAAN  (P99136    ), G3P1_STAAR  (Q6GIL8    ), 
G3P1_STAAS  (Q6GB58    ), G3P1_STAAW  (P0A037    ), G3P1_STAEQ  (Q5HQV4    ), 
G3P1_STAES  (Q8CPY5    ), G3P1_STRAE  (P54226    ), G3P1_STRAW  (Q82IZ2    ), 
G3P1_SYNY3  (P49433    ), G3P1_TRIKO  (P17729    ), G3P1_YEAST  (P00360    ), 
G3P2_AGABI  (P32636    ), G3P2_ANAVT  (P34917    ), G3P2_BACSU  (O34425    ), 
G3P2_CAEBR  (P32809    ), G3P2_CAEEL  (P17329    ), G3P2_CANGA  (Q6FSM4    ), 
G3P2_DANRE  (Q5MJ86    ), G3P2_DROME  (P07487    ), G3P2_DROPS  (O44104    ), 
G3P2_DROSU  (O44105    ), G3P2_ECO57  (P58072    ), G3P2_ECOLI  (P33898    ), 
G3P2_KLULA  (Q6CX23    ), G3P2_KLUMA  (Q01077    ), G3P2_METAC  (P58838    ), 
G3P2_METBF  (Q465K9    ), G3P2_MUCCL  (Q96UF2    ), G3P2_NOSS1  (P58554    ), 
G3P2_SCHPO  (O43026    ), G3P2_STAAC  (Q5HF86    ), G3P2_STAAM  (P64180    ), 
G3P2_STAAN  (P99067    ), G3P2_STAAR  (Q6GG19    ), G3P2_STAAS  (Q6G8N9    ), 
G3P2_STAAW  (P64181    ), G3P2_STAEQ  (Q5HNL7    ), G3P2_STAES  (Q8CNY0    ), 
G3P2_STRAE  (E3VWI2    ), G3P2_SYNY3  (P80505    ), G3P2_TRIKO  (P17730    ), 
G3P2_YEAST  (P00358    ), G3P3_ANAVT  (P34918    ), G3P3_CAEBR  (P32810    ), 
G3P3_CAEEL  (P17330    ), G3P3_KLUMA  (P84999    ), G3P3_MUCCL  (Q96UF1    ), 
G3P3_NOSS1  (P58559    ), G3P3_YEAST  (P00359    ), G3P4_CAEEL  (P17331    ), 
G3PA1_ARATH (P25856    ), G3PA2_ARATH (Q9LPW0    ), G3PA_CHLRE  (P50362    ), 
G3PA_CHOCR  (P34919    ), G3PA_GRAGA  (P30724    ), G3PA_GUITH  (O09452    ), 
G3PA_MAIZE  (P09315    ), G3PA_PEA    (P12858    ), G3PA_SCEVA  (Q8VXQ9    ), 
G3PA_SINAL  (P09672    ), G3PA_SPIOL  (P19866    ), G3PA_TOBAC  (P09043    ), 
G3PB_ARATH  (P25857    ), G3PB_PEA    (P12859    ), G3PB_SPIOL  (P12860    ), 
G3PB_TOBAC  (P09044    ), G3PC1_ARATH (P25858    ), G3PC1_HORVU (P26517    ), 
G3PC1_MAIZE (P08735    ), G3PC1_ORYSJ (Q0J8A4    ), G3PC2_ARATH (Q9FX54    ), 
G3PC2_MAIZE (Q09054    ), G3PC2_ORYSJ (Q7FAH2    ), G3PC3_MAIZE (Q43247    ), 
G3PC3_ORYSJ (Q6K5G8    ), G3PC_ANTMA  (P25861    ), G3PC_CHLRE  (P49644    ), 
G3PC_CHOCR  (P34920    ), G3PC_CRAPL  (Q42671    ), G3PC_CUPNH  (P50321    ), 
G3PC_DIACA  (P34921    ), G3PC_GINBI  (Q39769    ), G3PC_GRAGA  (P54270    ), 
G3PC_LEIME  (Q01558    ), G3PC_MAGLI  (P26518    ), G3PC_MESCR  (P17878    ), 
G3PC_ORYSI  (A2YQT7    ), G3PC_PEA    (P34922    ), G3PC_PETCR  (P26519    ), 
G3PC_PETHY  (P26520    ), G3PC_PHYPA  (P34923    ), G3PC_PINSY  (P34924    ), 
G3PC_RANAC  (P26521    ), G3PC_SCEVA  (Q8VXQ8    ), G3PC_SINAL  (P04796    ), 
G3PC_TAXBA  (Q41595    ), G3PC_TOBAC  (P09094    ), G3PC_TRYBB  (P10097    ), 
G3PG_CRIFA  (O96423    ), G3PG_LEIME  (Q27890    ), G3PG_TRYBB  (P22512    ), 
