Entry: PS00236

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General information about the entry

Entry name [info] NEUROTR_ION_CHANNEL
Accession [info] PS00236
Entry type [info] PATTERN
Date [info] APR-1990 (CREATED); NOV-1997 (DATA UPDATE); JUN-2014 (INFO UPDATE).
PROSITE Doc. [info] PDOC00209

Name and characterization of the entry

Description [info] Neurotransmitter-gated ion-channels signature.
Pattern [info]
C-x-[LIVMFQ]-x-[LIVMF]-x(2)-[FY]-P-x-D-x(3)-C.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2014_07 which contains 546'000 sequence entries.


Total number of hits 242 in 242 different sequences
Number of true positive hits 242 in 242 different sequences
Number of 'unknown' hits
Number of false positive hits
Number of false negative sequences 5
Number of 'partial' sequences 5
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 97.98 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Site [info] disulfide at position 1
Site [info] disulfide at position 12
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
242 sequences

5HT3A_CAVPO (O70212), 5HT3A_HUMAN (P46098), 5HT3A_MOUSE (P23979), 
5HT3A_RAT   (P35563), 5HT3C_HUMAN (Q8WXA8), 5HT3E_HUMAN (A5X5Y0), 
ACH10_CHICK (Q9I8C7), ACH10_HUMAN (Q9GZZ6), ACH10_RAT   (Q9JLB5), 
ACH1_CAEBR  (A8WQK3), ACH1_CAEEL  (P48180), ACH1_DROME  (P09478), 
ACH1_MANSE  (P91766), ACH1_SCHGR  (P23414), ACH23_CAEEL (G5EG88), 
ACH2_CAEEL  (P48181), ACH2_DROME  (P17644), ACH3_CAEEL  (P54244), 
ACH3_DROME  (P04755), ACH4_CAEEL  (O76554), ACH4_DROME  (P25162), 
ACH5_CAEEL  (Q23022), ACH6_CAEEL  (Q9N587), ACH7_CAEEL  (Q27218), 
ACH8_CAEBR  (Q60S81), ACH8_CAEEL  (Q9U298), ACH91_ONCMY (Q8JFN7), 
ACH92_ONCMY (Q68RJ7), ACHA2_CHICK (P09480), ACHA2_HUMAN (Q15822), 
ACHA2_MOUSE (Q91X60), ACHA2_PANTR (Q5IS52), ACHA2_RAT   (P12389), 
ACHA3_BOVIN (Q07263), ACHA3_CARAU (P18845), ACHA3_CHICK (P09481), 
ACHA3_HUMAN (P32297), ACHA3_MOUSE (Q8R4G9), ACHA3_RAT   (P04757), 
ACHA4_CHICK (P09482), ACHA4_HUMAN (P43681), ACHA4_MOUSE (O70174), 
ACHA4_MUSPF (Q19AE6), ACHA4_PANTR (Q5IS77), ACHA4_RAT   (P09483), 
ACHA5_BOVIN (Q8SPU7), ACHA5_CHICK (P26152), ACHA5_HUMAN (P30532), 
ACHA5_MOUSE (Q2MKA5), ACHA5_PANTR (Q5IS51), ACHA5_RAT   (P20420), 
ACHA6_CHICK (P49581), ACHA6_HUMAN (Q15825), ACHA6_MOUSE (Q9R0W9), 
ACHA6_PANTR (Q5IS76), ACHA6_RAT   (P43143), ACHA7_BOVIN (P54131), 
