Entry: PS00226

Forthcoming changes to the profile format
General information about the entry

Entry name [info] IF
Accession [info] PS00226
Entry type [info] PATTERN
Date [info] APR-1990 (CREATED); DEC-2004 (DATA UPDATE); JUN-2014 (INFO UPDATE).
PROSITE Doc. [info] PDOC00198

Name and characterization of the entry

Description [info] Intermediate filaments signature.
Pattern [info]
[IV]-{K}-[TACI]-Y-[RKH]-{E}-[LM]-L-[DE].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2014_07 which contains 546'000 sequence entries.


Total number of hits 310 in 310 different sequences
Number of true positive hits 291 in 291 different sequences
Number of 'unknown' hits
Number of false positive hits 19 in 19 different sequences
Number of false negative sequences 55
Number of 'partial' sequences 9
Precision (true positives / (true positives + false positives)) 93.87 %
Recall (true positives / (true positives + false negatives)) 84.10 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
291 sequences

AINX_BOVIN  (Q08DH7), AINX_HUMAN  (Q16352), AINX_MOUSE  (P46660), 
AINX_RAT    (P23565), AV71_ACAVI  (Q17107), DESM_BOVIN  (O62654), 
DESM_CANFA  (Q5XFN2), DESM_CHICK  (P02542), DESM_HUMAN  (P17661), 
DESM_MESAU  (P02541), DESM_MOUSE  (P31001), DESM_PIG    (P02540), 
DESM_RAT    (P48675), DESM_XENLA  (P23239), GFAP_BOVIN  (Q28115), 
GFAP_CARAU  (P48677), GFAP_DANRE  (Q58EE9), GFAP_HUMAN  (P14136), 
GFAP_MOUSE  (P03995), GFAP_PONAB  (Q5RA72), GFAP_RAT    (P47819), 
IF3T_TORCA  (P23729), IFA1_CAEEL  (P90901), IFA4_CAEEL  (P90900), 
IFB1_CAEEL  (Q19289), IFEA_ASCSU  (P23730), IFEA_HELAS  (P22488), 
IFEA_HELPO  (P16274), IFEB_ASCSU  (P23731), IFEB_HELPO  (P16275), 
IFE_BRALA   (Q04948), ION3_CARAU  (P18520), K118A_POLSE (A1KQY9), 
K118A_XENLA (P08802), K118B_XENLA (Q7SY65), K1C0_XENLA  (P02537), 
K1C10_BOVIN (P06394), K1C10_CANFA (Q6EIZ0), K1C10_HUMAN (P13645), 
K1C10_MOUSE (P02535), K1C10_RAT   (Q6IFW6), K1C11_LAMFL (Q8AWA7), 
K1C11_PROAT (Q5K2P6), K1C12_HUMAN (Q99456), K1C12_MOUSE (Q64291), 
K1C12_RABIT (Q28706), K1C12_RAT   (Q6IFW5), K1C13_HUMAN (P13646), 
K1C13_MOUSE (P08730), K1C13_PROAT (Q5K2P4), K1C13_RAT   (Q6IFV4), 
K1C14_BOVIN (P05785), K1C14_CHICK (Q6PVZ1), K1C14_HUMAN (P02533), 
K1C14_MOUSE (Q61781), K1C14_RAT   (Q6IFV1), K1C15_HUMAN (P19012), 
K1C15_MOUSE (Q61414), K1C15_PROAT (Q5K2P2), K1C15_RAT   (Q6IFV3), 
K1C15_SHEEP (O77727), K1C16_HUMAN (P08779), K1C16_MOUSE (Q9Z2K1), 
K1C17_BOVIN (A1L595), K1C17_HUMAN (Q04695), K1C17_MOUSE (Q9QWL7), 
