Entry: PS00197

Forthcoming changes to the profile format
General information about the entry

Entry name [info] 2FE2S_FER_1
Accession [info] PS00197
Entry type [info] PATTERN
Date [info] APR-1990 (CREATED); DEC-1991 (DATA UPDATE); OCT-2014 (INFO UPDATE).
PROSITE Doc. [info] PDOC00175

Name and characterization of the entry

Description [info] 2Fe-2S ferredoxin-type iron-sulfur binding region signature.
Pattern [info]
C-{C}-{C}-[GA]-{C}-C-[GAST]-{CPDEKRHFYW}-C.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2014_11 which contains 547'085 sequence entries.


Total number of hits 330 in 325 different sequences
Number of true positive hits 270 in 269 different sequences
Number of 'unknown' hits
Number of false positive hits 60 in 56 different sequences
Number of false negative sequences 120
Number of 'partial' sequences 12
Precision (true positives / (true positives + false positives)) 81.82 %
Recall (true positives / (true positives + false negatives)) 69.23 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 2
Site [info] iron_sulfur at position 1
Site [info] iron_sulfur at position 6
Site [info] iron_sulfur at position 9
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
269 sequences

ALDO1_ARATH (Q7G193), ALDO1_MAIZE (O23887), ALDO1_ORYSJ (Q7XH05), 
ALDO2_ARATH (Q7G192), ALDO2_MAIZE (O23888), ALDO2_ORYSJ (Q852M1), 
ALDO3_ARATH (Q7G9P4), ALDO3_ORYSJ (Q852M2), ALDO4_ARATH (Q7G191), 
ALDO4_ORYSJ (Q69R21), ANTDC_ACIAD (O85675), AOXA_BOVIN  (P48034), 
AOXA_CAVPO  (H9TB17), AOXA_HUMAN  (Q06278), AOXA_MACFA  (Q5FB27), 
AOXA_MOUSE  (O54754), AOXA_RABIT  (P80456), AOXA_RAT    (Q9Z0U5), 
AOXB_CAVPO  (H9TB19), AOXB_MACFA  (C4NYZ3), AOXB_MOUSE  (Q5SGK3), 
AOXB_RAT    (Q5QE78), AOXC_MOUSE  (G3X982), AOXC_RAT    (Q5QE80), 
AOXD_CAVPO  (H9TB18), AOXD_MOUSE  (Q3TYQ9), AOXD_RAT    (Q5QE79), 
ASCD_YERPE  (P68641), ASCD_YERPS  (Q66DP5), BENC_ACIAD  (P07771), 
CARAD_PSERE (Q8GI14), CBAB_COMTE  (Q44257), CBDC_BURCE  (Q51603), 
CDHC_PSEU3  (D7REY5), DMPP_ACICP  (Q7WTJ2), DMPP_PSEUF  (P19734), 
FER1_ANAVT  (P00254), FER1_APHFL  (P00244), FER1_AQUAE  (O67065), 
FER1_ARATH  (O04090), FER1_CYACA  (Q9TLW0), FER1_CYAPA  (P17007), 
FER1_DESMC  (P00252), FER1_DUNSA  (P00239), FER1_EQUAR  (P00235), 
FER1_EQUTE  (P00234), FER1_HALMA  (P00217), FER1_HYONI  (P84873), 
FER1_LEPBY  (Q51577), FER1_MAIZE  (P27787), FER1_MESCR  (O04683), 
FER1_NOSS1  (P0A3C7), FER1_NOSSO  (P0A3C8), FER1_ORYSI  (A2YQD9), 
