Entry: PS00079

General information about the entry

Entry name [info] MULTICOPPER_OXIDASE1
Accession [info] PS00079
Entry type [info] PATTERN
Date [info] APR-1990 (CREATED); APR-2006 (DATA UPDATE); MAY-2015 (INFO UPDATE).
PROSITE Doc. [info] PDOC00076

Name and characterization of the entry

Description [info] Multicopper oxidases signature 1.
Pattern [info]
G-x-[FYW]-x-[LIVMFYW]-x-[CST]-x-{PR}-{K}-x(2)-{S}-x-{LFH}-G-[LM]-x(3)-
[LIVMFYW].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2015_07 which contains 548'872 sequence entries.


Total number of hits 200 in 150 different sequences
Number of true positive hits 160 in 110 different sequences
Number of 'unknown' hits 0
Number of false positive hits 40 in 40 different sequences
Number of false negative sequences 12
Number of 'partial' sequences 7
Precision (true positives / (true positives + false positives)) 80.00 %
Recall (true positives / (true positives + false negatives)) 93.02 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 3
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
110 sequences

ASO_CUCMA   (P24792), ASO_CUCPM   (P37064), ASO_CUCSA   (P14133), 
ASO_TOBAC   (Q40588), AURB_CHLAA  (P27197), CERU_HUMAN  (P00450), 
CERU_MOUSE  (Q61147), CERU_RAT    (P13635), CERU_SHEEP  (Q9XT27), 
COPA_PSESM  (P59571), COPA_PSEUB  (P12374), FA5V_OXYMI  (Q58L90), 
FA5V_OXYSU  (Q58L91), FA5V_PSETE  (Q7SZN0), FA5_BOVIN   (Q28107), 
FA5_HUMAN   (P12259), FA5_MOUSE   (O88783), FA5_PIG     (Q9GLP1), 
FA5_PSETE   (Q593B6), FA8_CANFA   (O18806), FA8_HUMAN   (P00451), 
FA8_MOUSE   (Q06194), FA8_PIG     (P12263), FET3_CANAX  (P78591), 
FET3_CANGA  (Q96WT3), FET3_KLULA  (Q6CII3), FET3_YEAST  (P38993), 
FET5_YEAST  (P43561), FIO1_SCHPO  (Q09920), GMC1_YEAST  (Q04399), 
HEPHL_ACRMI (B3EWZ9), HEPH_HUMAN  (Q9BQS7), HEPH_MOUSE  (Q9Z0Z4), 
HEPH_RAT    (Q920H8), HPHL1_HUMAN (Q6MZM0), HPHL1_MOUSE (Q3V1H3), 
LAC10_ARATH (Q6ID18), LAC10_ORYSJ (Q10ND7), LAC11_ARATH (Q8VZA1), 
LAC11_ORYSJ (Q0DHL5), LAC12_ARATH (Q9FLB5), LAC12_ORYSJ (Q0DHL2), 
LAC13_ARATH (Q9LYQ2), LAC14_ARATH (Q9FY79), LAC15_ARATH (Q84J37), 
LAC15_ORYSJ (Q339K6), LAC16_ARATH (Q1PDH6), LAC16_ORYSJ (Q7XE50), 
LAC17_ARATH (Q9FJD5), LAC17_ORYSJ (Q2RBK2), LAC18_ORYSI (A2XCN6), 
LAC18_ORYSJ (Q53LU4), LAC19_ORYSI (A2Y9C5), LAC19_ORYSJ (Q2R0L2), 
LAC1_AGABI  (Q12541), LAC1_ARATH  (Q9LMS3), LAC1_BOTFU  (Q12570), 
LAC1_CRYPA  (Q03966), LAC1_MELAO  (Q70KY3), LAC1_NEUCR  (P06811), 
LAC1_ORYSJ  (Q5ZCW1), LAC1_PHLRA  (Q01679), LAC1_PLEOS  (Q12729), 
LAC1_PYCCI  (O59896), LAC1_THACU  (P56193), LAC1_TRAHI  (Q02497), 
LAC1_TRAMX  (D0VWU3), LAC1_TRAVI  (Q99044), LAC20_ORYSI (A2Y9C2), 
LAC20_ORYSJ (Q2R0L0), LAC21_ORYSJ (Q2QZ80), LAC22_ORYSJ (Q0IQU1), 
LAC23_ORYSJ (Q2QYS3), LAC2_AGABI  (Q12542), LAC2_ARATH  (O81081), 
LAC2_BOTFU  (Q96WM9), LAC2_ORYSJ  (Q8RYM9), LAC2_PLEOS  (Q12739), 
LAC2_PODAS  (P78722), LAC2_THACU  (Q02075), LAC2_TRAVE  (Q12718), 
LAC2_TRAVI  (Q99046), LAC3_ARATH  (Q56YT0), LAC3_BOTFU  (Q96UM2), 
LAC3_ORYSJ  (Q941X2), LAC3_THACU  (Q02079), LAC3_TRAVI  (Q99049), 
LAC4_ARATH  (O80434), LAC4_ORYSJ  (Q5N9X2), LAC4_TRAVE  (Q12719), 
LAC4_TRAVI  (Q99055), LAC5_ARATH  (Q9SIY8), LAC5_ORYSJ  (Q5N9W4), 
LAC5_TRAVE  (Q12717), LAC5_TRAVI  (Q99056), LAC6_ARATH  (Q9ZPY2), 
LAC6_ORYSJ  (Q5N7A3), LAC7_ORYSJ  (Q5N7B4), LAC9_ORYSJ  (Q6Z8L2), 
MCO_STAAR   (Q6GIX3), MCO_STAAU   (Q69HT9), MCO_STAES   (Q8CQF6), 
MCO_STAHJ   (Q4LAB0), MMCO_MYCTU  (I6WZK7), PCOA_ECOLX  (Q47452), 
PHSA_STRAT  (Q53692), RUS1_ACIFR  (P23742), RUS2_ACIFR  (P0C918), 
RUS_ACIF2   (B7JAQ0), SOXE_SULAC  (Q53765)
» More

