Entry: PS00239

General information about the entry
Entry name RECEPTOR_TYR_KIN_II
Accession number PS00239
Entry type PATTERN
Date APR-1990 (CREATED); NOV-1995 (DATA UPDATE); MAR-2013 (INFO UPDATE).
PROSITE Documentation PDOC00212
Name and characterization of the entry
DescriptionReceptor tyrosine kinase class II signature.
Pattern [DN]-[LIV]-Y-x(3)-Y-Y-R.
Numerical results
  • UniProtKB/Swiss-Prot release number: 2013_05, total number of sequence entries in that release: 540052.
  • Total number of hits in UniProtKB/Swiss-Prot: 53 hits in 53 different sequences
  • Number of hits on proteins that are known to belong to the set under consideration: 52 hits in 52 different sequences
  • Number of hits on proteins that could potentially belong to the set under consideration: 0 hits in 0 different sequences
  • Number of false hits (on unrelated proteins): 1 hits in 1 different sequences
  • Number of known missed hits: 2
  • Number of partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences: 2
  • Precision (true hits / (true hits + false positives)): 98.11 %
  • Recall (true hits / (true hits + false negatives)): 96.30 %
Comments
  • Taxonomic range: Eukaryotes, Eukaryotic viruses
  • Maximum known number of repetitions of the pattern in a single protein: 1
  • `Interesting' site in the pattern: 5,phosphorylation
  • VERSION: 1
Cross-references
UniProtKB/Swiss-Prot True positive hits:
7LESS_DROME (P13368), 7LESS_DROVI (P20806), ALK_HUMAN   (Q9UM73), 
ALK_MOUSE   (P97793), DDR1_HUMAN  (Q08345), DDR1_MOUSE  (Q03146), 
DDR1_PANTR  (Q7YR43), DDR1_RAT    (Q63474), DDR2_HUMAN  (Q16832), 
DDR2_MOUSE  (Q62371), HTK7_HYDVU  (Q25197), IGF1R_BOVIN (Q05688), 
IGF1R_HUMAN (P08069), IGF1R_MOUSE (Q60751), IGF1R_RAT   (P24062), 
IGF1R_XENLA (O73798), ILPR_BRALA  (O02466), INSRR_CAVPO (P14617), 
INSRR_HUMAN (P14616), INSRR_MOUSE (Q9WTL4), INSRR_RAT   (Q64716), 
INSR_AEDAE  (Q93105), INSR_DROME  (P09208), INSR_HUMAN  (P06213), 
INSR_MOUSE  (P15208), INSR_RAT    (P15127), INSR_XENLA  (Q9PVZ4), 
LTK_HUMAN   (P29376), LTK_MOUSE   (P08923), MIPR_LYMST  (Q25410), 
NTRK1_CHICK (Q91009), NTRK1_HUMAN (P04629), NTRK1_MOUSE (Q3UFB7), 
NTRK1_RAT   (P35739), NTRK2_CHICK (Q91987), NTRK2_HUMAN (Q16620), 
NTRK2_MOUSE (P15209), NTRK2_RAT   (Q63604), NTRK3_CHICK (Q91044), 
NTRK3_HUMAN (Q16288), NTRK3_MACFA (Q5IFJ9), NTRK3_MOUSE (Q6VNS1), 
NTRK3_PANTR (Q5IS37), NTRK3_PIG   (P24786), NTRK3_RAT   (Q03351), 
NTRK3_SAIBB (Q5IS82), ROR1_DROME  (Q24488), ROS1_CHICK  (P08941), 
ROS1_HUMAN  (P08922), ROS_AVISU   (P00529), RTK2_GEOCY  (P42159), 
TRK1_LYMST  (O76997)
False negative hits (sequences which belong to the set under consideration, but which have not been picked up by the pattern or profile):
PTK7_HUMAN  (Q13308), PTK7_MOUSE  (Q8BKG3)
`Potential' hits (partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences):
IGF1R_PIG   (Q29000), INSR_MACMU  (Q28516)
False positive hits (sequences which do not belong to the set under consideration):
OST1A_ORYSJ (Q0DJC5)
Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:

[Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format]

Retrieve the sequence logo from the alignment

PDB
[Detailed view]		 1IRK; 1M7N; 1P4O; 2OJ9; 3D94; 3EKN; 3ETA; 3I81; 3L9P; 3LCS; 3LCT; 3LVP; 3LW0; 3NW5; 3NW6; 3NW7; 3O23; 3QQU; 3V5Q; 4ASZ; 4AT4; 4AT5; 4F0I; 4GT5;

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