Entry: PS00120

General information about the entry

Entry name [info] LIPASE_SER
Accession [info] PS00120
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED; 01-DEC-2004 DATA UPDATE; 15-FEB-2017 INFO UPDATE.
PROSITE Doc. [info] PDOC00110
Associated ProRule [info] PRU10037

Name and characterization of the entry

Description [info] Lipases, serine active site.
Pattern [info]
[LIV]-{KG}-[LIVFY]-[LIVMST]-G-[HYWV]-S-{YAG}-G-[GSTAC].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2017_02 which contains 553'655 sequence entries.


Total number of hits 334 in 334 different sequences
Number of true positive hits 229 in 229 different sequences
Number of 'unknown' hits 27 in 27 different sequences
Number of false positive hits 78 in 78 different sequences
Number of false negative sequences 50
Number of 'partial' sequences 7
Precision (true positives / (true positives + false positives)) 74.59 %
Recall (true positives / (true positives + false negatives)) 82.08 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 1
Site [info] active_site at position 7
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
229 sequences

ATG15_AJECN (A6REI4    ), ATG15_ASHGO (Q75EN3    ), ATG15_ASPFU (Q4X180    ), 
ATG15_ASPNC (A2QGD9    ), ATG15_ASPTN (Q0CXU6    ), ATG15_CANAL (Q5A4N0    ), 
ATG15_CANGA (Q6FPI6    ), ATG15_CRYNB (P0CO61    ), ATG15_CRYNJ (P0CO60    ), 
ATG15_DEBHA (Q6BLM0    ), ATG15_EMENI (Q5B0L1    ), ATG15_KLULA (Q6CU02    ), 
ATG15_LODEL (A5E567    ), ATG15_NEUCR (Q7RYY1    ), ATG15_PASFU (O13444    ), 
ATG15_PICAN (A7KAJ9    ), ATG15_PICGU (A5DC90    ), ATG15_PICST (A3LV34    ), 
ATG15_SCHPO (O13934    ), ATG15_USTMA (Q4PHZ2    ), ATG15_VANPO (A7TG13    ), 
ATG15_YARLI (Q6C2N7    ), ATG15_YEAS7 (A6ZTP2    ), ATG15_YEAST (P25641    ), 
BPHL_HUMAN  (Q86WA6    ), BPHL_MOUSE  (Q8R164    ), CLH0_CHEAL  (Q9LE89    ), 
CLH1_CITSI  (Q9MV14    ), CLH1_CITUN  (Q94LX1    ), DGLA_HUMAN  (Q9Y4D2    ), 
DGLA_MOUSE  (Q6WQJ1    ), DGLA_RAT    (Q5YLM1    ), DGLB_HUMAN  (Q8NCG7    ), 
DGLB_MOUSE  (Q91WC9    ), DGLB_RAT    (P0C1S9    ), ESTD_THEMA  (Q9WYH1    ), 
FAEA_ASPAW  (Q9P979    ), FAEA_ASPFN  (B8NIB8    ), FAEA_ASPNC  (A2QSY5    ), 
FAEA_ASPNG  (O42807    ), FAEA_ASPOR  (Q2UNW5    ), FAEA_ASPTN  (Q0CBM7    ), 
FAEA_ASPTU  (O42815    ), KRAK_DROME  (O18391    ), LCAT_GERGM  (O35840    ), 
LCAT_HUMAN  (P04180    ), LCAT_MOUSE  (P16301    ), LCAT_MYOGA  (O35502    ), 
