Entry: PS00122

General information about the entry

Entry name [info] CARBOXYLESTERASE_B_1
Accession [info] PS00122
Entry type [info] PATTERN
Date [info] APR-1990 (CREATED); NOV-1995 (DATA UPDATE); MAR-2015 (INFO UPDATE).
PROSITE Doc. [info] PDOC00112
Associated ProRule [info] PRU10039

Name and characterization of the entry

Description [info] Carboxylesterases type-B serine active site.
Pattern [info]

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2015_05 which contains 548'454 sequence entries.

Total number of hits 114 in 114 different sequences
Number of true positive hits 112 in 112 different sequences
Number of 'unknown' hits
Number of false positive hits 2 in 2 different sequences
Number of false negative sequences 4
Number of 'partial' sequences 14
Precision (true positives / (true positives + false positives)) 98.25 %
Recall (true positives / (true positives + false negatives)) 96.55 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 1
Site [info] active_site at position 11
Version [info] 1

Cross-references [info]

True positive sequences
112 sequences

ACE1_CAEBR  (Q27459), ACE1_CAEEL  (P38433), ACE4_CAEBR  (Q9NDG8), 
ACES_ANOGA  (Q869C3), ACES_ANOST  (P56161), ACES_BOVIN  (P23795), 
ACES_BUNFA  (Q92035), ACES_CHICK  (P36196), ACES_CULPI  (Q86GC8), 
ACES_DANRE  (Q9DDE3), ACES_DROME  (P07140), ACES_ELEEL  (O42275), 
ACES_FELCA  (O62763), ACES_HUMAN  (P22303), ACES_LEPDE  (Q27677), 
ACES_MOUSE  (P21836), ACES_MYXGL  (Q92081), ACES_RABIT  (Q29499), 
ACES_RAT    (P37136), ACES_TORCA  (P04058), ACES_TORMA  (P07692), 
CEL_BOVIN   (P30122), CEL_HUMAN   (P19835), CEL_MOUSE   (Q64285), 
CEL_RAT     (P07882), CES1D_MOUSE (Q8VCT4), CES1D_RAT   (P16303), 
CHLE1_BRALA (Q95000), CHLE2_BRALA (Q95001), CHLE_BOVIN  (P32749), 
CHLE_CANFA  (P32750), CHLE_FELCA  (O62760), CHLE_HORSE  (P81908), 
CHLE_HUMAN  (P06276), CHLE_MACMU  (P32751), CHLE_MIMIV  (Q5UR02), 
CHLE_MOUSE  (Q03311), CHLE_PANTT  (O62761), CHLE_PIG    (P32752), 
CHLE_RABIT  (P21927), CHLE_SHEEP  (P32753), CRYS_DICDI  (P21837), 
D2_DICDI    (P18142), EST1C_MOUSE (P23953), EST1C_RAT   (P10959), 
EST1E_MOUSE (Q64176), EST1E_RAT   (Q63108), EST1_CAEBR  (Q04456), 
EST1_CAEEL  (Q04457), EST1_CULPI  (P16854), EST1_HUMAN  (P23141), 
EST1_MACFA  (O46421), EST1_MESAU  (Q64419), EST1_MOUSE  (Q8VCC2), 
EST1_PIG    (Q29550), EST1_RABIT  (P12337), EST1_THEFU  (P86325), 
EST2E_MOUSE (Q8BK48), EST2_CAEEL  (Q07085), EST2_HUMAN  (O00748), 
EST2_RABIT  (P14943), EST3A_MOUSE (Q63880), EST3B_MOUSE (Q8VCU1), 
EST4A_HUMAN (Q5XG92), EST4A_MOUSE (Q8R0W5), EST4_RAT    (Q64573), 
EST5A_CANFA (Q6AW47), EST5A_DROMI (O16168), EST5A_DROPE (O16173), 
EST5A_DROPS (P25727), EST5A_FELCA (Q8I034), EST5A_HUMAN (Q6NT32), 
EST5B_DROMI (O16170), EST5B_DROPE (O16172), EST5B_DROPS (P25726), 
EST5C_DROMI (O16169), EST5C_DROPE (O16171), EST5C_DROPS (P25725), 
EST5_RAT    (Q63010), EST6_APIME  (B2D0J5), EST6_DROMA  (P47982), 
EST6_DROME  (P08171), EST6_DROSI  (Q08662), ESTE_MYZPE  (P35501), 
ESTF_MYZPE  (P35502), ESTJ_HELVI  (P12992), ESTP_DROME  (P18167), 
ESTS_DROVI  (Q05487), FUMD_SPHMC  (D2D3B6), LIP1_CANRU  (P20261), 
LIP1_GEOCN  (P17573), LIP1_GEOFE  (P79066), LIP1_YARLI  (Q99156), 
LIP2_CANRU  (P32946), LIP2_GEOCN  (P22394), LIP3_CANRU  (P32947), 
LIP3_YARLI  (Q96VC9), LIP4_CANRU  (P32948), LIP5_CANRU  (P32949), 
PCD_ARTOX   (Q01470), PNBA_BACSU  (P37967), SASB_ANAPL  (Q04791), 
YC7C_SCHPO  (O94493)
» More

