To improve security and privacy, we are moving our web pages and services from HTTP to HTTPS.
To give users of web services time to transition to HTTPS, we will support separate HTTP and HTTPS services until the end of 2017.
From January 2018 most HTTP traffic will be automatically redirected to HTTPS. [more...]
View this page in https
Entry: PS00183

General information about the entry

Entry name [info] UBIQUITIN_CONJUGAT_1
Accession [info] PS00183
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED; 01-APR-2006 DATA UPDATE; 22-NOV-2017 INFO UPDATE.
PROSITE Doc. [info] PDOC00163
Associated ProRule [info] PRU10133

Name and characterization of the entry

Description [info] Ubiquitin-conjugating enzymes active site.
Pattern [info]
[FYWLSP]-H-[PC]-[NHL]-[LIV]-x(3,4)-G-x-[LIVP]-C-[LIV]-x(1,2)-[LIVR].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2017_11 which contains 556'196 sequence entries.


Total number of hits 239 in 239 different sequences
Number of true positive hits 239 in 239 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 89
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 72.87 %

Comments [info]

Taxonomic range [info] Eukaryotes, Eukaryotic viruses
Maximum number of repetitions [info] 1
Site [info] active_site at position 10
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
239 sequences

PEX4_ARATH  (Q8LGF7    ), RCE1_ARATH  (Q9SDY5    ), SCE1_ARATH  (Q42551    ), 
U2D2B_MOUSE (Q6ZWY6    ), U2D2B_RAT   (P70711    ), UB12L_ARATH (Q9ZU75    ), 
UB2D1_BOVIN (Q2TA10    ), UB2D1_HUMAN (P51668    ), UB2D1_MOUSE (P61080    ), 
UB2D1_RAT   (D3ZDK2    ), UB2D2_BOVIN (Q1RMX2    ), UB2D2_HUMAN (P62837    ), 
UB2D2_MOUSE (P62838    ), UB2D2_PIG   (Q06AA9    ), UB2D2_RAT   (P62839    ), 
UB2D2_XENLA (P62840    ), UB2D3_HUMAN (P61077    ), UB2D3_MACFA (Q4R5N4    ), 
UB2D3_MOUSE (P61079    ), UB2D3_PONAB (Q5R4V7    ), UB2D3_RAT   (P61078    ), 
UB2D4_HUMAN (Q9Y2X8    ), UB2D4_XENLA (A5PKP9    ), UB2E1_HUMAN (P51965    ), 
UB2E1_MOUSE (P52482    ), UB2E2_HUMAN (Q96LR5    ), UB2E2_MOUSE (Q91W82    ), 
UB2E3_BOVIN (Q2T9X7    ), UB2E3_HUMAN (Q969T4    ), UB2E3_MOUSE (P52483    ), 
UB2FA_MOUSE (Q9CY34    ), UB2FB_MOUSE (Q3UWQ3    ), UB2G1_HUMAN (P62253    ), 
UB2G1_MACFA (Q4R5Y8    ), UB2G1_MOUSE (P62254    ), UB2G1_RAT   (P62255    ), 
UB2G2_BOVIN (Q17QG5    ), UB2G2_HUMAN (P60604    ), UB2G2_MOUSE (P60605    ), 
UB2G2_PONAB (Q5RF84    ), UB2L3_BOVIN (Q3MHP1    ), UB2L3_HUMAN (P68036    ), 
UB2L3_MOUSE (P68037    ), UB2L3_PONAB (Q5R5I4    ), UB2L6_BOVIN (A5PJC4    ), 
