To improve security and privacy, we are moving our web pages and services from HTTP to HTTPS.
To give users of web services time to transition to HTTPS, we will support separate HTTP and HTTPS services until the end of 2017.
From January 2018 most HTTP traffic will be automatically redirected to HTTPS. [more...]
View this page in https
Entry: PS00098

General information about the entry

Entry name [info] THIOLASE_1
Accession [info] PS00098
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED; 01-APR-2006 DATA UPDATE; 27-SEP-2017 INFO UPDATE.
PROSITE Doc. [info] PDOC00092

Name and characterization of the entry

Description [info] Thiolases acyl-enzyme intermediate signature.
Pattern [info]
[LIVM]-[NST]-{T}-x-C-[SAGLI]-[ST]-[SAG]-[LIVMFYNS]-x-[STAG]-[LIVM]-x(6)-
[LIVM].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2017_09 which contains 555'594 sequence entries.


Total number of hits 254 in 254 different sequences
Number of true positive hits 250 in 250 different sequences
Number of 'unknown' hits 0
Number of false positive hits 4 in 4 different sequences
Number of false negative sequences 47
Number of 'partial' sequences 3
Precision (true positives / (true positives + false positives)) 98.43 %
Recall (true positives / (true positives + false negatives)) 84.18 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] involved_formation_acyl-enzyme_intermediate at position 5
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
250 sequences