LCAT_PAPAN  (Q08758    ), LCAT_RABIT  (P53761    ), LCAT_RAT    (P18424    ), 
LDAH_HUMAN  (Q9H6V9    ), LDAH_MOUSE  (Q8BVA5    ), LDAH_PONAB  (Q5R7E8    ), 
LDAH_RAT    (Q5HZX7    ), LDH1_YEAST  (P38139    ), LICH_CROAD  (J3SDX8    ), 
LICH_HUMAN  (P38571    ), LICH_MACFA  (Q4R4S5    ), LICH_MOUSE  (Q9Z0M5    ), 
LIP1_ARATH  (Q71DJ5    ), LIP1_CAEEL  (Q9XTR8    ), LIP1_STAA8  (Q2FUU5    ), 
LIP1_STAAC  (Q5HCM7    ), LIP1_STAAM  (P65288    ), LIP1_STAAN  (P65289    ), 
LIP1_STAAR  (Q6GDD3    ), LIP1_STAAS  (Q6G604    ), LIP1_STAAW  (Q8NUI5    ), 
LIP2_ARATH  (Q67ZU1    ), LIP2_STAA8  (Q2G155    ), LIP2_STAAC  (Q5HJ48    ), 
LIP2_STAAM  (Q99WQ6    ), LIP2_STAAN  (Q7A7P2    ), LIP2_STAAR  (Q6GJZ6    ), 
LIP2_STAAS  (Q6GCF1    ), LIP2_STAAU  (P10335    ), LIP2_STAAW  (Q8NYC2    ), 
LIP3_DROME  (O46108    ), LIPA_ACRAM  (P0CT91    ), LIPA_PSEFL  (P26504    ), 
LIPB_PSEFL  (P41773    ), LIPC_BOVIN  (Q3SZ79    ), LIPC_HUMAN  (P11150    ), 
LIPC_MOUSE  (P27656    ), LIPC_RABIT  (O46559    ), LIPC_RAT    (P07867    ), 
LIPE_AERHY  (P40600    ), LIPE_CROAD  (J3RZ81    ), LIPE_HUMAN  (Q9Y5X9    ), 
LIPE_MOUSE  (Q9WVG5    ), LIPE_RAT    (Q8VBX1    ), LIPG_BOVIN  (Q29458    ), 
LIPG_CANLF  (P80035    ), LIPG_HUMAN  (P07098    ), LIPG_MOUSE  (Q9CPP7    ), 
LIPG_RAT    (P04634    ), LIPJ_HUMAN  (Q5W064    ), LIPK_HUMAN  (Q5VXJ0    ), 
LIPK_MOUSE  (Q8BM14    ), LIPL_BOVIN  (P11151    ), LIPL_CAVPO  (P11153    ), 
LIPL_CHICK  (P11602    ), LIPL_FELCA  (P55031    ), LIPL_HUMAN  (P06858    ), 
LIPL_MOUSE  (P11152    ), LIPL_NEOVI  (O46647    ), LIPL_PAPAN  (P49060    ), 
LIPL_PIG    (P49923    ), LIPL_RAT    (Q06000    ), LIPL_SHEEP  (Q29524    ), 
LIPM_HUMAN  (Q5VYY2    ), LIPM_MOUSE  (Q8K2A6    ), LIPN_HUMAN  (Q5VXI9    ), 
LIPN_MOUSE  (Q3U4B4    ), LIPP_CAVPO  (P50903    ), LIPP_HORSE  (P29183    ), 
LIPP_HUMAN  (P16233    ), LIPP_ICTTR  (O88354    ), LIPP_MOUSE  (Q6P8U6    ), 
LIPP_MYOCO  (Q64425    ), LIPP_PIG    (P00591    ), LIPP_RABIT  (Q02157    ), 
LIPP_RAT    (P27657    ), LIPR1_CANLF (P06857    ), LIPR1_HUMAN (P54315    ), 
LIPR1_MOUSE (Q5BKQ4    ), LIPR1_RAT   (P54316    ), LIPR2_BOVIN (A5PK46    ), 
LIPR2_CAVPO (P81139    ), LIPR2_HUMAN (P54317    ), LIPR2_RAT   (P54318    ), 
LIPR3_HUMAN (Q17RR3    ), LIPV_MYCTU  (L0TC47    ), LIP_BURCE   (P22088    ), 
LIP_BURGL   (Q05489    ), LIP_PSEAE   (P26876    ), LIP_PSEFR   (P08658    ), 