FER1_ORYSJ  (Q0J8M2), FER1_PEA    (P09911), FER1_PHYAM  (P00229), 
FER1_PHYAN  (P00230), FER1_RAPSA  (P14936), FER1_SOLLC  (Q43517), 
FER1_SPIOL  (P00221), FER1_SYNE7  (P0A3D2), FER1_SYNP2  (P31965), 
FER1_SYNP6  (P0A3D3), FER2_APHSA  (P00251), FER2_ARATH  (P16972), 
FER2_CYACA  (P15789), FER2_DESMC  (P00249), FER2_DUNSA  (P00240), 
FER2_EQUAR  (P00237), FER2_EQUTE  (P00236), FER2_HALMA  (Q5UZ63), 
FER2_HYONI  (P84874), FER2_LEPBY  (P46035), FER2_PHYAM  (P00231), 
FER2_PHYAN  (P00232), FER2_RAPSA  (P14937), FER2_SPIOL  (P00224), 
FER2_SYNP6  (P08451), FER3_ARATH  (Q9ZQG8), FER3_CYACA  (P00241), 
FER3_MAIZE  (P27788), FER3_RAPSA  (P14938), FER4_ARATH  (Q9FIA7), 
FER4_RHOCA  (P0CY92), FER4_RHOCB  (D5ARY7), FER5_MAIZE  (P27789), 
FER5_RHOCA  (P37097), FER6_MAIZE  (P94044), FERA_ALOMA  (P81372), 
FERB_ALOMA  (P81373), FERH_ANAVT  (P46046), FERH_MICDP  (P28610), 
FERH_NOSS1  (P11053), FERN_PSEPU  (P23263), FERV_ANAVT  (P46047), 
FERX_PSEPU  (P23103), FER_APHSA   (P00250), FER_ARCLA   (P00223), 
FER_ARTMA   (P00245), FER_ARTPT   (P00246), FER_ATRBE   (P84872), 
FER_BRANA   (P00227), FER_BRUAR   (P83520), FER_BRYMA   (P07838), 
FER_BUMFI   (P13106), FER_CAPAA   (P83527), FER_CAPAN   (Q9ZTS2), 
FER_CHLFR   (P00247), FER_CHLRE   (P07839), FER_COLES   (P00222), 
FER_DATIN   (P68163), FER_DATME   (P68164), FER_DATQU   (P68166), 
FER_DATST   (P68165), FER_DESMC   (P00253), FER_EUGVI   (P22341), 
FER_GLEJA   (P00233), FER_GUITH   (O78510), FER_HALP7   (P15788), 
FER_HALSA   (P00216), FER_HORVU   (P83522), FER_LEULE   (P00225), 
FER_LYCCN   (P83523), FER_MARPO   (P09735), FER_MASLA   (P00248), 
FER_MEDSA   (P00220), FER_ODOSI   (P49522), FER_PALPL   (P07484), 
FER_PANGI   (P85121), FER_PERBI   (P10770), FER_PHYAF   (P83524), 
FER_PHYPA   (O04166), FER_PORPU   (P51320), FER_PORUM   (P00242), 
FER_PYRYE   (Q1XDG7), FER_SAMNI   (P00226), FER_SCEFU   (P56408), 
FER_SCEQU   (P00238), FER_SCOJA   (P83525), FER_SILPR   (P04669), 
FER_SOLAB   (P83585), FER_SOLLS   (P83584), FER_SOLLY   (P83583), 
FER_SOLNI   (P83582), FER_SYNEL   (P0A3D0), FER_SYNLI   (P00255), 
FER_SYNY3   (P27320), FER_SYNY4   (P00243), FER_THAWE   (O98450), 
FER_THEEB   (P0A3C9), FER_THEVL   (P0A3D1), FER_TOBAC   (P83526), 
FER_WHEAT   (P00228), FPOO_METMA  (F1SVE1), FRDB_ECO57  (P0AC49), 
FRDB_ECOL6  (P0AC48), FRDB_ECOLI  (P0AC47), FRDB_HAEIN  (P44893), 
FRDB_HELPJ  (Q9ZMP1), FRDB_HELPY  (O06914), FRDB_PROVU  (P20921), 
