Entry: PS00098

General information about the entry

Entry name [info] THIOLASE_1
Accession [info] PS00098
Entry type [info] PATTERN
Date [info] APR-1990 (CREATED); APR-2006 (DATA UPDATE); JUN-2015 (INFO UPDATE).
PROSITE Doc. [info] PDOC00092

Name and characterization of the entry

Description [info] Thiolases acyl-enzyme intermediate signature.
Pattern [info]
[LIVM]-[NST]-{T}-x-C-[SAGLI]-[ST]-[SAG]-[LIVMFYNS]-x-[STAG]-[LIVM]-x(6)-
[LIVM].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2015_08 which contains 320'201 sequence entries.


Total number of hits 254 in 254 different sequences
Number of true positive hits 250 in 250 different sequences
Number of 'unknown' hits 0
Number of false positive hits 4 in 4 different sequences
Number of false negative sequences 46
Number of 'partial' sequences 3
Precision (true positives / (true positives + false positives)) 98.43 %
Recall (true positives / (true positives + false negatives)) 84.46 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] involved_formation_acyl-enzyme_intermediate at position 5
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
250 sequences

ATOB_ECOLI  (P76461), ATOB_HAEIN  (P44873), ATOB_PSEAE  (Q9I2A8), 
BKTB_CUPNH  (Q0KBP1), CATF_ACIAD  (Q43935), ECHB_BOVIN  (O46629), 
ECHB_HUMAN  (P55084), ECHB_MACFA  (Q8HXX4), ECHB_MOUSE  (Q99JY0), 
ECHB_PANTR  (Q5R1W7), ECHB_RAT    (Q60587), FADA4_MYCBO (P66927), 
FADA4_MYCLE (P46707), FADA4_MYCS2 (A0R1Y7), FADA4_MYCTO (P9WG68), 
FADA4_MYCTU (P9WG69), FADA_ACIAD  (Q6FF69), FADA_ACIB3  (B7H1I1), 
FADA_ACIB5  (B7I3P0), FADA_ACIBC  (B2I2J8), FADA_ACIBS  (B0VLX5), 
FADA_ACIBT  (A3M1H9), FADA_ACIBY  (B0VE46), FADA_AERHH  (A0KEL0), 
FADA_AERS4  (A4STF3), FADA_ALCBS  (Q0VNZ7), FADA_ALISL  (B6EGU1), 
FADA_BACSU  (O32177), FADA_CHRSD  (Q1QUW9), FADA_CITK8  (A8ACZ3), 
FADA_COLP3  (Q489W4), FADA_CROS8  (A7MQM5), FADA_ECO24  (A7ZU50), 
FADA_ECO57  (Q8X8J4), FADA_ECOHS  (A8A6V0), FADA_ECOK1  (A1AI32), 
FADA_ECOL5  (Q0TAL1), FADA_ECOL6  (Q8FBI3), FADA_ECOLI  (P21151), 
FADA_ECOUT  (Q1R467), FADA_ENT38  (A4WFX5), FADA_ENTCL  (Q9F0Y6), 
FADA_ERWT9  (B2VFE0), FADA_ESCF3  (B7LTZ0), FADA_HAHCH  (Q2SD23), 
FADA_IDILO  (Q5QXH8), FADA_KLEP7  (A6TGM3), FADA_MARHV  (A1TZR8), 
FADA_MARMS  (A6VVM8), FADA_PECAS  (Q6DAP6), FADA_PECCP  (C6DI66), 
