Entry: PS00236

General information about the entry

Entry name [info] NEUROTR_ION_CHANNEL
Accession [info] PS00236
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED; 01-NOV-1997 DATA UPDATE; 05-JUL-2017 INFO UPDATE.
PROSITE Doc. [info] PDOC00209

Name and characterization of the entry

Description [info] Neurotransmitter-gated ion-channels signature.
Pattern [info] 
C-x-[LIVMFQ]-x-[LIVMF]-x(2)-[FY]-P-x-D-x(3)-C.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2017_07 which contains 555'100 sequence entries.


Total number of hits 243 in 243 different sequences
Number of true positive hits 243 in 243 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 5
Number of 'partial' sequences 5
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 97.98 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Site [info] disulfide at position 1
Site [info] disulfide at position 12
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 243 sequences 

5HT3A_CAVPO (O70212    ), 5HT3A_HUMAN (P46098    ), 5HT3A_MOUSE (P23979    ), 

5HT3A_RAT   (P35563    ), 5HT3C_HUMAN (Q8WXA8    ), 5HT3E_HUMAN (A5X5Y0    ), 
ACH10_CHICK (Q9I8C7    ), ACH10_HUMAN (Q9GZZ6    ), ACH10_RAT   (Q9JLB5    ), 
ACH1_CAEBR  (A8WQK3    ), ACH1_CAEEL  (P48180    ), ACH1_DROME  (P09478    ), 
ACH1_MANSE  (P91766    ), ACH1_SCHGR  (P23414    ), ACH23_CAEEL (G5EG88    ), 
ACH2_CAEEL  (P48181    ), ACH2_DROME  (P17644    ), ACH3_CAEEL  (P54244    ), 
ACH3_DROME  (P04755    ), ACH4_CAEEL  (O76554    ), ACH4_DROME  (P25162    ), 
ACH5_CAEEL  (Q23022    ), ACH6_CAEEL  (Q9N587    ), ACH7_CAEEL  (Q27218    ), 
ACH8_CAEBR  (Q60S81    ), ACH8_CAEEL  (Q9U298    ), ACH91_ONCMY (Q8JFN7    ), 
ACH92_ONCMY (Q68RJ7    ), ACHA2_CHICK (P09480    ), ACHA2_HUMAN (Q15822    ), 
ACHA2_MOUSE (Q91X60    ), ACHA2_PANTR (Q5IS52    ), ACHA2_RAT   (P12389    ), 
ACHA3_BOVIN (Q07263    ), ACHA3_CARAU (P18845    ), ACHA3_CHICK (P09481    ), 
ACHA3_HUMAN (P32297    ), ACHA3_MOUSE (Q8R4G9    ), ACHA3_RAT   (P04757    ), 
ACHA4_CHICK (P09482    ), ACHA4_HUMAN (P43681    ), ACHA4_MOUSE (O70174    ), 
ACHA4_MUSPF (Q19AE6    ), ACHA4_PANTR (Q5IS77    ), ACHA4_RAT   (P09483    ), 
ACHA5_BOVIN (Q8SPU7    ), ACHA5_CHICK (P26152    ), ACHA5_HUMAN (P30532    ), 
ACHA5_MOUSE (Q2MKA5    ), ACHA5_PANTR (Q5IS51    ), ACHA5_RAT   (P20420    ), 
ACHA6_CHICK (P49581    ), ACHA6_HUMAN (Q15825    ), ACHA6_MOUSE (Q9R0W9    ), 
ACHA6_PANTR (Q5IS76    ), ACHA6_RAT   (P43143    ), ACHA7_BOVIN (P54131    ), 
ACHA7_CHICK (P22770    ), ACHA7_HUMAN (P36544    ), ACHA7_MACMU (Q866A2    ), 
ACHA7_MOUSE (P49582    ), ACHA7_RAT   (Q05941    ), ACHA9_CHICK (Q9PTS8    ), 
ACHA9_HUMAN (Q9UGM1    ), ACHA9_RAT   (P43144    ), ACHAA_XENLA (P22456    ), 
