Entry: PS00161

General information about the entry

Entry name [info] ISOCITRATE_LYASE
Accession [info] PS00161
Entry type [info] PATTERN
Date [info] APR-1990 (CREATED); DEC-2001 (DATA UPDATE); MAY-2016 (INFO UPDATE).
PROSITE Doc. [info] PDOC00145
Associated ProRule [info] PRU10119

Name and characterization of the entry

Description [info] Isocitrate lyase signature.
Pattern [info]
K-[KR]-C-G-H-[LMQR].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2016_05 which contains 551'193 sequence entries.


Total number of hits 70 in 70 different sequences
Number of true positive hits 68 in 68 different sequences
Number of 'unknown' hits 0
Number of false positive hits 2 in 2 different sequences
Number of false negative sequences 7
Number of 'partial' sequences 2
Precision (true positives / (true positives + false positives)) 97.14 %
Recall (true positives / (true positives + false negatives)) 90.67 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] active_site(?) at position 3
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
68 sequences

ACEA1_MYCBO (P0A5H4    ), ACEA1_MYCTE (H8EVV4    ), ACEA1_MYCTO (P9WKK6    ), 
ACEA1_SOYBN (P45456    ), ACEA2_MYCBO (Q7TZA8    ), ACEA2_MYCTE (H8F3R6    ), 
ACEA2_MYCTO (Q8VJU4    ), ACEA2_SOYBN (P45457    ), ACEAA_MYCTU (O07718    ), 
ACEA_ARATH  (P28297    ), ACEA_ASHGO  (O94198    ), ACEA_ASPFU  (Q6T267    ), 
ACEA_BACHD  (Q9K9H0    ), ACEA_BRANA  (P25248    ), ACEA_CANAX  (Q9P8Q7    ), 
ACEA_CANGA  (Q6FPK7    ), ACEA_CANTR  (P20014    ), ACEA_COCIM  (Q96TP5    ), 
ACEA_COPC7  (A8NR45    ), ACEA_COPCI  (O13439    ), ACEA_COREF  (Q8RQN6    ), 
ACEA_CORGL  (P42449    ), ACEA_CUCMA  (P93110    ), ACEA_CUCSA  (P49296    ), 
ACEA_CYBJA  (Q9HFN2    ), ACEA_DEBHA  (Q6BRY4    ), ACEA_DENCR  (Q9SE26    ), 
ACEA_ECOL6  (P0A9G7    ), ACEA_ECOLI  (P0A9G6    ), ACEA_EMENI  (P28298    ), 
ACEA_GIBZE  (Q4HYR2    ), ACEA_GOSHI  (P17069    ), ACEA_KLULA  (Q8NJ72    ), 
ACEA_LEPMC  (Q86ZF1    ), ACEA_MAGO7  (P0CT06    ), ACEA_MAGOY  (L7HUY5    ), 
ACEA_MYCLE  (P46831    ), ACEA_MYCTU  (P9WKK7    ), ACEA_NEUCR  (P28299    ), 
ACEA_ORYSJ  (Q6Z6M4    ), ACEA_PICPA  (Q9C124    ), ACEA_PINTA  (Q43097    ), 
ACEA_RHOFA  (P41554    ), ACEA_RICCO  (P15479    ), ACEA_SALTY  (P51066    ), 
ACEA_SOLLC  (P49297    ), ACEA_TALMA  (Q96WZ5    ), ACEA_YARLI  (P41555    ), 
ACEA_YEAST  (P28240    ), ACEB_EMENI  (C8V9Y5    ), ACEB_HYPAI  (G9NNY7    ), 
ACEB_YARLI  (Q6BZP5    ), ACEB_YEAST  (Q12031    ), CPPM_ARATH  (O49290    ), 
CPPM_STRHY  (P11435    ), DML_EUBBA   (Q0QLE4    ), GCP_CAEEL   (Q10663    ), 
PDP_DIACA   (Q05957    ), PRPB1_CORGL (Q8NSH8    ), PRPB2_CORGL (Q8NSL2    ), 
PRPB_AERPE  (Q9YFM7    ), PRPB_BACHD  (Q9Z9T7    ), PRPB_BACSU  (P54528    ), 
PRPB_CUPNE  (Q937P0    ), PRPB_ECOLI  (P77541    ), PRPB_SALTY  (Q56062    ), 
PRPB_SHEON  (Q8EJW1    ), PRPB_VIBCH  (Q9KSC2    )
» more

UniProtKB/Swiss-Prot
False negative sequences
7 sequences

ACEA_PSEAE  (Q9I0K4    ), ACEB_SCHPO  (Q9P6J1    ), PEPM_MYTED  (P56839    ), 
PEPM_STRHY  (P29247    ), PEPM_STRVT  (O86937    ), PEPM_TETPY  (P33182    ), 
PPHA_VARSP  (Q84G06    )
» more

UniProtKB/Swiss-Prot
'Partial' sequences
2 sequences

ACEA_ACICA  (P28467    ), ACEA_HELAN  (P20699    )

		
UniProtKB/Swiss-Prot
False positive sequences
2 sequences

KLKB1_BOVIN (Q2KJ63    ), SYL_ANAMM   (Q5PB38    )

		
PDB
[Detailed view]
6 PDB

1F61; 1F8M; 1IGW; 1MUM; 1OQF; 1ZLP

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