Entry: PS00161

General information about the entry
Entry name ISOCITRATE_LYASE
Accession number PS00161
Entry type PATTERN
Date APR-1990 (CREATED); DEC-2001 (DATA UPDATE); MAR-2013 (INFO UPDATE).
PROSITE Documentation PDOC00145
Associated ProRule PRU10119
Name and characterization of the entry
DescriptionIsocitrate lyase signature.
Pattern K-[KR]-C-G-H-[LMQR].
Numerical results
  • UniProtKB/Swiss-Prot release number: 2013_05, total number of sequence entries in that release: 540052.
  • Total number of hits in UniProtKB/Swiss-Prot: 57 hits in 57 different sequences
  • Number of hits on proteins that are known to belong to the set under consideration: 55 hits in 55 different sequences
  • Number of hits on proteins that could potentially belong to the set under consideration: 0 hits in 0 different sequences
  • Number of false hits (on unrelated proteins): 2 hits in 2 different sequences
  • Number of known missed hits: 7
  • Number of partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences: 2
  • Precision (true hits / (true hits + false positives)): 96.49 %
  • Recall (true hits / (true hits + false negatives)): 88.71 %
Comments
  • Taxonomic range: Archaea, Eukaryotes, Prokaryotes (Bacteria)
  • Maximum known number of repetitions of the pattern in a single protein: 1
  • `Interesting' site in the pattern: 3,active_site(?)
  • VERSION: 1
Cross-references
UniProtKB/Swiss-Prot True positive hits:
ACEA1_SOYBN (P45456), ACEA2_SOYBN (P45457), ACEA_ARATH  (P28297), 
ACEA_ASHGO  (O94198), ACEA_ASPFU  (Q6T267), ACEA_BACHD  (Q9K9H0), 
ACEA_BRANA  (P25248), ACEA_CANAX  (Q9P8Q7), ACEA_CANGA  (Q6FPK7), 
ACEA_CANTR  (P20014), ACEA_COCIM  (Q96TP5), ACEA_COPC7  (A8NR45), 
ACEA_COPCI  (O13439), ACEA_COREF  (Q8RQN6), ACEA_CORGL  (P42449), 
ACEA_CUCMA  (P93110), ACEA_CUCSA  (P49296), ACEA_CYBJA  (Q9HFN2), 
ACEA_DEBHA  (Q6BRY4), ACEA_DENCR  (Q9SE26), ACEA_ECOL6  (P0A9G7), 
ACEA_ECOLI  (P0A9G6), ACEA_EMENI  (P28298), ACEA_GIBZE  (Q4HYR2), 
ACEA_GOSHI  (P17069), ACEA_KLULA  (Q8NJ72), ACEA_LEPMC  (Q86ZF1), 
ACEA_MAGO7  (Q8J232), ACEA_MYCBO  (P0A5H4), ACEA_MYCLE  (P46831), 
ACEA_MYCTU  (P0A5H3), ACEA_NEUCR  (P28299), ACEA_PENMA  (Q96WZ5), 
ACEA_PICPA  (Q9C124), ACEA_PINTA  (Q43097), ACEA_RHOFA  (P41554), 
ACEA_RICCO  (P15479), ACEA_SALTY  (P51066), ACEA_SOLLC  (P49297), 
ACEA_YARLI  (P41555), ACEA_YEAST  (P28240), ACEB_YEAST  (Q12031), 
CPPM_ARATH  (O49290), CPPM_STRHY  (P11435), DML_EUBBA   (Q0QLE4), 
GCP_CAEEL   (Q10663), PDP_DIACA   (Q05957), PRPB1_CORGL (Q8NSH8), 
PRPB2_CORGL (Q8NSL2), PRPB_AERPE  (Q9YFM7), PRPB_BACHD  (Q9Z9T7), 
PRPB_BACSU  (P54528), PRPB_ECOLI  (P77541), PRPB_SALTY  (Q56062), 
PRPB_VIBCH  (Q9KSC2)
False negative hits (sequences which belong to the set under consideration, but which have not been picked up by the pattern or profile):
ACEA_PSEAE  (Q9I0K4), ACEB_SCHPO  (Q9P6J1), PEPM_MYTED  (P56839), 
PEPM_STRHY  (P29247), PEPM_STRVR  (O86937), PEPM_TETPY  (P33182), 
PPHA_VARSP  (Q84G06)
`Potential' hits (partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences):
ACEA_ACICA  (P28467), ACEA_HELAN  (P20699)
False positive hits (sequences which do not belong to the set under consideration):
KLKB1_BOVIN (Q2KJ63), SYL_ANAMM   (Q5PB38)
Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:

[Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format]

Retrieve the sequence logo from the alignment

PDB
[Detailed view]		 1F61; 1F8M; 1IGW; 1MUM; 1MZX; 1OQF; 1ZLP;

View entry in original PROSITE format
View entry in raw text format (no links)
Direct ScanProsite submission

If you would like to retrieve all the Swiss-Prot entries referenced in the DR lines of this entry (with the exception of false positive hits) , you can enter a file name. These entries will then be saved to a file under this name. (Please note that this temporary file will only be kept for 1 week.)

File name:

Format: Swiss-Prot Fasta

or