Entry: PS00249

General information about the entry
Entry name PDGF_1
Accession number PS00249
Entry type PATTERN
Date APR-1990 (CREATED); DEC-2004 (DATA UPDATE); MAR-2013 (INFO UPDATE).
PROSITE Documentation PDOC00222
Name and characterization of the entry
DescriptionPlatelet-derived growth factor (PDGF) family signature.
Pattern P-[PSR]-C-V-x(3)-R-C-[GSTA]-G-C-C.
Numerical results
  • UniProtKB/Swiss-Prot release number: 2013_05, total number of sequence entries in that release: 540052.
  • Total number of hits in UniProtKB/Swiss-Prot: 60 hits in 60 different sequences
  • Number of hits on proteins that are known to belong to the set under consideration: 60 hits in 60 different sequences
  • Number of hits on proteins that could potentially belong to the set under consideration: 0 hits in 0 different sequences
  • Number of false hits (on unrelated proteins): 0 hits in 0 different sequences
  • Number of known missed hits: 10
  • Number of partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences: 1
  • Precision (true hits / (true hits + false positives)): 100.00 %
  • Recall (true hits / (true hits + false negatives)): 85.71 %
Comments
  • Taxonomic range: Eukaryotes, Eukaryotic viruses
  • Maximum known number of repetitions of the pattern in a single protein: 1
  • `Interesting' site in the pattern: 3,disulfide
  • `Interesting' site in the pattern: 7,disulfide
  • `Interesting' site in the pattern: 10,disulfide
  • `Interesting' site in the pattern: 11,disulfide
  • VERSION: 1
Cross-references
UniProtKB/Swiss-Prot True positive hits:
PDGFA_BOVIN (Q2KJ15), PDGFA_HUMAN (P04085), PDGFA_MOUSE (P20033), 
PDGFA_RABIT (P34007), PDGFA_RAT   (P28576), PDGFA_XENLA (P13698), 
PDGFB_CANFA (Q6Q7I7), PDGFB_FELCA (P12919), PDGFB_HUMAN (P01127), 
PDGFB_MOUSE (P31240), PDGFB_RAT   (Q05028), PDGFB_SHEEP (Q95229), 
PLGF_BOVIN  (Q9XS47), PLGF_HUMAN  (P49763), PLGF_MOUSE  (P49764), 
PLGF_RAT    (Q63434), TSIS_WMSV   (P01128), TXVE1_SISCA (B0VXV3), 
TXVE2_MACLB (P82475), TXVE2_PROMU (Q330K6), TXVE_AGKPI  (C0K3N2), 
TXVE_BITAR  (C0K3N1), TXVE_BOTER  (Q6J936), TXVE_BOTIN  (Q90X24), 
TXVE_BOTJA  (Q90X23), TXVE_CROAT  (C0K3N3), TXVE_DABRR  (P67861), 
TXVE_PROFL  (P67862), TXVE_SISCA  (B0VXV4), TXVE_VIPAA  (P67863), 
TXVE_VIPAP  (P83942), VEGFA_AGKPI (C0K3N4), VEGFA_BITGA (P83906), 
VEGFA_BOVIN (P15691), VEGFA_CANFA (Q9MYV3), VEGFA_CAVPO (P26617), 
VEGFA_CHICK (P67964), VEGFA_COTJA (P67965), VEGFA_HORSE (Q9GKR0), 
VEGFA_HUMAN (P15692), VEGFA_MESAU (Q99PS1), VEGFA_MOUSE (Q00731), 
VEGFA_PIG   (P49151), VEGFA_PROFL (P67860), VEGFA_RAT   (P16612), 
VEGFA_SHEEP (P50412), VEGFA_VIPAA (C0K3N5), VEGFB_BOVIN (Q9XS49), 
VEGFB_HUMAN (P49765), VEGFB_MOUSE (P49766), VEGFB_RAT   (O35485), 
VEGFC_HUMAN (P49767), VEGFC_MOUSE (P97953), VEGFC_RAT   (O35757), 
VEGFD_HUMAN (O43915), VEGFD_MOUSE (P97946), VEGFD_RAT   (O35251), 
VEGFH_ORFN2 (P52584), VEGFH_ORFN7 (P52585), VGFAA_DANRE (O73682)
False negative hits (sequences which belong to the set under consideration, but which have not been picked up by the pattern or profile):
PDGFC_CHICK (Q9I946), PDGFC_GECJA (A8WCC4), PDGFC_HUMAN (Q9NRA1), 
PDGFC_MOUSE (Q8CI19), PDGFC_RAT   (Q9EQX6), PDGFD_HUMAN (Q9GZP0), 
PDGFD_MOUSE (Q925I7), PDGFD_PONAB (Q5RA73), PDGFD_RABIT (Q6V9H4), 
PDGFD_RAT   (Q9EQT1)
`Potential' hits (partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences):
PDGFB_PIG   (P20034)
Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:

[Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format]

Retrieve the sequence logo from the alignment

PDB
[Detailed view]
1BJ1; 1CZ8; 1FLT; 1FZV; 1KAT; 1OWU; 1PDG; 1QTY; 1RV6; 1TZH; 1TZI; 1VPF; 1VPP; 1WQ8; 1WQ9; 2C7W; 2DZ4; 2DZ5; 2FJG; 2FJH; 2GNN; 2QR0; 2VPF; 2VWE; 2X1W; 2X1X; 2XAC; 2XV7; 3BDY; 3MJG; 3MJK; 3P9W; 3QTK; 3S1B; 3S1K; 3V2A; 3V6B; 4GLN; 4GLS; 4HQU; 4HQX;

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