False negative sequences
4 sequences

» More

'Partial' sequences
14 sequences

ACES_NAJOX  (Q7LZG1), EST1_SCHGA  (P81429), EST2_CULPI  (P21370), 
EST4_DROMO  (P10094), EST5_DROMO  (P10095), ESTA_SCHGA  (P81012), 
ESTB_SCHGA  (P81011), ESTJ_MANSE  (P19985), JHEA_TRINI  (P30809), 
JHEB_TRINI  (P30810), PMCH_RAT    (P80250)
» More

False positive sequences
2 sequences


[Detailed view]
207 PDB

1ACJ; 1ACL; 1AKN; 1AMN; 1AQL; 1AX9; 1B41; 1C2B; 1C2O; 1C7I; 1C7J; 1CFJ; 1CLE; 1CRL; 1DX4; 1DX6; 1E3Q; 1E66; 1EA5; 1EEA; 1EVE; 1F6W; 1F8U; 1FSS; 1GPK; 1GPN; 1GQR; 1GQS; 1GZ7; 1H22; 1H23; 1HBJ; 1J06; 1J07; 1JJB; 1JMY; 1K4Y; 1KU6; 1LLF; 1LPM; 1LPN; 1LPO; 1LPP; 1LPS; 1MAA; 1MAH; 1MX1; 1MX5; 1MX9; 1N5M; 1N5R; 1OCE; 1ODC; 1P0I; 1P0M; 1P0P; 1P0Q; 1Q83; 1Q84; 1QE3; 1QID; 1QIE; 1QIF; 1QIG; 1QIH; 1QII; 1QIJ; 1QIK; 1QIM; 1QO9; 1QON; 1QTI; 1SOM; 1THG; 1TRH; 1U65; 1UT6; 1VOT; 1VXO; 1VXR; 1W4L; 1W6R; 1W75; 1W76; 1XLU; 1XLV; 1XLW; 1YA4; 1YA8; 1YAH; 1YAJ; 1ZGB; 1ZGC; 2ACE; 2ACK; 2BAG; 2BCE; 2C0P; 2C0Q; 2C4H; 2C5F; 2C5G; 2CEK; 2CKM; 2CMF; 2DQY; 2DQZ; 2DR0; 2GYU; 2GYV; 2GYW; 2H7C; 2H9Y; 2HA0; 2HA2; 2HA3; 2HRQ; 2HRR; 2J3D; 2J3Q; 2J4C; 2J4F; 2JEY; 2PM8; 2V96; 2V97; 2V98; 2VA9; 2VJA; 2VJB; 2VJC; 2VJD; 2VQ6; 2VT6; 2VT7; 2W6C; 2W9I; 2WFZ; 2WG0; 2WG1; 2WG2; 2WHR; 2WID; 2WIF; 2WIG; 2WIJ; 2WIK; 2WIL; 2WLS; 2WSL; 2XI4; 2XMB; 2XMC; 2XMD; 2XMG; 2XQF; 2XQG; 2XQI; 2XQJ; 2XQK; 2XUD; 2XUF; 2XUG; 2XUH; 2XUI; 2XUJ; 2XUK; 2XUO; 2XUP; 2XUQ; 3I6M; 3I6Z; 3K9B; 3LII; 3M3D; 3O9M; 3RAR; 3ZV7; 4A16; 4A23; 4AB1; 4AQD; 4ARA; 4ARB; 4B7Z; 4B80; 4B81; 4B82; 4B83; 4B84; 4B85; 4BBZ; 4BC0; 4BC1; 4BDS; 4BDT; 4BTL; 4EY4; 4EY5; 4EY6; 4EY7; 4EY8; 4M0E; 4M0F; 4QWW; 4TPK; 4TVK
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