Entry: PS00266

General information about the entry
Entry name SOMATOTROPIN_1
Accession number PS00266
Entry type PATTERN
Date APR-1990 (CREATED); DEC-2004 (DATA UPDATE); MAR-2013 (INFO UPDATE).
PROSITE Documentation PDOC00239
Name and characterization of the entry
DescriptionSomatotropin, prolactin and related hormones signature 1.
Pattern C-x-[STN]-x(2)-[LIVMFYS]-x-[LIVMSTA]-P-x(5)-[TALIV]-x(7)-[LIVMFY]-x(6)- [LIVMFY]-x(2)-[STACV]-W.
Numerical results
  • UniProtKB/Swiss-Prot release number: 2013_05, total number of sequence entries in that release: 540052.
  • Total number of hits in UniProtKB/Swiss-Prot: 195 hits in 195 different sequences
  • Number of hits on proteins that are known to belong to the set under consideration: 189 hits in 189 different sequences
  • Number of hits on proteins that could potentially belong to the set under consideration: 0 hits in 0 different sequences
  • Number of false hits (on unrelated proteins): 6 hits in 6 different sequences
  • Number of known missed hits: 25
  • Number of partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences: 2
  • Precision (true hits / (true hits + false positives)): 96.92 %
  • Recall (true hits / (true hits + false negatives)): 88.32 %
Comments
  • Taxonomic range: Eukaryotes
  • Maximum known number of repetitions of the pattern in a single protein: 1
  • `Interesting' site in the pattern: 1,disulfide
  • VERSION: 1
Cross-references
UniProtKB/Swiss-Prot True positive hits:
CSH1_BOVIN  (P09611), CSH2_BOVIN  (P19159), CSH_HUMAN   (P01243), 
CSH_SHEEP   (P16038), PLRP1_BOVIN (P05402), PLRP2_BOVIN (P12401), 
PLRP3_BOVIN (P12402), PR2A1_MOUSE (Q9JHK0), PR2C2_MOUSE (P04095), 
PR2C3_MOUSE (P04768), PR3B1_MESAU (P14059), PR3B1_MOUSE (P09586), 
PR3B1_RAT   (P09321), PR3D1_MOUSE (P18121), PR3D1_RAT   (P21702), 
PR3D4_RAT   (P34207), PR4A1_MOUSE (O35256), PR4A1_RAT   (P09320), 
PR7B1_MOUSE (Q8CGZ9), PR7B1_RAT   (Q8CJ42), PR7C1_MOUSE (Q9CRB5), 
PR7D1_MOUSE (P04769), PRL1_ALLMI  (P55751), PRL1_CRONO  (P55753), 
PRL1_ONCKE  (P69130), PRL1_ONCTS  (P69131), PRL1_OREMO  (P09319), 
PRL2_ALLMI  (P55752), PRL2_CRONO  (P55754), PRL2_ONCKE  (P09584), 
PRL2_ONCTS  (Q91364), PRL2_OREMO  (P09318), PRL_AILME   (Q8HXS1), 
PRL_ANGAN   (P33096), PRL_ANGJA   (Q7ZZV3), PRL_BALBO   (P33089), 
PRL_BOVIN   (P01239), PRL_CAMDR   (P22393), PRL_CAPHI   (Q28318), 