UB2L6_HUMAN (O14933    ), UB2L6_MOUSE (Q9QZU9    ), UB2L6_RAT   (Q4V8J2    ), 
UB2R1_HUMAN (P49427    ), UB2R1_MOUSE (Q8CFI2    ), UB2R2_HUMAN (Q712K3    ), 
UB2R2_MOUSE (Q6ZWZ2    ), UB2R2_RABIT (Q29503    ), UB2SA_XENLA (A1L3K1    ), 
UB2SB_XENLA (Q8AVU2    ), UB2SC_XENLA (Q76EZ2    ), UBC10_ARATH (P35133    ), 
UBC11_ARATH (P35134    ), UBC11_SCHPO (O00103    ), UBC11_YEAST (P52492    ), 
UBC12_ARATH (Q9C9Y7    ), UBC12_ASHGO (Q75AF2    ), UBC12_BOVIN (A3KN22    ), 
UBC12_CAEEL (Q9XVK5    ), UBC12_CANGA (Q6FVQ8    ), UBC12_DICDI (Q54TI6    ), 
UBC12_DROME (Q9VSF3    ), UBC12_HUMAN (P61081    ), UBC12_KLULA (Q6CSW8    ), 
UBC12_MOUSE (P61082    ), UBC12_SCHPO (O74549    ), UBC12_XENLA (Q6DCZ9    ), 
UBC12_XENTR (Q6P8D9    ), UBC12_YARLI (Q6C9W0    ), UBC12_YEAST (P52491    ), 
UBC13_ARATH (Q42541    ), UBC13_CAEEL (Q95XX0    ), UBC13_SCHPO (O13685    ), 
UBC13_YEAST (P52490    ), UBC14_ARATH (P42747    ), UBC15_ARATH (P42743    ), 
UBC15_SCHPO (Q9Y818    ), UBC16_ARATH (Q9FWT2    ), UBC17_ARATH (O23239    ), 
UBC18_ARATH (Q9FMM0    ), UBC19_ARATH (Q9LJZ5    ), UBC1_ARATH  (P25865    ), 
UBC1_CAEEL  (P52478    ), UBC1_COLGL  (O74196    ), UBC1_MAGO7  (Q9UVR2    ), 
UBC1_SCHPO  (O74810    ), UBC1_YEAST  (P21734    ), UBC20_ARATH (Q8L7T3    ), 
UBC21_CAEEL (P52484    ), UBC22_ARATH (Q9FF66    ), UBC27_ARATH (Q9FI61    ), 
UBC28_ARATH (Q94F47    ), UBC29_ARATH (Q9SLE4    ), UBC2_ARATH  (P42745    ), 
UBC2_ASHGO  (Q75EB8    ), UBC2_ASPFU  (Q4WLA7    ), UBC2_CAEEL  (P35129    ), 
UBC2_CANAL  (O74201    ), UBC2_CANGA  (Q6FR76    ), UBC2_CRYNB  (P0CS17    ), 
UBC2_CRYNJ  (P0CS16    ), UBC2_DEBHA  (Q6BU36    ), UBC2_DICDI  (Q553F3    ), 
UBC2_EMENI  (Q96UP5    ), UBC2_KLULA  (Q6CUD9    ), UBC2_MEDSA  (P35130    ), 
UBC2_NECHA  (P78717    ), UBC2_NEUCR  (P52493    ), UBC2_SCHPO  (P23566    ), 
UBC2_TRIHA  (Q58FS2    ), UBC2_USTMA  (Q4PFA5    ), UBC2_WHEAT  (P25866    ), 
UBC2_YARLI  (Q6C093    ), UBC2_YEAST  (P06104    ), UBC30_ARATH (Q9FKT3    ), 
UBC35_ARATH (Q94A97    ), UBC36_ARATH (Q9FZ48    ), UBC37_ARATH (Q941B6    ), 
UBC3_ARATH  (P42746    ), UBC3_YEAST  (P14682    ), UBC4_ARATH  (P42748    ), 
UBC4_CANAX  (P43102    ), UBC4_SCHPO  (P46595    ), UBC4_SOLLC  (P35135    ), 
UBC4_WHEAT  (P16577    ), UBC4_YEAST  (P15731    ), UBC5A_ORYSJ (Q8S920    ), 
UBC5B_ORYSJ (Q8S919    ), UBC5_ARATH  (P42749    ), UBC5_YEAST  (P15732    ), 
UBC6_ARATH  (P42750    ), UBC7_ARATH  (Q42540    ), UBC7_CAEEL  (P34477    ), 
UBC7_SCHPO  (O00102    ), UBC7_WHEAT  (P25868    ), UBC7_YEAST  (Q02159    ), 
