Entry: PS00248

General information about the entry
Entry name NGF_1
Accession number PS00248
Entry type PATTERN
Date APR-1990 (CREATED); APR-2006 (DATA UPDATE); MAR-2013 (INFO UPDATE).
PROSITE Documentation PDOC00221
Name and characterization of the entry
DescriptionNerve growth factor family signature.
Pattern [GSRE]-C-[KRL]-G-[LIVT]-[DE]-x(3)-[YW]-x-S-x-C.
Numerical results
  • UniProtKB/Swiss-Prot release number: 2013_05, total number of sequence entries in that release: 540052.
  • Total number of hits in UniProtKB/Swiss-Prot: 115 hits in 115 different sequences
  • Number of hits on proteins that are known to belong to the set under consideration: 115 hits in 115 different sequences
  • Number of hits on proteins that could potentially belong to the set under consideration: 0 hits in 0 different sequences
  • Number of false hits (on unrelated proteins): 0 hits in 0 different sequences
  • Number of known missed hits: 1
  • Number of partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences: 25
  • Precision (true hits / (true hits + false positives)): 100.00 %
  • Recall (true hits / (true hits + false negatives)): 99.14 %
Comments
  • Taxonomic range: Eukaryotes
  • Maximum known number of repetitions of the pattern in a single protein: 1
  • `Interesting' site in the pattern: 2,disulfide
  • `Interesting' site in the pattern: 12,disulfide
  • VERSION: 2
Cross-references
UniProtKB/Swiss-Prot True positive hits:
BDNF_ACRDU  (Q1X706), BDNF_ACRJA  (Q1X702), BDNF_AILFU  (O97759), 
BDNF_AILME  (Q6LCI5), BDNF_ANISC  (Q1X700), BDNF_ASPME  (Q1HN40), 
BDNF_BOACO  (Q1X708), BDNF_BOVIN  (Q95106), BDNF_CALRI  (Q1X6Z7), 
BDNF_CANCA  (Q1X707), BDNF_CANFA  (Q7YRB4), BDNF_CAVPO  (O70183), 
BDNF_CHABO  (Q1X6Z6), BDNF_CHICK  (P25429), BDNF_CORCI  (Q1X711), 
BDNF_CYCMA  (Q8QG74), BDNF_CYLRU  (Q1X701), BDNF_CYPCA  (Q90322), 
BDNF_EPICE  (Q1X710), BDNF_EPIST  (Q1HN42), BDNF_ERYCC  (Q1HN34), 
BDNF_ERYCN  (Q1X6Z8), BDNF_ERYJO  (Q1HN32), BDNF_ERYJY  (Q1HN36), 
BDNF_EUNNO  (Q1X709), BDNF_EXIPL  (Q1X704), BDNF_FELCA  (Q9TST3), 
BDNF_HELMA  (O18753), BDNF_HORSE  (Q0EAB7), BDNF_HUMAN  (P23560), 
BDNF_LICTR  (Q1HN31), BDNF_LIPVE  (Q49M28), BDNF_LOXBI  (Q1HN33), 
BDNF_MACLB  (P25431), BDNF_MACMU  (Q06225), BDNF_MORSI  (Q1X703), 
BDNF_MOUSE  (P21237), BDNF_PANTR  (Q5IS78), BDNF_PIG    (P14082), 
BDNF_PROLO  (O18755), BDNF_RAJCL  (P25430), BDNF_RAMSP  (Q1X6Z5), 
BDNF_RAT    (P23363), BDNF_SANME  (Q1X705), BDNF_SPECI  (Q4L0Y3), 
BDNF_TROHA  (Q1X6Z9), BDNF_URSAR  (O18752), BDNF_URSTH  (Q3SAT7), 
BDNF_XENLA  (P25432), BDNF_XENUN  (Q1HN38), BDNF_XIPMA  (Q02193), 
