Entry: PS00195

General information about the entry
Entry name GLUTAREDOXIN_1
Accession number PS00195
Entry type PATTERN
Date APR-1990 (CREATED); DEC-2001 (DATA UPDATE); MAR-2013 (INFO UPDATE).
PROSITE Documentation PDOC00173
Name and characterization of the entry
DescriptionGlutaredoxin active site.
Pattern [LIVMD]-[FYSA]-x(4)-C-[PV]-[FYWH]-C-x(2)-[TAV]-x(2,3)-[LIV].
Numerical results
  • UniProtKB/Swiss-Prot release number: 2013_05, total number of sequence entries in that release: 540052.
  • Total number of hits in UniProtKB/Swiss-Prot: 70 hits in 70 different sequences
  • Number of hits on proteins that are known to belong to the set under consideration: 67 hits in 67 different sequences
  • Number of hits on proteins that could potentially belong to the set under consideration: 0 hits in 0 different sequences
  • Number of false hits (on unrelated proteins): 3 hits in 3 different sequences
  • Number of known missed hits: 40
  • Number of partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences: 0
  • Precision (true hits / (true hits + false positives)): 95.71 %
  • Recall (true hits / (true hits + false negatives)): 62.62 %
Comments
  • Taxonomic range: Archaea, Bacteriophages, Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
  • Maximum known number of repetitions of the pattern in a single protein: 1
  • `Interesting' site in the pattern: 4,disulfide
  • `Interesting' site in the pattern: 7,disulfide
  • VERSION: 1
Cross-references
UniProtKB/Swiss-Prot True positive hits:
GLRX1_BOVIN (P10575), GLRX1_CAMPM (Q8V2V1), GLRX1_CAMPS (Q775X4), 
GLRX1_CHICK (P79764), GLRX1_CWPXB (Q8QMY9), GLRX1_CWPXG (Q80E01), 
GLRX1_ECOLI (P68688), GLRX1_ECTVM (Q8JLF5), GLRX1_GLOIN (B7ZFT1), 
GLRX1_HUMAN (P35754), GLRX1_MOUSE (Q9QUH0), GLRX1_PIG   (P12309), 
GLRX1_RABIT (P12864), GLRX1_RABPU (Q6RZN3), GLRX1_RAT   (Q9ESH6), 
GLRX1_RICBR (Q1RHJ0), GLRX1_RICCN (Q92J02), GLRX1_RICFE (Q4UKL7), 
GLRX1_RICPR (Q9ZDW1), GLRX1_RICTY (Q68XG4), GLRX1_SALTI (P0A1P9), 
GLRX1_SALTY (P0A1P8), GLRX1_SCHPO (O36032), GLRX1_SHIFL (P68689), 
GLRX1_SYNY3 (P74593), GLRX1_VACCA (Q76ZV3), GLRX1_VACCC (P68690), 
GLRX1_VACCP (P68691), GLRX1_VACCT (Q77TL9), GLRX1_VACCW (P68692), 
GLRX1_VAR67 (P32983), GLRX1_YEAST (P25373), GLRX2_ECO57 (P0AC61), 
GLRX2_ECOL6 (P0AC60), GLRX2_ECOLI (P0AC59), GLRX2_SCHPO (Q9UTI2), 
GLRX2_SYNY3 (P73492), GLRX2_YEAST (P17695), GLRX3_ECO57 (P0AC64), 
GLRX3_ECOL6 (P0AC63), GLRX3_ECOLI (P0AC62), GLRX_BPT4   (P00276), 
GLRX_DICDI  (Q54GP8), GLRX_HAEIN  (P45242), GLRX_MIMIV  (Q5UQ14), 
