Entry: PS00122

General information about the entry

Entry name [info] CARBOXYLESTERASE_B_1
Accession [info] PS00122
Entry type [info] PATTERN
Date [info] APR-1990 (CREATED); NOV-1995 (DATA UPDATE); MAY-2016 (INFO UPDATE).
PROSITE Doc. [info] PDOC00112
Associated ProRule [info] PRU10039

Name and characterization of the entry

Description [info] Carboxylesterases type-B serine active site.
Pattern [info]
F-[GR]-G-x(4)-[LIVM]-x-[LIV]-x-G-x-S-[STAG]-G.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2016_06 which contains 551'385 sequence entries.


Total number of hits 116 in 116 different sequences
Number of true positive hits 114 in 114 different sequences
Number of 'unknown' hits 0
Number of false positive hits 2 in 2 different sequences
Number of false negative sequences 4
Number of 'partial' sequences 14
Precision (true positives / (true positives + false positives)) 98.28 %
Recall (true positives / (true positives + false negatives)) 96.61 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 1
Site [info] active_site at position 11
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
114 sequences

ACE1_CAEBR  (Q27459    ), ACE1_CAEEL  (P38433    ), ACE4_CAEBR  (Q9NDG8    ), 
ACES_ANOGA  (Q869C3    ), ACES_ANOST  (P56161    ), ACES_BOVIN  (P23795    ), 
ACES_BUNFA  (Q92035    ), ACES_CHICK  (P36196    ), ACES_CULPI  (Q86GC8    ), 
ACES_DANRE  (Q9DDE3    ), ACES_DROME  (P07140    ), ACES_ELEEL  (O42275    ), 
ACES_FELCA  (O62763    ), ACES_HUMAN  (P22303    ), ACES_LEPDE  (Q27677    ), 
ACES_MOUSE  (P21836    ), ACES_MYXGL  (Q92081    ), ACES_RABIT  (Q29499    ), 
ACES_RAT    (P37136    ), ACES_TETCF  (P04058    ), ACES_TORMA  (P07692    ), 
CEL_BOVIN   (P30122    ), CEL_HUMAN   (P19835    ), CEL_MOUSE   (Q64285    ), 
CEL_RAT     (P07882    ), CES1D_MOUSE (Q8VCT4    ), CES1D_RAT   (P16303    ), 
CHLE1_BRALA (Q95000    ), CHLE2_BRALA (Q95001    ), CHLE_BOVIN  (P32749    ), 
CHLE_CANLF  (P32750    ), CHLE_FELCA  (O62760    ), CHLE_HORSE  (P81908    ), 
CHLE_HUMAN  (P06276    ), CHLE_MACMU  (P32751    ), CHLE_MIMIV  (Q5UR02    ), 
CHLE_MOUSE  (Q03311    ), CHLE_PANTT  (O62761    ), CHLE_PIG    (P32752    ), 
CHLE_RABIT  (P21927    ), CHLE_SHEEP  (P32753    ), CRYS_DICDI  (P21837    ), 
D2_DICDI    (P18142    ), EST1C_MOUSE (P23953    ), EST1C_RAT   (P10959    ), 
EST1E_MOUSE (Q64176    ), EST1E_RAT   (Q63108    ), EST1_CAEBR  (Q04456    ), 
EST1_CAEEL  (Q04457    ), EST1_CULPI  (P16854    ), EST1_HUMAN  (P23141    ), 
EST1_MACFA  (O46421    ), EST1_MESAU  (Q64419    ), EST1_MOUSE  (Q8VCC2    ), 
EST1_PIG    (Q29550    ), EST1_RABIT  (P12337    ), EST1_THEFU  (P86325    ), 
EST1_THEFY  (Q47M62    ), EST2A_MOUSE (Q8QZR3    ), EST2C_MOUSE (Q91WG0    ), 
EST2E_MOUSE (Q8BK48    ), EST2_CAEEL  (Q07085    ), EST2_HUMAN  (O00748    ), 
EST2_RABIT  (P14943    ), EST3A_MOUSE (Q63880    ), EST3B_MOUSE (Q8VCU1    ), 
EST3_HUMAN  (Q6UWW8    ), EST3_PONAB  (Q5RCL7    ), EST4A_BOVIN (P0C6R3    ), 
EST4A_HUMAN (Q5XG92    ), EST4A_MOUSE (Q8R0W5    ), EST4_RAT    (Q64573    ), 
EST5A_CANLF (Q6AW47    ), EST5A_DROMI (O16168    ), EST5A_DROPE (O16173    ), 
EST5A_DROPS (P25727    ), EST5A_FELCA (Q8I034    ), EST5A_HUMAN (Q6NT32    ), 
EST5A_MOUSE (Q6AW46    ), EST5A_RAT   (Q5GRG2    ), EST5A_SHEEP (Q3T930    ), 
EST5B_DROMI (O16170    ), EST5B_DROPE (O16172    ), EST5B_DROPS (P25726    ), 
EST5C_DROMI (O16169    ), EST5C_DROPE (O16171    ), EST5C_DROPS (P25725    ), 
EST5_RAT    (Q63010    ), EST6_APIME  (B2D0J5    ), EST6_DROMA  (P47982    ), 
EST6_DROME  (P08171    ), EST6_DROSI  (Q08662    ), ESTE_MYZPE  (P35501    ), 
ESTF_MYZPE  (P35502    ), ESTJ_HELVI  (P12992    ), ESTP_DROME  (P18167    ), 
ESTS_DROVI  (Q05487    ), FUMD_SPHMC  (D2D3B6    ), LIP1_ARTBC  (D4ASH1    ), 
LIP1_CANRU  (P20261    ), LIP1_GEOCN  (P17573    ), LIP1_GEOFE  (P79066    ), 
LIP1_YARLI  (Q99156    ), LIP2_CANRU  (P32946    ), LIP2_GEOCN  (P22394    ), 
LIP3_ARTBC  (D4B1N9    ), LIP3_CANRU  (P32947    ), LIP3_YARLI  (Q96VC9    ), 
LIP4_CANRU  (P32948    ), LIP5_CANRU  (P32949    ), PCD_ARTOX   (Q01470    ), 
PNBA_BACSU  (P37967    ), SASB_ANAPL  (Q04791    ), YC7C_SCHPO  (O94493    )
» more

