Entry: PS00098

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General information about the entry

Entry name [info] THIOLASE_1
Accession [info] PS00098
Entry type [info] PATTERN
Date [info] APR-1990 (CREATED); APR-2006 (DATA UPDATE); JUL-2014 (INFO UPDATE).
PROSITE Doc. [info] PDOC00092

Name and characterization of the entry

Description [info] Thiolases acyl-enzyme intermediate signature.
Pattern [info]
[LIVM]-[NST]-{T}-x-C-[SAGLI]-[ST]-[SAG]-[LIVMFYNS]-x-[STAG]-[LIVM]-x(6)-
[LIVM].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2014_09 which contains 546'439 sequence entries.


Total number of hits 252 in 252 different sequences
Number of true positive hits 248 in 248 different sequences
Number of 'unknown' hits
Number of false positive hits 4 in 4 different sequences
Number of false negative sequences 46
Number of 'partial' sequences 3
Precision (true positives / (true positives + false positives)) 98.41 %
Recall (true positives / (true positives + false negatives)) 84.35 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] involved_formation_acyl-enzyme_intermediate at position 5
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
248 sequences

ATOB_ECOLI  (P76461), ATOB_HAEIN  (P44873), ATOB_PSEAE  (Q9I2A8), 
BKTB_CUPNH  (Q0KBP1), CATF_ACIAD  (Q43935), ECHB_BOVIN  (O46629), 
ECHB_HUMAN  (P55084), ECHB_MACFA  (Q8HXX4), ECHB_MOUSE  (Q99JY0), 
ECHB_PANTR  (Q5R1W7), ECHB_RAT    (Q60587), FADA4_MYCBO (P66927), 
FADA4_MYCLE (P46707), FADA4_MYCS2 (A0R1Y7), FADA4_MYCTO (P9WG68), 
FADA4_MYCTU (P9WG69), FADA_ACIAD  (Q6FF69), FADA_ACIB3  (B7H1I1), 
FADA_ACIB5  (B7I3P0), FADA_ACIBC  (B2I2J8), FADA_ACIBS  (B0VLX5), 
FADA_ACIBT  (A3M1H9), FADA_ACIBY  (B0VE46), FADA_AERHH  (A0KEL0), 
FADA_AERS4  (A4STF3), FADA_ALCBS  (Q0VNZ7), FADA_ALISL  (B6EGU1), 
FADA_BACSU  (O32177), FADA_CHRSD  (Q1QUW9), FADA_CITK8  (A8ACZ3), 
FADA_COLP3  (Q489W4), FADA_CROS8  (A7MQM5), FADA_ECO24  (A7ZU50), 
FADA_ECO57  (Q8X8J4), FADA_ECOHS  (A8A6V0), FADA_ECOK1  (A1AI32), 
FADA_ECOL5  (Q0TAL1), FADA_ECOL6  (Q8FBI3), FADA_ECOLI  (P21151), 
FADA_ECOUT  (Q1R467), FADA_ENT38  (A4WFX5), FADA_ENTCL  (Q9F0Y6), 
FADA_ERWT9  (B2VFE0), FADA_ESCF3  (B7LTZ0), FADA_HAHCH  (Q2SD23), 
FADA_IDILO  (Q5QXH8), FADA_KLEP7  (A6TGM3), FADA_MARAV  (A1TZR8), 