ATOB_ECOLI  (P76461    ), ATOB_HAEIN  (P44873    ), ATOB_PSEAE  (Q9I2A8    ), 
BKTB_CUPNH  (Q0KBP1    ), CATF_ACIAD  (Q43935    ), ECHB_BOVIN  (O46629    ), 
ECHB_HUMAN  (P55084    ), ECHB_MACFA  (Q8HXX4    ), ECHB_MOUSE  (Q99JY0    ), 
ECHB_PANTR  (Q5R1W7    ), ECHB_RAT    (Q60587    ), FADA4_MYCBO (P66927    ), 
FADA4_MYCLE (P46707    ), FADA4_MYCS2 (A0R1Y7    ), FADA4_MYCTO (P9WG68    ), 
FADA4_MYCTU (P9WG69    ), FADA_ACIAD  (Q6FF69    ), FADA_ACIB3  (B7H1I1    ), 
FADA_ACIB5  (B7I3P0    ), FADA_ACIBC  (B2I2J8    ), FADA_ACIBS  (B0VLX5    ), 
FADA_ACIBT  (A3M1H9    ), FADA_ACIBY  (B0VE46    ), FADA_AERHH  (A0KEL0    ), 
FADA_AERS4  (A4STF3    ), FADA_ALCBS  (Q0VNZ7    ), FADA_ALISL  (B6EGU1    ), 
FADA_BACSU  (O32177    ), FADA_CHRSD  (Q1QUW9    ), FADA_CITK8  (A8ACZ3    ), 
FADA_COLP3  (Q489W4    ), FADA_CROS8  (A7MQM5    ), FADA_ECO24  (A7ZU50    ), 
FADA_ECO57  (Q8X8J4    ), FADA_ECOHS  (A8A6V0    ), FADA_ECOK1  (A1AI32    ), 
FADA_ECOL5  (Q0TAL1    ), FADA_ECOL6  (Q8FBI3    ), FADA_ECOLI  (P21151    ), 
FADA_ECOUT  (Q1R467    ), FADA_ENT38  (A4WFX5    ), FADA_ENTCL  (Q9F0Y6    ), 
FADA_ERWT9  (B2VFE0    ), FADA_ESCF3  (B7LTZ0    ), FADA_HAHCH  (Q2SD23    ), 
FADA_IDILO  (Q5QXH8    ), FADA_KLEP7  (A6TGM3    ), FADA_MARHV  (A1TZR8    ), 
FADA_MARMS  (A6VVM8    ), FADA_PECAS  (Q6DAP6    ), FADA_PECCP  (C6DI66    ), 
FADA_PHOLL  (Q7MZ91    ), FADA_PHOPR  (Q6LW07    ), FADA_PSE14  (Q48GW4    ), 
FADA_PSEA6  (Q15ZF4    ), FADA_PSEA7  (A6V383    ), FADA_PSEAB  (Q02PH7    ), 
FADA_PSEAE  (Q9HZJ3    ), FADA_PSEE4  (Q1I7D5    ), FADA_PSEF5  (Q4KFC3    ), 
FADA_PSEFR  (P28790    ), FADA_PSEHT  (Q3IJ24    ), FADA_PSEMY  (A4XSM9    ), 
FADA_PSEOL  (Q93Q11    ), FADA_PSEP1  (A5W6G9    ), FADA_PSEPF  (Q3K9D9    ), 
FADA_PSEPK  (Q88L01    ), FADA_PSEPU  (Q9R9W0    ), FADA_PSESM  (Q87ZB3    ), 
FADA_PSEU2  (Q4ZRA1    ), FADA_PSEU5  (A4VKA4    ), FADA_PSYA2  (Q4FQC7    ), 
FADA_PSYCK  (Q1Q8K0    ), FADA_PSYWF  (A5WH98    ), FADA_SACD2  (Q21KB1    ), 
FADA_SALCH  (Q57HM7    ), FADA_SALPA  (Q5PKQ3    ), FADA_SALTI  (P0A2H8    ), 
FADA_SALTY  (P0A2H7    ), FADA_SERP5  (A8G8D0    ), FADA_SHEAM  (A1S1I7    ), 
FADA_SHEB5  (A3CYJ3    ), FADA_SHEB8  (A6WH99    ), FADA_SHEDO  (Q12TB5    ), 
FADA_SHEFN  (Q08A40    ), FADA_SHELP  (A3Q8U3    ), FADA_SHEON  (Q8EKS0    ), 
FADA_SHEPC  (A4Y1B5    ), FADA_SHESA  (A0KR49    ), FADA_SHESM  (Q0HPB8    ), 
FADA_SHESR  (Q0I0T4    ), FADA_SHESW  (A1RDW3    ), FADA_SHIBS  (Q31UE3    ), 
FADA_SHIDS  (Q32A20    ), FADA_SHIF8  (Q0SZ35    ), FADA_SHIFL  (Q83PG2    ), 
FADA_SHISS  (Q3YVC2    ), FADA_VIBC3  (A5F464    ), FADA_VIBCH  (Q9KNI0    ), 
FADA_VIBF1  (Q5E8X7    ), FADA_VIBFM  (B5FEW7    ), FADA_VIBPA  (Q87TP0    ), 
FADA_VIBVU  (Q8DDK5    ), FADA_VIBVY  (Q7MQI0    ), FADA_YERE8  (A1JIG3    ), 
FADA_YERP3  (A7FDF1    ), FADA_YERPA  (Q1C2C3    ), FADA_YERPE  (Q8ZAM9    ), 
FADA_YERPN  (Q1CNA0    ), FADA_YERPP  (A4TR28    ), FADA_YERPS  (Q66FR9    ), 
FADI_AERHH  (A0KK76    ), FADI_AERS4  (A4SMT9    ), FADI_CITK8  (A8ADP1    ), 
FADI_CROS8  (A7MH80    ), FADI_ECO24  (A7ZPF9    ), FADI_ECO27  (B7UFZ9    ), 
FADI_ECO45  (B7MGV8    ), FADI_ECO55  (B7LBJ6    ), FADI_ECO57  (Q8XCN9    ), 
FADI_ECO5E  (B5YXY5    ), FADI_ECO7I  (B7NP25    ), FADI_ECO81  (B7MY17    ), 
FADI_ECO8A  (B7M6M3    ), FADI_ECOBW  (C4ZVN3    ), FADI_ECODH  (B1X9L5    ), 