LIP_PSES5   (P25275    ), LIP_PSEU0   (P26877    ), LIP_RHIMI   (P19515    ), 
LIP_RHINI   (P61871    ), LIP_RHIOR   (P61872    ), LIP_STAEP   (P0C0R3    ), 
LIP_STAEQ   (Q5HKP6    ), LIP_STAES   (P0C0R4    ), LIP_STAHY   (P04635    ), 
LIP_THELA   (O59952    ), LIP_VIBCH   (P15493    ), MDLA_PENCA  (P61870    ), 
MDLA_PENCY  (P61869    ), MES14_ARATH (Q9FVW3    ), MGLL_HUMAN  (Q99685    ), 
MGLL_MOUSE  (O35678    ), MGLL_RAT    (Q8R431    ), PA11_DOLMA  (Q06478    ), 
PA11_POLDO  (Q6Q252    ), PA11_VESAF  (P0DMB4    ), PA12_DOLMA  (P53357    ), 
PA12_POLDO  (Q6Q251    ), PA12_VESAF  (P0DMB5    ), PA13_POLDO  (Q6Q250    ), 
PA14_POLDO  (Q6Q249    ), PA1_POLAN   (Q9U6W0    ), PA1_POLPI   (A2VBC4    ), 
PA1_SOLIN   (Q68KK0    ), PA1_VESCR   (P0CH87    ), PA1_VESGE   (Q3ZU95    ), 
PA1_VESMC   (P51528    ), PA1_VESMG   (P0CH47    ), PA1_VESSQ   (P0CH86    ), 
PA1_VESVU   (P49369    ), PAFA2_BOVIN (P79106    ), PAFA2_HUMAN (Q99487    ), 
PAFA2_MOUSE (Q8VDG7    ), PAFA2_RAT   (P83006    ), PAFA_BOVIN  (Q28017    ), 
PAFA_CANLF  (Q28262    ), PAFA_CAVPO  (P70683    ), PAFA_CHICK  (Q90678    ), 
PAFA_HUMAN  (Q13093    ), PAFA_MOUSE  (Q60963    ), PHAZ_PSEOL  (P26495    ), 
PIR7A_ORYSI (A2WYS8    ), PIR7A_ORYSJ (Q0JG98    ), PIR7B_ORYSI (A2WYS7    ), 
PIR7B_ORYSJ (Q0JG99    ), PLA11_ARATH (Q948R1    ), PLA14_ARATH (O23522    ), 
PLA15_ARATH (Q941F1    ), PLA16_ARATH (Q3EBR6    ), PLA17_ARATH (Q9C8J6    ), 
PLA18_ARATH (Q9LNC2    ), PLA19_ARATH (O82274    ), PLA1A_HUMAN (Q53H76    ), 
PLA1A_MOUSE (Q8VI78    ), PLA1A_PONAB (Q5RBQ5    ), PLA1A_RAT   (P97535    ), 
PLA1_ORYSI  (A2WT95    ), PLA1_ORYSJ  (A2ZW16    ), PLA20_ARATH (Q9SJI7    ), 
PLA2_ORYSI  (A2WT96    ), PLA2_ORYSJ  (Q0JKT4    ), PLA3_ORYSI  (A2WTA0    ), 
PLA3_ORYSJ  (Q8RZ40    ), PLA4_ORYSJ  (B9EYD3    ), PLA6_ORYSJ  (Q6F358    ), 
PLA7_ORYSI  (A2Y7R2    ), PLA7_ORYSJ  (Q6F357    ), PLBAC_BACSU (O34705    ), 
PPD_ARATH   (O23512    ), PPD_RAPSA   (Q2V0W1    ), PPME1_BOVIN (Q58DN4    ), 
PPME1_CAEEL (Q9BIB3    ), PPME1_DICDI (Q54TN3    ), PPME1_HUMAN (Q9Y570    ), 
PPME1_MOUSE (Q8BVQ5    ), PPME1_PONAB (Q5R4F9    ), PPT2_DROME  (Q9VKH6    ), 
ROG1_YEAST  (P53118    ), SABP2_TOBAC (Q6RYA0    ), TALLP_MESAU (Q3YBN2    ), 
YD109_YEAST (Q12103    ), YD444_YEAST (Q04093    ), YDK2_SCHPO  (P87109    ), 
YJ77_YEAST  (P47145    ), YJMD_SCHPO  (Q7LKZ6    ), YO059_YEAST (Q08448    ), 
YOR22_YEAST (Q12204    )
» more