PRL_CARAU   (P87495), PRL_CEREL   (Q6UC74), PRL_CHEMY   (P33090), 
PRL_CHICK   (P14676), PRL_CORAU   (P34181), PRL_CYPCA   (P09585), 
PRL_DICLA   (P48249), PRL_FELCA   (P46403), PRL_HORSE   (P12420), 
PRL_HUMAN   (P01236), PRL_HYPMO   (P35395), PRL_HYPNO   (P29235), 
PRL_ICTPU   (P51904), PRL_ISOMA   (Q3Y4G6), PRL_LOXAF   (P10765), 
PRL_MACMU   (P55151), PRL_MELGA   (P17572), PRL_MESAU   (P37884), 
PRL_MICMO   (Q9QZL1), PRL_MONDO   (O62819), PRL_NEOVI   (P29234), 
PRL_ONCMY   (P21993), PRL_PAROL   (Q9YGV6), PRL_PIG     (P01238), 
PRL_PROAT   (P33091), PRL_RABIT   (Q28632), PRL_RAT     (P01237), 
PRL_SALSA   (P48096), PRL_SHEEP   (P01240), PRL_SPAAU   (O93337), 
PRL_TRIVU   (O62781), SOM2_HUMAN  (P01242), SOM2_MACMU  (Q07370), 
SOM2_PANTR  (P58757), SOMA1_ACIGU (P26773), SOMA1_CARAU (O93359), 
SOMA1_ONCMY (P09538), SOMA1_ONCNE (Q91222), SOMA2_ACIGU (P26774), 
SOMA2_CARAU (O93360), SOMA2_ONCMY (P20332), SOMA2_ONCNE (Q91221), 
SOMA2_XENLA (P12856), SOMA_ACABU  (Q01282), SOMA_ACALA  (P45654), 
SOMA_AILME  (Q8HYE5), SOMA_ANAPL  (P11228), SOMA_ANGJA  (P08899), 
SOMA_BALBO  (P33092), SOMA_BALPH  (Q659Q8), SOMA_BOSGF  (Q1HFN3), 
SOMA_BOSMU  (Q864S7), SOMA_BOVIN  (P01246), SOMA_BUBBU  (O18938), 
SOMA_BUFMA  (O73849), SOMA_CALJA  (Q9GMB3), SOMA_CAMDR  (Q7YRR6), 
SOMA_CANFA  (P33711), SOMA_CAPHI  (P67931), SOMA_CAVPO  (Q9JKM4), 
SOMA_CEREL  (P56437), SOMA_CHEMY  (P34005), SOMA_CHICK  (P08998), 
SOMA_CORAU  (P45655), SOMA_CORLV  (O13188), SOMA_CRONO  (P55755), 
SOMA_CTEID  (P69158), SOMA_CYPCA  (P10298), SOMA_DELDE  (Q8MI73), 
SOMA_DICLA  (Q05163), SOMA_ESOLU  (P34744), SOMA_FELCA  (P46404), 
SOMA_GALSE  (Q9GKA1), SOMA_GIRCA  (Q7YQD2), SOMA_HETFO  (Q9W6R8), 
SOMA_HIPAM  (Q7YQB8), SOMA_HORSE  (P01245), SOMA_HUMAN  (P01241), 
SOMA_HYPMO  (P69159), SOMA_HYPNO  (P69160), SOMA_ICTPU  (P34745), 
SOMA_KATPE  (P20391), SOMA_LABRO  (Q9W6J7), SOMA_LAMPA  (P37885), 
SOMA_LARCR  (Q9I9M4), SOMA_LATCA  (Q01283), SOMA_LEPOS  (P79885), 
SOMA_LITCT  (P10813), SOMA_LOXAF  (P20392), SOMA_MACMU  (P33093), 
SOMA_MELGA  (P22077), SOMA_MESAU  (P37886), SOMA_MISMI  (Q9W6J5), 
SOMA_MONDO  (Q9GL60), SOMA_MORSA  (P48248), SOMA_MOUSE  (P06880), 
SOMA_NEOVI  (P19795), SOMA_NYCPY  (Q9GMB2), SOMA_ODOAR  (Q9I9L5), 
SOMA_ONCKE  (P07064), SOMA_ONCKI  (P10607), SOMA_ONCMA  (Q9DGG5), 
SOMA_ONCTS  (Q07221), SOMA_OREMO  (P34746), SOMA_ORENI  (P13391), 
SOMA_PAGMA  (P08591), SOMA_PANGG  (P69162), SOMA_PANPG  (P69161), 