FADI_ECOHS  (A8A2L1    ), FADI_ECOK1  (A1ADI9    ), FADI_ECOL5  (Q0TFA5    ), 
FADI_ECOL6  (Q8FFG3    ), FADI_ECOLC  (B1IXA4    ), FADI_ECOLI  (P76503    ), 
FADI_ECOLU  (B7N5V3    ), FADI_ECOSE  (B6I6Q5    ), FADI_ECOSM  (B1LME8    ), 
FADI_ECOUT  (Q1R971    ), FADI_ENT38  (A4WCW7    ), FADI_ERWT9  (B2VJ10    ), 
FADI_ESCF3  (B7LLC9    ), FADI_KLEP3  (B5XVW1    ), FADI_KLEP7  (A6TC20    ), 
FADI_PECAS  (Q6D2L6    ), FADI_PECCP  (C6DAL8    ), FADI_PHOLL  (Q7N287    ), 
FADI_PSEHT  (Q3IEE3    ), FADI_SALA4  (B5EZS0    ), FADI_SALAR  (A9MJ36    ), 
FADI_SALCH  (Q57LW5    ), FADI_SALDC  (B5FPN2    ), FADI_SALEP  (B5R3S0    ), 
FADI_SALHS  (B4TCA9    ), FADI_SALNS  (B4SZR1    ), FADI_SALPA  (Q5PCX7    ), 
FADI_SALPB  (A9N452    ), FADI_SALPC  (C0PZX5    ), FADI_SALPK  (B5BBA0    ), 
FADI_SALSV  (B4TQC3    ), FADI_SALTI  (Q8Z4Y9    ), FADI_SALTY  (Q8ZNA6    ), 
FADI_SERP5  (A8GH87    ), FADI_SHIB3  (B2TWV5    ), FADI_SHIBS  (Q31YB6    ), 
FADI_SHIDS  (Q32DJ3    ), FADI_SHIF8  (Q0T2E5    ), FADI_SHIFL  (Q83K95    ), 
FADI_SHISS  (Q3YZM1    ), FADI_YERE8  (A1JK23    ), FADI_YERP3  (A7FGK0    ), 
FADI_YERPA  (Q1C659    ), FADI_YERPB  (B2K8J6    ), FADI_YERPE  (Q8ZD46    ), 
FADI_YERPG  (A9R7W9    ), FADI_YERPN  (Q1CHK1    ), FADI_YERPP  (A4TM83    ), 
FADI_YERPS  (Q668V0    ), FADI_YERPY  (B1JGG1    ), NLTP2_CAEEL (G5EDP2    ), 
NLTP_BOVIN  (P07857    ), NLTP_CHICK  (Q07598    ), NLTP_HUMAN  (P22307    ), 
NLTP_MOUSE  (P32020    ), NLTP_RABIT  (O62742    ), NLTP_RAT    (P11915    ), 
PAAJ_ECOLI  (P0C7L2    ), PAAJ_ECOLX  (P0C7L3    ), PCAF_ACIAD  (Q43974    ), 
PCAF_PSEAE  (Q9I6R0    ), PCAF_PSEKB  (Q8VPF1    ), PCAF_PSEPU  (Q51956    ), 
PKSM_BACSU  (P40872    ), PKSR_BACSU  (O31784    ), THIA_CANTR  (Q12598    ), 
THIB_CANTR  (Q04677    ), THIC1_ARATH (Q8S4Y1    ), THIK1_ARATH (Q8LF48    ), 
THIK2_ARATH (Q56WD9    ), THIK5_ARATH (Q570C8    ), THIKA_CANTR (P33290    ), 
THIKA_MOUSE (Q921H8    ), THIKA_RAT   (P21775    ), THIKB_CANTR (P33291    ), 
THIKB_MOUSE (Q8VCH0    ), THIKB_RAT   (P07871    ), THIK_ENCCU  (Q8SVA6    ), 
THIK_HUMAN  (P09110    ), THIK_YARLI  (Q05493    ), THIK_YEAST  (P27796    ), 
THIL1_DICDI (Q86AD9    ), THILA_XENLA (Q6NU46    ), THILB_XENLA (Q6GN02    ), 
THILH_CAEEL (Q22100    ), THIL_ALLVD  (P45369    ), THIL_BOVIN  (Q29RZ0    ), 
THIL_CHRVO  (Q9ZHI1    ), THIL_CUPNH  (P14611    ), THIL_DANRE  (Q6AZA0    ), 
THIL_HUMAN  (P24752    ), THIL_MACFA  (Q8HXY6    ), THIL_MOUSE  (Q8QZT1    ), 
THIL_PARDE  (P54810    ), THIL_RAT    (P17764    ), THIL_RHIME  (P50174    ), 
THIL_SACMO  (P10551    ), THIL_THIVI  (P45363    ), THIL_XENTR  (Q5BKN8    ), 
THIL_YARLI  (Q6L8K7    ), THIL_YEAST  (P41338    ), THIL_ZOORA  (P07097    ), 
THIM_BOVIN  (Q3T0R7    ), THIM_HUMAN  (P42765    ), THIM_MOUSE  (Q8BWT1    ), 
THIM_PONAB  (Q5RES5    ), THIM_RAT    (P13437    ), THLA_CLOAB  (P45359    ), 
THLA_PEPD6  (Q18AR0    ), THLA_STAA3  (Q2FJQ9    ), THLA_STAA8  (Q2G124    ), 
THLA_STAAB  (Q2YVF5    ), THLA_STAAC  (Q5HIU0    ), THLA_STAAM  (Q99WM3    ), 
THLA_STAAN  (Q7A7L2    ), THLA_STAAR  (Q6GJW4    ), THLA_STAAS  (Q6GCB8    ), 
THLA_STAAW  (Q8NY95    ), THLA_STAEQ  (Q5HS07    ), THLA_STAES  (Q8CQN7    ), 
THL_BACSU   (P45855    ), Y0859_MYCTU (O53871    ), YKA3_CAEEL  (P34255    ), 
YQEF_ECOLI  (Q46939    )
» more