GLRX_NEIMA  (Q9JVU9), GLRX_NEIMB  (Q9JY15), GLRX_PSEAE  (Q9HU55), 
GLRX_RICCO  (P55143), GLRX_SOLLC  (Q9ZR41), GLRX_VERFO  (O81187), 
GRXC2_ARATH (Q9FNE2), GRXC4_ARATH (Q8LFQ6), GRXC4_ORYSJ (Q6K953), 
GRXC6_ORYSJ (P55142), GRXC8_ORYSJ (Q0DAE4), GSPRX_MARGR (B3EWI1), 
PGES2_DANRE (Q7ZUC7), PGES2_HUMAN (Q9H7Z7), PGES2_MACFA (Q9N0A4), 
PGES2_MOUSE (Q8BWM0), PRX5_HAEIN  (P44758), THIO_ARCFU  (O28137), 
THIO_METJA  (Q57755), THIO_METTH  (O26898), THIO_METTM  (P42035), 
YRUB_CLOPA  (P23171)
False negative hits (sequences which belong to the set under consideration, but which have not been picked up by the pattern or profile):
GLRX2_BOVIN (Q32L67), GLRX2_HUMAN (Q9NS18), GLRX2_MOUSE (Q923X4), 
GLRX2_PONAB (Q5RC53), GLRX2_RAT   (Q6AXW1), GLRX8_YEAST (Q05926), 
GLRX_ENCCU  (Q8SUM8), GLRX_VIBCH  (Q9KSW0), GRC10_ARATH (Q29PZ1), 
GRC10_ORYSJ (Q2R076), GRC11_ARATH (Q9LYC6), GRC11_ORYSJ (Q2R075), 
GRC12_ARATH (O82254), GRC12_ORYSJ (Q2R073), GRC13_ARATH (O82255), 
GRC13_ORYSJ (Q0IRB0), GRC14_ARATH (Q9LYC5), GRC14_ORYSJ (Q0IMV4), 
GRC15_ORYSJ (Q2QP86), GRCR1_DROME (Q9VNL4), GRCR1_HUMAN (A8MXD5), 
GRCR1_MOUSE (Q50H32), GRCR2_DROME (Q9W4S1), GRXC1_ARATH (Q8L8T2), 
GRXC1_ORYSJ (Q7G8Y5), GRXC2_ORYSJ (Q0JG89), GRXC3_ARATH (Q9FVX1), 
GRXC3_ORYSJ (Q6K609), GRXC5_ARATH (Q8GWS0), GRXC5_ORYSJ (Q0JDM4), 
GRXC6_ARATH (Q8L9S3), GRXC7_ARATH (Q96305), GRXC7_ORYSJ (Q0DK35), 
GRXC8_ARATH (Q8LF89), GRXC9_ARATH (Q9SGP6), GRXC9_ORYSJ (Q7XIZ1), 
TRXR1_HUMAN (Q16881), TRXR3_HUMAN (Q86VQ6), TRXR3_MOUSE (Q99MD6), 
YTNI_BACSU  (O34639)
False positive hits (sequences which do not belong to the set under consideration):
NUON_CAMC1  (A7ZBF3), SIP5_PICGU  (A5DQJ8), Y3476_BRAJA (Q89PK4)
Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:

[Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format]

Retrieve the sequence logo from the alignment

PDB
[Detailed view]
1AAZ; 1DE1; 1DE2; 1EGO; 1EGR; 1FO5; 1FOV; 1G7O; 1ILB; 1JHB; 1KTE; 1NHO; 1NM3; 1UPY; 1UPZ; 1UQ0; 1UQ1; 1UQ2; 1UQ3; 1UQ6; 1UQ7; 1UQ8; 1UQ9; 1UQH; 1UQI; 1UQJ; 1UQK; 1UQL; 1UQM; 1UQN; 1UQO; 1UQP; 1UQQ; 1Z9H; 2HZE; 2HZF; 2PBJ; 3C1R; 3C1S; 3CTF; 3CTG; 3D4M; 3QMX;

View entry in original PROSITE format
View entry in raw text format (no links)
Direct ScanProsite submission


If you would like to retrieve all the Swiss-Prot entries referenced in the DR lines of this entry (with the exception of false positive hits) , you can enter a file name. These entries will then be saved to a file under this name. (Please note that this temporary file will only be kept for 1 week.)

File name:

Format: Swiss-Prot Fasta

or