ACHA7_CHICK (P22770), ACHA7_HUMAN (P36544), ACHA7_MACMU (Q866A2), 
ACHA7_MOUSE (P49582), ACHA7_RAT   (Q05941), ACHA9_CHICK (Q9PTS8), 
ACHA9_HUMAN (Q9UGM1), ACHA9_RAT   (P43144), ACHAA_XENLA (P22456), 
ACHAB_XENLA (P05377), ACHA_BOVIN  (P02709), ACHA_CHICK  (P09479), 
ACHA_CRORS  (P54248), ACHA_DANRE  (Q98880), ACHA_ERICO  (P54249), 
ACHA_FELCA  (P54250), ACHA_HERIC  (P54251), ACHA_HUMAN  (P02708), 
ACHA_MOUSE  (P04756), ACHA_NAJNA  (P14143), ACHA_NATTE  (P14144), 
ACHA_RAT    (P25108), ACHA_TORCA  (P02710), ACHA_TORMA  (P02711), 
ACHB2_CARAU (P19370), ACHB2_CHICK (P09484), ACHB2_HUMAN (P17787), 
ACHB2_MOUSE (Q9ERK7), ACHB2_RAT   (P12390), ACHB3_CHICK (P43679), 
ACHB3_HUMAN (Q05901), ACHB3_MOUSE (Q8BMN3), ACHB3_PANTR (Q5IS75), 
ACHB3_RAT   (P12391), ACHB4_BOVIN (Q8SPU6), ACHB4_CHICK (P26153), 
ACHB4_HUMAN (P30926), ACHB4_MOUSE (Q8R493), ACHB4_RAT   (P12392), 
ACHB_BOVIN  (P04758), ACHB_HUMAN  (P11230), ACHB_MOUSE  (P09690), 
ACHB_RAT    (P25109), ACHB_TORCA  (P02712), ACHB_XENLA  (P49579), 
ACHD_BOVIN  (P04759), ACHD_CHICK  (P02717), ACHD_HUMAN  (Q07001), 
ACHD_MOUSE  (P02716), ACHD_RAT    (P25110), ACHD_TORCA  (P02718), 
ACHD_XENLA  (P09628), ACHE_BOVIN  (P02715), ACHE_HUMAN  (Q04844), 
ACHE_MOUSE  (P20782), ACHE_RAT    (P09660), ACHE_XENLA  (P49580), 
ACHG_BOVIN  (P13536), ACHG_CHICK  (P02713), ACHG_HUMAN  (P07510), 
ACHG_MOUSE  (P04760), ACHG_RAT    (P18916), ACHG_TORCA  (P02714), 
ACHG_XENLA  (P05376), ACHN2_CARAU (P13908), ACHN3_CARAU (P18257), 
ACHX_ONCVO  (P54247), ACR2_CAEEL  (P48182), ACR3_CAEEL  (Q93149), 
ACR7_CAEEL  (P45963), ARKA_DICDI  (Q54HC6), CRFM7_HUMAN (Q494W8), 
CUP4_CAEBR  (A8XF54), CUP4_CAEEL  (P34271), GBR1_CAEEL  (G5ECJ0), 
GBRA1_BOVIN (P08219), GBRA1_CHICK (P19150), GBRA1_HUMAN (P14867), 
GBRA1_MACFA (Q4R534), GBRA1_MOUSE (P62812), GBRA1_PONAB (Q5R6B2), 
GBRA1_RAT   (P62813), GBRA2_BOVIN (P10063), GBRA2_HUMAN (P47869), 
GBRA2_MOUSE (P26048), GBRA2_PONAB (Q5RCC5), GBRA2_RAT   (P23576), 
GBRA3_BOVIN (P10064), GBRA3_HUMAN (P34903), GBRA3_MOUSE (P26049), 
GBRA3_RAT   (P20236), GBRA4_BOVIN (P20237), GBRA4_HUMAN (P48169), 
GBRA4_MOUSE (Q9D6F4), GBRA4_RAT   (P28471), GBRA5_BOVIN (Q08E50), 
GBRA5_HUMAN (P31644), GBRA5_MOUSE (Q8BHJ7), GBRA5_RAT   (P19969), 
GBRA6_CHICK (Q90845), GBRA6_HUMAN (Q16445), GBRA6_MOUSE (P16305), 