UniProtKB/Swiss-Prot
False negative sequences
47 sequences

FADA5_MYCTU (I6XHI4    ), FADI_ALTMD  (B4RTU9    ), FADI_COLP3  (Q47ZB6    ), 
FADI_IDILO  (Q5QXN5    ), FADI_PHOPR  (Q6LTK4    ), FADI_PSEA6  (Q15VA3    ), 
FADI_SHEAM  (A1S7L7    ), FADI_SHEB2  (B8EE97    ), FADI_SHEB5  (A3D685    ), 
FADI_SHEB8  (A6WQ26    ), FADI_SHEB9  (A9KTW7    ), FADI_SHEDO  (Q12P12    ), 
FADI_SHEFN  (Q07ZP7    ), FADI_SHEHH  (B0TL22    ), FADI_SHELP  (A3QFP4    ), 
FADI_SHEON  (Q8ECP6    ), FADI_SHEPA  (A8H5T2    ), FADI_SHEPC  (A4Y898    ), 
FADI_SHEPW  (B8CPY7    ), FADI_SHESA  (A0KV75    ), FADI_SHESH  (A8FTR6    ), 
FADI_SHESM  (Q0HKD2    ), FADI_SHESR  (Q0HWN4    ), FADI_SHESW  (A1RI91    ), 
FADI_SHEWM  (B1KKT1    ), FADI_VIBC3  (A5F2P1    ), FADI_VIBCH  (Q9KT59    ), 
FADI_VIBF1  (Q5E3U0    ), FADI_VIBFM  (B5FGB5    ), FADI_VIBPA  (Q87MM2    ), 
FADI_VIBVU  (Q8DB48    ), FADI_VIBVY  (Q7MIS4    ), THIC2_ARATH (Q9FIK7    ), 
THIC_HUMAN  (Q9BWD1    ), THIC_MOUSE  (Q8CAY6    ), THIC_RAT    (Q5XI22    ), 
VRAB_STAA1  (Q9KWK4    ), VRAB_STAAC  (Q5HIA0    ), VRAB_STAAM  (Q7A2W9    ), 
VRAB_STAAN  (Q7A768    ), VRAB_STAAR  (Q6GJ93    ), VRAB_STAAS  (Q6GBR1    ), 
VRAB_STAAW  (Q7A1P9    ), VRAB_STAEQ  (Q5HRH3    ), VRAB_STAES  (Q8CTR0    ), 
VRAB_STAHJ  (Q4L3Q1    ), YHFS_BACSU  (O07618    )
» more

UniProtKB/Swiss-Prot
'Partial' sequences
3 sequences

THIL_PIG    (P14610    ), THL_CLODI   (P45362    ), THL_CLOPA   (P81347    )

		
UniProtKB/Swiss-Prot
False positive sequences
4 sequences

NODE_RHIME  (P06230    ), NODE_RHIS3  (P72331    ), NOE4_RHIML  (P06231    ), 
STRU3_BPPAJ (P85503    )
» more

PDB
[Detailed view]
36 PDB

1AFW; 1DLU; 1DLV; 1M1T; 1PXT; 1WDK; 1WDL; 1WDM; 2C7Y; 2C7Z; 2D3T; 2IB7; 2IB8; 2IB9; 2IIK; 2VU2; 2WKT; 2WKU; 2WKV; 2WL4; 2WL5; 2WL6; 2WU9; 4B3H; 4B3I; 4B3J; 4C2K; 4DD5; 4NZS; 4O99; 4W61; 4WYR; 4WYS; 4XL2; 5F0V; 5LP7
» more

View entry in original PROSITE format
View entry in raw text format (no links)
Direct ScanProsite submission