UBC84_DROME (P52487    ), UBC8_ARATH  (P35131    ), UBC8_SCHPO  (Q9P7R4    ), 
UBC8_YEAST  (P28263    ), UBC9A_DANRE (Q9W6H5    ), UBC9B_DANRE (Q9DDJ0    ), 
UBC9_ARATH  (P35132    ), UBC9_CAEEL  (Q95017    ), UBC9_CHICK  (P63283    ), 
UBC9_DICDI  (Q9NGP4    ), UBC9_HUMAN  (P63279    ), UBC9_ICTTR  (Q2EF73    ), 
UBC9_MESAU  (O09181    ), UBC9_MOUSE  (P63280    ), UBC9_PAGMA  (Q6Y1Z4    ), 
UBC9_RAT    (P63281    ), UBC9_SCHPO  (P40984    ), UBC9_XENLA  (P63282    ), 
UBC9_XENTR  (Q28CQ4    ), UBC9_YEAST  (P50623    ), UBCD1_DROME (P25867    ), 
UBCD2_DROME (P52485    ), UBCD4_DROME (P52486    ), UBCD6_DROME (P25153    ), 
UBCX_DICDI  (Q86IZ3    ), UBCX_PICAN  (O60015    ), UBCX_PICPA  (P49428    ), 
UBCX_YEAST  (P29340    ), UBC_ASFB7   (P27949    ), UBC_ASFK5   (P0C8G3    ), 
UBC_ASFM2   (P25869    ), UBC_ASFP4   (P0C8G4    ), UBC_ASFWA   (P0C8G5    ), 
UBE2A_HUMAN (P49459    ), UBE2A_MOUSE (Q9Z255    ), UBE2B_BOVIN (Q32P99    ), 
UBE2B_HUMAN (P63146    ), UBE2B_MOUSE (P63147    ), UBE2B_RABIT (P63148    ), 
UBE2B_RAT   (P63149    ), UBE2C_BOVIN (Q32PA5    ), UBE2C_DICDI (Q54XS6    ), 
UBE2C_DROME (Q9VTY6    ), UBE2C_HUMAN (O00762    ), UBE2C_MACFA (Q4R9D1    ), 
UBE2C_MOUSE (Q9D1C1    ), UBE2C_SPISO (Q95044    ), UBE2C_XENLA (P56616    ), 
UBE2F_BOVIN (Q1RMW1    ), UBE2F_CHICK (Q5ZKX6    ), UBE2F_DANRE (Q6NY82    ), 
UBE2F_HUMAN (Q969M7    ), UBE2F_RAT   (Q5U203    ), UBE2F_XENLA (Q6IRC7    ), 
UBE2F_XENTR (Q5M8Y2    ), UBE2H_BOVIN (Q32LN1    ), UBE2H_HUMAN (P62256    ), 
UBE2H_MOUSE (P62257    ), UBE2K_BOVIN (P61085    ), UBE2K_HUMAN (P61086    ), 
UBE2K_MOUSE (P61087    ), UBE2N_BOVIN (Q0P5K3    ), UBE2N_DICDI (Q86K32    ), 
UBE2N_DROME (P35128    ), UBE2N_HUMAN (P61088    ), UBE2N_MACFA (Q4R4I1    ), 
UBE2N_MOUSE (P61089    ), UBE2N_PONAB (Q5R7J6    ), UBE2N_RAT   (Q9EQX9    ), 
UBE2S_BOVIN (Q1RML1    ), UBE2S_BRAFL (C3Z724    ), UBE2S_DANRE (Q4V908    ), 
UBE2S_DICDI (Q54I43    ), UBE2S_DROAN (B3MQV3    ), UBE2S_DROER (B3NWW9    ), 
UBE2S_DROGR (B4JKB7    ), UBE2S_DROME (Q9VX25    ), UBE2S_DROMO (B4L7V4    ), 
UBE2S_DROPE (B4H9W2    ), UBE2S_DROPS (B5DKM4    ), UBE2S_DROSE (B4IF39    ), 
UBE2S_DROSI (B4R6G1    ), UBE2S_DROVI (B4MA02    ), UBE2S_DROWI (B4N208    ), 
UBE2S_DROYA (B4Q2J2    ), UBE2S_HUMAN (Q16763    ), UBE2S_LITCT (C1C3R6    ), 
UBE2S_MOUSE (Q921J4    ), UBE2S_NEMVE (A7SE05    ), UBE2S_RAT   (B5DFI8    ), 
UBE2S_XENTR (Q28F89    ), UBE2T_BOVIN (Q32LD2    ), UBE2T_DANRE (Q08BH7    ), 
UBE2T_HUMAN (Q9NPD8    ), UBE2T_MOUSE (Q9CQ37    ), UBE2T_XENLA (Q7ZY08    ), 
UBE2U_HUMAN (Q5VVX9    ), UBE2U_MACFA (Q95LM1    )
» more