FADA_MARMS  (A6VVM8), FADA_PECAS  (Q6DAP6), FADA_PECCP  (C6DI66), 
FADA_PHOLL  (Q7MZ91), FADA_PHOPR  (Q6LW07), FADA_PSE14  (Q48GW4), 
FADA_PSEA6  (Q15ZF4), FADA_PSEA7  (A6V383), FADA_PSEAB  (Q02PH7), 
FADA_PSEAE  (Q9HZJ3), FADA_PSEE4  (Q1I7D5), FADA_PSEF5  (Q4KFC3), 
FADA_PSEFR  (P28790), FADA_PSEHT  (Q3IJ24), FADA_PSEMY  (A4XSM9), 
FADA_PSEOL  (Q93Q11), FADA_PSEP1  (A5W6G9), FADA_PSEPF  (Q3K9D9), 
FADA_PSEPK  (Q88L01), FADA_PSEPU  (Q9R9W0), FADA_PSESM  (Q87ZB3), 
FADA_PSEU2  (Q4ZRA1), FADA_PSEU5  (A4VKA4), FADA_PSYA2  (Q4FQC7), 
FADA_PSYCK  (Q1Q8K0), FADA_PSYWF  (A5WH98), FADA_SACD2  (Q21KB1), 
FADA_SALCH  (Q57HM7), FADA_SALPA  (Q5PKQ3), FADA_SALTI  (P0A2H8), 
FADA_SALTY  (P0A2H7), FADA_SERP5  (A8G8D0), FADA_SHEAM  (A1S1I7), 
FADA_SHEB5  (A3CYJ3), FADA_SHEB8  (A6WH99), FADA_SHEDO  (Q12TB5), 
FADA_SHEFN  (Q08A40), FADA_SHELP  (A3Q8U3), FADA_SHEON  (Q8EKS0), 
FADA_SHEPC  (A4Y1B5), FADA_SHESA  (A0KR49), FADA_SHESM  (Q0HPB8), 
FADA_SHESR  (Q0I0T4), FADA_SHESW  (A1RDW3), FADA_SHIBS  (Q31UE3), 
FADA_SHIDS  (Q32A20), FADA_SHIF8  (Q0SZ35), FADA_SHIFL  (Q83PG2), 
FADA_SHISS  (Q3YVC2), FADA_VIBC3  (A5F464), FADA_VIBCH  (Q9KNI0), 
FADA_VIBF1  (Q5E8X7), FADA_VIBFM  (B5FEW7), FADA_VIBPA  (Q87TP0), 
FADA_VIBVU  (Q8DDK5), FADA_VIBVY  (Q7MQI0), FADA_YERE8  (A1JIG3), 
FADA_YERP3  (A7FDF1), FADA_YERPA  (Q1C2C3), FADA_YERPE  (Q8ZAM9), 
FADA_YERPN  (Q1CNA0), FADA_YERPP  (A4TR28), FADA_YERPS  (Q66FR9), 
FADI_AERHH  (A0KK76), FADI_AERS4  (A4SMT9), FADI_CITK8  (A8ADP1), 
FADI_CROS8  (A7MH80), FADI_ECO24  (A7ZPF9), FADI_ECO27  (B7UFZ9), 
FADI_ECO45  (B7MGV8), FADI_ECO55  (B7LBJ6), FADI_ECO57  (Q8XCN9), 
FADI_ECO5E  (B5YXY5), FADI_ECO7I  (B7NP25), FADI_ECO81  (B7MY17), 
FADI_ECO8A  (B7M6M3), FADI_ECOBW  (C4ZVN3), FADI_ECODH  (B1X9L5), 
FADI_ECOHS  (A8A2L1), FADI_ECOK1  (A1ADI9), FADI_ECOL5  (Q0TFA5), 
FADI_ECOL6  (Q8FFG3), FADI_ECOLC  (B1IXA4), FADI_ECOLI  (P76503), 
FADI_ECOLU  (B7N5V3), FADI_ECOSE  (B6I6Q5), FADI_ECOSM  (B1LME8), 
FADI_ECOUT  (Q1R971), FADI_ENT38  (A4WCW7), FADI_ERWT9  (B2VJ10), 
FADI_ESCF3  (B7LLC9), FADI_KLEP3  (B5XVW1), FADI_KLEP7  (A6TC20), 
FADI_PECAS  (Q6D2L6), FADI_PECCP  (C6DAL8), FADI_PHOLL  (Q7N287), 
FADI_PSEHT  (Q3IEE3), FADI_SALA4  (B5EZS0), FADI_SALAR  (A9MJ36), 
