PROSITE entry PS00098
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Direct ScanProsite submission
General information about the entry
Entry name [info] | THIOLASE_1 |
Accession [info] | PS00098 |
Entry type [info] | PATTERN |
Date [info] |
01-APR-1990 CREATED;
01-APR-2006 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
PROSITE Doc. [info] | PDOC00092 |
Name and characterization of the entry
Description [info] | Thiolases acyl-enzyme intermediate signature. |
Pattern [info] |
[LIVM]-[NST]-{T}-x-C-[SAGLI]-[ST]-[SAG]-[LIVMFYNS]-x-[STAG]-[LIVM]-x(6)- [LIVM]. |
Numerical results [info]
Total number of hits | 277 in 277 different sequences |
Number of true positive hits | 263 in 263 different sequences |
Number of 'unknown' hits | 1 |
Number of false positive hits | 13 in 13 different sequences |
Number of false negative sequences | 48 |
Number of 'partial' sequences | 3 |
Precision (true positives / (true positives + false positives)) | 95.29 % |
Recall (true positives / (true positives + false negatives)) | 84.57 % |
Comments [info]
Taxonomic range [info] | Eukaryotes, Prokaryotes (Bacteria) |
Maximum number of repetitions [info] | 1 |
Site [info] | involved_formation_acyl-enzyme_intermediate at position 5 |
Version [info] | 2 |
Cross-references [info]
UniProtKB/Swiss-Prot True positive sequences |
263 sequences
ACCT2_ARATH (Q8S4Y1), ATOB_ECOLI (P76461), ATOB_HAEIN (P44873), ATOB_PSEAE (Q9I2A8), BKTB_CUPNH (Q0KBP1), CATF_ACIAD (Q43935), CLE1_ASPVE (A0A3T0ZHJ0), ECHB_BOVIN (O46629), ECHB_HUMAN (P55084), ECHB_MACFA (Q8HXX4), ECHB_MOUSE (Q99JY0), ECHB_PANTR (Q5R1W7), ECHB_RAT(Q60587), ECHH_CAEEL (P34255), ER10A_ASPFC (B0XMC1), ER10A_ASPFU (Q4WLA8), ER10A_GIBZE (I1RMA2), ER10B_ASPFC (B0YA65), ER10B_ASPFU (Q4WCL5), ER10B_GIBZE (I1RY81), ERG10_CANAL (A0A1D8PH52), ERG10_SACMO (P10551), ERG10_YEAST (P41338), FADA4_MYCBO (P66927), FADA4_MYCLE (P46707), FADA4_MYCS2 (A0R1Y7), FADA4_MYCTO (P9WG68), FADA4_MYCTU (P9WG69), FADA_ACIAD (Q6FF69), FADA_ACIB3 (B7H1I1), FADA_ACIB5 (B7I3P0), FADA_ACIBC (B2I2J8), FADA_ACIBS (B0VLX5), FADA_ACIBT (A3M1H9), FADA_ACIBY (B0VE46), FADA_AERHH (A0KEL0), FADA_AERS4 (A4STF3), FADA_ALCBS (Q0VNZ7), FADA_ALIF1 (Q5E8X7), FADA_ALIFM (B5FEW7), FADA_ALISL (B6EGU1), FADA_BACSU (O32177), FADA_CHRSD (Q1QUW9), FADA_CITK8 (A8ACZ3), FADA_COLP3 (Q489W4), FADA_CROS8 (A7MQM5), FADA_ECO24 (A7ZU50), FADA_ECO57 (Q8X8J4), FADA_ECOHS (A8A6V0), FADA_ECOK1 (A1AI32), FADA_ECOL5 (Q0TAL1), FADA_ECOL6 (Q8FBI3), FADA_ECOLI (P21151), FADA_ECOUT (Q1R467), FADA_ENT38 (A4WFX5), FADA_ENTCL (Q9F0Y6), FADA_ERWT9 (B2VFE0), FADA_ESCF3 (B7LTZ0), FADA_HAHCH (Q2SD23), FADA_IDILO (Q5QXH8), FADA_KLEP7 (A6TGM3), FADA_MARMS (A6VVM8), FADA_MARN8 (A1TZR8), FADA_PECAS (Q6DAP6), FADA_PECCP (C6DI66), FADA_PHOLL (Q7MZ91), FADA_PHOPR (Q6LW07), FADA_PSE14 (Q48GW4), FADA_PSEA6 (Q15ZF4), FADA_PSEA7 (A6V383), FADA_PSEAB (Q02PH7), FADA_PSEAE (Q9HZJ3), FADA_PSEE4 (Q1I7D5), FADA_PSEF5 (Q4KFC3), FADA_PSEFR (P28790), FADA_PSEMY (A4XSM9), FADA_PSEOL (Q93Q11), FADA_PSEP1 (A5W6G9), FADA_PSEPF (Q3K9D9), FADA_PSEPK (Q88L01), FADA_PSEPU (Q9R9W0), FADA_PSESM (Q87ZB3), FADA_PSET1 (Q3IJ24), FADA_PSEU2 (Q4ZRA1), FADA_PSYA2 (Q4FQC7), FADA_PSYCK (Q1Q8K0), FADA_PSYWF (A5WH98), FADA_SACD2 (Q21KB1), FADA_SALCH (Q57HM7), FADA_SALPA (Q5PKQ3), FADA_SALTI (P0A2H8), FADA_SALTY (P0A2H7), FADA_SERP5 (A8G8D0), FADA_SHEAM (A1S1I7), FADA_SHEB5 (A3CYJ3), FADA_SHEB8 (A6WH99), FADA_SHEDO (Q12TB5), FADA_SHEFN (Q08A40), FADA_SHELP (A3Q8U3), FADA_SHEON (Q8EKS0), FADA_SHEPC (A4Y1B5), FADA_SHESA (A0KR49), FADA_SHESM (Q0HPB8), FADA_SHESR (Q0I0T4), FADA_SHESW (A1RDW3), FADA_SHIBS (Q31UE3), FADA_SHIDS (Q32A20), FADA_SHIF8 (Q0SZ35), FADA_SHIFL (Q83PG2), FADA_SHISS (Q3YVC2), FADA_STUS1 (A4VKA4), FADA_VIBC3 (A5F464), FADA_VIBCH (Q9KNI0), FADA_VIBPA (Q87TP0), FADA_VIBVU (Q8DDK5), FADA_VIBVY (Q7MQI0), FADA_YERE8 (A1JIG3), FADA_YERP3 (A7FDF1), FADA_YERPA (Q1C2C3), FADA_YERPE (Q8ZAM9), FADA_YERPN (Q1CNA0), FADA_YERPP (A4TR28), FADA_YERPS (Q66FR9), FADI_AERHH (A0KK76), FADI_AERS4 (A4SMT9), FADI_CITK8 (A8ADP1), FADI_CROS8 (A7MH80), FADI_ECO24 (A7ZPF9), FADI_ECO27 (B7UFZ9), FADI_ECO45 (B7MGV8), FADI_ECO55 (B7LBJ6), FADI_ECO57 (Q8XCN9), FADI_ECO5E (B5YXY5), FADI_ECO7I (B7NP25), FADI_ECO81 (B7MY17), FADI_ECO8A (B7M6M3), FADI_ECOBW (C4ZVN3), FADI_ECODH (B1X9L5), FADI_ECOHS (A8A2L1), FADI_ECOK1 (A1ADI9), FADI_ECOL5 (Q0TFA5), FADI_ECOL6 (Q8FFG3), FADI_ECOLC (B1IXA4), FADI_ECOLI (P76503), FADI_ECOLU (B7N5V3), FADI_ECOSE (B6I6Q5), FADI_ECOSM (B1LME8), FADI_ECOUT (Q1R971), FADI_ENT38 (A4WCW7), FADI_ERWT9 (B2VJ10), FADI_ESCF3 (B7LLC9), FADI_KLEP3 (B5XVW1), FADI_KLEP7 (A6TC20), FADI_PECAS (Q6D2L6), FADI_PECCP (C6DAL8), FADI_PHOLL (Q7N287), FADI_PSET1 (Q3IEE3), FADI_SALA4 (B5EZS0), FADI_SALAR (A9MJ36), FADI_SALCH (Q57LW5), FADI_SALDC (B5FPN2), FADI_SALEP (B5R3S0), FADI_SALHS (B4TCA9), FADI_SALNS (B4SZR1), FADI_SALPA (Q5PCX7), FADI_SALPB (A9N452), FADI_SALPC (C0PZX5), FADI_SALPK (B5BBA0), FADI_SALSV (B4TQC3), FADI_SALTI (Q8Z4Y9), FADI_SALTY (Q8ZNA6), FADI_SERP5 (A8GH87), FADI_SHIB3 (B2TWV5), FADI_SHIBS (Q31YB6), FADI_SHIDS (Q32DJ3), FADI_SHIF8 (Q0T2E5), FADI_SHIFL (Q83K95), FADI_SHISS (Q3YZM1), FADI_YERE8 (A1JK23), FADI_YERP3 (A7FGK0), FADI_YERPA (Q1C659), FADI_YERPB (B2K8J6), FADI_YERPE (Q8ZD46), FADI_YERPG (A9R7W9), FADI_YERPN (Q1CHK1), FADI_YERPP (A4TM83), FADI_YERPS (Q668V0), FADI_YERPY (B1JGG1), KAT1_PETHY (C8YNG6), NLTP2_CAEEL (G5EDP2), PAAJ_ECOLI (P0C7L2), PAAJ_ECOLX (P0C7L3), PCAF_ACIAD (Q43974), PCAF_PSEAE (Q9I6R0), PCAF_PSEKB (Q8VPF1), PCAF_PSEPU (Q51956), PIGA_MONRU (A0A0S2CHA9), PKS11_TALMA (D7RJN5), PKSM_BACSU (P40872), PKSR_BACSU (O31784), SCP2_BOVIN (P07857), SCP2_CHICK (Q07598), SCP2_HUMAN (P22307), SCP2_MOUSE (P32020), SCP2_RABIT (O62742), SCP2_RAT(P11915), TAS1_CORMM (G3J9P0), THIA_CANTR (Q12598), THIB_CANTR (Q04677), THIK1_ARATH (Q8LF48), THIK2_ARATH (Q56WD9), THIK5_ARATH (Q570C8), THIKA_CANTR (P33290), THIKA_MOUSE (Q921H8), THIKA_RAT (P21775), THIKB_CANTR (P33291), THIKB_MOUSE (Q8VCH0), THIKB_RAT (P07871), THIK_ENCCU (Q8SVA6), THIK_HUMAN (P09110), THIK_YARLI (Q05493), THIK_YEAST (P27796), THIL1_DICDI (Q86AD9), THILA_XENLA (Q6NU46), THILB_XENLA (Q6GN02), THILH_CAEEL (Q22100), THIL_ALLVD (P45369), THIL_BOVIN (Q29RZ0), THIL_CHRVO (Q9ZHI1), THIL_CUPNH (P14611), THIL_DANRE (Q6AZA0), THIL_HUMAN (P24752), THIL_MACFA (Q8HXY6), THIL_MOUSE (Q8QZT1), THIL_PARDE (P54810), THIL_RAT(P17764), THIL_RHIME (P50174), THIL_SHIZO (P07097), THIL_THIVI (P45363), THIL_XENTR (Q5BKN8), THIL_YARLI (Q6L8K7), THIM_BOVIN (Q3T0R7), THIM_HUMAN (P42765), THIM_MOUSE (Q8BWT1), THIM_PONAB (Q5RES5), THIM_RAT(P13437), THLA_CLOAB (P45359), THLA_CLOD6 (Q18AR0), THLA_STAA3 (Q2FJQ9), THLA_STAA8 (Q2G124), THLA_STAAB (Q2YVF5), THLA_STAAC (Q5HIU0), THLA_STAAM (Q99WM3), THLA_STAAN (Q7A7L2), THLA_STAAR (Q6GJW4), THLA_STAAS (Q6GCB8), THLA_STAAW (Q8NY95), THLA_STAEQ (Q5HS07), THLA_STAES (Q8CQN7), THLA_SYNWW (Q0AVM3), THL_BACSU (P45855), Y0859_MYCTU (O53871), YQEF_ECOLI (Q46939)» more
