Entry: PS00247

General information about the entry
Entry name HBGF_FGF
Accession number PS00247
Entry type PATTERN
Date APR-1990 (CREATED); DEC-2004 (DATA UPDATE); MAR-2013 (INFO UPDATE).
PROSITE Documentation PDOC00220
Name and characterization of the entry
DescriptionHBGF/FGF family signature.
Pattern G-x-[LIM]-x-[STAGP]-x(6,7)-[DENA]-C-x-[FLM]-x-[EQ]-x(6)-Y.
Numerical results
  • UniProtKB/Swiss-Prot release number: 2013_05, total number of sequence entries in that release: 540052.
  • Total number of hits in UniProtKB/Swiss-Prot: 101 hits in 101 different sequences
  • Number of hits on proteins that are known to belong to the set under consideration: 101 hits in 101 different sequences
  • Number of hits on proteins that could potentially belong to the set under consideration: 0 hits in 0 different sequences
  • Number of false hits (on unrelated proteins): 0 hits in 0 different sequences
  • Number of known missed hits: 4
  • Number of partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences: 1
  • Precision (true hits / (true hits + false positives)): 100.00 %
  • Recall (true hits / (true hits + false negatives)): 96.19 %
Comments
  • Taxonomic range: Eukaryotes, Eukaryotic viruses
  • Maximum known number of repetitions of the pattern in a single protein: 1
  • VERSION: 1
Cross-references
UniProtKB/Swiss-Prot True positive hits:
FG17_DANRE  (Q6SJP8), FGF10_HUMAN (O15520), FGF10_MOUSE (O35565), 
FGF10_RAT   (P70492), FGF11_HUMAN (Q92914), FGF11_MOUSE (P70378), 
FGF12_HUMAN (P61328), FGF12_MOUSE (P61329), FGF12_RAT   (P61150), 
FGF13_HUMAN (Q92913), FGF13_MOUSE (P70377), FGF13_PONAB (Q5RDS9), 
FGF13_RAT   (Q9ERW3), FGF13_XENLA (A6P7H6), FGF14_HUMAN (Q92915), 
FGF14_MOUSE (P70379), FGF14_RAT   (Q8R5L7), FGF15_MOUSE (O35622), 
FGF16_HUMAN (O43320), FGF16_MOUSE (Q9ESL8), FGF16_RAT   (O54769), 
FGF17_HUMAN (O60258), FGF17_MOUSE (P63075), FGF17_RAT   (P63076), 
FGF18_BOVIN (Q0VCA0), FGF18_HUMAN (O76093), FGF18_MOUSE (O89101), 
FGF18_RAT   (O88182), FGF19_HUMAN (O95750), FGF1_BOVIN  (P03968), 
FGF1_CAPCA  (Q9N1S8), FGF1_CHICK  (P19596), FGF1_CYNPY  (Q6I6M7), 
FGF1_HUMAN  (P05230), FGF1_MESAU  (P34004), FGF1_MOUSE  (P61148), 
FGF1_NOTVI  (Q7SIF8), FGF1_PIG    (P20002), FGF1_PONAB  (Q5NVQ3), 
FGF1_RAT    (P61149), FGF1_SHEEP  (Q7M303), FGF1_XENLA  (Q6GLR6), 
FGF20_HUMAN (Q9NP95), FGF20_MOUSE (Q9ESL9), FGF20_RAT   (Q9EST9), 
FGF21_HUMAN (Q9NSA1), FGF21_MOUSE (Q9JJN1), FGF22_MOUSE (Q9ESS2), 
FGF23_MOUSE (Q9EPC2), FGF23_RAT   (Q8VI82), FGF2_BOVIN  (P03969), 
FGF2_CAVPO  (Q60487), FGF2_CHICK  (P48800), FGF2_HUMAN  (P09038), 
FGF2_MONDO  (P48798), FGF2_MOUSE  (P15655), FGF2_PANTR  (Q5IS69), 
FGF2_RABIT  (P48799), FGF2_RAT    (P13109), FGF2_SHEEP  (P20003), 
FGF2_XENLA  (P12226), FGF3_CHICK  (P48801), FGF3_DANRE  (P48802), 
FGF3_HUMAN  (P11487), FGF3_MOUSE  (P05524), FGF3_XENLA  (P36386), 
FGF4A_XENLA (P48805), FGF4B_XENLA (P48806), FGF4_BOVIN  (P48803), 
FGF4_CHICK  (P48804), FGF4_HUMAN  (P08620), FGF4_MOUSE  (P11403), 
FGF5_BOVIN  (A0MTF4), FGF5_CANFA  (Q20FD0), FGF5_HUMAN  (P12034), 
FGF5_MOUSE  (P15656), FGF5_RAT    (P48807), FGF6_HUMAN  (P10767), 
FGF6_MOUSE  (P21658), FGF7_CANFA  (P79150), FGF7_CEREL  (Q5D0X0), 
FGF7_HUMAN  (P21781), FGF7_MOUSE  (P36363), FGF7_PIG    (Q9N198), 
FGF7_PONAB  (Q5RAY8), FGF7_RAT    (Q02195), FGF7_SHEEP  (P48808), 
FGF8B_DANRE (Q805B2), FGF8_CANFA  (O62682), FGF8_CHICK  (Q90722), 
FGF8_HUMAN  (P55075), FGF8_MOUSE  (P37237), FGF9_DIDAL  (Q3ZFI5), 
FGF9_HUMAN  (P31371), FGF9_MOUSE  (P54130), FGF9_PIG    (Q95L12), 
FGF9_RAT    (P36364), FGF9_XENLA  (Q91875), FGFH_NPVAC  (P41444), 
FGFH_NPVOP  (O10284), KGFL1_HUMAN (Q2TVT4)
False negative hits (sequences which belong to the set under consideration, but which have not been picked up by the pattern or profile):
FGF22_HUMAN (Q9HCT0), FGF23_HUMAN (Q9GZV9), FGF23_TETNG (Q5MK86), 
LE756_CAEEL (Q11184)
`Potential' hits (partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences):
FGF1_CANFA  (P18651)
Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:

[Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format]

Retrieve the sequence logo from the alignment

PDB
[Detailed view]		 1AFC; 1AXM; 1BAR; 1BAS; 1BFB; 1BFC; 1BFF; 1BFG; 1BLA; 1BLD; 1CVS; 1DJS; 1DZC; 1DZD; 1E0O; 1EV2; 1EVT; 1FGA; 1FMM; 1FQ9; 1G82; 1HKN; 1IHK; 1II4; 1IIL; 1IJT; 1JQZ; 1JT4; 1JTC; 1JY0; 1K5U; 1K5V; 1NUN; 1P63; 1PWA; 1PZZ; 1Q03; 1Q04; 1Q1U; 1QCT; 1QQK; 1QQL; 1RG8; 1RML; 1RY7; 1YTO; 1Z2V; 1Z4S; 2AFG; 2AQZ; 2AXM; 2BFH; 2ERM; 2FDB; 2FGF; 2HW9; 2HWA; 2HWM; 2HZ9; 2J3P; 2K43; 2K4A; 2K8R; 2KI4; 2KI6; 2LDN; 2NTD; 2P23; 2Q9X; 2RQ9; 2UUS; 3B9U; 3BA4; 3BA5; 3BA7; 3BAD; 3BAG; 3BAH; 3BAO; 3BAQ; 3BAU; 3BAV; 3BB2; 3CQA; 3CRG; 3CRH; 3CRI; 3CU1; 3F1R; 3FJ8; 3FJA; 3FJB; 3FJC; 3FJD; 3FJK; 3HBW; 3HOM; 3JUT; 3K1X; 3OJ2; 3OJM; 3OJV; 3UD7; 3UD8; 3UD9; 3UDA; 4DCK; 4FGF;

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