FADI_SALCH  (Q57LW5), FADI_SALDC  (B5FPN2), FADI_SALEP  (B5R3S0), 
FADI_SALHS  (B4TCA9), FADI_SALNS  (B4SZR1), FADI_SALPA  (Q5PCX7), 
FADI_SALPB  (A9N452), FADI_SALPC  (C0PZX5), FADI_SALPK  (B5BBA0), 
FADI_SALSV  (B4TQC3), FADI_SALTI  (Q8Z4Y9), FADI_SALTY  (Q8ZNA6), 
FADI_SERP5  (A8GH87), FADI_SHIB3  (B2TWV5), FADI_SHIBS  (Q31YB6), 
FADI_SHIDS  (Q32DJ3), FADI_SHIF8  (Q0T2E5), FADI_SHIFL  (Q83K95), 
FADI_SHISS  (Q3YZM1), FADI_YERE8  (A1JK23), FADI_YERP3  (A7FGK0), 
FADI_YERPA  (Q1C659), FADI_YERPB  (B2K8J6), FADI_YERPE  (Q8ZD46), 
FADI_YERPG  (A9R7W9), FADI_YERPN  (Q1CHK1), FADI_YERPP  (A4TM83), 
FADI_YERPS  (Q668V0), FADI_YERPY  (B1JGG1), NLTP_BOVIN  (P07857), 
NLTP_CHICK  (Q07598), NLTP_HUMAN  (P22307), NLTP_MOUSE  (P32020), 
NLTP_RABIT  (O62742), NLTP_RAT    (P11915), PAAJ_ECOLI  (P0C7L2), 
PAAJ_ECOLX  (P0C7L3), PCAF_ACIAD  (Q43974), PCAF_PSEAE  (Q9I6R0), 
PCAF_PSEPU  (Q51956), PCAF_PSESB  (Q8VPF1), PKSM_BACSU  (P40872), 
PKSR_BACSU  (O31784), THIA_CANTR  (Q12598), THIB_CANTR  (Q04677), 
THIC1_ARATH (Q8S4Y1), THIK1_ARATH (Q8LF48), THIK2_ARATH (Q56WD9), 
THIK5_ARATH (Q570C8), THIKA_CANTR (P33290), THIKA_MOUSE (Q921H8), 
THIKA_RAT   (P21775), THIKB_CANTR (P33291), THIKB_MOUSE (Q8VCH0), 
THIKB_RAT   (P07871), THIK_ENCCU  (Q8SVA6), THIK_HUMAN  (P09110), 
THIK_YARLI  (Q05493), THIK_YEAST  (P27796), THIL1_DICDI (Q86AD9), 
THILA_XENLA (Q6NU46), THILB_XENLA (Q6GN02), THIL_ALLVD  (P45369), 
THIL_BOVIN  (Q29RZ0), THIL_CHRVO  (Q9ZHI1), THIL_CUPNH  (P14611), 
THIL_DANRE  (Q6AZA0), THIL_HUMAN  (P24752), THIL_MACFA  (Q8HXY6), 
THIL_MOUSE  (Q8QZT1), THIL_PARDE  (P54810), THIL_RAT    (P17764), 
THIL_RHIME  (P50174), THIL_SACMO  (P10551), THIL_THIVI  (P45363), 
THIL_XENTR  (Q5BKN8), THIL_YARLI  (Q6L8K7), THIL_YEAST  (P41338), 
THIL_ZOORA  (P07097), THIM_BOVIN  (Q3T0R7), THIM_HUMAN  (P42765), 
THIM_MOUSE  (Q8BWT1), THIM_PONAB  (Q5RES5), THIM_RAT    (P13437), 
THLA_CLOAB  (P45359), THLA_PEPD6  (Q18AR0), THLA_STAA3  (Q2FJQ9), 
THLA_STAA8  (Q2G124), THLA_STAAB  (Q2YVF5), THLA_STAAC  (Q5HIU0), 
THLA_STAAM  (Q99WM3), THLA_STAAN  (Q7A7L2), THLA_STAAR  (Q6GJW4), 
THLA_STAAS  (Q6GCB8), THLA_STAAW  (Q8NY95), THLA_STAEQ  (Q5HS07), 
THLA_STAES  (Q8CQN7), THL_BACSU   (P45855), Y0859_MYCTU (O53871), 
YKA3_CAEEL  (P34255), YQEF_ECOLI  (Q46939)
» More