UniProtKB/Swiss-Prot
False negative sequences
4 sequences

ACES_TRILK  (W4VSJ0    ), CES1P_HUMAN (Q9UKY3    ), ESTE_HVAVE  (A4KX74    ), 
ESTE_SFAVA  (Q0E588    )
» more

UniProtKB/Swiss-Prot
'Partial' sequences
14 sequences

ACES_CULPP  (Q867X3    ), ACES_CULQU  (Q867X2    ), ACES_CULTO  (Q86GC9    ), 
ACES_NAJOX  (Q7LZG1    ), EST1_SCHGA  (P81429    ), EST2_CULPI  (P21370    ), 
EST4_DROMO  (P10094    ), EST5_DROMO  (P10095    ), ESTA_SCHGA  (P81012    ), 
ESTB_SCHGA  (P81011    ), ESTJ_MANSE  (P19985    ), JHEA_TRINI  (P30809    ), 
JHEB_TRINI  (P30810    ), PMCH_RAT    (P80250    )
» more

UniProtKB/Swiss-Prot
False positive sequences
2 sequences

ICME_ARATH  (Q94AS5    ), ICML2_ARATH (Q1PET6    )

		
PDB
[Detailed view]
227 PDB

1ACJ; 1ACL; 1AKN; 1AMN; 1AQL; 1AX9; 1B41; 1C2B; 1C2O; 1C7I; 1C7J; 1CFJ; 1CLE; 1CRL; 1DX4; 1DX6; 1E3Q; 1E66; 1EA5; 1EEA; 1EVE; 1F6W; 1F8U; 1FSS; 1GPK; 1GPN; 1GQR; 1GQS; 1GZ7; 1H22; 1H23; 1HBJ; 1J06; 1J07; 1JJB; 1JMY; 1K4Y; 1KU6; 1LLF; 1LPM; 1LPN; 1LPO; 1LPP; 1LPS; 1MAA; 1MAH; 1MX1; 1MX5; 1MX9; 1N5M; 1N5R; 1OCE; 1ODC; 1P0I; 1P0M; 1P0P; 1P0Q; 1Q83; 1Q84; 1QE3; 1QID; 1QIE; 1QIF; 1QIG; 1QIH; 1QII; 1QIJ; 1QIK; 1QIM; 1QO9; 1QON; 1QTI; 1SOM; 1THG; 1TRH; 1U65; 1UT6; 1VOT; 1VXO; 1VXR; 1W4L; 1W6R; 1W75; 1W76; 1XLU; 1XLV; 1XLW; 1YA4; 1YA8; 1YAH; 1YAJ; 1ZGB; 1ZGC; 2ACE; 2ACK; 2BAG; 2BCE; 2C0P; 2C0Q; 2C4H; 2C5F; 2C5G; 2CEK; 2CKM; 2CMF; 2DQY; 2DQZ; 2DR0; 2GYU; 2GYV; 2GYW; 2H7C; 2H9Y; 2HA0; 2HA2; 2HA3; 2HRQ; 2HRR; 2J3D; 2J3Q; 2J4C; 2J4F; 2JEY; 2PM8; 2V96; 2V97; 2V98; 2VA9; 2VJA; 2VJB; 2VJC; 2VJD; 2VQ6; 2VT6; 2VT7; 2W6C; 2WFZ; 2WG0; 2WG1; 2WG2; 2WHR; 2WID; 2WIF; 2WIG; 2WIJ; 2WIK; 2WIL; 2WLS; 2WSL; 2XI4; 2XMB; 2XMC; 2XMD; 2XMG; 2XQF; 2XQG; 2XQI; 2XQJ; 2XQK; 2XUD; 2XUF; 2XUG; 2XUH; 2XUI; 2XUJ; 2XUK; 2XUO; 2XUP; 2XUQ; 3I6M; 3I6Z; 3K9B; 3LII; 3M3D; 3O9M; 3RAR; 3ZV7; 4A16; 4A23; 4AB1; 4AQD; 4ARA; 4ARB; 4B7Z; 4B80; 4B81; 4B82; 4B83; 4B84; 4B85; 4BBZ; 4BC0; 4BC1; 4BDS; 4BDT; 4BTL; 4EY4; 4EY5; 4EY6; 4EY7; 4EY8; 4M0E; 4M0F; 4PQE; 4QWW; 4TPK; 4TVK; 4W63; 4X3C; 4XII; 5A7F; 5A7H; 5BWB; 5BWC; 5DLP; 5DTI; 5E2I; 5E4J; 5E4T; 5EHN; 5EHQ; 5EHZ; 5EIA; 5EIE; 5EIH; 5FKJ; 5FOQ
» more

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