FADA_PHOLL  (Q7MZ91), FADA_PHOPR  (Q6LW07), FADA_PSE14  (Q48GW4), 
FADA_PSEA6  (Q15ZF4), FADA_PSEA7  (A6V383), FADA_PSEAB  (Q02PH7), 
FADA_PSEAE  (Q9HZJ3), FADA_PSEE4  (Q1I7D5), FADA_PSEF5  (Q4KFC3), 
FADA_PSEFR  (P28790), FADA_PSEHT  (Q3IJ24), FADA_PSEMY  (A4XSM9), 
FADA_PSEOL  (Q93Q11), FADA_PSEP1  (A5W6G9), FADA_PSEPF  (Q3K9D9), 
FADA_PSEPK  (Q88L01), FADA_PSEPU  (Q9R9W0), FADA_PSESM  (Q87ZB3), 
FADA_PSEU2  (Q4ZRA1), FADA_PSEU5  (A4VKA4), FADA_PSYA2  (Q4FQC7), 
FADA_PSYCK  (Q1Q8K0), FADA_PSYWF  (A5WH98), FADA_SACD2  (Q21KB1), 
FADA_SALCH  (Q57HM7), FADA_SALPA  (Q5PKQ3), FADA_SALTI  (P0A2H8), 
FADA_SALTY  (P0A2H7), FADA_SERP5  (A8G8D0), FADA_SHEAM  (A1S1I7), 
FADA_SHEB5  (A3CYJ3), FADA_SHEB8  (A6WH99), FADA_SHEDO  (Q12TB5), 
FADA_SHEFN  (Q08A40), FADA_SHELP  (A3Q8U3), FADA_SHEON  (Q8EKS0), 
FADA_SHEPC  (A4Y1B5), FADA_SHESA  (A0KR49), FADA_SHESM  (Q0HPB8), 
FADA_SHESR  (Q0I0T4), FADA_SHESW  (A1RDW3), FADA_SHIBS  (Q31UE3), 
FADA_SHIDS  (Q32A20), FADA_SHIF8  (Q0SZ35), FADA_SHIFL  (Q83PG2), 
FADA_SHISS  (Q3YVC2), FADA_VIBC3  (A5F464), FADA_VIBCH  (Q9KNI0), 
FADA_VIBF1  (Q5E8X7), FADA_VIBFM  (B5FEW7), FADA_VIBPA  (Q87TP0), 
FADA_VIBVU  (Q8DDK5), FADA_VIBVY  (Q7MQI0), FADA_YERE8  (A1JIG3), 
FADA_YERP3  (A7FDF1), FADA_YERPA  (Q1C2C3), FADA_YERPE  (Q8ZAM9), 
FADA_YERPN  (Q1CNA0), FADA_YERPP  (A4TR28), FADA_YERPS  (Q66FR9), 
FADI_AERHH  (A0KK76), FADI_AERS4  (A4SMT9), FADI_CITK8  (A8ADP1), 
FADI_CROS8  (A7MH80), FADI_ECO24  (A7ZPF9), FADI_ECO27  (B7UFZ9), 
FADI_ECO45  (B7MGV8), FADI_ECO55  (B7LBJ6), FADI_ECO57  (Q8XCN9), 
FADI_ECO5E  (B5YXY5), FADI_ECO7I  (B7NP25), FADI_ECO81  (B7MY17), 
FADI_ECO8A  (B7M6M3), FADI_ECOBW  (C4ZVN3), FADI_ECODH  (B1X9L5), 
FADI_ECOHS  (A8A2L1), FADI_ECOK1  (A1ADI9), FADI_ECOL5  (Q0TFA5), 
FADI_ECOL6  (Q8FFG3), FADI_ECOLC  (B1IXA4), FADI_ECOLI  (P76503), 
FADI_ECOLU  (B7N5V3), FADI_ECOSE  (B6I6Q5), FADI_ECOSM  (B1LME8), 
FADI_ECOUT  (Q1R971), FADI_ENT38  (A4WCW7), FADI_ERWT9  (B2VJ10), 
FADI_ESCF3  (B7LLC9), FADI_KLEP3  (B5XVW1), FADI_KLEP7  (A6TC20), 
FADI_PECAS  (Q6D2L6), FADI_PECCP  (C6DAL8), FADI_PHOLL  (Q7N287), 
FADI_PSEHT  (Q3IEE3), FADI_SALA4  (B5EZS0), FADI_SALAR  (A9MJ36), 
FADI_SALCH  (Q57LW5), FADI_SALDC  (B5FPN2), FADI_SALEP  (B5R3S0), 
