Entry: PS00254

General information about the entry
Entry name INTERLEUKIN_6
Accession number PS00254
Entry type PATTERN
Date APR-1990 (CREATED); APR-1990 (DATA UPDATE); APR-2013 (INFO UPDATE).
PROSITE Documentation PDOC00227
Name and characterization of the entry
DescriptionInterleukin-6 / G-CSF / MGF signature.
Pattern C-x(9)-C-x(6)-G-L-x(2)-[FY]-x(3)-L.
Numerical results
  • UniProtKB/Swiss-Prot release number: 2013_06, total number of sequence entries in that release: 540261.
  • Total number of hits in UniProtKB/Swiss-Prot: 37 hits in 37 different sequences
  • Number of hits on proteins that are known to belong to the set under consideration: 37 hits in 37 different sequences
  • Number of hits on proteins that could potentially belong to the set under consideration: 0 hits in 0 different sequences
  • Number of false hits (on unrelated proteins): 0 hits in 0 different sequences
  • Number of known missed hits: 3
  • Number of partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences: 0
  • Precision (true hits / (true hits + false positives)): 100.00 %
  • Recall (true hits / (true hits + false negatives)): 92.50 %
Comments
  • Taxonomic range: Eukaryotes
  • Maximum known number of repetitions of the pattern in a single protein: 1
  • `Interesting' site in the pattern: 1,disulfide
  • `Interesting' site in the pattern: 3,disulfide
  • VERSION: 1
Cross-references
UniProtKB/Swiss-Prot True positive hits:
CSF3_BOVIN  (P35833), CSF3_CANFA  (P35834), CSF3_FELCA  (O02708), 
CSF3_HUMAN  (P09919), CSF3_MOUSE  (P09920), CSF3_PIG    (O02837), 
CSF3_SHEEP  (Q28746), IL6_BOVIN   (P26892), IL6_BUBBU   (Q6V919), 
IL6_BUBCA   (Q2MH06), IL6_CAMBA   (Q865W7), IL6_CANFA   (P41323), 
IL6_CAPHI   (Q28319), IL6_CERAT   (P46650), IL6_CHICK   (Q90YI0), 
IL6_DELLE   (Q9XT80), IL6_FELCA   (P41683), IL6_HORSE   (Q95181), 
IL6_HUMAN   (P05231), IL6_LAMGL   (Q865X6), IL6_MACFA   (P79341), 
IL6_MACMU   (P51494), IL6_MACTH   (Q5I6E3), IL6_MARMO   (O35736), 
IL6_MOUSE   (P08505), IL6_MUSPF   (A3FBE9), IL6_NEOVI   (P41693), 
IL6_ORCOR   (Q28747), IL6_PHOVI   (Q28819), IL6_PIG     (P26893), 
IL6_RABIT   (Q9MZR1), IL6_RAT     (P20607), IL6_SAISC   (Q8MKH0), 
IL6_SHEEP   (P29455), IL6_TAKRU   (Q6L6X6), IL6_VULVU   (Q25BC2), 
MGF_CHICK   (P13854)
False negative hits (sequences which belong to the set under consideration, but which have not been picked up by the pattern or profile):
IL6_ONCMY   (Q0GGL7), IL6_PAROL   (A0S0B0), IL6_SPAAU   (B6CKP4)
Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:

[Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format]

Retrieve the sequence logo from the alignment

PDB
[Detailed view]		 1ALU; 1BGC; 1BGD; 1BGE; 1CD9; 1GNC; 1IL6; 1N2Q; 1P9M; 1PGR; 1RHG; 2D9Q; 2IL6; 2L3Y;

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