G3PG_TRYCR  (P22513    ), G3PP1_ARATH (Q9SAJ6    ), G3PP2_ARATH (Q5E924    ), 
G3PP_CUPNH  (P50322    ), G3PT_BOVIN  (Q2KJE5    ), G3PT_HUMAN  (O14556    ), 
G3PT_MACFA  (Q4R3T1    ), G3PT_MOUSE  (Q64467    ), G3PT_RAT    (Q9ESV6    ), 
G3P_AERPE   (Q9YFS9    ), G3P_AJECA   (Q9HFX1    ), G3P_AMAMU   (P55071    ), 
G3P_AQUAE   (O67161    ), G3P_ARCFU   (O28542    ), G3P_ASHGO   (Q757I2    ), 
G3P_ASPNG   (Q12552    ), G3P_ASPOR   (Q9HGY7    ), G3P_ATRNU   (P34783    ), 
G3P_BACCO   (P15115    ), G3P_BACFR   (Q59199    ), G3P_BACMD   (P23722    ), 
G3P_BLUGH   (Q00640    ), G3P_BOLED   (Q00301    ), G3P_BORBU   (P46795    ), 
G3P_BORHE   (P46796    ), G3P_BOVIN   (P10096    ), G3P_BRUMA   (P48812    ), 
G3P_BUCAI   (P57384    ), G3P_BUCAP   (Q07234    ), G3P_BUCBP   (Q89AK1    ), 
G3P_CANAW   (Q92211    ), G3P_CANLF   (Q28259    ), G3P_CHICK   (P00356    ), 
G3P_CHLMU   (Q9PJN6    ), G3P_CHLPN   (Q9Z7T0    ), G3P_CHLT2   (B0B879    ), 
G3P_CHLTR   (P0CE13    ), G3P_CITFR   (P24748    ), G3P_CLAP2   (Q00584    ), 
G3P_CLOAB   (O52631    ), G3P_CLOPA   (Q59309    ), G3P_COCHE   (P29497    ), 
G3P_COCIM   (Q1DTF9    ), G3P_COCLU   (P28844    ), G3P_COCP7   (Q8J1H3    ), 
G3P_COLGL   (P35143    ), G3P_COLLI   (O57479    ), G3P_COLLN   (P54117    ), 
G3P_CORGL   (Q01651    ), G3P_COTJA   (Q05025    ), G3P_CRIGR   (P17244    ), 
G3P_CRYCU   (Q9Y796    ), G3P_CRYNB   (P0CN75    ), G3P_CRYNJ   (P0CN74    ), 
G3P_CRYPA   (P19089    ), G3P_DANRE   (Q5XJ10    ), G3P_DEBHA   (Q6BMK0    ), 
G3P_DICDI   (Q94469    ), G3P_DROHY   (Q01597    ), G3P_ECHMU   (Q27652    ), 
G3P_ECOL6   (P0A9B3    ), G3P_EMENI   (P20445    ), G3P_ESCF3   (B7LQ20    ), 
G3P_ESCFE   (P0C8Z1    ), G3P_ESCHE   (P24750    ), G3P_ESCVU   (P24751    ), 
G3P_FELCA   (Q9N2D5    ), G3P_GEOSE   (P00362    ), G3P_GLOMM   (Q4U3L0    ), 
G3P_HAEIN   (P44304    ), G3P_HALMA   (Q5V061    ), G3P_HALS3   (B0R2M2    ), 
G3P_HALSA   (Q9HSS7    ), G3P_HALVA   (Q48335    ), G3P_HELPJ   (Q9ZKT0    ), 
G3P_HELPY   (P55971    ), G3P_HOMAM   (P00357    ), G3P_HUMAN   (P04406    ), 
G3P_HYPAT   (P87197    ), G3P_HYPBU   (A2BLC6    ), G3P_JACOR   (P80534    ), 
G3P_KLEPN   (P24164    ), G3P_LACDT   (P55070    ), G3P_LENED   (Q9UR38    ), 
G3P_LYOSH   (Q92243    ), G3P_MASBA   (Q9N655    ), G3P_MESAU   (P51640    ), 
G3P_META3   (A6UUN9    ), G3P_METB6   (A7IB57    ), G3P_METBR   (P19314    ), 
G3P_METBU   (Q12XM4    ), G3P_METFE   (P10618    ), G3P_METFO   (P19315    ), 
G3P_METHJ   (Q2FNA2    ), G3P_METJA   (Q58546    ), G3P_METKA   (P58839    ), 
G3P_METM5   (A4FZL2    ), G3P_METM6   (A9A6M9    ), G3P_METM7   (A6VIW4    ), 