UniProtKB/Swiss-Prot
False negative sequences
50 sequences

AT151_PHANO (Q0V1P1    ), ATG15_ASPCL (A1C6D6    ), ATG15_CHAGB (Q2H6M8    ), 
ATG15_COCIM (Q1DZE0    ), ATG15_NEOFI (A1DH10    ), ATG15_PENRW (A7KAM5    ), 
CSE_ARATH   (Q9C942    ), DSEL_ARATH  (O49523    ), EG1_ORYSI   (A2WY00    ), 
EG1_ORYSJ   (Q8S1D9    ), ESTA_BACSU  (P37957    ), ESTB_BACSU  (Q79F14    ), 
LCAT_CHICK  (P53760    ), LCAT_ELIQU  (O35573    ), LCAT_MICMN  (O35724    ), 
LDAH_CHICK  (Q5F477    ), LDAH_DICDI  (Q54LL8    ), LICH_RAT    (Q64194    ), 
LIP1_DROME  (O46107    ), LIP1_MORS1  (P19833    ), LIP1_PSYIM  (Q02104    ), 
LIPHA_XENLA (Q6PA23    ), LIPHB_XENLA (Q641F6    ), LIPH_DANRE  (Q6DBU8    ), 
LIPH_HUMAN  (Q8WWY8    ), LIPH_MOUSE  (Q8CIV3    ), LIPH_RABIT  (Q9BDJ4    ), 
LIPH_RAT    (Q32PY2    ), LIPH_XENTR  (Q5XGE9    ), LIPI_HUMAN  (Q6XZB0    ), 
LIPR2_MOUSE (P17892    ), LIPR2_MYOCO (Q64424    ), LIP_BACSP   (Q5U780    ), 
PAD4_ARATH  (Q9S745    ), PAFA_CAEEL  (Q22943    ), PETH_IDESA  (A0A0K8P6T7), 
PLA12_ARATH (Q9MA46    ), PLA13_ARATH (Q9SIN9    ), PLA1A_BOVIN (Q5E9H0    ), 
PLA1A_DANRE (Q6NYZ4    ), PLA5_ORYSI  (B8A8C9    ), PLA5_ORYSJ  (Q5NAI4    ), 
PLG7_SCHPO  (Q9URV1    ), TGCE1_SCHPO (O74430    ), TGCE2_SCHPO (P78898    ), 
TGCE3_SCHPO (O60095    ), TGL1_YEAST  (P34163    ), YE7A_SCHPO  (O14162    ), 
YEH1_YEAST  (Q07804    ), YEH2_YEAST  (Q07950    )
» more

UniProtKB/Swiss-Prot
'Partial' sequences
7 sequences

LCAT_PIG    (P30930    ), LIPP_FELCA  (P83629    ), LIPT_BURCE  (P29605    ), 
PA11_VESVE  (P0DMB6    ), PA12A_VESVE (P0DMB7    ), PA12B_VESVE (P0DMB8    ), 
PA1_POLGA   (P83542    )
» more

UniProtKB/Swiss-Prot
'Unknown' sequences
27 sequences

AED3_ARATH  (O04496    ), AXE1_HYPJE  (Q99034    ), BST1A_YARLI (Q6C2Z2    ), 
BST1B_YARLI (Q6BZU7    ), BST1C_YARLI (Q6CF60    ), BST1_ASHGO  (Q752Q2    ), 
BST1_ASPFU  (Q4WGM4    ), BST1_ASPOR  (Q2USI0    ), BST1_ASPTN  (Q0CIV4    ), 
BST1_CANAL  (Q59VP0    ), BST1_CHAGB  (Q2H102    ), BST1_COCIM  (Q1DWP9    ), 
BST1_DEBHA  (Q6BRG1    ), BST1_EMENI  (Q5AYC8    ), BST1_KLULA  (Q6CIN9    ), 
BST1_NEUCR  (Q7SAM0    ), BST1_PHANO  (Q0UQV6    ), BST1_SCHPO  (Q9UT41    ), 
BST1_YEAST  (P43571    ), PGAP1_DROME (Q9W495    ), PGAP1_HUMAN (Q75T13    ), 
PGAP1_MOUSE (Q3UUQ7    ), PGAP1_RAT   (Q765A7    ), PGAP1_XENLA (Q66J01    ), 
YL4M_CAEEL  (Q8WT51    ), YP147_YEAST (Q06522    ), YR843_MIMIV (Q5URB6    )
» more