K1C17_PANTR (A5A6M0), K1C17_RAT   (Q6IFU8), K1C18_ACIBE (Q7SYF8), 
K1C18_CARAU (Q07427), K1C18_DANRE (Q7ZTS4), K1C18_HUMAN (P05783), 
K1C18_MOUSE (P05784), K1C18_ONCMY (O57607), K1C18_RAT   (Q5BJY9), 
K1C18_SCYST (O57611), K1C18_XENTR (Q6P864), K1C19_BOVIN (P08728), 
K1C19_CHICK (O93256), K1C19_HUMAN (P08727), K1C19_MOUSE (P19001), 
K1C19_PONAB (Q5R8S9), K1C19_POTTR (P51856), K1C19_RAT   (Q63279), 
K1C1_XENLA  (P08777), K1C20_BOVIN (A6QQQ9), K1C20_HUMAN (P35900), 
K1C20_MOUSE (Q9D312), K1C20_RAT   (P25030), K1C23_HUMAN (Q9C075), 
K1C23_MOUSE (Q99PS0), K1C24_HUMAN (Q2M2I5), K1C39_HUMAN (Q6A163), 
K1C39_MOUSE (Q6IFX4), K1C39_RAT   (Q6IFW3), K1C40_MOUSE (Q6IFX3), 
K1C40_RAT   (Q6IFW2), K1C42_MOUSE (Q6IFX2), K1C42_RAT   (Q6IFU7), 
K1C4_XENLA  (P05781), K1C5_XENLA  (P08778), K1C9_HUMAN  (P35527), 
K1C9_RAT    (Q8CIS9), K1H1_HUMAN  (Q15323), K1H1_MOUSE  (Q61765), 
K1H1_PANTR  (A5A6M5), K1H2_HUMAN  (Q14532), K1H2_MOUSE  (Q62168), 
K1M1_SHEEP  (P02534), K1M2_SHEEP  (P25690), K22E_CANFA  (Q6EIZ1), 
K22E_HUMAN  (P35908), K22E_MOUSE  (Q3TTY5), K22E_RAT    (Q6IG02), 
K22O_HUMAN  (Q01546), K22O_MOUSE  (Q3UV17), K2C1B_HUMAN (Q7Z794), 
K2C1B_MOUSE (Q6IFZ6), K2C1_CANFA  (Q6EIY9), K2C1_HUMAN  (P04264), 
K2C1_MOUSE  (P04104), K2C1_PANTR  (A5A6M6), K2C1_RAT    (Q6IMF3), 
K2C1_XENLA  (P04266), K2C2_XENLA  (P04265), K2C3_BOVIN  (P04261), 
K2C3_HUMAN  (P12035), K2C3_RABIT  (Q29426), K2C4_BOVIN  (P04260), 
K2C4_HUMAN  (P19013), K2C4_MOUSE  (P07744), K2C4_RAT    (Q6IG00), 
K2C5_BOVIN  (Q5XQN5), K2C5_HUMAN  (P13647), K2C5_MOUSE  (Q922U2), 
K2C5_PANTR  (A5A6M8), K2C5_RAT    (Q6P6Q2), K2C5_XENLA  (P16878), 
K2C6A_HUMAN (P02538), K2C6A_MOUSE (P50446), K2C6A_RAT   (Q4FZU2), 
K2C6B_HUMAN (P04259), K2C6B_MOUSE (Q9Z331), K2C6C_HUMAN (P48668), 
K2C71_BOVIN (Q148H5), K2C71_HUMAN (Q3SY84), K2C71_MOUSE (Q9R0H5), 
K2C71_PONAB (Q5RCY8), K2C72_BOVIN (Q148H8), K2C72_HUMAN (Q14CN4), 
K2C72_MOUSE (Q6IME9), K2C72_RAT   (Q6IG04), K2C73_BOVIN (A7YWK3), 
K2C73_HUMAN (Q86Y46), K2C73_MOUSE (Q6NXH9), K2C73_RAT   (Q6IG03), 
K2C74_HUMAN (Q7RTS7), K2C74_MOUSE (Q6IFZ9), K2C75_BOVIN (Q08D91), 
K2C75_HUMAN (O95678), K2C75_MOUSE (Q8BGZ7), K2C75_RAT   (Q6IG05), 
K2C78_BOVIN (A6QNX5), K2C78_HUMAN (Q8N1N4), K2C79_BOVIN (Q148H7), 
K2C79_HUMAN (Q5XKE5), K2C79_MOUSE (Q8VED5), K2C7_BOVIN  (Q29S21), 
K2C7_HUMAN  (P08729), K2C7_MOUSE  (Q9DCV7), K2C7_PANTR  (A5A6N0), 
K2C7_POTTR  (Q8HZR5), K2C7_RAT    (Q6IG12), K2C8_BOVIN  (P05786), 
K2C8_DANRE  (Q6NWF6), K2C8_HUMAN  (P05787), K2C8_MOUSE  (P11679), 
K2C8_PROAT  (Q5K2N3), K2C8_RAT    (Q10758), K2C8_XENLA  (P08776), 
