Entry: PS00232

General information about the entry

Entry name [info] CADHERIN_1
Accession [info] PS00232
Entry type [info] PATTERN
Date [info] APR-1990 (CREATED); APR-1990 (DATA UPDATE); MAR-2016 (INFO UPDATE).
PROSITE Doc. [info] PDOC00205

Name and characterization of the entry

Description [info] Cadherin domain signature.
Pattern [info]
[LIV]-x-[LIV]-x-D-x-N-D-[NH]-x-P.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2016_04 which contains 550'960 sequence entries.


Total number of hits 1'485 in 305 different sequences
Number of true positive hits 1'485 in 305 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 15
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 99.00 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes
Maximum number of repetitions [info] 23
Site [info] calcium(?) at position 5
Site [info] calcium(?) at position 7
Site [info] calcium(?) at position 8
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
305 sequences

CAD10_CHICK (P79995), CAD10_HUMAN (Q9Y6N8), CAD10_MOUSE (P70408), 
CAD11_CHICK (O93319), CAD11_HUMAN (P55287), CAD11_MOUSE (P55288), 
CAD12_HUMAN (P55289), CAD12_MOUSE (Q5RJH3), CAD13_BOVIN (Q3B7N0), 
CAD13_CHICK (P33150), CAD13_HUMAN (P55290), CAD13_MOUSE (Q9WTR5), 
CAD13_PONAB (Q5R5W6), CAD15_HUMAN (P55291), CAD15_MOUSE (P33146), 
CAD16_HUMAN (O75309), CAD16_MOUSE (O88338), CAD16_RABIT (Q28634), 
CAD17_HUMAN (Q12864), CAD17_MOUSE (Q9R100), CAD17_RAT   (P55281), 
CAD18_BOVIN (Q08DJ5), CAD18_HUMAN (Q13634), CAD19_HUMAN (Q9H159), 
CAD20_CHICK (Q8QGH3), CAD20_HUMAN (Q9HBT6), CAD20_MOUSE (Q9Z0M3), 
CAD20_RAT   (Q5DWV1), CAD20_XENLA (Q91838), CAD22_HUMAN (Q9UJ99), 
CAD22_MOUSE (Q9WTP5), CAD22_RAT   (Q63315), CAD23_HUMAN (Q9H251), 
CAD23_MOUSE (Q99PF4), CAD23_RAT   (P58365), CAD24_HUMAN (Q86UP0), 
CAD24_MOUSE (Q6PFX6), CAD26_HUMAN (Q8IXH8), CAD26_MOUSE (P59862), 
CAD2A_XENLA (P33147), CAD2B_XENLA (P20310), CAD86_DROME (Q9VGW1), 
CAD87_DROME (Q9VGG5), CAD89_DROME (Q9VEU1), CADE_DROME  (Q24298), 
CADH1_BOVIN (Q6R8F2), CADH1_CANLF (F1PAA9), CADH1_CHICK (P08641), 
CADH1_HUMAN (P12830), CADH1_MOUSE (P09803), CADH1_PONAB (Q5RAX1), 
CADH1_RAT   (Q9R0T4), CADH1_XENLA (P30944), CADH2_BOVIN (P19534), 
CADH2_CALJA (B0KW95), CADH2_CHICK (P10288), CADH2_CRIGR (O55075), 
CADH2_DANRE (Q90275), CADH2_HUMAN (P19022), CADH2_MOUSE (P15116), 
CADH2_OTOGA (B4USZ0), CADH2_PONAB (Q5R9X1), CADH2_RAT   (Q9Z1Y3), 
CADH2_RHIFE (B2KI42), CADH3_BOVIN (P19535), CADH3_CAEEL (P34616), 
CADH3_HUMAN (P22223), CADH3_MOUSE (P10287), CADH3_PIG   (O18926), 
CADH4_CAEEL (Q19319), CADH4_CHICK (P24503), CADH4_HUMAN (P55283), 