FRDB_SHIFL  (P0AC50), FRDB_WOLSU  (P17596), HCRC_THAAR  (O33818), 
IORA_BREDI  (Q51697), KDHB_ARTNI  (O87682), KSHB_MYCS2  (A0R525), 
KSHB_MYCTO  (P9WJ92), KSHB_MYCTU  (P9WJ93), MMOC_METCA  (P22868), 
MOP_DESGI   (Q46509), MSMD_METHY  (Q9X406), NAGAA_RALSP (O52378), 
NDMD_PSEPU  (H9N291), NDOR_PSEPU  (Q52126), NDSFS_EUBBA (Q0QLF3), 
NFXL2_ARATH (Q9FFK8), NICA_PSEPK  (Q88FX9), PAAE_ECOLI  (P76081), 
PDR_BURCE   (P33164), PHT2_PSEPU  (Q05182), POBB_PSEPS  (Q52186), 
PYRK_ARCFU  (O29722), PYRK_METAC  (P58886), PYRK_METBF  (Q46CG8), 
PYRK_METBU  (Q12WN0), PYRK_METJA  (Q58841), PYRK_METKA  (P58887), 
PYRK_METMA  (Q8PW55), PYRK_METTH  (O27280), PYRK_PYRAB  (Q9UXV5), 
PYRK_PYRFU  (P58888), PYRK_PYRHO  (O57738), PYRK_THEKO  (Q5JJ90), 
PYRK_UNCMA  (Q0W8E0), RFBI_SALTY  (P26395), SDHB1_ARATH (Q8LBZ7), 
SDHB2_ARATH (Q8LB02), SDHB3_ARATH (Q9FJP9), SDHB_ASHGO  (Q75CI4), 
SDHB_BOVIN  (Q3T189), SDHB_CAEBR  (A8WPF0), SDHB_CAEEL  (Q09545), 
SDHB_CANGA  (Q6FWS8), SDHB_CHICK  (Q9YHT2), SDHB_CHOCR  (P48932), 
SDHB_CYACA  (P48933), SDHB_DANRE  (A5PL98), SDHB_DICDI  (Q55CC2), 
SDHB_DROME  (P21914), SDHB_HUMAN  (P21912), SDHB_MOUSE  (Q9CQA3), 
SDHB_MYCGR  (O42772), SDHB_PARDE  (Q59662), SDHB_PIG    (Q007T0), 
SDHB_PORPU  (P80477), SDHB_RAT    (P21913), SDHB_RECAM  (P80480), 
SDHB_RICBR  (Q1RGP3), SDHB_RICCN  (Q92JJ8), SDHB_RICFE  (Q4UN71), 
SDHB_RICPR  (Q9ZEA1), SDHB_RICTY  (Q68XS0), SDHB_SCHPO  (P21911), 
SDHB_UROFA  (Q70KF8), SDHB_USTMA  (P32420), SDHB_XENLA  (Q3B8J8), 
SDHB_XENTR  (B0BM36), SDHB_YEAST  (P21801), TFRB_METTM  (D9PUX5), 
TMOF_PSEME  (Q03304), TPDR1_COMSP (Q3C1E0), TPDR2_COMSP (Q3C1D2), 
TSAB1_COMTE (P94680), TSAB2_COMTE (Q9AHG2), VANB_ACIAD  (O24840), 
VANB_PSEPU  (O54037), VANB_PSES9  (P12580), VANB_PSEUH  (O05617), 
XDH1_ARATH  (Q8GUQ8), XDH2_ARATH  (F4JLI5), XDHE_BACSU  (O32143), 
XDH_BOVIN   (P80457), XDH_CALVI   (P08793), XDH_CHICK   (P47990), 
XDH_DICDI   (Q54FB7), XDH_DROME   (P10351), XDH_DROPS   (P22811), 
XDH_DROSU   (P91711), XDH_EMENI   (Q12553), XDH_FELCA   (Q9MYW6), 
XDH_HUMAN   (P47989), XDH_MOUSE   (Q00519), XDH_ORYSJ   (Q6AUV1), 
XDH_RAT     (P22985), XYLA_PSEPU  (P21394), XYLZ_PSEPU  (P23101), 
Y092_METJA  (Q57557), Y1067_METMP (Q6LYC4), Y1309_HAEIN (P45154), 
Y166_BUCBP  (Q89AS6), Y177_BUCAI  (P57274), YAGT_ECO57  (Q8X6I9), 
YAGT_ECOLI  (P77165), YCBX_ECOLI  (P75863), YEAX_ECOLI  (P76254), 
YFAE_ECOL6  (P0ABW4), YFAE_ECOLI  (P0ABW3)
» More