SOMA_PANTR  (P58756), SOMA_PAROL  (P09537), SOMA_PERFV  (Q9DEV3), 
SOMA_PIG    (P01248), SOMA_PRIGL  (P34006), SOMA_PROAN  (O73848), 
SOMA_PSEDN  (P24363), SOMA_RABIT  (P46407), SOMA_RAT    (P01244), 
SOMA_SAIBB  (P58343), SOMA_SALSA  (P10814), SOMA_SCIOC  (Q9IB11), 
SOMA_SEBSC  (P87391), SOMA_SERQU  (P09539), SOMA_SHEEP  (P67930), 
SOMA_SIGGU  (Q9IBE5), SOMA_SOLSE  (P45643), SOMA_SPAAU  (P29971), 
SOMA_SPAEH  (O70615), SOMA_STRCA  (Q9PWG3), SOMA_TAKRU  (O12980), 
SOMA_THUAL  (P34747), SOMA_THUTH  (P09113), SOMA_TRITC  (Q98UF6), 
SOMA_TRIVU  (O62754), SOMA_VERVA  (O93566), SOMA_VULVU  (P10766), 
SOML1_SPAAU (P54863), SOML2_SPAAU (P79894), SOML_ACITR  (O93262), 
SOML_CYCLU  (P45640), SOML_GADMO  (P21919), SOML_HIPHI  (P45641), 
SOML_ICTPU  (Q9I8J9), SOML_ONCKE  (P24405), SOML_ORYLA  (Q6E211), 
SOML_PAROL  (P20362), SOML_PROAN  (O73847), SOML_SCIOC  (Q9YGK7), 
SOML_SIGGU  (Q9PWG4), SOML_SOLSE  (P45642), SOML_TETMU  (Q9I9H4)
False negative hits (sequences which belong to the set under consideration, but which have not been picked up by the pattern or profile):
CSHL_HUMAN  (Q14406), PLRP4_BOVIN (P18917), PR2A1_RAT   (Q9JII3), 
PR2B1_MOUSE (Q9DAZ2), PR2B1_RAT   (Q9JKL9), PR3C1_MOUSE (Q9QUN5), 
PR3C1_RAT   (Q9QUL0), PR5A1_MOUSE (Q9JII2), PR5A1_RAT   (Q9JII4), 
PR6A1_MOUSE (O35257), PR6A1_RAT   (P24800), PR7A1_MOUSE (O54830), 
PR7A2_MOUSE (O54831), PR7A2_RAT   (Q9R006), PR8A4_RAT   (P33580), 
PR8A5_RAT   (P33579), PR8A6_MOUSE (Q9DAY2), PR8A7_RAT   (P33578), 
PR8A8_MOUSE (Q9DAS4), PR8A9_MOUSE (Q9CQ58), PR8A9_RAT   (Q920I0), 
PRL_MOUSE   (P06879), SOMA1_XENLA (P12855), SOML_ANGAN  (Q90216), 
SOML_CARAU  (P79697)
`Potential' hits (partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences):
GHR4_RAT    (P33581), PRL_BUFJA   (P43001)
False positive hits (sequences which do not belong to the set under consideration):
GD_HHV11    (Q69091), GD_HHV1A    (P36318), GD_HHV1F    (Q05059), 
GD_HHV1H    (P06476), GD_HHV1K    (A1Z0Q5), GD_HHV1P    (P57083)
Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:

[Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format]

Retrieve the sequence logo from the alignment

PDB
[Detailed view]		 1A22; 1AN3; 1AXI; 1BP3; 1BST; 1F6F; 1HGU; 1HUW; 1HWG; 1HWH; 1KF9; 1RW5; 2Q98; 3D48; 3EW3; 3HHR; 3MZG; 3N06; 3N0P; 3NCB; 3NCC; 3NCE; 3NCF; 3NPZ;

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