FADI_SALHS  (B4TCA9), FADI_SALNS  (B4SZR1), FADI_SALPA  (Q5PCX7), 
FADI_SALPB  (A9N452), FADI_SALPC  (C0PZX5), FADI_SALPK  (B5BBA0), 
FADI_SALSV  (B4TQC3), FADI_SALTI  (Q8Z4Y9), FADI_SALTY  (Q8ZNA6), 
FADI_SERP5  (A8GH87), FADI_SHIB3  (B2TWV5), FADI_SHIBS  (Q31YB6), 
FADI_SHIDS  (Q32DJ3), FADI_SHIF8  (Q0T2E5), FADI_SHIFL  (Q83K95), 
FADI_SHISS  (Q3YZM1), FADI_YERE8  (A1JK23), FADI_YERP3  (A7FGK0), 
FADI_YERPA  (Q1C659), FADI_YERPB  (B2K8J6), FADI_YERPE  (Q8ZD46), 
FADI_YERPG  (A9R7W9), FADI_YERPN  (Q1CHK1), FADI_YERPP  (A4TM83), 
FADI_YERPS  (Q668V0), FADI_YERPY  (B1JGG1), NLTP2_CAEEL (G5EDP2), 
NLTP_BOVIN  (P07857), NLTP_CHICK  (Q07598), NLTP_HUMAN  (P22307), 
NLTP_MOUSE  (P32020), NLTP_RABIT  (O62742), NLTP_RAT    (P11915), 
PAAJ_ECOLI  (P0C7L2), PAAJ_ECOLX  (P0C7L3), PCAF_ACIAD  (Q43974), 
PCAF_PSEAE  (Q9I6R0), PCAF_PSEKB  (Q8VPF1), PCAF_PSEPU  (Q51956), 
PKSM_BACSU  (P40872), PKSR_BACSU  (O31784), THIA_CANTR  (Q12598), 
THIB_CANTR  (Q04677), THIC1_ARATH (Q8S4Y1), THIK1_ARATH (Q8LF48), 
THIK2_ARATH (Q56WD9), THIK5_ARATH (Q570C8), THIKA_CANTR (P33290), 
THIKA_MOUSE (Q921H8), THIKA_RAT   (P21775), THIKB_CANTR (P33291), 
THIKB_MOUSE (Q8VCH0), THIKB_RAT   (P07871), THIK_ENCCU  (Q8SVA6), 
THIK_HUMAN  (P09110), THIK_YARLI  (Q05493), THIK_YEAST  (P27796), 
THIL1_DICDI (Q86AD9), THILA_XENLA (Q6NU46), THILB_XENLA (Q6GN02), 
THILH_CAEEL (Q22100), THIL_ALLVD  (P45369), THIL_BOVIN  (Q29RZ0), 
THIL_CHRVO  (Q9ZHI1), THIL_CUPNH  (P14611), THIL_DANRE  (Q6AZA0), 
THIL_HUMAN  (P24752), THIL_MACFA  (Q8HXY6), THIL_MOUSE  (Q8QZT1), 
THIL_PARDE  (P54810), THIL_RAT    (P17764), THIL_RHIME  (P50174), 
THIL_SACMO  (P10551), THIL_THIVI  (P45363), THIL_XENTR  (Q5BKN8), 
THIL_YARLI  (Q6L8K7), THIL_YEAST  (P41338), THIL_ZOORA  (P07097), 
THIM_BOVIN  (Q3T0R7), THIM_HUMAN  (P42765), THIM_MOUSE  (Q8BWT1), 
THIM_PONAB  (Q5RES5), THIM_RAT    (P13437), THLA_CLOAB  (P45359), 
THLA_PEPD6  (Q18AR0), THLA_STAA3  (Q2FJQ9), THLA_STAA8  (Q2G124), 
THLA_STAAB  (Q2YVF5), THLA_STAAC  (Q5HIU0), THLA_STAAM  (Q99WM3), 
THLA_STAAN  (Q7A7L2), THLA_STAAR  (Q6GJW4), THLA_STAAS  (Q6GCB8), 
THLA_STAAW  (Q8NY95), THLA_STAEQ  (Q5HS07), THLA_STAES  (Q8CQN7), 
THL_BACSU   (P45855), Y0859_MYCTU (O53871), YKA3_CAEEL  (P34255), 
YQEF_ECOLI  (Q46939)
» More