CADH4_MOUSE (P39038), CADH4_RAT   (Q63149), CADH4_XENLA (P79883), 
CADH5_BOVIN (Q6URK6), CADH5_CHICK (Q8AYD0), CADH5_HUMAN (P33151), 
CADH5_MOUSE (P55284), CADH5_PIG   (O02840), CADH6_BOVIN (Q3SWX5), 
CADH6_CHICK (Q90762), CADH6_HUMAN (P55285), CADH6_MOUSE (P97326), 
CADH6_RAT   (P55280), CADH7_CHICK (Q90763), CADH7_HUMAN (Q9ULB5), 
CADH7_MOUSE (Q8BM92), CADH7_RAT   (Q5DWV2), CADH8_HUMAN (P55286), 
CADH8_MOUSE (P97291), CADH8_RAT   (O54800), CADH9_HUMAN (Q9ULB4), 
CADH9_MOUSE (P70407), CADHB_XENLA (P33152), CADHF_XENLA (P33148), 
CADHK_CHICK (P33145), CADN2_DROME (Q9VJB6), CADN_DROME  (O15943), 
CDHR1_BOVIN (Q8WN91), CDHR1_CHICK (Q8UVJ7), CDHR1_DANRE (Q6B3P0), 
CDHR1_HUMAN (Q96JP9), CDHR1_MOUSE (Q8VHP6), CDHR1_RAT   (Q91XU7), 
CDHR1_XENLA (Q6B457), CDHR2_HUMAN (Q9BYE9), CDHR2_MOUSE (E9Q7P9), 
CDHR4_HUMAN (A6H8M9), CDHR5_HUMAN (Q9HBB8), CDHR5_MOUSE (Q8VHF2), 
CDHR5_RAT   (Q9JIK1), CELR1_HUMAN (Q9NYQ6), CELR1_MOUSE (O35161), 
CELR2_HUMAN (Q9HCU4), CELR2_MOUSE (Q9R0M0), CELR2_RAT   (Q9QYP2), 
CELR3_HUMAN (Q9NYQ7), CELR3_MOUSE (Q91ZI0), CELR3_RAT   (O88278), 
DSC1_BOVIN  (Q01107), DSC1_HUMAN  (Q08554), DSC1_MOUSE  (P55849), 
DSC2_BOVIN  (P33545), DSC2_HUMAN  (Q02487), DSC2_MOUSE  (P55292), 
DSC3_BOVIN  (Q28060), DSC3_HUMAN  (Q14574), DSC3_MOUSE  (P55850), 
DSG1A_MOUSE (Q61495), DSG1B_MOUSE (Q7TSF1), DSG1C_MOUSE (Q7TSF0), 
DSG1_BOVIN  (Q03763), DSG1_CANLF  (Q9GKQ8), DSG1_HUMAN  (Q02413), 
DSG1_PIG    (Q3BDI7), DSG2_HUMAN  (Q14126), DSG2_MOUSE  (O55111), 
DSG3_CANLF  (Q7YRU7), DSG3_HUMAN  (P32926), DSG3_MOUSE  (O35902), 
DSG4_HUMAN  (Q86SJ6), DSG4_MOUSE  (Q7TMD7), DSG4_RAT    (Q6W3B0), 
DS_DROME    (Q24292), FAT1_HUMAN  (Q14517), FAT2_DROME  (Q9VW71), 
FAT2_HUMAN  (Q9NYQ8), FAT2_MOUSE  (Q5F226), FAT2_RAT    (O88277), 
FAT3_HUMAN  (Q8TDW7), FAT3_MOUSE  (Q8BNA6), FAT3_RAT    (Q8R508), 
FAT4_HUMAN  (Q6V0I7), FAT4_MOUSE  (Q2PZL6), FAT_DROME   (P33450), 
HMR1_CAEEL  (Q967F4), PC11X_GORGO (Q6X862), PC11X_HUMAN (Q9BZA7), 
PC11X_PANPA (Q6WYY1), PC11X_PANTR (Q71M42), PC11X_PIG   (Q6KEQ9), 
PC11X_PONPY (Q6WXV7), PC11Y_HUMAN (Q9BZA8), PCD10_HUMAN (Q9P2E7), 
PCD12_HUMAN (Q9NPG4), PCD12_MOUSE (O55134), PCD15_CHICK (Q0ZM14), 
PCD15_HUMAN (Q96QU1), PCD15_MOUSE (Q99PJ1), PCD16_HUMAN (Q96JQ0), 
PCD16_MOUSE (E9PVD3), PCD16_RAT   (D4ACX8), PCD17_HUMAN (O14917), 
PCD18_BOVIN (A7MB46), PCD18_HUMAN (Q9HCL0), PCD18_MOUSE (Q8VHR0), 
PCD19_HUMAN (Q8TAB3), PCD19_MOUSE (Q80TF3), PCD20_HUMAN (Q8N6Y1), 
PCD20_MOUSE (Q8BIZ0), PCD23_HUMAN (Q6V1P9), PCDA1_HUMAN (Q9Y5I3), 
PCDA1_PANTR (Q5DRF5), PCDA2_HUMAN (Q9Y5H9), PCDA2_PANTR (Q5DRF0), 
PCDA3_HUMAN (Q9Y5H8), PCDA3_PANTR (Q5DRE9), PCDA4_HUMAN (Q9UN74), 
