Entry: PS00079

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General information about the entry

Entry name [info] MULTICOPPER_OXIDASE1
Accession [info] PS00079
Entry type [info] PATTERN
Date [info] APR-1990 (CREATED); APR-2006 (DATA UPDATE); JUN-2014 (INFO UPDATE).
PROSITE Doc. [info] PDOC00076

Name and characterization of the entry

Description [info] Multicopper oxidases signature 1.
Pattern [info]
G-x-[FYW]-x-[LIVMFYW]-x-[CST]-x-{PR}-{K}-x(2)-{S}-x-{LFH}-G-[LM]-x(3)-
[LIVMFYW].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2014_07 which contains 546'000 sequence entries.


Total number of hits 199 in 149 different sequences
Number of true positive hits 159 in 109 different sequences
Number of 'unknown' hits
Number of false positive hits 40 in 40 different sequences
Number of false negative sequences 12
Number of 'partial' sequences 7
Precision (true positives / (true positives + false positives)) 79.90 %
Recall (true positives / (true positives + false negatives)) 92.98 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 3
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
109 sequences

ASO_CUCMA   (P24792), ASO_CUCPM   (P37064), ASO_CUCSA   (P14133), 
ASO_TOBAC   (Q40588), AURB_CHLAA  (P27197), CERU_HUMAN  (P00450), 
CERU_MOUSE  (Q61147), CERU_RAT    (P13635), CERU_SHEEP  (Q9XT27), 
COPA_PSESM  (P59571), COPA_PSEUB  (P12374), FA5V_OXYMI  (Q58L90), 
FA5V_OXYSU  (Q58L91), FA5V_PSETE  (Q7SZN0), FA5_BOVIN   (Q28107), 
FA5_HUMAN   (P12259), FA5_MOUSE   (O88783), FA5_PIG     (Q9GLP1), 
FA5_PSETE   (Q593B6), FA8_CANFA   (O18806), FA8_HUMAN   (P00451), 
FA8_MOUSE   (Q06194), FA8_PIG     (P12263), FET3_CANAX  (P78591), 
FET3_CANGA  (Q96WT3), FET3_KLULA  (Q6CII3), FET3_YEAST  (P38993), 
FET5_YEAST  (P43561), FIO1_SCHPO  (Q09920), GMC1_YEAST  (Q04399), 
HEPHL_ACRMI (B3EWZ9), HEPH_HUMAN  (Q9BQS7), HEPH_MOUSE  (Q9Z0Z4), 
HEPH_RAT    (Q920H8), HPHL1_HUMAN (Q6MZM0), HPHL1_MOUSE (Q3V1H3), 
LAC10_ARATH (Q6ID18), LAC10_ORYSJ (Q10ND7), LAC11_ARATH (Q8VZA1), 
LAC11_ORYSJ (Q0DHL5), LAC12_ARATH (Q9FLB5), LAC12_ORYSJ (Q0DHL2), 
LAC13_ARATH (Q9LYQ2), LAC14_ARATH (Q9FY79), LAC15_ARATH (Q84J37), 
LAC15_ORYSJ (Q339K6), LAC16_ARATH (Q1PDH6), LAC16_ORYSJ (Q7XE50), 
LAC17_ARATH (Q9FJD5), LAC17_ORYSJ (Q2RBK2), LAC18_ORYSI (A2XCN6), 
LAC18_ORYSJ (Q53LU4), LAC19_ORYSI (A2Y9C5), LAC19_ORYSJ (Q2R0L2), 
LAC1_AGABI  (Q12541), LAC1_ARATH  (Q9LMS3), LAC1_BOTFU  (Q12570), 
LAC1_CRYPA  (Q03966), LAC1_MELAO  (Q70KY3), LAC1_NEUCR  (P06811), 
LAC1_ORYSJ  (Q5ZCW1), LAC1_PHLRA  (Q01679), LAC1_PLEOS  (Q12729), 
LAC1_PYCCI  (O59896), LAC1_THACU  (P56193), LAC1_TRAHI  (Q02497), 
LAC1_TRAMX  (D0VWU3), LAC1_TRAVI  (Q99044), LAC20_ORYSI (A2Y9C2), 
LAC20_ORYSJ (Q2R0L0), LAC21_ORYSJ (Q2QZ80), LAC22_ORYSJ (Q0IQU1), 
LAC23_ORYSJ (Q2QYS3), LAC2_AGABI  (Q12542), LAC2_ARATH  (O81081), 
LAC2_BOTFU  (Q96WM9), LAC2_ORYSJ  (Q8RYM9), LAC2_PLEOS  (Q12739), 
LAC2_PODAS  (P78722), LAC2_THACU  (Q02075), LAC2_TRAVE  (Q12718), 
LAC2_TRAVI  (Q99046), LAC3_ARATH  (Q56YT0), LAC3_BOTFU  (Q96UM2), 
LAC3_ORYSJ  (Q941X2), LAC3_THACU  (Q02079), LAC3_TRAVI  (Q99049), 
LAC4_ARATH  (O80434), LAC4_ORYSJ  (Q5N9X2), LAC4_TRAVE  (Q12719), 
LAC4_TRAVI  (Q99055), LAC5_ARATH  (Q9SIY8), LAC5_ORYSJ  (Q5N9W4), 
LAC5_TRAVE  (Q12717), LAC5_TRAVI  (Q99056), LAC6_ARATH  (Q9ZPY2), 
LAC6_ORYSJ  (Q5N7A3), LAC7_ORYSJ  (Q5N7B4), LAC9_ORYSJ  (Q6Z8L2), 
MCO_STAAR   (Q6GIX3), MCO_STAAU   (Q69HT9), MCO_STAES   (Q8CQF6), 
MCO_STAHJ   (Q4LAB0), PCOA_ECOLX  (Q47452), PHSA_STRAT  (Q53692), 
RUS1_ACIFR  (P23742), RUS2_ACIFR  (P0C918), RUS_ACIF2   (B7JAQ0), 
SOXE_SULAC  (Q53765)
» More

