Entry: PS00254

General information about the entry

Entry name [info] INTERLEUKIN_6
Accession [info] PS00254
Entry type [info] PATTERN
Date [info] APR-1990 (CREATED); APR-1990 (DATA UPDATE); MAR-2016 (INFO UPDATE).
PROSITE Doc. [info] PDOC00227

Name and characterization of the entry

Description [info] Interleukin-6 / G-CSF / MGF signature.
Pattern [info]

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2016_04 which contains 550'960 sequence entries.

Total number of hits 37 in 37 different sequences
Number of true positive hits 37 in 37 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 3
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 92.50 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Site [info] disulfide at position 1
Site [info] disulfide at position 3
Version [info] 1

Cross-references [info]

True positive sequences
37 sequences

CSF3_BOVIN  (P35833), CSF3_CANLF  (P35834), CSF3_FELCA  (O02708), 
CSF3_HUMAN  (P09919), CSF3_MOUSE  (P09920), CSF3_PIG    (O02837), 
CSF3_SHEEP  (Q28746), IL6_BOVIN   (P26892), IL6_BUBBU   (Q6V919), 
IL6_BUBCA   (Q2MH06), IL6_CAMBA   (Q865W7), IL6_CANLF   (P41323), 
IL6_CAPHI   (Q28319), IL6_CERAT   (P46650), IL6_CHICK   (Q90YI0), 
IL6_DELLE   (Q9XT80), IL6_FELCA   (P41683), IL6_HORSE   (Q95181), 
IL6_HUMAN   (P05231), IL6_LAMGL   (Q865X6), IL6_MACFA   (P79341), 
IL6_MACMU   (P51494), IL6_MACTH   (Q5I6E3), IL6_MARMO   (O35736), 
IL6_MOUSE   (P08505), IL6_MUSPF   (A3FBE9), IL6_NEOVI   (P41693), 
IL6_ORCOR   (Q28747), IL6_PHOVI   (Q28819), IL6_PIG     (P26893), 
IL6_RABIT   (Q9MZR1), IL6_RAT     (P20607), IL6_SAISC   (Q8MKH0), 
IL6_SHEEP   (P29455), IL6_TAKRU   (Q6L6X6), IL6_VULVU   (Q25BC2), 
MGF_CHICK   (P13854)
» more

False negative sequences
3 sequences

IL6_ONCMY   (Q0GGL7), IL6_PAROL   (A0S0B0), IL6_SPAAU   (B6CKP4)

[Detailed view]
18 PDB

1ALU; 1BGC; 1BGD; 1BGE; 1CD9; 1GNC; 1IL6; 1P9M; 1PGR; 1RHG; 2D9Q; 2IL6; 2L3Y; 4CNI; 4J4L; 4NI7; 4NI9; 4O9H
» more

View entry in original PROSITE format
View entry in raw text format (no links)
Direct ScanProsite submission