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UniProtKB/Swiss-Prot False negative sequences |
48 sequences
AACT1_ARATH (Q9FIK7), FADA5_MYCTU (I6XHI4), FADA6_MYCTU (I6XHJ3), FADI_ALIF1 (Q5E3U0), FADI_ALIFM (B5FGB5), FADI_ALTMD (B4RTU9), FADI_COLP3 (Q47ZB6), FADI_IDILO (Q5QXN5), FADI_PHOPR (Q6LTK4), FADI_PSEA6 (Q15VA3), FADI_SHEAM (A1S7L7), FADI_SHEB2 (B8EE97), FADI_SHEB5 (A3D685), FADI_SHEB8 (A6WQ26), FADI_SHEB9 (A9KTW7), FADI_SHEDO (Q12P12), FADI_SHEFN (Q07ZP7), FADI_SHEHH (B0TL22), FADI_SHELP (A3QFP4), FADI_SHEON (Q8ECP6), FADI_SHEPA (A8H5T2), FADI_SHEPC (A4Y898), FADI_SHEPW (B8CPY7), FADI_SHESA (A0KV75), FADI_SHESH (A8FTR6), FADI_SHESM (Q0HKD2), FADI_SHESR (Q0HWN4), FADI_SHESW (A1RI91), FADI_SHEWM (B1KKT1), FADI_VIBC3 (A5F2P1), FADI_VIBCH (Q9KT59), FADI_VIBPA (Q87MM2), FADI_VIBVU (Q8DB48), FADI_VIBVY (Q7MIS4), THIC_HUMAN (Q9BWD1), THIC_MOUSE (Q8CAY6), THIC_RAT(Q5XI22), VRAB_STAA1 (Q9KWK4), VRAB_STAAC (Q5HIA0), VRAB_STAAM (Q7A2W9), VRAB_STAAN (Q7A768), VRAB_STAAR (Q6GJ93), VRAB_STAAS (Q6GBR1), VRAB_STAAW (Q7A1P9), VRAB_STAEQ (Q5HRH3), VRAB_STAES (Q8CTR0), VRAB_STAHJ (Q4L3Q1), YHFS_BACSU (O07618)» more |
UniProtKB/Swiss-Prot 'Partial' sequences |
3 sequences
THIL_PIG(P14610), THLA_CLODI (P45362), THLA_CLOPA (P81347) |
UniProtKB/Swiss-Prot 'Unknown' sequences |
1 sequence
PKS11_TALMQ (B6QK76) |
UniProtKB/Swiss-Prot False positive sequences |
13 sequences
C9B51_TRIFG (A0A517FNC6), DPASA_APISA (P9WEX0), DPMAA_METAN (P9WEX6), EPAA_ASPNC (A2QTE9), NODE_RHIME (P06230), NODE_RHIS3 (P72331), NOE4_RHIML (P06231), PKS1_SARSH (A5PHD6), POMT2_DANRE (F1Q8R9), SERB2_ARATH (Q9SHP0), SORB_HYPJQ (G0R6S9), STRU3_BPPAJ (P85503), SUBA_METRA (E9F5E7)» more |
PDB [Detailed view] |
102 PDB
1AFW; 1DLU; 1DLV; 1DM3; 1M1T; 1M4S; 1M4T; 1NL7; 1OU6; 1PXT; 1QFL; 1WDK; 1WDL; 1WDM; 2C7Y; 2C7Z; 2D3T; 2F2S; 2IB7; 2IB8; 2IB9; 2IBU; 2IBW; 2IBY; 2IIK; 2VU0; 2VU1; 2VU2; 2WKT; 2WKU; 2WKV; 2WL4; 2WL5; 2WL6; 2WU9; 3GOA; 4B3H; 4B3I; 4B3J; 4C2J; 4C2K; 4DD5; 4NZS; 4O99; 4W61; 4WYR; 4WYS; 4XL2; 5F0V; 5F38; 5LP7; 5XZ5; 5ZQZ; 5ZRV; 6AQP; 6ARE; 6ARF; 6ARG; 6ARL; 6ARR; 6ART; 6DV2; 6L2C; 6L2G; 7LBZ; 7LCA; 7LCL; 7LD2; 7LDC; 7LDT; 7LDU; 7LDV; 7LDW; 7O1I; 7O1L; 7O4Q; 7O4R; 7O4S; 7O4T; 7O4V; 8BNR; 8BNU; 8BRJ; 8GQH; 8GQJ; 8OPU; 8OPV; 8OPW; 8OPX; 8OPY; 8OQL; 8OQM; 8OQN; 8OQO; 8OQP; 8OQQ; 8OQR; 8OQS; 8OQT; 8OQU; 8OQV; 8PF8 » more |