PROSITE entry PS00120
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Direct ScanProsite submission
General information about the entry
Entry name [info] | LIPASE_SER |
Accession [info] | PS00120 |
Entry type [info] | PATTERN |
Date [info] |
01-APR-1990 CREATED;
01-DEC-2004 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
PROSITE Doc. [info] | PDOC00110 |
Associated ProRule [info] | PRU10037 |
Name and characterization of the entry
Description [info] | Lipases, serine active site. |
Pattern [info] |
[LIV]-{KG}-[LIVFY]-[LIVMST]-G-[HYWV]-S-{YAG}-G-[GSTAC]. |
Numerical results [info]
Total number of hits | 393 in 393 different sequences |
Number of true positive hits | 258 in 258 different sequences |
Number of 'unknown' hits | 28 in 28 different sequences |
Number of false positive hits | 107 in 107 different sequences |
Number of false negative sequences | 62 |
Number of 'partial' sequences | 7 |
Precision (true positives / (true positives + false positives)) | 70.68 % |
Recall (true positives / (true positives + false negatives)) | 80.62 % |
Comments [info]
Taxonomic range [info] | Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses |
Maximum number of repetitions [info] | 1 |
Site [info] | active_site at position 7 |
Version [info] | 1 |
Cross-references [info]
UniProtKB/Swiss-Prot True positive sequences |
258 sequences
ATG15_AJECN (A6REI4), ATG15_ASPFU (Q4X180), ATG15_ASPNC (A2QGD9), ATG15_ASPTN (Q0CXU6), ATG15_CANAL (Q5A4N0), ATG15_CANGA (Q6FPI6), ATG15_CRYNB (P0CO61), ATG15_CRYNJ (P0CO60), ATG15_DEBHA (Q6BLM0), ATG15_EMENI (Q5B0L1), ATG15_EREGS (Q75EN3), ATG15_GIBZE (I1RFN8), ATG15_KLULA (Q6CU02), ATG15_LODEL (A5E567), ATG15_NEUCR (Q7RYY1), ATG15_PASFU (O13444), ATG15_PICAN (A7KAJ9), ATG15_PICGU (A5DC90), ATG15_PICST (A3LV34), ATG15_SCHPO (O13934), ATG15_USTMA (Q4PHZ2), ATG15_VANPO (A7TG13), ATG15_YARLI (Q6C2N7), ATG15_YEAS7 (A6ZTP2), ATG15_YEAST (P25641), BPHL_HUMAN (Q86WA6), BPHL_MOUSE (Q8R164), CLH0_CHEAL (Q9LE89), CLH1_CITSI (Q9MV14), CLH1_CITUN (Q94LX1), DGLA_HUMAN (Q9Y4D2), DGLA_MOUSE (Q6WQJ1), DGLA_RAT(Q5YLM1), DGLB_HUMAN (Q8NCG7), DGLB_MOUSE (Q91WC9), DGLB_RAT(P0C1S9), EDS1C_ARATH (Q9SU72), EDS1L_ARATH (Q9XF23), EDSBC_ARATH (Q9SU71), ESTD_THEMA (Q9WYH1), FAEA_ASPAW (Q9P979), FAEA_ASPFN (B8NIB8), FAEA_ASPNC (A2QSY5), FAEA_ASPNG (O42807), FAEA_ASPOR (Q2UNW5), FAEA_ASPTN (Q0CBM7), FAEA_ASPTU (O42815), FGL2_GIBZE (I1RCD3), FGL3_GIBZE (I1RLL3), KRAK_DROME (O18391), LCAT_GERGM (O35840), LCAT_HUMAN (P04180), LCAT_MOUSE (P16301), LCAT_MYOGA (O35502), LCAT_PAPAN (Q08758), LCAT_RABIT (P53761), LCAT_RAT(P18424), LDAH_DROME (Q9W0H3), LDAH_HUMAN (Q9H6V9), LDAH_MOUSE (Q8BVA5), LDAH_PONAB (Q5R7E8), LDAH_RAT(Q5HZX7), LDH1_YEAST (P38139), LICH_CROAD (J3SDX8), LICH_HUMAN (P38571), LICH_MACFA (Q4R4S5), LICH_MOUSE (Q9Z0M5), LIH1_YEAST (P47145), LIP1_ARATH (Q71DJ5), LIP1_CAEEL (Q9XTR8), LIP1_MALGO (A8PUY1), LIP1_MALRS (P9WEM7), LIP1_STAA8 (Q2FUU5), LIP1_STAAC (Q5HCM7), LIP1_STAAM (P65288), LIP1_STAAN (P65289), LIP1_STAAR (Q6GDD3), LIP1_STAAS (Q6G604), LIP1_STAAW (Q8NUI5), LIP2_ARATH (Q67ZU1), LIP2_STAA8 (Q2G155), LIP2_STAAC (Q5HJ48), LIP2_STAAM (Q99WQ6), LIP2_STAAN (Q7A7P2), LIP2_STAAR (Q6GJZ6), LIP2_STAAS (Q6GCF1), LIP2_STAAU (P10335), LIP2_STAAW (Q8NYC2), LIP3_DROME (O46108), LIPA_PSEFL (P26504), LIPA_SODAL (P0CT91), LIPB_PSEFL (P41773), LIPC_BOVIN (Q3SZ79), LIPC_HUMAN (P11150), LIPC_MOUSE (P27656), LIPC_RABIT (O46559), LIPC_RAT(P07867), LIPE_AERHY (P40600), LIPE_CROAD (J3RZ81), LIPF_BOVIN (Q29458), LIPF_CANLF (P80035), LIPF_HUMAN (P07098), LIPF_MOUSE (Q9CPP7), LIPF_RAT(P04634), LIPG_HUMAN (Q9Y5X9), LIPG_MOUSE (Q9WVG5), LIPG_RAT(Q8VBX1), LIPJ_HUMAN (Q5W064), LIPK_HUMAN (Q5VXJ0), LIPK_MOUSE (Q8BM14), LIPL1_CAEEL (Q93789), LIPL3_CAEEL (O16956), LIPL5_CAEEL (O61866), LIPL_BOVIN (P11151), LIPL_CAVPO (P11153), LIPL_CHICK (P11602), LIPL_FELCA (P55031), LIPL_HUMAN (P06858), LIPL_MOUSE (P11152), LIPL_NEOVI (O46647), LIPL_PAPAN (P49060), LIPL_PIG(P49923), LIPL_RAT(Q06000), LIPL_SHEEP (Q29524), LIPM_HUMAN (Q5VYY2), LIPM_MOUSE (Q8K2A6), LIPN_HUMAN (Q5VXI9), LIPN_MOUSE (Q3U4B4), LIPP_CAVPO (P50903), LIPP_HORSE (P29183), LIPP_HUMAN (P16233), LIPP_ICTTR (O88354), LIPP_MOUSE (Q6P8U6), LIPP_MYOCO (Q64425), LIPP_PIG(P00591), LIPP_RABIT (Q02157), LIPP_RAT(P27657), LIPR1_CANLF (P06857), LIPR1_HUMAN (P54315), LIPR1_MOUSE (Q5BKQ4), LIPR1_RAT (P54316), LIPR2_BOVIN (A5PK46), LIPR2_CAVPO (P81139), LIPR2_HUMAN (P54317), LIPR2_MOUSE (P17892), LIPR2_PIG (D7EZN2), LIPR2_RAT (P54318), LIPR3_HUMAN (Q17RR3), LIPV_MYCTU (L0TC47), LIP_BURCE (P22088), LIP_BURPL (P0DUB8), LIP_PSEAE (P26876), LIP_PSEFR (P08658), LIP_PSEPS (P0DUB9), LIP_PSES5 (P25275), LIP_PSEU0 (P26877), LIP_RHIMI (P19515), LIP_RHINI (P61871), LIP_RHIOR (P61872), LIP_STAEP (P0C0R3), LIP_STAEQ (Q5HKP6), LIP_STAES (P0C0R4), LIP_STAHY (P04635), LIP_THELA (O59952), LIP_VIBCH (P15493), LPL1_YEAST (Q08448), MDL2_MALGO (A8PUY5), MDL3_MALGO (A8PUY3), MDL4_MALGO (A8PUY7), MDL6_MALGO (A8QB34), MDLA_PENCA (P61870), MDLA_PENCY (P61869), MES12_ARATH (Q940H7), MES14_ARATH (Q9FVW3), MES16_ARATH (O23512), MES1_ARATH (Q8S8S9), MES2_ARATH (O80476), MES3_ARATH (O80477), MGLL_HUMAN (Q99685), MGLL_MOUSE (O35678), MGLL_RAT(Q8R431), PA11_DOLMA (Q06478), PA11_POLDO (Q6Q252), PA11_VESAF (P0DMB4), PA12_DOLMA (P53357), PA12_POLDO (Q6Q251), PA12_VESAF (P0DMB5), PA13_POLDO (Q6Q250), PA14_POLDO (Q6Q249), PA1_POLAN (Q9U6W0), PA1_POLPI (A2VBC4), PA1_SOLIN (Q68KK0), PA1_VESBA (A0A0M3KKW3), PA1_VESCR (P0CH87), PA1_VESGE (Q3ZU95), PA1_VESMC (P51528), PA1_VESMG (P0CH47), PA1_VESSQ (P0CH86), PA1_VESVE (C0HLL3), PA1_VESVU (P49369), PAD4_ARATH (Q9S745), PAFA2_BOVIN (P79106), PAFA2_HUMAN (Q99487), PAFA2_MOUSE (Q8VDG7), PAFA2_RAT (P83006), PAFA_BOVIN (Q28017), PAFA_CANLF (Q28262), PAFA_CAVPO (P70683), PAFA_CHICK (Q90678), PAFA_HUMAN (Q13093), PAFA_MOUSE (Q60963), PHAZ_PSEOL (P26495), PIR7A_ORYSI (A2WYS8), PIR7A_ORYSJ (Q0JG98), PIR7B_ORYSI (A2WYS7), PIR7B_ORYSJ (Q0JG99), PLA11_ARATH (Q948R1), PLA14_ARATH (O23522), PLA15_ARATH (Q941F1), PLA16_ARATH (Q3EBR6), PLA17_ARATH (Q9C8J6), PLA18_ARATH (Q9LNC2), PLA19_ARATH (O82274), PLA1A_HUMAN (Q53H76), PLA1A_MOUSE (Q8VI78), PLA1A_PONAB (Q5RBQ5), PLA1A_RAT (P97535), PLA1_ORYSI (A2WT95), PLA1_ORYSJ (A2ZW16), PLA20_ARATH (Q9SJI7), PLA2_ORYSI (A2WT96), PLA2_ORYSJ (Q0JKT4), PLA3_ORYSI (A2WTA0), PLA3_ORYSJ (Q8RZ40), PLA4_ORYSJ (B9EYD3), PLA6_ORYSJ (Q6F358), PLA7_ORYSI (A2Y7R2), PLA7_ORYSJ (Q6F357), PLBAC_BACSU (O34705), PLIP3_ARATH (Q940L4), PPD_RAPSA (Q2V0W1), PPME1_BOVIN (Q58DN4), PPME1_CAEEL (Q9BIB3), PPME1_DICDI (Q54TN3), PPME1_HUMAN (Q9Y570), PPME1_MOUSE (Q8BVQ5), PPME1_PONAB (Q5R4F9), PPT2_DROME (Q9VKH6), ROG1_YEAST (P53118), SABP2_TOBAC (Q6RYA0), TALLP_MESAU (Q3YBN2), VEST1_VESTR (P0DPT0), YD109_YEAST (Q12103), YD444_YEAST (Q04093), YDK2_SCHPO (P87109), YJMD_SCHPO (Q7LKZ6), YOR22_YEAST (Q12204), YP147_YEAST (Q06522)» more
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UniProtKB/Swiss-Prot False negative sequences |
62 sequences
AT151_PHANO (Q0V1P1), ATG15_ASPCL (A1C6D6), ATG15_CHAGB (Q2H6M8), ATG15_COCIM (Q1DZE0), ATG15_NEOFI (A1DH10), ATG15_PENRW (A7KAM5), CSE_ARATH (Q9C942), DSEL_ARATH (O49523), EG1_ORYSI (A2WY00), EG1_ORYSJ (Q8S1D9), ESTA_BACSU (P37957), ESTB_BACSU (Q79F14), FGL1_GIBZE (I1RPD9), LCAT_CHICK (P53760), LCAT_ELIQU (O35573), LCAT_MICMN (O35724), LDAH_CHICK (Q5F477), LDAH_DICDI (Q54LL8), LICH_RAT(Q64194), LIP1_DROME (O46107), LIP1_MORS1 (P19833), LIP1_PSYIM (Q02104), LIP4_MALR7 (A0A3G2S8R6), LIPHA_XENLA (Q6PA23), LIPHB_XENLA (Q641F6), LIPH_DANRE (Q6DBU8), LIPH_HUMAN (Q8WWY8), LIPH_MOUSE (Q8CIV3), LIPH_RABIT (Q9BDJ4), LIPH_RAT(Q32PY2), LIPH_XENTR (Q5XGE9), LIPI_HUMAN (Q6XZB0), LIPL4_CAEEL (Q94252), LIPR2_MYOCO (Q64424), LIP_BACSP (Q5U780), MGLL_MYCTU (O07427), MHEI_NOCS4 (C8CP46), NHL1_FUSSL (Q9HE20), OBL1_ARATH (F4JFU8), OBL1_RICCO (Q5VKJ7), OBL1_TOBAC (A0A1S3ZP85), PA1_DINQU (P0DSI2), PAFA_CAEEL (Q22943), PETH1_AMYMS (P0DX29), PETH_PISS1 (A0A0K8P6T7), PHAZ_TALFU (B2NHN2), PLA12_ARATH (Q9MA46), PLA13_ARATH (Q9SIN9), PLA1A_BOVIN (Q5E9H0), PLA1A_DANRE (Q6NYZ4), PLA5_ORYSI (B8A8C9), PLA5_ORYSJ (Q5NAI4), PLG7_SCHPO (Q9URV1), PLIP1_ARATH (Q7Y220), PLIP2_ARATH (F4HXL0), TGCE1_SCHPO (O74430), TGCE2_SCHPO (P78898), TGCE3_SCHPO (O60095), TGL1_YEAST (P34163), YE7A_SCHPO (O14162), YEH1_YEAST (Q07804), YEH2_YEAST (Q07950)» more |
UniProtKB/Swiss-Prot 'Partial' sequences |
7 sequences