UniProtKB/Swiss-Prot
False negative sequences
89 sequences

BIRC6_HUMAN (Q9NR09    ), BIRC6_MOUSE (O88738    ), COP10_ARATH (Q9LJD7    ), 
ELCL_ARATH  (Q9FFY6    ), ELC_ARATH   (Q9LHG8    ), MMS2_SCHPO  (O74983    ), 
MMS2_YEAST  (P53152    ), SST6_SCHPO  (Q7Z992    ), STP22_YEAST (P25604    ), 
TS101_HUMAN (Q99816    ), TS101_MOUSE (Q61187    ), U2D2L_HUMAN (Q8IWF7    ), 
U2QL1_DROME (Q9VM35    ), U2QL1_HUMAN (A1L167    ), U2QL1_MOUSE (A0PJN4    ), 
UB2J1_HUMAN (Q9Y385    ), UB2J1_MOUSE (Q9JJZ4    ), UB2J2_BOVIN (Q2TA03    ), 
UB2J2_DICDI (Q54LP7    ), UB2J2_HUMAN (Q8N2K1    ), UB2J2_MOUSE (Q6P073    ), 
UB2JL_DICDI (Q54AK6    ), UB2Q1_HUMAN (Q7Z7E8    ), UB2Q1_MOUSE (Q7TSS2    ), 
UB2Q2_BOVIN (Q32L27    ), UB2Q2_HUMAN (Q8WVN8    ), UB2Q2_MOUSE (Q8K2Z8    ), 
UB2Q2_RABIT (Q7YQJ9    ), UB2V1_BOVIN (Q3SZ52    ), UB2V1_CHICK (Q90879    ), 
UB2V1_HUMAN (Q13404    ), UB2V1_MOUSE (Q9CZY3    ), UB2V1_PONAB (Q5R4Z6    ), 
UB2V2_BOVIN (Q3SZ43    ), UB2V2_CHICK (Q5F3Z3    ), UB2V2_DANRE (Q6PEH5    ), 
UB2V2_HUMAN (Q15819    ), UB2V2_MOUSE (Q9D2M8    ), UB2V2_PONAB (Q5R6C9    ), 
UB2V2_RAT   (Q7M767    ), UB2V2_XENLA (Q7ZYP0    ), UB2WA_DANRE (Q4VBH4    ), 
UBC14_SCHPO (Q9UTN8    ), UBC16_SCHPO (Q9P6I1    ), UBC17_CAEEL (Q11076    ), 
UBC1_MIMIV  (Q5UQC9    ), UBC23_ARATH (Q9ZVX1    ), UBC24_ARATH (Q8VY10    ), 
UBC25_ARATH (Q9LUQ5    ), UBC25_CAEEL (Q93571    ), UBC26_ARATH (Q8GY87    ), 
UBC31_ARATH (Q9C8X7    ), UBC32_ARATH (Q9LSP7    ), UBC33_ARATH (Q9FK29    ), 
UBC34_ARATH (Q9SHI7    ), UBC38_ARATH (Q9C918    ), UBC39_ARATH (F4HPP7    ), 
UBC3_MIMIV  (Q5UQ88    ), UBC4_MIMIV  (Q5UQ40    ), UBC6_ASHGO  (Q74Z34    ), 
UBC6_CANGA  (Q6FQK7    ), UBC6_DEBHA  (Q6BYG4    ), UBC6_KLULA  (Q6CMG6    ), 
UBC6_SCHPO  (O42646    ), UBC6_YEAST  (P33296    ), UBCB_DICDI  (Q94490    ), 
UBE2O_HUMAN (Q9C0C9    ), UBE2O_MOUSE (Q6ZPJ3    ), UBE2V_DICDI (Q54D06    ), 
UBE2W_BOVIN (A6H795    ), UBE2W_HUMAN (Q96B02    ), UBE2W_MOUSE (Q8VDW4    ), 
UBE2W_RAT   (B5DEI4    ), UBE2Z_DANRE (Q6DG60    ), UBE2Z_HUMAN (Q9H832    ), 
UBE2Z_MOUSE (Q3UE37    ), UBE2Z_RAT   (Q3B7D1    ), UBE2Z_XENLA (Q6PCF7    ), 
UBE2Z_XENTR (Q66KB0    ), UE2NL_HUMAN (Q5JXB2    ), UEV1A_ARATH (Q93YP0    ), 
UEV1B_ARATH (Q9CAB6    ), UEV1C_ARATH (Q9SJ44    ), UEV1D_ARATH (Q9SVD7    ), 
UEVLD_DANRE (Q6DBY5    ), UEVLD_HUMAN (Q8IX04    ), UEVLD_MOUSE (Q3U1V6    ), 
UEVLD_XENTR (Q66KB7    ), Y1A1_ENCCU  (Q8SSK3    )
» more