UniProtKB/Swiss-Prot
False positive sequences
78 sequences

ALTH1_PLAF7 (C6KTB7    ), ARGJ_DECAR  (Q47AB5    ), AXE2_TALPU  (O59893    ), 
CHEB2_CARHZ (Q3ADA6    ), CHEB3_RHORT (Q2RRX2    ), CHEB3_VIBCH (Q9KS59    ), 
CHEB_CALS4  (Q8RAZ3    ), CHEB_SALRD  (Q2RZD2    ), CUTI_BOTFU  (Q00298    ), 
CUTI_MONFR  (Q8TGB8    ), ESL2_MYCGE  (Q49418    ), ESL2_MYCPN  (P75311    ), 
ESL3_MYCGE  (Q49421    ), ESL3_MYCPN  (P75268    ), F135B_XENLA (Q641I1    ), 
GLU2A_ORYSJ (B9F676    ), ICT1_YEAST  (Q12385    ), KANL3_RAT   (Q3KR73    ), 
KFA_ASHGO   (Q759T3    ), KFA_CANAL   (Q59ZV4    ), KFA_PICST   (A3GGU3    ), 
KFA_VANPO   (A7TJ85    ), KR231_HUMAN (A1A580    ), MCLN1_HUMAN (Q9GZU1    ), 
MCLN1_MACFA (Q60HE8    ), MCLN1_MOUSE (Q99J21    ), MEX67_SCHPO (Q9Y8G3    ), 
NUOH_FRAAA  (Q0RRW1    ), NUOH_FRACC  (Q2JFL3    ), PDAT_YEAST  (P40345    ), 
PDXD1_BOVIN (A7MBC2    ), PDXD2_HUMAN (Q6P474    ), PHYLO_ARATH (Q15KI9    ), 
PIP_BACCO   (P46541    ), PIP_BREBN   (C0ZKI1    ), PLSX_PSEHT  (Q3IHD8    ), 
PNAE_RAUSE  (Q9SE93    ), PPME1_ASHGO (Q74Z47    ), PPME1_ASPFU (Q4WKB2    ), 
PPME1_ASPOR (Q2URJ0    ), PPME1_CANAL (Q5ALW7    ), PPME1_CANGA (Q6FNL6    ), 
PPME1_CRYNB (P0CO63    ), PPME1_CRYNJ (P0CO62    ), PPME1_DEBHA (Q6BZG3    ), 
PPME1_EMENI (Q5BGN7    ), PPME1_GIBZE (Q4IQC1    ), PPME1_KLULA (Q6CQZ5    ), 
PPME1_NEUCR (Q7SGG8    ), PPME1_RAT   (Q4FZT2    ), PPME1_SCHPO (Q9P7D2    ), 
PPME1_YARLI (Q6CGE1    ), PPME1_YEAST (P38796    ), RPOB_COXB2  (B6J270    ), 
RPOB_COXBN  (A9KD39    ), RPOB_COXBR  (A9NAL4    ), RPOB_COXBU  (P0C8S4    ), 
SFGH_YEAST  (P40363    ), SYE_AMOA5   (B3ERQ7    ), SYE_CARHZ   (Q3A9N9    ), 
SYE_DESAP   (B1I4Z1    ), SYE_DESRM   (A4J0Y7    ), SYE_HELMI   (B0TBU3    ), 
SYE_PELTS   (A5D5L8    ), SYE_SALRD   (Q2S1L8    ), TNR16_HUMAN (P08138    ), 
TNR16_MOUSE (Q9Z0W1    ), TNR16_RAT   (P07174    ), UBE11_ARATH (P93028    ), 
UBE12_ARATH (P92974    ), Y193_HAEIN  (Q57427    ), Y2412_DICDI (Q54DA4    ), 
Y2715_MYCTO (P9WNH2    ), Y2715_MYCTU (P9WNH3    ), Y2734_MYCBO (P0A573    ), 
Y4KF_SINFN  (P55526    ), YELD_SCHPO  (O14244    ), YKM6_SCHPO  (Q9C0Y8    )
» more

PDB
[Detailed view]
95 PDB

1BU8; 1CVL; 1DT3; 1DT5; 1DTE; 1DU4; 1EIN; 1ETH; 1EX9; 1GPL; 1HLG; 1HPL; 1HQD; 1K8Q; 1LGY; 1LPA; 1LPB; 1N8S; 1OIL; 1QGE; 1QOZ; 1RP1; 1TAH; 1TGL; 1TIA; 1TIB; 1TIC; 1USW; 1UWC; 1UZA; 1XKL; 1Y7H; 1Y7I; 1YS1; 1YS2; 2ES4; 2HIH; 2HL6; 2IX9; 2LIP; 2NW6; 2OCG; 2OCI; 2OCK; 2OXE; 2PPL; 2PVS; 3C5V; 3D59; 3D5E; 3F97; 3F98; 3F9C; 3HJU; 3JW8; 3JWE; 3LIP; 3PE6; 3TGL; 4DYH; 4EA6; 4FLF; 4GBG; 4GHW; 4GI1; 4GLB; 4GWL; 4KJX; 4LIP; 4N8S; 4S0X; 4TGL; 4UUQ; 4X96; 4XWG; 4XX1; 4ZGB; 5AP9; 5BV7; 5CH8; 5HK8; 5I8P; 5I9I; 5JAD; 5JAH; 5JAL; 5JAN; 5JAO; 5JAP; 5JAR; 5JAS; 5JAT; 5JAU; 5LIP; 5TGL
» more

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