UniProtKB/Swiss-Prot
False negative sequences
120 sequences

CSMI_CHLTE  (O68988), CSMJ_CHLTE  (O68983), CUTC_SULAC  (Q4J6M5), 
DCMS_HYDPS  (P19915), DCMS_OLICO  (P19921), DESET_MYCTO (P9WNE8), 
DESET_MYCTU (P9WNE9), FER_TRIVA   (P21149), FRDB_MYCTO  (P9WN88), 
FRDB_MYCTU  (P9WN89), HCNA_PSEAE  (G3XD67), HCNA_PSEPH  (O85226), 
HCR_ECOLI   (P75824), HNDD_DESFR  (Q46508), HOXU_CUPNH  (P22318), 
MMOC_METTR  (Q53563), MVHD_METTH  (Q50781), MVHD_METTM  (P60238), 
NDUS1_ACACA (Q37373), NDUS1_ARATH (Q9FGI6), NDUS1_BOVIN (P15690), 
NDUS1_DICCI (Q2LCP5), NDUS1_DICDI (Q34312), NDUS1_DROME (Q94511), 
NDUS1_HUMAN (P28331), NDUS1_MESAU (P86203), NDUS1_MOUSE (Q91VD9), 
NDUS1_NEUCR (P24918), NDUS1_PONAB (P0CB67), NDUS1_PONPY (P0CB68), 
NDUS1_RECAM (O21241), NDUS1_SOLTU (Q43644), NQO3_PARDE  (P29915), 
NQO3_THET8  (Q56223), NQRF_ACTP2  (A3MYM7), NQRF_ACTSZ  (A6VLY1), 
NQRF_CHLCV  (Q821Q3), NQRF_CHLFF  (Q255Y6), NQRF_CHLMU  (Q9PLI3), 
NQRF_CHLPN  (Q9Z723), NQRF_CHLTA  (Q3KKV3), NQRF_CHLTR  (O84745), 
NQRF_HAEDU  (Q7VNU4), NQRF_HAEI8  (Q4QP19), NQRF_HAEIE  (A5UAX6), 
NQRF_HAEIG  (A5UFX3), NQRF_HAEIN  (O05012), NQRF_HISS1  (Q0I5Y1), 
NQRF_IDILO  (Q5QYQ8), NQRF_KLEP7  (A6T526), NQRF_MANSM  (Q65VU9), 
NQRF_MARMS  (A6VW13), NQRF_METCA  (Q605A0), NQRF_NEIG1  (Q5F6X5), 
NQRF_NEIM0  (A9M2A6), NQRF_NEIMA  (Q9JVQ3), NQRF_NEIMB  (Q9K0M8), 
NQRF_NEIMF  (A1KSH3), NQRF_PASMU  (Q9CLA6), NQRF_PHOPO  (Q9LCJ1), 
NQRF_PSEA6  (Q15YQ1), NQRF_PSEA7  (A6V3A2), NQRF_PSEAB  (Q02PF8), 
NQRF_PSEAE  (Q9HZL1), NQRF_PSYA2  (Q4FPV2), NQRF_PSYCK  (Q1Q7Z7), 
NQRF_SERP5  (A8GAC4), NQRF_SHEDO  (Q12QK1), NQRF_VIBAL  (Q56584), 
NQRF_VIBAN  (Q75R59), NQRF_VIBC3  (A5F5Y4), NQRF_VIBCB  (Q9RFV6), 
NQRF_VIBCH  (Q9X4Q8), NQRF_VIBPA  (Q9LCJ0), NQRF_VIBVU  (Q8DBJ1), 
NQRF_VIBVY  (Q7MID2), NQRF_YERE8  (A1JNZ2), NQRF_YERP3  (A7FLJ3), 
NQRF_YERPA  (Q1C4D5), NQRF_YERPE  (Q8ZBZ5), NQRF_YERPN  (Q1CLD8), 
NQRF_YERPP  (A4TPL2), NQRF_YERPS  (Q66E01), NUOG2_RHIME (P56914), 
NUOG_BLOFL  (Q7VRV7), NUOG_BUCAI  (P57257), NUOG_BUCAP  (Q8K9Y2), 
NUOG_BUCBP  (Q89AU1), NUOG_ECO57  (Q8XCX2), NUOG_ECOL6  (Q8FFJ9), 
NUOG_ECOLI  (P33602), NUOG_MYCBO  (P59962), NUOG_MYCTO  (P9WIV8), 
NUOG_MYCTU  (P9WIV9), NUOG_PSEAE  (Q9I0J6), NUOG_PSEFL  (Q9KGW3), 
NUOG_PSEPK  (Q88FH2), NUOG_PSESM  (Q87ZQ4), NUOG_RICBR  (Q1RKD2), 
NUOG_RICCN  (Q92G92), NUOG_RICFE  (Q4UK22), NUOG_RICPR  (Q9ZCF6), 
NUOG_RICTY  (Q68VV2), NUOG_SALTI  (P0A1Y5), NUOG_SALTY  (P0A1Y4), 
NUOG_SHEON  (Q8EI34), NUOG_SHIFL  (Q7UC56), NUOG_STRCO  (Q9XAR0), 
NUOG_YERPE  (Q8ZDL2), PHF1_CLOPA  (P29166), SDHB_ECOLI  (P07014), 
SDHB_SALTY  (Q8ZQU2), VHCD_ARCPA  (P84624), VHCD_METVO  (Q00405), 
VHUD_METJA  (P81334), VHUD_METKA  (Q8TXN5), VHUD_METMP  (Q6LWL3), 
VHUD_METVO  (Q00408), XDHC_ECO57  (Q8X6C4), XDHC_ECOLI  (Q46801)
» More