LCAT_PIG(P30930), LIPP_FELCA (P83629), LIPT_BURCE (P29605), PA11_VESVE (P0DMB6), PA12A_VESVE (P0DMB7), PA12B_VESVE (P0DMB8), PA1_POLGA (P83542)» more |
UniProtKB/Swiss-Prot 'Unknown' sequences |
28 sequences
AED3_ARATH (O04496), ATR1_STEAL (A0A8F4SKJ7), AXE1_HYPJE (Q99034), BST1A_YARLI (Q6C2Z2), BST1B_YARLI (Q6BZU7), BST1C_YARLI (Q6CF60), BST1_ASPFU (Q4WGM4), BST1_ASPOR (Q2USI0), BST1_ASPTN (Q0CIV4), BST1_CANAL (Q59VP0), BST1_CHAGB (Q2H102), BST1_COCIM (Q1DWP9), BST1_DEBHA (Q6BRG1), BST1_EMENI (Q5AYC8), BST1_EREGS (Q752Q2), BST1_KLULA (Q6CIN9), BST1_NEUCR (Q7SAM0), BST1_PHANO (Q0UQV6), BST1_SCHPO (Q9UT41), BST1_YEAST (P43571), PGAP1_DROME (Q9W495), PGAP1_HUMAN (Q75T13), PGAP1_MOUSE (Q3UUQ7), PGAP1_RAT (Q765A7), PGAP1_XENLA (Q66J01), TLE3_PSEAE (Q9I6M9), YL4M_CAEEL (Q8WT51), YR843_MIMIV (Q5URB6)» more |
UniProtKB/Swiss-Prot False positive sequences |
107 sequences
5MOAS_ASPTN (Q0CRQ5), AGIA_ASPFN (B8NY88), ALTH1_PLAF7 (C6KTB7), ARGJ_DECAR (Q47AB5), ASCC_ACREG (A0A455R5P9), AXE2_TALPU (O59893), CHEB2_CARHZ (Q3ADA6), CHEB3_RHORT (Q2RRX2), CHEB3_VIBCH (Q9KS59), CHEB_CALS4 (Q8RAZ3), CHEB_SALRD (Q2RZD2), CUTI1_COPCI (B9U443), CUTI1_VERDA (A0A2J8C362), CUTI2_PYRO7 (G4MZV6), CUTI_BOTFU (Q00298), CUTI_MONFR (Q8TGB8), EAT1_ERECY (G8JVR4), EAT1_KLULA (Q6CLY8), EAT1_KLUMD (W0T4A7), EAT1_WICAA (A0A1E3P8S6), EAT1_WICCF (K0KPV8), EAT2_CYBFA (A0A061AYY2), EAT2_CYBJN (A0A1E4S2N7), ESL2_MYCGE (Q49418), ESL2_MYCPN (P75311), ESL3_MYCGE (Q49421), ESL3_MYCPN (P75268), F135B_XENLA (Q641I1), GLU2A_ORYSJ (B9F676), ICT1_YEAST (Q12385), KANL3_RAT (Q3KR73), KFA_CANAL (Q59ZV4), KFA_EREGS (Q759T3), KFA_PICST (A3GGU3), KFA_VANPO (A7TJ85), KR231_HUMAN (A1A580), MCLN1_HUMAN (Q9GZU1), MCLN1_MACFA (Q60HE8), MCLN1_MOUSE (Q99J21), MEX67_SCHPO (Q9Y8G3), NUOH_FRAAA (Q0RRW1), NUOH_FRACC (Q2JFL3), PDAT_YEAST (P40345), PDXD1_BOVIN (A7MBC2), PDXD2_HUMAN (Q6P474), PETH1_THEAE (D4Q9N1), PETH1_THECS (E9LVH8), PETH1_THEFU (G8GER6), PETH1_THEFY (Q47RJ7), PETH2_THEAE (F7IX06), PETH2_THECS (E9LVH9), PETH2_THEFU (Q6A0I4), PETH2_THEFY (Q47RJ6), PG043_MONPV (A0A7H0DN16), PHYLO_ARATH (Q15KI9), PIP_BREBN (C0ZKI1), PIP_HEYCO (P46541), PKBA_EMENI (Q5AZ32), PLSX_PSET1 (Q3IHD8), PMT2_CANAL (Q5ADM9), PNAE_RAUSE (Q9SE93), PPME1_ASPFU (Q4WKB2), PPME1_ASPOR (Q2URJ0), PPME1_CANAL (Q5ALW7), PPME1_CANGA (Q6FNL6), PPME1_CRYNB (P0CO63), PPME1_CRYNJ (P0CO62), PPME1_DEBHA (Q6BZG3), PPME1_EMENI (Q5BGN7), PPME1_EREGS (Q74Z47), PPME1_GIBZE (Q4IQC1), PPME1_KLULA (Q6CQZ5), PPME1_NEUCR (Q7SGG8), PPME1_RAT (Q4FZT2), PPME1_SCHPO (Q9P7D2), PPME1_YARLI (Q6CGE1), PPME1_YEAST (P38796), PREU3_PREIS (P9WET6), PREU6_PREIS (P9WET2), RPOB_COXB2 (B6J270), RPOB_COXBN (A9KD39), RPOB_COXBR (A9NAL4), RPOB_COXBU (P0C8S4), SFGH_YEAST (P40363), SIDJ_ASPFU (Q4WF56), SYE_AMOA5 (B3ERQ7), SYE_CARHZ (Q3A9N9), SYE_DESAP (B1I4Z1), SYE_DESRM (A4J0Y7), SYE_HELMI (B0TBU3), SYE_PELTS (A5D5L8), SYE_SALRD (Q2S1L8), TNR16_HUMAN (P08138), TNR16_MOUSE (Q9Z0W1), TNR16_RAT (P07174), TRI12_FUSSP (Q9C1B3), TRI12_TRIAR (G0KYA8), UBE11_ARATH (P93028), UBE12_ARATH (P92974), Y193_HAEIN (Q57427), Y2412_DICDI (Q54DA4), Y2715_MYCTO (P9WNH2), Y2715_MYCTU (P9WNH3), Y2734_MYCBO (P0A573), Y4KF_SINFN (P55526), YELD_SCHPO (O14244), YKM6_SCHPO (Q9C0Y8)» more |
PDB [Detailed view] |
160 PDB
1BU8; 1CVL; 1DT3; 1DT5; 1DTE; 1DU4; 1EIN; 1ETH; 1EX9; 1GPL; 1HLG; 1HPL; 1HQD; 1K8Q; 1LGY; 1LPA; 1LPB; 1N8S; 1OIL; 1QGE; 1QOZ; 1RP1; 1TAH; 1TGL; 1TIA; 1TIB; 1TIC; 1USW; 1UWC; 1UZA; 1XKL; 1Y7H; 1Y7I; 1YS1; 1YS2; 2ES4; 2HIH; 2HL6; 2IX9; 2LIP; 2NW6; 2OCG; 2OCI; 2OCK; 2OXE; 2PPL; 2PVS; 3C5V; 3D59; 3D5E; 3F96; 3F97; 3F98; 3F9C; 3HJU; 3JW8; 3JWE; 3LIP; 3PE6; 3TGL; 3UUE; 3UUF; 4DYH; 4EA6; 4FLF; 4GBG; 4GHW; 4GI1; 4GLB; 4GWL; 4KJX; 4LIP; 4N8S; 4NFU; 4QNN; 4S0X; 4TGL; 4UUQ; 4X96; 4XWG; 4XX1; 4ZGB; 4ZRD; 4ZRE; 5AP9; 5BV7; 5CH8; 5GW8; 5HK8; 5I8P; 5I9I; 5JAD; 5JAH; 5JAL; 5JAN; 5JAO; 5JAP; 5JAR; 5JAS; 5JAT; 5JAU; 5LIP; 5LP1; 5LYY; 5LZ2; 5LZ4; 5LZ5; 5LZ7; 5LZ8; 5LZ9; 5TGL; 5TXF; 5YE7; 5YE8; 5YE9; 5YEA; 5ZUN; 6AX1; 6BQ0; 6E7K; 6HW1; 6I8G; 6I8H; 6M06; 6M07; 6M08; 6MVD; 6O8V; 6O9F; 6OAU; 6OAZ; 6OB0; 6OR3; 6OSZ; 6Q6Z; 6QPP; 6QPR; 6U7M; 6V7N; 6XOK; 6XRV; 6XS3; 7APN; 7APP; 7L4T; 7L4U; 7L4W; 7L50; 7PRM; 7SPR; 7XDD; 7XEY; 7XJP; 7ZPG; 8AQF; 8ERL; 8PTC; 8PTQ; 8PTR; 8S9R » more |