ACHAB_XENLA (P05377    ), ACHA_BOVIN  (P02709    ), ACHA_CHICK  (P09479    ), 
ACHA_CRORS  (P54248    ), ACHA_DANRE  (Q98880    ), ACHA_ERICO  (P54249    ), 
ACHA_FELCA  (P54250    ), ACHA_HERIC  (P54251    ), ACHA_HUMAN  (P02708    ), 
ACHA_MOUSE  (P04756    ), ACHA_NAJNA  (P14143    ), ACHA_NATTE  (P14144    ), 
ACHA_RAT    (P25108    ), ACHA_TETCF  (P02710    ), ACHA_TORMA  (P02711    ), 
ACHB2_CARAU (P19370    ), ACHB2_CHICK (P09484    ), ACHB2_HUMAN (P17787    ), 
ACHB2_MOUSE (Q9ERK7    ), ACHB2_RAT   (P12390    ), ACHB3_CHICK (P43679    ), 
ACHB3_HUMAN (Q05901    ), ACHB3_MOUSE (Q8BMN3    ), ACHB3_PANTR (Q5IS75    ), 
ACHB3_RAT   (P12391    ), ACHB4_BOVIN (Q8SPU6    ), ACHB4_CHICK (P26153    ), 
ACHB4_HUMAN (P30926    ), ACHB4_MOUSE (Q8R493    ), ACHB4_RAT   (P12392    ), 
ACHB_BOVIN  (P04758    ), ACHB_HUMAN  (P11230    ), ACHB_MOUSE  (P09690    ), 
ACHB_RAT    (P25109    ), ACHB_TETCF  (P02712    ), ACHB_XENLA  (P49579    ), 
ACHD_BOVIN  (P04759    ), ACHD_CHICK  (P02717    ), ACHD_HUMAN  (Q07001    ), 
ACHD_MOUSE  (P02716    ), ACHD_RAT    (P25110    ), ACHD_TETCF  (P02718    ), 
ACHD_XENLA  (P09628    ), ACHE_BOVIN  (P02715    ), ACHE_HUMAN  (Q04844    ), 
ACHE_MOUSE  (P20782    ), ACHE_RAT    (P09660    ), ACHE_XENLA  (P49580    ), 
ACHG_BOVIN  (P13536    ), ACHG_CHICK  (P02713    ), ACHG_HUMAN  (P07510    ), 
ACHG_MOUSE  (P04760    ), ACHG_RAT    (P18916    ), ACHG_TETCF  (P02714    ), 
ACHG_XENLA  (P05376    ), ACHN2_CARAU (P13908    ), ACHN3_CARAU (P18257    ), 
ACHX_ONCVO  (P54247    ), ACR2_CAEEL  (P48182    ), ACR3_CAEEL  (Q93149    ), 
ACR7_CAEEL  (P45963    ), ARKA_DICDI  (Q54HC6    ), CRFM7_HUMAN (Q494W8    ), 
CUP4_CAEBR  (A8XF54    ), CUP4_CAEEL  (P34271    ), GBR1_CAEEL  (G5ECJ0    ), 
GBRA1_BOVIN (P08219    ), GBRA1_CHICK (P19150    ), GBRA1_HUMAN (P14867    ), 
GBRA1_MACFA (Q4R534    ), GBRA1_MOUSE (P62812    ), GBRA1_PONAB (Q5R6B2    ), 
GBRA1_RAT   (P62813    ), GBRA2_BOVIN (P10063    ), GBRA2_HUMAN (P47869    ), 
GBRA2_MOUSE (P26048    ), GBRA2_PONAB (Q5RCC5    ), GBRA2_RAT   (P23576    ), 
GBRA3_BOVIN (P10064    ), GBRA3_HUMAN (P34903    ), GBRA3_MOUSE (P26049    ), 
GBRA3_RAT   (P20236    ), GBRA4_BOVIN (P20237    ), GBRA4_HUMAN (P48169    ), 
GBRA4_MOUSE (Q9D6F4    ), GBRA4_RAT   (P28471    ), GBRA5_BOVIN (Q08E50    ), 
GBRA5_HUMAN (P31644    ), GBRA5_MOUSE (Q8BHJ7    ), GBRA5_RAT   (P19969    ), 
GBRA6_CHICK (Q90845    ), GBRA6_HUMAN (Q16445    ), GBRA6_MOUSE (P16305    ), 
GBRA6_RAT   (P30191    ), GBRAL_DROME (Q24352    ), GBRB1_BOVIN (P08220    ), 
GBRB1_HUMAN (P18505    ), GBRB1_MOUSE (P50571    ), GBRB1_RAT   (P15431    ), 