K2CA_BOVIN  (P04263), K2CB_BOVIN  (P04262), K2CO_CHICK  (O93532), 
K2M2_SHEEP  (P15241), K2M3_SHEEP  (P25691), KRT34_HUMAN (O76011), 
KRT34_MOUSE (Q9D646), KRT35_BOVIN (Q0P5J7), KRT35_HUMAN (Q92764), 
KRT35_MOUSE (Q497I4), KRT35_SHEEP (B0LKP1), KRT36_HUMAN (O76013), 
KRT36_MOUSE (B1AQ75), KRT37_HUMAN (O76014), KRT38_HUMAN (O76015), 
KRT81_BOVIN (Q148H4), KRT81_HUMAN (Q14533), KRT81_MOUSE (Q9ERE2), 
KRT82_HUMAN (Q9NSB4), KRT82_MOUSE (Q99M74), KRT83_BOVIN (A4FUZ0), 
KRT83_HUMAN (P78385), KRT83_MOUSE (Q6IMF0), KRT84_HUMAN (Q9NSB2), 
KRT84_MOUSE (Q99M73), KRT85_HUMAN (P78386), KRT85_MOUSE (Q9Z2T6), 
KRT86_HUMAN (O43790), KRT86_MOUSE (P97861), KT222_BOVIN (Q2KI75), 
KT222_HUMAN (Q8N1A0), KT222_MOUSE (Q8CCX5), KT33A_HUMAN (O76009), 
KT33A_MOUSE (Q8K0Y2), KT33A_PANTR (A5A6P3), KT33B_HUMAN (Q14525), 
KT33B_MOUSE (Q61897), LAML1_XENLA (P09010), LAML2_XENLA (P21910), 
LAML3_XENLA (P10999), LMNA_CHICK  (P13648), LMNA_HUMAN  (P02545), 
LMNA_MOUSE  (P48678), LMNA_PIG    (Q3ZD69), LMNA_RAT    (P48679), 
LMNA_XENLA  (P11048), LMNB1_CHICK (P14731), LMNB1_HUMAN (P20700), 
LMNB1_MOUSE (P14733), LMNB1_RAT   (P70615), LMNB2_CHICK (P14732), 
LMNB2_HUMAN (Q03252), LMNB2_MOUSE (P21619), NEST_DANRE  (P86839), 
NEST_HUMAN  (P48681), NEST_MESAU  (Q9Z1Q1), NEST_MOUSE  (Q6P5H2), 
NEST_RAT    (P21263), NF60_DORPE  (Q01240), NF70_DORPE  (Q01241), 
NFH_HUMAN   (P12036), NFH_MOUSE   (P19246), NFH_RAT     (P16884), 
NFL_BOVIN   (P02548), NFL_COTJA   (Q02916), NFL_HUMAN   (P07196), 
NFL_MOUSE   (P08551), NFL_PIG     (P02547), NFL_PONAB   (Q5R408), 
NFL_RAT     (P19527), NFL_XENLA   (P35616), NFL_XENTR   (B4F721), 
NFM_BOVIN   (O77788), NFM_CHICK   (P16053), NFM_HUMAN   (P07197), 
NFM_MOUSE   (P08553), NFM_PIG     (P08552), NFM_RABIT   (P54938), 
NFM_RAT     (P12839), OV71_ONCVO  (P31732), PERI_BOVIN  (A6QQJ3), 
PERI_HUMAN  (P41219), PERI_MOUSE  (P15331), PERI_RAT    (P21807), 
PERI_XENLA  (P48676), PLST_CARAU  (P31393), RGP51_LYMST (Q6QUW1), 
SYNEM_HUMAN (O15061), SYNEM_MOUSE (Q70IV5), TANA_XENLA  (Q01550), 
TBFA_EPTST  (Q90501), TBFG_EPTST  (Q90502), VIM1_CARAU  (P48671), 
VIM1_XENLA  (P24789), VIM2_CARAU  (P48672), VIM4_XENLA  (P24790), 
VIMB_CARAU  (P48673), VIME_BOVIN  (P48616), VIME_CHICK  (P09654), 
VIME_CHLAE  (P84198), VIME_CRIGR  (P48670), VIME_CYPCA  (Q92155), 
VIME_HUMAN  (P08670), VIME_MACFA  (Q4R4X4), VIME_MESAU  (P02544), 
VIME_MOUSE  (P20152), VIME_ONCMY  (P48674), VIME_PANTR  (Q5R1W8), 
VIME_PIG    (P02543), VIME_RAT    (P31000), XNIF_XENLA  (P35617)
» More