PDB
[Detailed view]
145 PDB

1A3S; 1AYZ; 1C4Z; 1FBV; 1FXT; 1FZY; 1J7D; 1JAS; 1JAT; 1JBB; 1KPS; 1PZV; 1Q34; 1QCQ; 1TTE; 1U9A; 1U9B; 1UR6; 1W4U; 1WZV; 1WZW; 1X23; 1Y6L; 1Y8X; 1YH2; 1YLA; 1YRV; 1Z2U; 1Z3D; 1Z5S; 1ZDN; 2AAK; 2AWF; 2BEP; 2BF8; 2C2V; 2C4P; 2CLW; 2CYX; 2E2C; 2EDI; 2EKE; 2ESK; 2ESO; 2ESP; 2ESQ; 2FUH; 2GJD; 2GRN; 2GRP; 2GRQ; 2GRR; 2KJH; 2KLY; 2LXP; 2O25; 2OB4; 2PE6; 2PX9; 2UCZ; 2VRR; 2XWU; 2Y4W; 2Y9M; 2Y9P; 2YB6; 2YBF; 2YHO; 2Z5D; 3A4S; 3BZH; 3E46; 3EB6; 3F92; 3FN1; 3FSH; 3H8K; 3HCT; 3HCU; 3K9O; 3K9P; 3L1Y; 3L1Z; 3O2U; 3OJ4; 3ONG; 3PTF; 3RCZ; 3RPG; 3RZ3; 3SQV; 3SY2; 3TGD; 3UIN; 3VON; 3W31; 4A49; 4A4B; 4A4C; 4CCG; 4DHI; 4DHJ; 4DHZ; 4II2; 4IP3; 4JQU; 4LAD; 4MDK; 4NR3; 4NRG; 4NRI; 4ONL; 4ONM; 4ONN; 4ORH; 4Q5E; 4Q5H; 4QPL; 4R8P; 4S3O; 4TKP; 4W5V; 4X57; 4Y1L; 4YII; 5A31; 5AIE; 5BNB; 5D1K; 5D1L; 5D1M; 5D2M; 5F6D; 5F6E; 5F6U; 5F6V; 5F6W; 5F6X; 5F6Y; 5HPT; 5IFR; 5JNE; 5KHR; 5L9T; 5L9U
» more

View entry in original PROSITE format
View entry in raw text format (no links)
Direct ScanProsite submission