G3P_METMA   (Q8PTD3    ), G3P_METMP   (Q6M0E6    ), G3P_METS3   (A5ULT9    ), 
G3P_METS5   (A4YHA5    ), G3P_METST   (Q2NEN0    ), G3P_METTH   (O27090    ), 
G3P_METVS   (A6URW1    ), G3P_MONPU   (P53430    ), G3P_MOUSE   (P16858    ), 
G3P_MUSPF   (A3FKF7    ), G3P_MYCAV   (P94915    ), G3P_MYCBO   (P64179    ), 
G3P_MYCGE   (P47543    ), G3P_MYCLE   (P46713    ), G3P_MYCPN   (P75358    ), 
G3P_MYCS2   (A0QWW2    ), G3P_MYCTO   (P9WN82    ), G3P_MYCTU   (P9WN83    ), 
G3P_NATPD   (Q3IUT3    ), G3P_NEUCR   (P54118    ), G3P_OGAPD   (O59841    ), 
G3P_OMPOL   (Q8TFJ2    ), G3P_ONCMY   (O42259    ), G3P_ONCVO   (O01360    ), 
G3P_PANVR   (P56649    ), G3P_PARBA   (Q8X1X3    ), G3P_PELSI   (Q5R2J2    ), 
G3P_PHACH   (Q01982    ), G3P_PHANO   (Q9P8C0    ), G3P_PHARH   (O13507    ), 
G3P_PHYIN   (P26988    ), G3P_PICPA   (Q92263    ), G3P_PICTO   (Q6L125    ), 
G3P_PIG     (P00355    ), G3P_PODAS   (P32637    ), G3P_PONAB   (Q5RAB4    ), 
G3P_PSEAE   (P27726    ), G3P_PYRAB   (Q9V1P1    ), G3P_PYRAE   (Q8ZWK7    ), 
G3P_PYRAR   (A4WIW2    ), G3P_PYRCJ   (A3MTU1    ), G3P_PYRFU   (P61879    ), 
G3P_PYRHO   (O59494    ), G3P_PYRIL   (A1RV79    ), G3P_PYRNV   (B1YD06    ), 
G3P_PYRWO   (P61880    ), G3P_RABIT   (P46406    ), G3P_RALSO   (P52694    ), 
G3P_RAT     (P04797    ), G3P_RHIMI   (Q8NK47    ), G3P_RHOSH   (P29272    ), 
G3P_SALTI   (P0A1P1    ), G3P_SALTY   (P0A1P0    ), G3P_SCHCO   (P32638    ), 
G3P_SCHMA   (P20287    ), G3P_SCLSC   (Q96US8    ), G3P_SERMA   (P24166    ), 
G3P_SEROD   (P24753    ), G3P_SHEEP   (Q28554    ), G3P_SHIBC   (I2BA89    ), 
G3P_SHIBL   (P0DJO7    ), G3P_SHIFL   (P0A9B5    ), G3P_SORMA   (Q8WZN0    ), 
G3P_SPECI   (Q4KYY3    ), G3P_STAAU   (P0A038    ), G3P_STRAU   (Q59800    ), 
G3P_STREQ   (Q59906    ), G3P_STRP1   (P0C0G7    ), G3P_STRP3   (P0DB18    ), 
G3P_STRP6   (Q5XDW3    ), G3P_STRP8   (P68777    ), G3P_STRPQ   (P0DB19    ), 
G3P_STRPY   (P0C0G6    ), G3P_SULAC   (Q4J940    ), G3P_SULIA   (C3N6F0    ), 
G3P_SULIK   (C4KHW5    ), G3P_SULIL   (C3MQN0    ), G3P_SULIM   (C3MWN0    ), 
G3P_SULIN   (C3NGT6    ), G3P_SULIY   (C3NEV8    ), G3P_SULSO   (P39460    ), 
G3P_SULTO   (Q971K2    ), G3P_THEAC   (Q9HJ69    ), G3P_THEAQ   (P00361    ), 
G3P_THEKO   (Q5JHB5    ), G3P_THEMA   (P17721    ), G3P_THEON   (B6YUU0    ), 
G3P_THESM   (C6A312    ), G3P_THEVO   (Q97BJ8    ), G3P_TREPA   (O83816    ), 
G3P_USTMA   (P09317    ), G3P_WICCF   (Q9UVC0    ), G3P_XANFL   (P51009    ), 
G3P_XENLA   (P51469    ), G3P_YARLI   (Q6CCU7    ), G3P_ZYGRO   (P08439    ), 
G3P_ZYMMO   (P09316    ), GAP2_PSEAB  (Q02PG5    )
» more