UniProtKB/Swiss-Prot
'Partial' sequences
12 sequences

FER2_PEA    (Q7M258), FER_ANASL   (P83156), FER_PORAE   (P18820), 
FER_PORPP   (P18821), HOXU_RHOOP  (P22659), NQRF_ALTMA  (Q9LCJ3), 
NQRF_COLMA  (Q9K3E1), NQRF_COLPS  (Q9LCJ2), NQRF_PSEHA  (Q9LCJ4), 
NQRF_SHEHA  (Q9LCI8), NQRF_SHEPU  (Q9LCI7), NQRF_VIBMA  (Q9LCI9)
» More

UniProtKB/Swiss-Prot
False positive sequences
56 sequences

ANCHR_HUMAN (Q96K21), BRL1_SCHPO  (Q1MTQ0), CADH1_OCIBA (Q2KNL5), 
DHB2_HUMAN  (P37059), DR3_HHV6U   (Q89660), EFEM_BACSU  (P39596), 
ESP1_ARATH  (Q5IBC5), FAP1H_SCHPO (O74853), FIZ1_HUMAN  (Q96SL8), 
FIZ1_MOUSE  (Q9WTJ4), GUC2A_CAVPO (P70664), GUC2A_DIDVI (P55936), 
GUC2A_HUMAN (Q02747), GUC2A_MOUSE (P33680), GUC2A_NOTAL (Q8R5G9), 
GUC2A_PIG   (P79897), GUC2A_RAT   (P28902), HEPC_PIG    (Q8MJ80), 
KDM2A_HUMAN (Q9Y2K7), KDM2A_MOUSE (P59997), KRA51_HUMAN (Q6L8H4), 
KRA55_HUMAN (Q701N2), KRUC_SHEEP  (P26372), NFX1_DICDI  (Q54BK0), 
NFXL1_XENLA (A0JMY5), RL32_CHLPN  (Q9Z6U7), RL32_CHLTA  (Q3KKN1), 
RL32_CHLTR  (O84816), RN186_BOVIN (Q3T0Y9), RN186_HUMAN (Q9NXI6), 
RNF14_HUMAN (Q9UBS8), RNF14_MOUSE (Q9JI90), RRP44_CAEEL (Q17632), 
SERC4_HUMAN (A6NH21), SERC5_DANRE (Q803X0), SERC5_HUMAN (Q86VE9), 
SERC5_MOUSE (Q8BHJ6), SERC5_RAT   (Q63175), SERIC_MONBE (A9UY97), 
SERIC_NEMVE (A7S4N4), SIVA_HUMAN  (O15304), SIVA_MOUSE  (O54926), 
SIVA_RAT    (P59692), SPIR2_HUMAN (Q8WWL2), SPIR2_MOUSE (Q8K1S6), 
STC_DROME   (P40798), SYFA_CHLAB  (Q5L5A8), SYFA_CHLCV  (Q822B5), 
SYFA_CHLMU  (Q9PL83), SYFA_CHLTA  (Q3KKK3), SYFA_CHLTR  (O84843), 
TNR9_HUMAN  (Q07011), VE6_BPV1    (P06931), VE6_MNPVA   (P30735), 
WDFY2_CAEBR (A8XXC7), WDFY2_CAEEL (Q18964)
» More


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