GBRA6_RAT   (P30191), GBRAL_DROME (Q24352), GBRB1_BOVIN (P08220), 
GBRB1_HUMAN (P18505), GBRB1_MOUSE (P50571), GBRB1_RAT   (P15431), 
GBRB2_BOVIN (P0C2W5), GBRB2_HUMAN (P47870), GBRB2_MACMU (D1LYT2), 
GBRB2_MOUSE (P63137), GBRB2_RAT   (P63138), GBRB3_CHICK (P19019), 
GBRB3_DROME (Q08832), GBRB3_HUMAN (P28472), GBRB3_MOUSE (P63080), 
GBRB3_RAT   (P63079), GBRB4_CHICK (P24045), GBRB_CAEEL  (O18276), 
GBRB_DROME  (P25123), GBRB_DROSI  (Q9BLY8), GBRB_LYMST  (P26714), 
GBRB_MUSDO  (Q75NA5), GBRD_HUMAN  (O14764), GBRD_MOUSE  (P22933), 
GBRD_RAT    (P18506), GBRE_HUMAN  (P78334), GBRE_RAT    (Q9ES14), 
GBRG1_HUMAN (Q8N1C3), GBRG1_MOUSE (Q9R0Y8), GBRG1_RAT   (P23574), 
GBRG2_BOVIN (P22300), GBRG2_CHICK (P21548), GBRG2_HUMAN (P18507), 
GBRG2_MOUSE (P22723), GBRG2_PONAB (Q5REA1), GBRG2_RAT   (P18508), 
GBRG3_HUMAN (Q99928), GBRG3_MOUSE (P27681), GBRG3_RAT   (P28473), 
GBRG4_CHICK (P34904), GBRP_BOVIN  (Q5EA06), GBRP_HUMAN  (O00591), 
GBRP_MOUSE  (Q8QZW7), GBRP_RAT    (O09028), GBRR1_HUMAN (P24046), 
GBRR1_MOUSE (P56475), GBRR1_RAT   (P50572), GBRR2_BOVIN (Q0II76), 
GBRR2_HUMAN (P28476), GBRR2_MOUSE (P56476), GBRR2_RAT   (P47742), 
GBRR3_HUMAN (A8MPY1), GBRR3_RAT   (P50573), GBRT_HUMAN  (Q9UN88), 
GBRT_MOUSE  (Q9JLF1), GLRA1_BOVIN (P57695), GLRA1_DANRE (O93430), 
GLRA1_HUMAN (P23415), GLRA1_MOUSE (Q64018), GLRA1_RAT   (P07727), 
GLRA2_HUMAN (P23416), GLRA2_MOUSE (Q7TNC8), GLRA2_RAT   (P22771), 
GLRA3_HUMAN (O75311), GLRA3_MOUSE (Q91XP5), GLRA3_RAT   (P24524), 
GLRA4_HUMAN (Q5JXX5), GLRA4_MOUSE (Q61603), GLRB4_CAEEL (Q09453), 
GLRB_BOVIN  (Q9GJS9), GLRB_HUMAN  (P48167), GLRB_MOUSE  (P48168), 
GLRB_RAT    (P20781), GLUCB_CAEEL (Q17328), GLUCB_HAECO (P91730), 
GLUCL_DROME (Q94900), LGC4_CAEBR  (A8XNX8), LGC4_CAEEL  (P54245), 
LGC50_CAEEL (P41849), PBO5_CAEEL  (G5ECT0), PBO6_CAEEL  (Q19351), 
ZACN_CANFA  (Q866Y9), ZACN_HUMAN  (Q401N2)
» More

UniProtKB/Swiss-Prot
False negative sequences
5 sequences

5HT3B_HUMAN (O95264), 5HT3B_MOUSE (Q9JHJ5), 5HT3B_RAT   (Q9JJ16), 
5HT3D_HUMAN (Q70Z44), ACR5_CAEEL  (P54246)
» More

UniProtKB/Swiss-Prot
'Partial' sequences
5 sequences

ACHA_ELEEL  (P09688), ACHB_CHICK  (P16005), ACHB_ELEEL  (P09689), 
ACHD_ELEEL  (P09691), ACHG_ELEEL  (P09692)
» More

PDB
[Detailed view]
11 PDB

2BG9; 2QC1; 4AQ5; 4AQ9; 4BOG; 4BOG0; 4BOI; 4BON; 4BOO; 4BOR; 4BOT

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