GBRB2_BOVIN (P0C2W5    ), GBRB2_HUMAN (P47870    ), GBRB2_MACMU (D1LYT2    ), 
GBRB2_MOUSE (P63137    ), GBRB2_RAT   (P63138    ), GBRB3_CHICK (P19019    ), 
GBRB3_DROME (Q08832    ), GBRB3_HUMAN (P28472    ), GBRB3_MOUSE (P63080    ), 
GBRB3_RAT   (P63079    ), GBRB4_CHICK (P24045    ), GBRB_CAEEL  (O18276    ), 
GBRB_DROME  (P25123    ), GBRB_DROSI  (Q9BLY8    ), GBRB_LYMST  (P26714    ), 
GBRB_MUSDO  (Q75NA5    ), GBRD_HUMAN  (O14764    ), GBRD_MOUSE  (P22933    ), 
GBRD_RAT    (P18506    ), GBRE_HUMAN  (P78334    ), GBRE_RAT    (Q9ES14    ), 
GBRG1_HUMAN (Q8N1C3    ), GBRG1_MOUSE (Q9R0Y8    ), GBRG1_RAT   (P23574    ), 
GBRG2_BOVIN (P22300    ), GBRG2_CHICK (P21548    ), GBRG2_HUMAN (P18507    ), 
GBRG2_MOUSE (P22723    ), GBRG2_PONAB (Q5REA1    ), GBRG2_RAT   (P18508    ), 
GBRG3_HUMAN (Q99928    ), GBRG3_MOUSE (P27681    ), GBRG3_RAT   (P28473    ), 
GBRG4_CHICK (P34904    ), GBRP_BOVIN  (Q5EA06    ), GBRP_HUMAN  (O00591    ), 
GBRP_MOUSE  (Q8QZW7    ), GBRP_RAT    (O09028    ), GBRR1_HUMAN (P24046    ), 
GBRR1_MOUSE (P56475    ), GBRR1_RAT   (P50572    ), GBRR2_BOVIN (Q0II76    ), 
GBRR2_HUMAN (P28476    ), GBRR2_MOUSE (P56476    ), GBRR2_RAT   (P47742    ), 
GBRR3_HUMAN (A8MPY1    ), GBRR3_RAT   (P50573    ), GBRT_HUMAN  (Q9UN88    ), 
GBRT_MOUSE  (Q9JLF1    ), GLRA1_BOVIN (P57695    ), GLRA1_DANRE (O93430    ), 
GLRA1_HUMAN (P23415    ), GLRA1_MOUSE (Q64018    ), GLRA1_RAT   (P07727    ), 
GLRA2_HUMAN (P23416    ), GLRA2_MOUSE (Q7TNC8    ), GLRA2_RAT   (P22771    ), 
GLRA3_HUMAN (O75311    ), GLRA3_MOUSE (Q91XP5    ), GLRA3_RAT   (P24524    ), 
GLRA4_HUMAN (Q5JXX5    ), GLRA4_MOUSE (Q61603    ), GLRB4_CAEEL (Q09453    ), 
GLRB_BOVIN  (Q9GJS9    ), GLRB_HUMAN  (P48167    ), GLRB_MOUSE  (P48168    ), 
GLRB_RAT    (P20781    ), GLUCB_CAEEL (Q17328    ), GLUCB_HAECO (P91730    ), 
GLUCL_CAEEL (G5EBR3    ), GLUCL_DROME (Q94900    ), LGC4_CAEBR  (A8XNX8    ), 
LGC4_CAEEL  (P54245    ), LGC50_CAEEL (P41849    ), PBO5_CAEEL  (G5ECT0    ), 
PBO6_CAEEL  (Q19351    ), ZACN_CANLF  (Q866Y9    ), ZACN_HUMAN  (Q401N2    )
» more

UniProtKB/Swiss-Prot
False negative sequences		 5 sequences 

5HT3B_HUMAN (O95264    ), 5HT3B_MOUSE (Q9JHJ5    ), 5HT3B_RAT   (Q9JJ16    ), 

5HT3D_HUMAN (Q70Z44    ), ACR5_CAEEL  (P54246    )
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 5 sequences 

ACHA_ELEEL  (P09688    ), ACHB_CHICK  (P16005    ), ACHB_ELEEL  (P09689    ), 

ACHD_ELEEL  (P09691    ), ACHG_ELEEL  (P09692    )
» more

PDB
[Detailed view]		 27 PDB

2BG9; 2QC1; 3JAD; 3JAE; 3JAF; 3RHW; 3RI5; 3RIA; 3RIF; 4AQ5; 4AQ9; 4BOG; 4BOI; 4BON; 4BOO; 4BOR; 4BOT; 4COF; 4D01; 4PIR; 4TNV; 4TNW; 4UXU; 4UY2; 5CFB; 5FJV; 5KXI
» more

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