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| Entry: PS00136 |
| General information about the entry | |
|---|---|
| Entry name | SUBTILASE_ASP |
| Accession number | PS00136 |
| Entry type | PATTERN |
| Date | APR-1990 (CREATED); DEC-2004 (DATA UPDATE); MAR-2013 (INFO UPDATE). |
| PROSITE Documentation | PDOC00125 |
| Associated ProRule | PRU10080 |
| Name and characterization of the entry | |
| Description | Serine proteases, subtilase family, aspartic acid active site. |
| Pattern | [STAIV]-{ERDL}-[LIVMF]-[LIVM]-D-[DSTA]-G-[LIVMFC]-x(2,3)-[DNH]. |
| Numerical results | |
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| Comments | |
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| Cross-references | |
| UniProtKB/Swiss-Prot | True positive hits:AEP_YARLI (P09230), ALP_ACRCH (P29118), ALP_FUSCU (P83610), ALP_HYPAT (Q03420), ALP_LECPS (Q68GV9), APRX_BACSU (O31788), AQL1_THEAQ (P08594), ASPA_AERSA (P31339), BLI4_CAEEL (P51559), BPRV_DICNO (P42779), BPRX_DICNO (P42780), C5AP_STRP1 (P58099), C5AP_STRP3 (P0DD34), C5AP_STRP6 (Q5X9R0), C5AP_STRP8 (Q8NZ80), C5AP_STRPQ (P0DD35), C5AP_STRPY (P15926), CUDP_METAN (P29138), ELYA_BACAO (P27693), ELYA_BACCS (P41362), ELYA_BACHD (P41363), ELYA_BACYA (P20724), EPIP_STAEP (P30199), EXPR_XANCP (P23314), FUR11_DROME (P26016), FUR1C_DROME (P30430), FUR2_DROME (P30432), FURI1_XENLA (P29119), FURIN_BOVIN (Q28193), FURIN_HUMAN (P09958), FURIN_MOUSE (P23188), FURIN_RAT (P23377), ISP1_BACSU (P11018), ISP6_SCHPO (P40903), ISP_BACCS (P29140), ISP_PAEPO (P29139), KEX1A_KLULA (P09231), KEX2_YEAST (P13134), KRP1_SCHPO (Q09175), NEC1_BOVIN (Q9GLR1), NEC1_HUMAN (P29120), NEC1_MOUSE (P63239), NEC1_MUSCO (P63240), NEC1_RAT (P28840), NEC2_BOVIN (Q9GLR0), NEC2_HUMAN (P16519), NEC2_MOUSE (P21661), NEC2_PIG (Q03333), NEC2_PONAB (Q5REC2), NEC2_RAT (P28841), NECA_HYDVU (P29146), NECB_HYDVU (P29145), NISP_LACLL (Q07596), NVSP_ALIVI (P83433), ORYZ_ASPCL (A1CIA7), ORYZ_ASPFC (B0Y708), ORYZ_ASPFN (B8N106), ORYZ_ASPFU (P28296), ORYZ_ASPOR (P12547), ORYZ_EMENI (Q00208), ORYZ_NEOFI (A1CWF3), P1P_LACLC (P16271), P2P_LACLC (P15293), P2P_LACPA (Q02470), P3P_LACLS (P15292), PCSK4_HUMAN (Q6UW60), PCSK4_MOUSE (P29121), PCSK4_RAT (Q78EH2), PCSK5_HUMAN (Q92824), PCSK5_MOUSE (Q04592), PCSK5_RAT (P41413), PCSK6_HUMAN (P29122), PCSK6_RAT (Q63415), PIIS_ACHLY (P81719), PLS_PYRFU (P72186), PRCA_ANAVT (P23916), PRCA_NOSS1 (Q59149), PROA_VIBAL (P16588), PRTB_YEAST (P09232), PRTK_TRIAL (P06873), PRTM_BACSK (Q99405), PRTR_TRIAL (P23653), PRTT_TRIAL (P20015), PSP3_SCHPO (Q9UTS0), RRT12_YEAST (P25381), SEPR_THESR (P80146), SMP1_MAGPO (Q9Y778), SPAZ_ARTOA (G1X8P8), SPAZ_ARTOL (G3FNQ9), SPL1_ENCCU (Q8SQJ3), SUB10_ARTBC (D4AQG0), SUB10_TRIVH (D4DIS6), SUB2A_COCP7 (C5P6D1), SUB2B_COCP7 (C5P906), SUB2C_COCP7 (C5NZ70), SUB2_ARTBC (D4AZ75), SUB2_ARTBE (Q64K35), SUB2_ARTGP (E4UZP9), SUB2_ARTOC (C5G168), SUB2_ARTOT (Q8J0D8), SUB2_TRIEQ (B6VA85), SUB2_TRIRU (Q69F57), SUB2_TRITO (B8XGQ5), SUB2_TRIVC (Q5VJ76), SUB2_TRIVH (D4DLI5), SUB4B_COCP7 (C5NZT2), SUB5_ARTBC (D4B194), SUB5_ARTBE (Q64K32), SUB5_ARTGP (E4V2L6), SUB5_ARTOC (C5G1D1), SUB5_TRIEQ (B6VA87), SUB5_TRIRU (Q69F34), SUB5_TRITO (B8XGQ8), SUB5_TRIVC (Q5VJ73), SUB5_TRIVH (D4D0F5), SUB6_ARTBC (D4ALV9), SUB6_ARTBE (Q64K31), SUB6_ARTGP (E4V4J8), SUB6_ARTOC (C5FQI3), SUB6_TRIEQ (A1XIH0), SUB6_TRIRU (Q9UW97), SUB6_TRISD (A1XIH1), SUB6_TRISH (Q8J077), SUB6_TRITO (Q3ZEJ8), SUB6_TRIVC (Q5VJ72), SUB6_TRIVH (D4D5H3), SUB7A_COCP7 (C5PGK9), SUB7C_COCP7 (C5NZ69), SUB7D_COCP7 (C5P9H3), SUBB_BACLE (P29599), SUBD_BACLI (P00781), SUBE_BACSU (P16396), SUBN_BACNA (P35835), SUBS_BACLE (P29600), SUBT_BACAM (P00782), SUBT_BACLI (P00780), SUBT_BACPU (P07518), SUBT_BACS9 (P28842), SUBT_BACSA (P00783), SUBT_BACSU (P04189), SUBT_GEOSE (P29142), SUBV_BACSU (P29141), THES_BACSJ (Q45670), THET_THEVU (P04072), TKSU_PYRKO (P58502), XPR6_YARLI (P42781), XSP1_ARATH (Q9LLL8), YSP3_YEAST (P25036)False negative hits (sequences which belong to the set under consideration, but which have not been picked up by the pattern or profile): ALP2_ASPFC (B0Y473), ALP2_ASPFU (P87184), CUCM1_CUCME (Q39547), HLY_NATA1 (P29143), KEX2_CANAW (O13359), MBTP1_CRIGR (Q9Z2A8), MBTP1_HUMAN (Q14703), MBTP1_MOUSE (Q9WTZ2), MBTP1_RAT (Q9WTZ3), ORYZ_ASPFL (P35211), PCSK5_BRACL (Q9NJ15), PCSK7_HUMAN (Q16549), PCSK7_MOUSE (Q61139), PCSK7_RAT (Q62849), PCSK9_ATEGE (A8T6A1), PCSK9_CALJA (A8T688), PCSK9_CALMO (A8T677), PCSK9_COLGU (A8T672), PCSK9_GORGO (A8T650), PCSK9_HUMAN (Q8NBP7), PCSK9_LAGLA (A8T6A6), PCSK9_MACMU (A8T666), PCSK9_MACNE (A8T662), PCSK9_MOUSE (Q80W65), PCSK9_PANPA (A8T655), PCSK9_PANTR (A8T644), PCSK9_PONPY (A8T658), PCSK9_RAT (P59996), PCSK9_SAGLB (A8T682), PCSK9_SAIBB (A8T695), PEPC_ASPNG (P33295), PRTS_SERMA (P09489), PRTT_SERMA (P29805), SDD1_ARATH (O64495), SPM1_MAGO7 (P58371), SSA1_PASHA (P31631), SU11A_COCP7 (C5P1W9), SU11B_COCP7 (C5PFR5), SUB10_ARTOC (C5FX37), SUB11_ARTBC (D4APE3), SUB11_ARTGP (E4V5C5), SUB11_ARTOC (C5FZ39), SUB11_TRIVH (D4CZ60), SUB12_ARTBC (D4AQA9), SUB12_ARTGP (E4UY04), SUB12_TRIVH (D4D1U5), SUB1_ARTBC (D4AKU9), SUB1_ARTGP (E4UPZ4), SUB1_ARTOC (C5FPS1), SUB1_TRIVH (D4DIW9), SUB2_DEIRA (Q9RYM8), SUB3_ARTBC (D4AWY5), SUB3_ARTGP (E4UN97), SUB3_ARTOC (C5FMY5), SUB3_TRIVH (D4DLA2), SUB4A_COCP7 (C5PCB1), SUB4C_COCP7 (C5P6L5), SUB4_ARTBC (D4AXW3), SUB4_ARTGP (E4UWA4), SUB4_ARTOC (C5FXZ6), SUB4_TRIVH (D4D6Q4), SUB7B_COCP7 (C5PCX1), SUB7_ARTBC (D4APA9), SUB7_ARTGP (E4V2V9), SUB7_ARTOC (C5FJA5), SUB7_TRIVH (D4CZQ4), SUB8_ARTBC (D4AX50), SUB8_ARTOC (C5FII2), SUB8_COCP7 (C5P4Z8), SUB8_TRIVH (D4DKQ4), SUB9_ARTBC (D4B5N1), SUB9_ARTGP (E4UTU7), SUB9_ARTOC (C5FH27), SUB9_COCP7 (C5P5Q3), SUB9_TRIVH (D4D674), SUBF_BACSU (P16397), SUBL_ARATH (O65351), TAGA_DICDI (Q9GTN7), TAGB_DICDI (P54683), TAGC_DICDI (Q23868), TAGD_DICDI (Q8T9W1), TPP2_BOVIN (A5PK39), TPP2_DROME (Q9V6K1), TPP2_HUMAN (P29144), TPP2_MOUSE (Q64514), TPP2_RAT (Q64560), TPP2_SCHPO (Q9UT05), VG47_ICHVA (Q00139), WPRA_BACSU (P54423), YQS6_CAEEL (Q09541)`Potential' hits (partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences): APGR3_BIOOC (P83492), ASE1_ACRSP (P85156), ASE2_ACRSP (P85157), CUDP_METCM (P80406), FIBR2_NEAJA (P86876), NCP3_COPCM (P83454), PRTE_HALME (P28308), SP01_PSEBO (Q10721), THEM_MALSU (P13858)False positive hits (sequences which do not belong to the set under consideration): ACDA1_ARCFU (O29165), AGLU_TETPY (O00906), ALDO3_ARATH (Q7G9P4), AP1_KLULA (P56095), ARGC_CHRVO (Q7NRT5), BAR_RHOER (Q8RSQ2), BTUB_PHOLL (Q7MYE3), CBID_PROMP (Q7V3N8), CLS2_STAAC (Q5HEB2), CLS2_STAAR (Q6GEY7), CLS_STAAM (P63800), CLS_STAAN (P63801), CLS_STAAS (Q6G7M2), CLS_STAAW (P63802), COBT_DEIRA (Q9RYR8), DCL4_ORYSJ (A7LFZ6), DMXL1_HUMAN (Q9Y485), DMXL1_MOUSE (Q6PNC0), DNLJ1_STRGG (B1VUC2), DNLJ_FERNB (A7HJG6), DRD1_CARAU (P35406), EXOC1_DICDI (Q54NV1), FIXJ_AZOC5 (P26487), FLII_BUCBP (Q89AZ7), FMT_GEOSL (Q74GW4), FOLD2_ACIAD (Q6F8N7), FOLD_ACIBT (A3M846), FOLD_MYCPE (Q8EV80), FOLD_PSYA2 (Q4FTX6), FOLD_PSYCK (Q1QD30), FOLD_RUTMC (A1AXA0), FOLD_THETN (Q8RAD0), GLUQ_PROAC (Q6A7Y1), GLYA_MYCS2 (A0R2V7), GLYA_PROAC (Q6AAU3), GUAAB_PICTO (Q6L1Q1), GUAA_ASPOR (Q2UFN0), HEM1_RHORT (Q2RWE2), HIS5_ECOL6 (P60596), HIS5_ECOLI (P60595), HIS5_SHIBS (Q323I9), HIS5_SHIDS (Q32EF2), HIS5_SHIFL (Q83KJ5), HIS5_SHISS (Q3Z0G2), HLYE_ECO57 (Q9REB3), HLYE_ECOLI (P77335), HN1BA_DANRE (A1L1N5), HN1BB_DANRE (Q8UW00), HOA_BURPP (B2T2S2), HOY1_YARLI (Q99160), KATG2_ALKMQ (A6TV07), KATG_PHEZH (B4R8U3), KATG_SACD2 (Q21DT6), KUP3_RHIL3 (Q1M651), LCAP_HUMAN (Q9UIQ6), LEC2_CYTSE (P22971), LEU3_BRUA2 (Q2YL58), LEU3_BRUAB (Q579B1), LEU3_BRUME (Q8YCX4), LEU3_BRUSU (Q8FVF3), LPXK_HELAH (Q17X64), LPXK_HELPH (Q1CUH3), LPXK_HELPJ (Q9ZMB1), LPXK_HELPY (O25095), LRC14_BOVIN (A5PJJ5), LRC14_HUMAN (Q15048), LRC14_MOUSE (Q8VC16), LRC14_RAT (Q569B5), LRRC3_DANRE (A8WHP9), MATK_GAGLU (Q9TMC8), MATK_ILLOL (A6MMS5), METL2_ARATH (Q8LFA9), METN1_PSEU2 (Q4ZZR8), MSTO1_BOVIN (A5D9D4), MSTO1_HUMAN (Q9BUK6), MSTO1_MACFA (Q4R681), MSTO1_MOUSE (Q2YDW2), MSTO1_PONPY (Q5RF82), MYO2_CAEEL (P12845), MZT1B_ARATH (Q9M0N8), NADE_SHEON (Q8EFF2), NADO2_ORYSJ (Q7G765), NCAP_CVM1 (P18446), NCAP_CVM2 (Q9PY96), NCAP_CVM3 (P18447), NCAP_CVMA5 (P03416), NCAP_CVMDV (Q83360), NCAP_CVMJH (P03417), NCAP_CVMS (P18448), NCAP_CVPV (P59713), NCAP_CVRNJ (Q9WCD0), NCAP_CVRSD (Q02915), NEMS_APIME (P85527), NOL6_DROME (Q8IH00), NOL6_DROSE (B4IBY3), NOL6_DROSI (B4QX57), NOL6_DROYA (B4PR18), NR2C1_BOVIN (A0JNE3), NR2C1_HUMAN (P13056), NR2C1_MACFA (Q95K90), NR2C1_MOUSE (Q505F1), NR2C1_PONAB (Q5RCZ5), NR2C1_RAT (Q8VIJ4), NR2C1_XENTR (Q28CK1), NUS1_ASPOR (P24021), PA24A_BOVIN (A4IFJ5), PA24A_CHICK (P49147), PA24A_DANRE (P50392), PA24A_HORSE (O77793), PA24A_HUMAN (P47712), PA24A_MOUSE (P47713), PA24A_PONAB (Q5R8A5), PA24A_RABIT (Q9TT38), PA24A_RAT (P50393), PA24A_XENLA (Q7T0T9), PA24A_XENTR (B1WAZ6), PDAD_METKA (Q8TXD4), PEPQ_AERHH (A0KEL3), PEPQ_AERS4 (A4STF0), PGP_ARCFU (O29805), PNP_FRAT1 (Q14IC9), PNP_FRATF (A7NDP3), PNP_FRATH (Q2A269), PNP_FRATM (B2SDK7), PNP_FRATN (A0Q5I9), PNP_FRATO (Q0BKU1), PNP_FRATT (Q5NGX7), PNP_FRATW (A4IZA6), PP263_ARATH (Q9M2A1), PPOC_ARATH (P55826), PRIM_NEIMA (P57028), PRIM_NEIMB (P57029), PURA_LEIDO (A7LBL2), PURA_LEIIN (A4HVP7), PURA_LEIMA (Q4QG35), PYRE_PHOLL (Q7MY25), PYRE_SHEON (Q8E9L5), PYRE_VIBCH (Q9KVD5), RNJ1_STAA3 (Q2FHZ1), RNJ1_STAA8 (Q2FZG9), RNJ1_STAAB (Q2YX35), RNJ1_STAAC (Q5HGZ5), RNJ1_STAAM (Q99V09), RNJ1_STAAN (Q7A682), RNJ1_STAAR (Q6GHZ6), RNJ1_STAAS (Q6GAC5), RNJ1_STAAW (Q7A171), RNJ1_STAEQ (Q5HQ80), RNJ1_STAES (Q8CT16), RNJ1_STAHJ (Q4L5A3), RNJ1_STAS1 (Q49WL3), RPOB_KORVE (Q1IHH4), RR2_THAPS (A0T0Q8), SC6_SCHCO (O74300), SECA_MYCPU (Q98RA6), SEY1_SCHPO (Q9UTE0), SMI1_SCHPO (O14362), STE13_YEAST (P33894), SYFB_THIDA (Q3SK29), T2S1_LACLC (O34104), TEN1_HUMAN (Q9UKZ4), TEN1_MOUSE (Q9WTS4), TRP3_ARATH (Q9C7B1), VL2_HPV42 (P27235), XERS_LACLA (Q9CG78), XERS_LACLM (A2RKP9), XERS_LACLS (Q02YZ4), XOL1_CAEEL (Q23229), Y072_CHLTR (O84075), Y1273_MYCTU (P0A4W4), Y1304_MYCBO (P0A4W5), Y1776_COREF (Q8FPK2), Y344_CHLMU (Q9PKW7), Y4KK_RHISN (P55529), Y5194_MYCGI (A4T1E2), Y973_METJA (Q58383), YFIB_BACSU (P54718), YQ02_CAEEL (Q17405), YSH1_ASHGO (Q74ZC0), YSH1_YARLI (Q6C2Z7)Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits: [Clustal format, color, condensed view]
[Clustal format, color]
[Clustal format, plain text]
[Fasta format]
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| PDB [Detailed view] |
1A2Q; 1AF4; 1AH2; 1AK9; 1AQN; 1AU9; 1AV7; 1AVT; 1BE6; 1BE8; 1BFK; 1BFU; 1BH6; 1BJR; 1C3L; 1C9J; 1C9M; 1C9N; 1CNM; 1CSE; 1DBI; 1DUI; 1EGQ; 1GCI; 1GNS; 1GNV; 1HT3; 1IAV; 1IC6; 1JEA; 1LW6; 1MEE; 1MPT; 1NDQ; 1NDU; 1OT5; 1OYO; 1OYV; 1P7V; 1P7W; 1P8J; 1PEK; 1PFG; 1PJ8; 1PTK; 1Q5P; 1R0R; 1R64; 1S01; 1S02; 1SBC; 1SBH; 1SBI; 1SBN; 1SBT; 1SCA; 1SCB; 1SCD; 1SCJ; 1SCN; 1SEL; 1SIB; 1ST2; 1ST3; 1SUA; 1SUB; 1SUC; 1SUD; 1SUE; 1SUP; 1SVN; 1TEC; 1THM; 1TK2; 1TM1; 1TM3; 1TM4; 1TM5; 1TM7; 1TMG; 1TO1; 1TO2; 1UBN; 1V5I; 1VSB; 1WSD; 1XF1; 1Y1K; 1Y33; 1Y34; 1Y3B; 1Y3C; 1Y3D; 1Y3F; 1Y48; 1Y4A; 1Y4D; 1YJA; 1YJB; 1YJC; 1YU6; 2DP4; 2DQK; 2DUJ; 2E1P; 2G4V; 2HD4; 2HPZ; 2ID4; 2ID8; 2PKC; 2PQ2; 2PRK; 2PWA; 2PWB; 2PYZ; 2SBT; 2SEC; 2SIC; 2SNI; 2ST1; 2TEC; 2V8B; 2WUV; 2WUW; 2Z2X; 2Z2Y; 2Z2Z; 2Z30; 2Z56; 2Z57; 2Z58; 2ZRQ; 2ZWO; 2ZWP; 3A3N; 3A3O; 3A3P; 3AJ8; 3AJ9; 3BX1; 3D9Q; 3DDZ; 3DE0; 3DE1; 3DE2; 3DE3; 3DE4; 3DE5; 3DE6; 3DE7; 3DVQ; 3DVR; 3DVS; 3DW1; 3DW3; 3DWE; 3DYB; 3EIF; 3F7M; 3GT3; 3GT4; 3I2Y; 3I30; 3I34; 3I37; 3L1K; 3OSZ; 3PRK; 3PTL; 3Q40; 3Q5G; 3QMP; 3SIC; 3TEC; 3UNX; 3VHQ; 3VSB; 3VV2; 4B5L; 4DJ5; 4DWW; 4DZT; 4FON; 5SIC; |
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