UniProtKB/Swiss-Prot
False negative sequences
46 sequences

FADI_ALTMD  (B4RTU9), FADI_COLP3  (Q47ZB6), FADI_IDILO  (Q5QXN5), 
FADI_PHOPR  (Q6LTK4), FADI_PSEA6  (Q15VA3), FADI_SHEAM  (A1S7L7), 
FADI_SHEB2  (B8EE97), FADI_SHEB5  (A3D685), FADI_SHEB8  (A6WQ26), 
FADI_SHEB9  (A9KTW7), FADI_SHEDO  (Q12P12), FADI_SHEFN  (Q07ZP7), 
FADI_SHEHH  (B0TL22), FADI_SHELP  (A3QFP4), FADI_SHEON  (Q8ECP6), 
FADI_SHEPA  (A8H5T2), FADI_SHEPC  (A4Y898), FADI_SHEPW  (B8CPY7), 
FADI_SHESA  (A0KV75), FADI_SHESH  (A8FTR6), FADI_SHESM  (Q0HKD2), 
FADI_SHESR  (Q0HWN4), FADI_SHESW  (A1RI91), FADI_SHEWM  (B1KKT1), 
FADI_VIBC3  (A5F2P1), FADI_VIBCH  (Q9KT59), FADI_VIBF1  (Q5E3U0), 
FADI_VIBFM  (B5FGB5), FADI_VIBPA  (Q87MM2), FADI_VIBVU  (Q8DB48), 
FADI_VIBVY  (Q7MIS4), THIC2_ARATH (Q9FIK7), THIC_HUMAN  (Q9BWD1), 
THIC_MOUSE  (Q8CAY6), THIC_RAT    (Q5XI22), VRAB_STAA1  (Q9KWK4), 
VRAB_STAAC  (Q5HIA0), VRAB_STAAM  (Q7A2W9), VRAB_STAAN  (Q7A768), 
VRAB_STAAR  (Q6GJ93), VRAB_STAAS  (Q6GBR1), VRAB_STAAW  (Q7A1P9), 
VRAB_STAEQ  (Q5HRH3), VRAB_STAES  (Q8CTR0), VRAB_STAHJ  (Q4L3Q1), 
YHFS_BACSU  (O07618)
» More

UniProtKB/Swiss-Prot
'Partial' sequences
3 sequences

THIL_PIG    (P14610), THL_CLOPA   (P81347), THL_PEPDI   (P45362)

		
UniProtKB/Swiss-Prot
False positive sequences
4 sequences

NODE_RHIME  (P06230), NODE_RHIS3  (P72331), NOE4_RHIML  (P06231), 
STRU3_BPPAJ (P85503)
» More

PDB
[Detailed view]
30 PDB

1AFW; 1DLU; 1DLV; 1M1T; 1PXT; 1WDK; 1WDL; 1WDM; 2C7Y; 2C7Z; 2D3T; 2IB7; 2IB8; 2IB9; 2IIK; 2VU2; 2WKT; 2WKU; 2WKV; 2WL4; 2WL5; 2WL6; 2WU9; 4B3H; 4B3I; 4B3J; 4C2K; 4DD5; 4NZS; 4O99
» More

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View entry in raw text format (no links)
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