NGFV1_AZEFE (Q2XXL6), NGFV1_DEMVE (A6MFL5), NGFV1_HOPST (Q3HXY0), 
NGFV1_NAJSP (Q5YF90), NGFV1_NOTSC (Q3HXY7), NGFV1_OXYMI (Q3HXZ1), 
NGFV1_PSEAU (Q3HXY3), NGFV1_PSETE (Q3HXY9), NGFV1_TROCA (Q3HXX8), 
NGFV2_DEMVE (A6MFL6), NGFV2_HOPST (Q3HXX9), NGFV2_NAJSP (Q5YF89), 
NGFV2_OXYMI (Q3HXZ0), NGFV2_PSEAU (Q3HXY2), NGFV2_PSETE (Q3HXY8), 
NGFV2_TROCA (Q3HXX7), NGFV3_DEMVE (A6MFL7), NGFV3_NOTSC (Q3HXY5), 
NGFV3_PSEAU (Q3HXY1), NGFV3_TROCA (Q3HXX6), NGFV4_TROCA (Q3HXX5), 
NGFV5_TROCA (Q3HXX4), NGFV_BOTJR  (Q90W38), NGFV_BUNMU  (P34128), 
NGFV_CRODU  (Q9DEZ9), NGFV_DABRR  (P30894), NGFV_MACLB  (P25428), 
NGFV_NAJAT  (P61898), NGFV_NAJKA  (P61899), NGFV_NAJNA  (P01140), 
NGFV_OXYSC  (Q3I5F4), NGFV_PSEPO  (Q3HXY4), NGFV_RHING  (Q1W7Q6), 
NGF_BOVIN   (P13600), NGF_CAVPO   (P19093), NGF_CHICK   (P05200), 
NGF_DANRE   (Q6YBR5), NGF_GORGO   (Q9N2F0), NGF_HUMAN   (P01138), 
NGF_MASNA   (P20675), NGF_MOUSE   (P01139), NGF_PANTR   (Q9N2F1), 
NGF_PIG     (Q29074), NGF_PONPY   (Q9N2E9), NGF_RAT     (P25427), 
NGF_SAIBB   (Q5ISB0), NGF_XENLA   (P21617), NGF_XIPMA   (P34129), 
NTF3_BOVIN  (Q08DT3), NTF3_CHICK  (P25433), NTF3_FELCA  (Q9TST2), 
NTF3_HUMAN  (P20783), NTF3_MOUSE  (P20181), NTF3_PIG    (Q06AV0), 
NTF3_RAJCL  (P25434), NTF3_RAT    (P18280), NTF3_XENLA  (P25435), 
NTF4_HUMAN  (P34130), NTF4_MACLB  (P25436), NTF4_MOUSE  (Q80VU4), 
NTF4_RAT    (P34131), NTF4_XENLA  (P24727), NTF7_CYPCA  (O93474), 
NTF7_DANRE  (O73797)
False negative hits (sequences which belong to the set under consideration, but which have not been picked up by the pattern or profile):
NGFV2_NOTSC (Q3HXY6)
`Potential' hits (partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences):
NTF3_ACRDU  (Q1X6Y9), NTF3_ACRJA  (Q1X6Y5), NTF3_ANISC  (Q1X6Y3), 
NTF3_ASPME  (Q1KN21), NTF3_BOACO  (Q1X6Z1), NTF3_CALRI  (Q1X6Y0), 
NTF3_CANCA  (Q1X6Z0), NTF3_CEREL  (Q95150), NTF3_CHABO  (Q1X6X9), 
NTF3_CORCI  (Q1X6Z4), NTF3_CYLRU  (Q1X6Y4), NTF3_EPICE  (Q1X6Z3), 
NTF3_EPIST  (Q1KN23), NTF3_ERYCC  (Q1KN16), NTF3_ERYCN  (Q1X6Y1), 
NTF3_ERYJO  (Q1KN12), NTF3_EUNNO  (Q1X6Z2), NTF3_EXIPL  (Q1X6Y7), 
NTF3_LICTR  (Q1KN10), NTF3_LOXBI  (Q1KN14), NTF3_MORSI  (Q1X6Y6), 
NTF3_RAMSP  (Q1X6X8), NTF3_SANME  (Q1X6Y8), NTF3_TROHA  (Q1X6Y2), 
NTF3_XENUN  (Q1KN19)
Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:

[Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format]

Retrieve the sequence logo from the alignment

PDB
[Detailed view]		 1B8K; 1B8M; 1B98; 1BET; 1BND; 1BTG; 1HCF; 1NT3; 1SG1; 1SGF; 1WWW; 2IFG; 3BUK; 3IJ2; 4EAX; 4EC7;

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