UniProtKB/Swiss-Prot
False negative sequences
12 sequences

LAC14_ORYSJ (Q69L99), LAC1_EMENI  (P17489), LAC24_ORYSJ (Q2QUN2), 
LAC25_ORYSJ (Q0IP28), LAC4_THACU  (Q02081), LAC7_ARATH  (Q9SR40), 
LAC8_ARATH  (Q9LFD2), LAC8_ORYSJ  (Q0JHP8), LAC9_ARATH  (Q9LFD1), 
LACC_HALVD  (D4GPK6), LPR1_ARATH  (F4I4K5), LPR2_ARATH  (Q949X9)
» More

UniProtKB/Swiss-Prot
'Partial' sequences
7 sequences

LAC1B_CERUI (P85308), LAC1_GALSP  (P86351), LAC2D_CERUI (P85430), 
LAC2_CERUI  (P85149), LACC1_CERUI (P86328), LACC2_CERUI (P86327), 
MCOL1_ZINVI (P85414)
» More

UniProtKB/Swiss-Prot
False positive sequences
40 sequences

ACCD_CALFG  (Q7YIX5), AL15_ASPFU  (O60022), ATE_GRABC   (Q0BTF8), 
CALI_BOVIN  (Q28068), CALI_HUMAN  (Q13939), CALI_MOUSE  (Q8CDE2), 
CALI_RAT    (Q5XI58), DPO3A_STAEQ (Q5HNK2), DPO3A_STAES (Q8CNX0), 
DPOL1_SULOH (O50607), EXG1_YEAST  (P23776), EXG_SACU7   (Q876J3), 
FPOH_METAC  (Q8TQP1), GPR98_DANRE (Q6JAN0), HYAL4_HUMAN (Q2M3T9), 
HYAL_CONCN  (I0CME7), IMCL2_ORYSJ (Q5VNW5), MGLA_CLOTE  (Q896Y2), 
NDVA_RHOP2  (Q2J0F4), NDVA_RHOPS  (Q13BH6), NUD17_ARATH (Q9ZU95), 
PEPT_PASMU  (Q9CP05), PTTBC_BACSU (P39794), RIR1_TRYBB  (O15909), 
S15A4_BOVIN (A6QQL0), S15A4_HUMAN (Q8N697), S15A4_MOUSE (Q91W98), 
S15A4_RAT   (O09014), S15A4_XENLA (Q68F72), SIM2_MOUSE  (Q61079), 
THII_COXBU  (Q83CD9), UT1_CAPHI   (D3INW7), UT1_HUMAN   (Q13336), 
UT1_MOUSE   (Q8VHL0), UT1_RAT     (P97689), UT1_SHEEP   (C5MK33), 
UT2_HUMAN   (Q15849), UT2_MOUSE   (Q8R4T9), UT2_RAT     (Q62668), 
Y3934_DICDI (Q54B29)
» More

PDB
[Detailed view]
39 PDB

1A3Z; 1A8Z; 1AOZ; 1ASO; 1ASP; 1ASQ; 1CUR; 1GW0; 1GY1; 1GY2; 1GYC; 1KCW; 1OV8; 1QHQ; 1RCY; 1SDD; 1ZPU; 2CAK; 2CAL; 2H5U; 2IH8; 2IH9; 2J5W; 2Q9O; 2R7E; 3CDZ; 3DIV; 3DKH; 3FU7; 3FU8; 3FU9; 3GYR; 3J2Q; 3J2S; 3QPK; 4BDV; 4BXS; 4EJX; 4ENZ
» More

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