PCDA4_MOUSE (O88689), PCDA4_PANTR (Q5DRE8), PCDA4_RAT   (Q767I8), 
PCDA5_HUMAN (Q9Y5H7), PCDA5_PANTR (Q5DRE7), PCDA6_HUMAN (Q9UN73), 
PCDA6_PANTR (Q5DRE6), PCDA7_HUMAN (Q9UN72), PCDA7_PANTR (Q5DRE5), 
PCDA8_HUMAN (Q9Y5H6), PCDA8_PANTR (Q5DRE4), PCDA9_HUMAN (Q9Y5H5), 
PCDA9_MOUSE (Q91Y11), PCDA9_PANTR (Q5DRE3), PCDAA_HUMAN (Q9Y5I2), 
PCDAA_MOUSE (Q91Y20), PCDAA_PANTR (Q5DRF4), PCDAB_HUMAN (Q9Y5I1), 
PCDAB_PANTR (Q5DRF3), PCDAC_HUMAN (Q9UN75), PCDAC_PANTR (Q5DRF2), 
PCDAD_HUMAN (Q9Y5I0), PCDAD_PANTR (Q5DRF1), PCDB1_HUMAN (Q9Y5F3), 
PCDB1_PANTR (Q5DRE0), PCDB2_HUMAN (Q9Y5E7), PCDB2_PANTR (Q5DRD2), 
PCDB3_HUMAN (Q9Y5E6), PCDB3_PANTR (Q5DRD1), PCDB4_HUMAN (Q9Y5E5), 
PCDB4_PANTR (Q5DRD0), PCDB5_HUMAN (Q9Y5E4), PCDB5_PANTR (Q5DRC9), 
PCDB6_HUMAN (Q9Y5E3), PCDB6_PANTR (Q5DRC8), PCDB7_HUMAN (Q9Y5E2), 
PCDB7_PANTR (Q5DRC7), PCDB8_HUMAN (Q9UN66), PCDB8_PANTR (Q5DRC6), 
PCDB9_HUMAN (Q9Y5E1), PCDB9_PANTR (Q5DRC4), PCDBA_HUMAN (Q9UN67), 
PCDBA_PANTR (Q5DRD9), PCDBB_HUMAN (Q9Y5F2), PCDBB_PANTR (Q5DRD8), 
PCDBC_HUMAN (Q9Y5F1), PCDBC_PANTR (Q5DRD7), PCDBD_HUMAN (Q9Y5F0), 
PCDBD_PANTR (Q5DRD6), PCDBE_HUMAN (Q9Y5E9), PCDBE_MOUSE (Q6PB90), 
PCDBE_PANTR (Q5DRD5), PCDBF_HUMAN (Q9Y5E8), PCDBF_PANTR (Q5DRD3), 
PCDBG_HUMAN (Q9NRJ7), PCDBH_PANTR (Q5DRC3), PCDBI_HUMAN (Q96TA0), 
PCDBI_MOUSE (Q91Y02), PCDBI_PANTR (Q5DRD4), PCDC1_HUMAN (Q9H158), 
PCDC1_PANTR (Q5DRE2), PCDC2_HUMAN (Q9Y5I4), PCDC2_PANTR (Q5DRE1), 
PCDG1_HUMAN (Q9Y5H4), PCDG1_PANTR (Q5DRC2), PCDG2_HUMAN (Q9Y5H1), 
PCDG2_PANTR (Q5DRB8), PCDG3_HUMAN (Q9Y5H0), PCDG3_PANTR (Q5DRB7), 
PCDG4_HUMAN (Q9Y5G9), PCDG4_MOUSE (Q91XY4), PCDG4_PANTR (Q5DRB6), 
PCDG5_HUMAN (Q9Y5G8), PCDG5_PANTR (Q5DRB5), PCDG6_HUMAN (Q9Y5G7), 
PCDG6_PANTR (Q5DRB4), PCDG7_HUMAN (Q9Y5G6), PCDG7_PANTR (Q5DRB3), 
PCDG8_HUMAN (Q9Y5G5), PCDG8_PANTR (Q5DRB2), PCDG9_HUMAN (Q9Y5G4), 
PCDG9_PANTR (Q5DRB1), PCDGA_HUMAN (Q9Y5H3), PCDGA_PANTR (Q5DRC1), 
PCDGB_HUMAN (Q9Y5H2), PCDGB_PANTR (Q5DRC0), PCDGC_HUMAN (O60330), 
PCDGC_PANTR (Q5DRB9), PCDGD_HUMAN (Q9Y5G3), PCDGD_PANTR (Q5DRB0), 
PCDGE_HUMAN (Q9Y5G2), PCDGE_PANTR (Q5DRA9), PCDGF_HUMAN (Q9Y5G1), 
PCDGG_HUMAN (Q9UN71), PCDGG_PANTR (Q5DRA8), PCDGH_HUMAN (Q9Y5G0), 
PCDGH_PANTR (Q5DRA7), PCDGI_HUMAN (Q9Y5F9), PCDGI_PANTR (Q5DRA6), 
PCDGJ_HUMAN (Q9Y5F8), PCDGJ_PANTR (Q5DRA5), PCDGK_HUMAN (Q9UN70), 
PCDGK_PANTR (Q5DRA4), PCDGL_HUMAN (Q9Y5F7), PCDGL_PANTR (Q5DRA3), 
PCDGM_HUMAN (Q9Y5F6), PCDGM_PANTR (Q5DRA2), PCDH1_HUMAN (Q08174), 
PCDH3_RAT   (Q63418), PCDH7_HUMAN (O60245), PCDH8_HUMAN (O95206), 
PCDH8_MOUSE (Q7TSK3), PCDH8_RAT   (D3ZE55), PCDH9_HUMAN (Q9HC56), 
PCDL_ACRMI  (B8V7Q1), STAN_DROME  (Q9V5N8)
» more