UniProtKB/Swiss-Prot
False negative sequences
12 sequences

LAC14_ORYSJ (Q69L99), LAC1_EMENI  (P17489), LAC24_ORYSJ (Q2QUN2), 
LAC25_ORYSJ (Q0IP28), LAC4_THACU  (Q02081), LAC7_ARATH  (Q9SR40), 
LAC8_ARATH  (Q9LFD2), LAC8_ORYSJ  (Q0JHP8), LAC9_ARATH  (Q9LFD1), 
LACC_HALVD  (D4GPK6), LPR1_ARATH  (F4I4K5), LPR2_ARATH  (Q949X9)
» More

UniProtKB/Swiss-Prot
'Partial' sequences
7 sequences

LAC1B_CERUI (P85308), LAC1_GALSP  (P86351), LAC2D_CERUI (P85430), 
LAC2_CERUI  (P85149), LACC1_CERUI (P86328), LACC2_CERUI (P86327), 
MCOL1_ZINVI (P85414)
» More

UniProtKB/Swiss-Prot
False positive sequences
40 sequences

ACCD_CALFG  (Q7YIX5), AL15_ASPFU  (O60022), ATE_GRABC   (Q0BTF8), 
CALI_BOVIN  (Q28068), CALI_HUMAN  (Q13939), CALI_MOUSE  (Q8CDE2), 
CALI_RAT    (Q5XI58), DPO3A_STAEQ (Q5HNK2), DPO3A_STAES (Q8CNX0), 
DPOL1_SULOH (O50607), EXG1_YEAST  (P23776), EXG_SACU7   (Q876J3), 
FPOH_METAC  (Q8TQP1), GPR98_DANRE (Q6JAN0), HYAL4_HUMAN (Q2M3T9), 
HYAL_CONCN  (I0CME7), IMCL2_ORYSJ (Q5VNW5), MGLA_CLOTE  (Q896Y2), 
NDVA_RHOP2  (Q2J0F4), NDVA_RHOPS  (Q13BH6), NUD17_ARATH (Q9ZU95), 
PEPT_PASMU  (Q9CP05), PTTBC_BACSU (P39794), RIR1_TRYBB  (O15909), 
S15A4_BOVIN (A6QQL0), S15A4_HUMAN (Q8N697), S15A4_MOUSE (Q91W98), 
S15A4_RAT   (O09014), S15A4_XENLA (Q68F72), SIM2_MOUSE  (Q61079), 
THII_COXBU  (Q83CD9), UT1_CAPHI   (D3INW7), UT1_HUMAN   (Q13336), 
UT1_MOUSE   (Q8VHL0), UT1_RAT     (P97689), UT1_SHEEP   (C5MK33), 
UT2_HUMAN   (Q15849), UT2_MOUSE   (Q8R4T9), UT2_RAT     (Q62668), 
Y3934_DICDI (Q54B29)
» More

PDB
[Detailed view]
39 PDB

1A3Z; 1A8Z; 1AOZ; 1ASO; 1ASP; 1ASQ; 1CUR; 1GW0; 1GY1; 1GY2; 1GYC; 1KCW; 1OV8; 1QHQ; 1RCY; 1SDD; 1ZPU; 2CAK; 2CAL; 2H5U; 2IH8; 2IH9; 2J5W; 2Q9O; 2R7E; 3CDZ; 3DIV; 3DKH; 3FU7; 3FU8; 3FU9; 3GYR; 3J2Q; 3J2S; 3QPK; 4BDV; 4BXS; 4EJX; 4ENZ
» More

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