UniProtKB/Swiss-Prot
False negative sequences
55 sequences

BFSP1_BOVIN (Q06002), BFSP1_CHICK (Q06637), BFSP1_HUMAN (Q12934), 
BFSP1_MOUSE (A2AMT1), BFSP1_RAT   (Q02435), BFSP2_BOVIN (Q28177), 
BFSP2_HUMAN (Q13515), BFSP2_MOUSE (Q6NVD9), IFA2_CAEEL  (O02365), 
IFA3_CAEEL  (Q21065), IFB2_CAEEL  (Q19286), IFC1_CAEEL  (O45168), 
IFC2_CAEBR  (Q5WN60), IFC2_CAEEL  (Q21067), IFD1_CAEEL  (Q86DC6), 
IFD2_CAEEL  (Q19782), IFP1_CAEEL  (Q09501), K1C13_ONCMY (Q8JFQ6), 
K1C1_CARAU  (Q90303), K1C24_MOUSE (A1L317), K1C24_RAT   (Q6IFX1), 
K1C25_BOVIN (Q0P5J4), K1C25_CAPHI (Q6R650), K1C25_HUMAN (Q7Z3Z0), 
K1C25_MOUSE (Q8VCW2), K1C25_PANTR (A5A6N2), K1C25_RAT   (Q6IFX0), 
K1C25_SHEEP (Q9BGM5), K1C26_BOVIN (A6H712), K1C26_HUMAN (Q7Z3Y9), 
K1C26_MOUSE (Q3TRJ4), K1C27_BOVIN (Q0P5J6), K1C27_CAPHI (Q6R649), 
K1C27_HUMAN (Q7Z3Y8), K1C27_MOUSE (Q9Z320), K1C27_RAT   (Q6IFW8), 
K1C28_BOVIN (Q148H6), K1C28_HUMAN (Q7Z3Y7), K1C28_MOUSE (A6BLY7), 
K1C40_BOVIN (A7YWM2), K1C40_HUMAN (Q6A162), K1C9_CANFA  (O18740), 
K1C9_MOUSE  (Q6RHW0), K2C1B_RAT   (Q6IG01), K2C74_BOVIN (A3KN27), 
K2C80_BOVIN (A0JND2), K2C80_HUMAN (Q6KB66), K2C80_MOUSE (Q0VBK2), 
K2C80_RAT   (Q6IMF1), KR87P_HUMAN (A6NCN2), LAM0_DROME  (P08928), 
LAMC_DROME  (Q03427), LMN1_CAEEL  (Q21443), SYNCI_HUMAN (Q9H7C4), 
SYNCI_MOUSE (Q9EPM5)
» More

UniProtKB/Swiss-Prot
'Partial' sequences
9 sequences

K1C19_MESAU (P86246), K1C20_PIG   (Q29218), K1C3_XENLA  (P05782), 
K2C8_MESAU  (P86247), K2C8_POTTR  (Q28810), K2M1_SHEEP  (P02539), 
KRT_CEREL   (P86498), NFH_PIG     (P12037), VIME_SHEEP  (Q9MZA9)
» More

UniProtKB/Swiss-Prot
False positive sequences
19 sequences

ADDB_DESRM  (A4J4E2), AIM6_CANGA  (Q6FWH9), ATPG_DESVH  (Q72E03), 
BAH_STRHY   (Q01109), CEMA_PSEAK  (Q3ZJ15), FAB1D_ARATH (Q9XID0), 
GLYL3_HUMAN (Q5SZD4), LIX1_CHICK  (Q8UVV7), LIX1_HUMAN  (Q8N485), 
LIX1_MOUSE  (Q6P566), LPH_RABIT   (P09849), MEND_NOCSJ  (A1SE17), 
OGRL1_XENTR (A2VCV0), PPR36_ARATH (Q0WKV3), RFBF_BACSU  (O06486), 
RS10_NOVAD  (Q2G8Y1), RS10_SACD2  (Q21M58), TYSY_SYMTH  (Q67JQ1), 
YO91_CAEEL  (P41842)
» More

PDB
[Detailed view]
9 PDB

1GK4; 1GK6; 1X8Y; 2XV5; 3TNU; 3TYY; 3V4Q; 3V4W; 3V5B

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