UniProtKB/Swiss-Prot
False negative sequences
15 sequences

CAD96_DROME (Q9VBW3), CDHR3_HUMAN (Q6ZTQ4), CDHR3_MOUSE (Q8BL00), 
CSTN1_DROME (Q9V498), CSTN1_HUMAN (O94985), CSTN1_MOUSE (Q9EPL2), 
CSTN2_HUMAN (Q9H4D0), CSTN2_MOUSE (Q9ER65), CSTN2_RAT   (Q8VDA1), 
CSTN3_BOVIN (Q0VCN6), CSTN3_HUMAN (Q9BQT9), CSTN3_MOUSE (Q99JH7), 
CSTN3_PONAB (Q5R9Q9), CSTN3_RAT   (Q8R553), HMU_HALWD   (Q18DN4)
» more

PDB
[Detailed view]
43 PDB

1EDH; 1FF5; 1L3W; 1NCJ; 1Q1P; 1WYJ; 2A4E; 2A62; 2O72; 2QVF; 2QVI; 2V37; 2WCP; 2WHV; 2YQG; 2YST; 3K5R; 3K5S; 3LND; 3LNE; 3LNF; 3LNG; 3LNH; 3LNI; 3MVS; 3PPE; 3Q2L; 3Q2N; 3Q2V; 3Q2W; 3QRB; 3UBH; 4APX; 4AQ8; 4AQA; 4AQE; 4AXW; 4NQQ; 4NUM; 4NUP; 4NUQ; 4OY9; 4QD2
» more

View entry in original PROSITE format
View entry in raw text format (no links)
Direct ScanProsite submission