Entry: PS00251

Forthcoming changes to the profile format
General information about the entry

Entry name [info] TNF_1
Accession [info] PS00251
Entry type [info] PATTERN
Date [info] APR-1990 (CREATED); DEC-2004 (DATA UPDATE); OCT-2014 (INFO UPDATE).
PROSITE Doc. [info] PDOC00224

Name and characterization of the entry

Description [info] TNF family signature.
Pattern [info]
[LV]-x-[LIVM]-{V}-x-{L}-G-[LIVMF]-Y-[LIVMFY](2)-x(2)-[QEKHL]-[LIVMGT]-x-
[LIVMFY].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2014_11 which contains 547'085 sequence entries.


Total number of hits 92 in 92 different sequences
Number of true positive hits 87 in 87 different sequences
Number of 'unknown' hits
Number of false positive hits 5 in 5 different sequences
Number of false negative sequences 16
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 94.57 %
Recall (true positives / (true positives + false negatives)) 84.47 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
87 sequences

CD40L_AOTTR (Q9BDM3), CD40L_BOVIN (P51749), CD40L_CALJA (Q9BDN3), 
CD40L_CANFA (O97626), CD40L_CERAT (P63305), CD40L_CHICK (Q9I8D8), 
CD40L_FELCA (O97605), CD40L_HUMAN (P29965), CD40L_MACMU (P63304), 
CD40L_MACNE (Q9BDM7), CD40L_MOUSE (P27548), CD40L_PIG   (Q95MQ5), 
CD40L_RAT   (Q9Z2V2), CD70_HUMAN  (P32970), TNF10_HUMAN (P50591), 
TNF10_MOUSE (P50592), TNF13_HUMAN (O75888), TNF13_MOUSE (Q9D777), 
TNFA_BOSIN  (P59684), TNFA_BOSTR  (Q1G1A2), TNFA_BOVIN  (Q06599), 
TNFA_BUBBU  (P59693), TNFA_BUBCA  (Q2MH05), TNFA_CALJA  (Q19LH4), 
TNFA_CAMBA  (Q75N23), TNFA_CANFA  (P51742), TNFA_CAPHI  (P13296), 
TNFA_CAVPO  (P51435), TNFA_CEREL  (P51743), TNFA_DASNO  (Q1WM27), 
TNFA_DELLE  (Q8WNR1), TNFA_FELCA  (P19101), TNFA_HORSE  (P29553), 
TNFA_HUMAN  (P01375), TNFA_LAMGL  (P59694), TNFA_MACEU  (O77764), 
TNFA_MACFA  (P79337), TNFA_MACMU  (P48094), TNFA_MARMO  (O35734), 
TNFA_MOUSE  (P06804), TNFA_PANTR  (Q8HZD9), TNFA_PAPAN  (P59695), 
TNFA_PAPHU  (O77510), TNFA_PAPSP  (P33620), TNFA_PERLE  (P36939), 
TNFA_PIG    (P23563), TNFA_RABIT  (P04924), TNFA_RAT    (P16599), 
TNFA_SAISC  (Q8MKG8), TNFA_SHEEP  (P23383), TNFA_TRIVU  (P79374), 
TNFA_TUPTA  (Q539C2), TNFA_TURTR  (Q9BEA1), TNFB_BOVIN  (Q06600), 
TNFB_CANFA  (Q5WR07), TNFB_HUMAN  (P01374), TNFB_MACEU  (Q9XT48), 
TNFB_MACMU  (Q5TM20), TNFB_MARMO  (Q9JM09), TNFB_MOUSE  (P09225), 
TNFB_PANTR  (P61125), TNFB_PIG    (P26445), TNFB_RABIT  (P10154), 
TNFB_RAT    (Q06332), TNFC_HUMAN  (Q06643), TNFC_MACEU  (Q9XT47), 
TNFC_MACMU  (Q5TM22), TNFC_MOUSE  (P41155), TNFC_PANTR  (Q862Z7), 
TNFC_PIG    (Q9TSV8), TNFL4_HUMAN (P23510), TNFL4_MOUSE (P43488), 
TNFL4_RABIT (O02765), TNFL4_RAT   (Q9Z2P3), TNFL6_CERAT (Q9BDN1), 
TNFL6_FELCA (Q861W5), TNFL6_HUMAN (P48023), TNFL6_MACFA (P63308), 
TNFL6_MACMU (P63307), TNFL6_MACNE (P63306), TNFL6_MOUSE (P41047), 
TNFL6_PIG   (Q9BEA8), TNFL6_RAT   (P36940), TNFL8_HUMAN (P32971), 
TNFL8_MOUSE (P32972), TNFL9_HUMAN (P41273), TNFL9_MOUSE (P41274)
» More

UniProtKB/Swiss-Prot
False negative sequences
16 sequences

EDA_BOVIN   (Q9BEG5), EDA_HUMAN   (Q92838), EDA_MOUSE   (O54693), 
TN13B_HUMAN (Q9Y275), TN13B_MOUSE (Q9WU72), TNF11_HUMAN (O14788), 
TNF11_MOUSE (O35235), TNF11_RAT   (Q9ESE2), TNF12_HUMAN (O43508), 
TNF12_MOUSE (O54907), TNF14_HUMAN (O43557), TNF14_MOUSE (Q9QYH9), 
TNF18_HUMAN (Q9UNG2), TNF18_MOUSE (Q7TS55), TNFA_SPAAU  (Q8JFG3), 
TNFC_MARMO  (Q9JM10)
» More

UniProtKB/Swiss-Prot
False positive sequences
5 sequences

ATP6_VANPO  (A6H4Q8), LIVH_METJA  (Q58665), LNT2_LEPIC  (Q72MD8), 
LNT2_LEPIN  (Q8EYY4), PCID2_DROME (Q9VTL1)
» More


View entry in original PROSITE format
View entry in raw text format (no links)
Direct ScanProsite submission