UniProtKB/Swiss-Prot
False negative sequences
25 sequences

E4PD_AERHH  (A0KGD2    ), E4PD_AERS4  (A4SRF2    ), E4PD_ALISL  (B6EMW1    ), 
E4PD_ALTMD  (B4RWC5    ), E4PD_COLP3  (Q47XD5    ), E4PD_IDILO  (Q5QVL6    ), 
E4PD_PHOPR  (Q6LMN0    ), E4PD_PSEA6  (Q15QK3    ), E4PD_PSEHT  (Q3ILL8    ), 
E4PD_TOLAT  (C4L9J3    ), E4PD_VIBC3  (A5F9G1    ), E4PD_VIBCB  (A7MTQ2    ), 
E4PD_VIBCH  (P0C6C2    ), E4PD_VIBF1  (Q5E7R0    ), E4PD_VIBFM  (B5F9T4    ), 
E4PD_VIBPA  (Q87LL0    ), E4PD_VIBVU  (Q8DCA1    ), E4PD_VIBVY  (Q7MHL0    ), 
G3P_ENTAE   (P24163    ), G3P_LACDE   (O32755    ), G3P_LACLA   (P52987    ), 
G3P_MELGA   (O57672    ), G3P_METMJ   (A3CYG8    ), G3P_PLESA   (Q9UW96    ), 
G3P_STRCO   (Q9Z518    )
» more

UniProtKB/Swiss-Prot
'Partial' sequences
8 sequences

G3P2_BACCE  (P83077    ), G3PB_POPEU  (P84544    ), G3PC2_HORVU (P08477    ), 
G3PC_PSEMZ  (P85954    ), G3PT_MESAU  (P86211    ), G3P_CAVPO   (P70685    ), 
G3P_NAEFO   (P83601    ), PS5_PINST   (P84721    )
» more

UniProtKB/Swiss-Prot
False positive sequences
10 sequences

BLAA_STRCI  (P33651    ), CARL1_MOUSE (Q6EDY6    ), DDB1_DROME  (Q9XYZ5    ), 
ERYA1_SACER (Q03131    ), MATK_VACFA  (Q6E4Q3    ), PGLR1_COLLN (Q00446    ), 
SIBD_DICDI  (Q54JA4    ), SIK3_DANRE  (Q6NSM8    ), TGFB3_CHICK (P16047    ), 
XYLT_DROME  (Q7KVA1    )
» more

PDB
[Detailed view]
75 PDB

1A7K; 1B7G; 1CER; 1CF2; 1CRW; 1DBV; 1DC3; 1DC4; 1DC5; 1DC6; 1GAD; 1GAE; 1GD1; 1GPD; 1GYP; 1GYQ; 1HDG; 1I32; 1I33; 1IHX; 1IHY; 1JN0; 1K3T; 1ML3; 1NBO; 1QXS; 1RM3; 1RM4; 1RM5; 1S7C; 1SZJ; 1U8F; 1ZNQ; 2CZC; 2DBV; 2EP7; 2GD1; 2HKI; 2I5P; 2PKQ; 2PKR; 2X0N; 2X5J; 2XF8; 2YYY; 3CMC; 3DBV; 3DMT; 3E5R; 3E6A; 3GPD; 3H9E; 3HJA; 3IDS; 3K2B; 3K73; 3L6O; 3LC1; 3LC2; 3LC7; 3LVF; 3PFW; 3PYM; 3QV1; 3RVD; 3V1Y; 3VAZ; 4DBV; 4GPD; 4IQ8; 4K9D; 4O59; 4O63; 4WNC; 4WNI
» more

View entry in original PROSITE format
View entry in raw text format (no links)
Direct ScanProsite submission