Entry: PS00143

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General information about the entry

Entry name [info] INSULINASE
Accession [info] PS00143
Entry type [info] PATTERN
Date [info] APR-1990 (CREATED); NOV-1997 (DATA UPDATE); MAR-2014 (INFO UPDATE).
PROSITE Doc. [info] PDOC00130
Associated ProRule [info] PRU10096

Name and characterization of the entry

Description [info] Insulinase family, zinc-binding region signature.
Pattern [info]
G-x(8,9)-G-x-[STA]-H-[LIVMFY]-[LIVMC]-[DERN]-[HRKL]-[LMFAT]-x-[LFSTH]-x-
[GSTAN]-[GST].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2014_04 which contains 544'996 sequence entries.


Total number of hits 70 in 70 different sequences
Number of true positive hits 70 in 70 different sequences
Number of 'unknown' hits
Number of false positive hits
Number of false negative sequences 36
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 66.04 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] zinc at position 6
Site [info] active_site at position 9
Site [info] zinc at position 10
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
70 sequences

AXL1_YEAST  (P40851), IDE_BOVIN   (Q24K02), IDE_DICDI   (Q54JQ2), 
IDE_DROME   (P22817), IDE_HUMAN   (P14735), IDE_MOUSE   (Q9JHR7), 
IDE_RAT     (P35559), MPPA1_ARATH (Q9ZU25), MPPA2_ARATH (O04308), 
MPPA_BOVIN  (Q0P5M8), MPPA_HUMAN  (Q10713), MPPA_MOUSE  (Q9DC61), 
MPPA_NEUCR  (P23955), MPPA_PONAB  (Q5R513), MPPA_RAT    (P20069), 
MPPA_SCHPO  (O94745), MPPA_SOLTU  (P29677), MPPA_YEAST  (P11914), 
MPPB_ARATH  (Q42290), MPPB_BOVIN  (Q3SZ71), MPPB_DICDI  (Q4W6B5), 
MPPB_HUMAN  (O75439), MPPB_LENED  (Q9Y8B5), MPPB_MOUSE  (Q9CXT8), 
MPPB_NEUCR  (P11913), MPPB_PONAB  (Q5REK3), MPPB_RAT    (Q03346), 
MPPB_SCHPO  (Q9P7X1), MPPB_YEAST  (P10507), MU138_SCHPO (O14077), 
NRDC_HUMAN  (O43847), NRDC_MOUSE  (Q8BHG1), NRDC_PONAB  (Q5R4H6), 
NRDC_RAT    (P47245), PQQF_KLEPN  (P27508), PQQF_PSEAE  (Q9I2D2), 
PQQF_PSEFL  (P55174), PQQF_PSEPK  (Q88QV3), PQQF_PSESM  (Q88A79), 
PQQL_ECOLI  (P31828), PQQL_HAEIN  (P45181), PTRA_ECO57  (Q8X6M8), 
PTRA_ECOL6  (Q8CVS2), PTRA_ECOLI  (P05458), PTRA_SALTY  (Q8ZMB5), 
PTRA_SHIFL  (Q83QC3), PXM16_ARATH (O22941), QCR1_EUGGR  (P43264), 
QCR2_BOVIN  (P23004), QCR2_HUMAN  (P22695), QCR2_MOUSE  (Q9DB77), 
QCR2_RAT    (P32551), QCR2_YARLI  (Q6C2E3), QCR2_YEAST  (P07257), 
SDP_EIMBO   (P42789), STE23_YEAST (Q06010), UCR1_CAEEL  (P98080), 
Y210_RICTY  (Q68XF0), Y219_RICPR  (O05945), Y2782_MYCTO (P9WHT4), 
Y2782_MYCTU (P9WHT5), Y2805_MYCBO (P0A5S9), Y293_RICCN  (Q92IX7), 
Y338_RICFE  (Q4UML9), Y4WA_RHISN  (P55679), Y522_RICBR  (Q1RJ61), 
Y5738_STRCO (O86835), Y855_MYCLE  (O32965), YMXG_BACSU  (Q04805), 
YQA4_CAEEL  (Q10040)
» More

UniProtKB/Swiss-Prot
False negative sequences
36 sequences

ALBF_BACIU  (Q8RKH2), ALBF_BACSU  (P71006), CYM1_ASHGO  (Q759T9), 
CYM1_ASPFU  (Q4WP38), CYM1_ASPOR  (Q2UGN1), CYM1_CANAL  (Q5A301), 
CYM1_CANGA  (Q6FUI7), CYM1_DEBHA  (Q6BTC0), CYM1_EMENI  (Q5B6H7), 
CYM1_GIBZE  (Q4IA56), CYM1_KLULA  (Q6CWW6), CYM1_NEUCR  (Q7S7C0), 
CYM1_SCHPO  (O42908), CYM1_YARLI  (Q6C0U8), CYM1_YEAST  (P32898), 
MPPA_BLAEM  (P97997), PREP1_ARATH (Q9LJL3), PREP2_ARATH (Q8VY06), 
PREP_DANRE  (Q7ZVZ6), PREP_DROME  (Q9V9E3), PREP_HUMAN  (Q5JRX3), 
PREP_MOUSE  (Q8K411), PREP_PONAB  (Q5RDG3), PREP_XENLA  (Q6PF24), 
PREP_XENTR  (Q28BR5), PTRA_SALTI  (Q8Z418), QCR1_BOVIN  (P31800), 
QCR1_HUMAN  (P31930), QCR1_MOUSE  (Q9CZ13), QCR1_YEAST  (P07256), 
QCR2_EUGGR  (P43265), Y4WB_RHISN  (P55680), YHJJ_ECOLI  (P37648), 
YHJJ_SALTI  (Q8Z286), YHJJ_SALTY  (P50335), YMFH_BACSU  (O31766)
» More

PDB
[Detailed view]
41 PDB

1BCC; 1BE3; 1BGY; 1EZV; 1HR6; 1HR7; 1HR8; 1HR9; 1KB9; 1KYO; 1L0L; 1L0N; 1NTK; 1NTM; 1NTZ; 1NU1; 1P84; 1PP9; 1PPJ; 1Q2L; 1QCR; 1SQB; 1SQP; 1SQQ; 1SQV; 1SQX; 2A06; 2BCC; 2FYU; 2IBZ; 2JG4; 2YBB; 3BCC; 3CX5; 3CXH; 3P7L; 3QZ2; 3TUV; 4DTT; 4IFH; 4IOF
» More

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