UniProtKB/Swiss-Prot
False negative sequences
46 sequences

FADI_ALTMD  (B4RTU9), FADI_COLP3  (Q47ZB6), FADI_IDILO  (Q5QXN5), 
FADI_PHOPR  (Q6LTK4), FADI_PSEA6  (Q15VA3), FADI_SHEAM  (A1S7L7), 
FADI_SHEB2  (B8EE97), FADI_SHEB5  (A3D685), FADI_SHEB8  (A6WQ26), 
FADI_SHEB9  (A9KTW7), FADI_SHEDO  (Q12P12), FADI_SHEFN  (Q07ZP7), 
FADI_SHEHH  (B0TL22), FADI_SHELP  (A3QFP4), FADI_SHEON  (Q8ECP6), 
FADI_SHEPA  (A8H5T2), FADI_SHEPC  (A4Y898), FADI_SHEPW  (B8CPY7), 
FADI_SHESA  (A0KV75), FADI_SHESH  (A8FTR6), FADI_SHESM  (Q0HKD2), 
FADI_SHESR  (Q0HWN4), FADI_SHESW  (A1RI91), FADI_SHEWM  (B1KKT1), 
FADI_VIBC3  (A5F2P1), FADI_VIBCH  (Q9KT59), FADI_VIBF1  (Q5E3U0), 
FADI_VIBFM  (B5FGB5), FADI_VIBPA  (Q87MM2), FADI_VIBVU  (Q8DB48), 
FADI_VIBVY  (Q7MIS4), THIC2_ARATH (Q9FIK7), THIC_HUMAN  (Q9BWD1), 
THIC_MOUSE  (Q8CAY6), THIC_RAT    (Q5XI22), VRAB_STAA1  (Q9KWK4), 
VRAB_STAAC  (Q5HIA0), VRAB_STAAM  (Q7A2W9), VRAB_STAAN  (Q7A768), 
VRAB_STAAR  (Q6GJ93), VRAB_STAAS  (Q6GBR1), VRAB_STAAW  (Q7A1P9), 
VRAB_STAEQ  (Q5HRH3), VRAB_STAES  (Q8CTR0), VRAB_STAHJ  (Q4L3Q1), 
YHFS_BACSU  (O07618)
» More

UniProtKB/Swiss-Prot
'Partial' sequences
3 sequences

THIL_PIG    (P14610), THL_CLOPA   (P81347), THL_PEPDI   (P45362)

		
UniProtKB/Swiss-Prot
False positive sequences
4 sequences

NODE_RHIME  (P06230), NODE_RHIS3  (P72331), NOE4_RHIML  (P06231), 
STRU3_BPPAJ (P85503)
» More

PDB
[Detailed view]
27 PDB

1AFW; 1DLU; 1DLV; 1M1T; 1PXT; 1WDK; 1WDL; 1WDM; 2C7Y; 2C7Z; 2D3T; 2IB7; 2IB8; 2IB9; 2IIK; 2VU2; 2WKT; 2WKU; 2WKV; 2WL4; 2WL5; 2WL6; 2WU9; 4B3H; 4B3I; 4B3J; 4DD5
» More

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View entry in raw text format (no links)
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